Antibody-Mediated Pathogen Resistance in Plants

The methods described in this chapter were developed in order to produce transgenic plants expressing pathogen-specific single-chain variable fragment (scFv) antibodies fused to antifungal peptides (AFPs), conferring resistance against fungal pathogens. We describe the selection from a phage display library of avian scFv antibodies that recognize cell surface proteins on fungi from the genus Fusarium, and the construction of scFv–AFP fusion protein constructs followed by their transient expression in tobacco (Nicotiana spp.) plants and stable expression in Arabidopsis thaliana plants. Using these techniques, the antibody fusion with the most promising in vitro activity can be used to generate transgenic plants that are resistant to pathogens such as Fusarium oxysporum f. sp. matthiolae

Linear basal cell carcinoma: A distinct clinical entity

Copyright © 2005 The British Association of Plastic Surgeons Published by Elsevier LtdThe purpose of the study is to describe linear basal cell carcinoma (BCC) as a distinct clinical entity, and highlight its existence to the plastic surgery literature. A Medline and PubMed literature search was conducted, and 33 reported cases of linear BCC were analysed. Of these 33 cases, the most common site for linear BCC was the periocular region, accounting for 49% (n=16). The most common histologic subtype, was nodular BCC, accounting for 50% (n=17). Of the 33 reported cases the postoperative defect size was mentioned in five cases only. None of these would have been completely excised if a 2 mm margin was applied, and only one out of five if a 4 mm margin was applied. Linear BCC is a distinct clinical entity. Presence of the tumour along relaxing skin tension lines, increase in subclinical extension, and aggressive tumour behavior are reported observations. Because of these observations it is suggested that margin-controlled excision should be considered for linear BCC.I. Mavrikakis, R. Malhotra, D. Selva, S.C. Huilgol and R. Barlo

За кадры. 1970. № 27 (1462)

Победители соревнования. Впереди идут ФТФ, ЭМФ, ХТФ / А. Гагарин [и др.]Человек высокого долга / А. ПортягинНужна перестройка / М. Ф. ПолетикаПамятник ко дню Победы / Р. Горская"Вестник высшей школы". Краткий обзорСтуденческая юбилейная / О. СтепановаБригантина поднимат паруса / Н. ФедороваДождь и снег - не помеха / О. ВолодинаЕсли готовите снимок на выставку... / Г. ХлопковНе выходят на благоустройство / Б. ДерчанскийКомнату - на все пять летВесенняя лирика. Тяжелый снег пропитан соком... / С. ЯковлевВесенняя лирика. Граница - это не только нейтраль... / В. БояриновВесенняя лирика. В тебе мне нравится твоя твердость... / А. ШипелеваВесенняя лирика. Короткий разговор / О. ФедюшинаНаедине с природой / А. СобанинДебоширы наказаны / И. И. КаляцкийНовые книги о В. И. ЛенинеНа первом месте - комсомольцы АВТФ / Г. Гогу