International education: a force for peace and cross-cultural understanding?

This paper discusses the notion that the international sojourn has the potential to transform sojourners into cultural mediators who carry the power to improve global relations. A year-long ethnographic study of the adjustment experiences of international postgraduate students in England revealed a universal early enthusiasm for cross-cultural contact that was matched by a widespread adoption of segregated patterns of interacting. The most common friendship networks were described by bonds with conationals, and yet all students attested to an increase in their cultural learning and mindfulness by the end of the sojourn. Nevertheless, intercultural competence was maximised only in those few students who pursued a multicultural strategy of interaction, leading the researcher to call on Higher Education Institutions to instigate policies to encourage lasting cross-cultural contact

Edge stabilization in reduced-dimensional perovskites

Reduced-dimensional perovskites are attractive light-emitting materials due to their efficient luminescence, color purity, tunable bandgap, and structural diversity. A major limitation in perovskite light-emitting diodes is their limited operational stability. Here we demonstrate that rapid photodegradation arises from edge-initiated photooxidation, wherein oxidative attack is powered by photogenerated and electrically-injected carriers that diffuse to the nanoplatelet edges and produce superoxide. We report an edge-stabilization strategy wherein phosphine oxides passivate unsaturated lead sites during perovskite crystallization. With this approach, we synthesize reduced-dimensional perovskites that exhibit 97 ± 3% photoluminescence quantum yields and stabilities that exceed 300 h upon continuous illumination in an air ambient. We achieve green-emitting devices with a peak external quantum efficiency (EQE) of 14% at 1000 cd m-2; their maximum luminance is 4.5 × 104 cd m-2 (corresponding to an EQE of 5%); and, at 4000 cd m-2, they achieve an operational half-lifetime of 3.5 h.This publication is based in part on work supported by an award (KUS-11-009-21) from the King Abdullah University of Science and Technology (KAUST), by the Ontario Research Fund Research Excellence Program, by the Ontario Research Fund (ORF), by the Natural Sciences and Engineering Research Council (NSERC) of Canada, and by the US Department of Navy, Office of Naval Research (Grant Award No. N00014-17-1-2524). H.Y. acknowledges the Research Foundation-Flanders (FWO Vlaanderen) for a postdoctoral fellowship. E.B. gratefully acknowledges financial support by the Research Foundation-Flanders (FWO Vlaanderen). S.B. acknowledges financial support from European Research Council (ERC Starting Grant #815128-REALNANO). M.B.J.R. and J.H. acknowledge the Research Foundation-Flanders (FWO, Grants G.0962.13, G.0B39.15, AKUL/11/14 and G0H6316N), KU Leuven Research Fund (C14/15/053) and the European Research Council under the European Union’s Seventh Framework Programme (FP/2007-2013)/ERC Grant Agreement No. [307523], ERC-Stg LIGHT to M.B.J.R. DFT calculations were performed on the IBM BlueGene Q supercomputer with support from the Southern Ontario Smart Computing Innovation Platform (SOSCIP). M.I.S. acknowledges the Banting Postdoctoral Fellowship program from the Natural Sciences and Engineering Research Council of Canada (NSERC). H.T. acknowledges the Netherlands Organisation for Scientific Research (NWO) for a Rubicon grant (680-50-1511)

Beyond the 'Grid-Lock' in Electricity Interconnectors: The Case of Germany and Poland

The common European electricity market requires both market integration and transmission grid expansion, including trans-border interconnectors. Although the benefits of increased interconnectivity are widely acknowledged, expansion of interconnectors is often very slow. This paper gathers insights on the reasons behind this grid-lock drawing on the study of the German-Polish border. Although two interconnectors already exist, the trade is blocked by unplanned electricity loop flows. A third interconnector has been discussed for years, but saw little progress in spite of declarations of support on both sides. Drawing on the existing literature on the topic of grid expansion we identify four hypotheses for the grid-lock: inadequate financing; diverging interests; governance and administration problems; and different actors' motivations, trust and security perceptions. We evaluate them using the empirical material gathered through document analysis and stakeholder interviews conducted in Germany and Poland. None of the hypotheses on its own can explain the gridlock. However, while financing has not been a major obstacle, divergent interests had an impact on the project delay, administrative and governance problems are a great hindrance on the technical level, while motivations influence interstate political relations and policy shaping. EU support and closer bilateral cooperation provide opportunities to address these challenges

Evidence for Reductive Genome Evolution and Lateral Acquisition of Virulence Functions in Two Corynebacterium pseudotuberculosis Strains

Ruiz JC, D'Afonseca V, Silva A, et al. Evidence for Reductive Genome Evolution and Lateral Acquisition of Virulence Functions in Two Corynebacterium pseudotuberculosis Strains. PLoS ONE. 2011;6(4): e18551.Background: Corynebacterium pseudotuberculosis, a Gram-positive, facultative intracellular pathogen, is the etiologic agent of the disease known as caseous lymphadenitis (CL). CL mainly affects small ruminants, such as goats and sheep; it also causes infections in humans, though rarely. This species is distributed worldwide, but it has the most serious economic impact in Oceania, Africa and South America. Although C. pseudotuberculosis causes major health and productivity problems for livestock, little is known about the molecular basis of its pathogenicity. Methodology and Findings: We characterized two C. pseudotuberculosis genomes (Cp1002, isolated from goats; and CpC231, isolated from sheep). Analysis of the predicted genomes showed high similarity in genomic architecture, gene content and genetic order. When C. pseudotuberculosis was compared with other Corynebacterium species, it became evident that this pathogenic species has lost numerous genes, resulting in one of the smallest genomes in the genus. Other differences that could be part of the adaptation to pathogenicity include a lower GC content, of about 52%, and a reduced gene repertoire. The C. pseudotuberculosis genome also includes seven putative pathogenicity islands, which contain several classical virulence factors, including genes for fimbrial subunits, adhesion factors, iron uptake and secreted toxins. Additionally, all of the virulence factors in the islands have characteristics that indicate horizontal transfer. Conclusions: These particular genome characteristics of C. pseudotuberculosis, as well as its acquired virulence factors in pathogenicity islands, provide evidence of its lifestyle and of the pathogenicity pathways used by this pathogen in the infection process. All genomes cited in this study are available in the NCBI Genbank database (http://www.ncbi.nlm.nih.gov/genbank/) under accession numbers CP001809 and CP001829

Wissenschaftliche Kompetenzen in der Versorgungsforschung - Kenntnisse, Anwendung und Bedürfnisse hinsichtlich Fortbildungen von Mitarbeitenden des Universitätsklinikums Tübingen

Objectives: As part of the further development of an existing training program on scientific skills for health services research at the University Hospital Tübingen, the aim of the study is to determine the level of knowledge, utilization and needs for continuing education among staff.Methods: In 2022, a semi standardized anonymous cross-sectional survey was conducted at the University Hospital Tübingen. The content of the questionnaire survey was the level of knowledge and utilization of various research methods, the need for continuing education on these and other healthcare research-related topics and the preferred training concept. The data analysis was carried out descriptively based on absolute and relative frequencies overall and grouped according to the scientific experience of the participants.Results: Participants' self-assessment indicated that a proportion of them had research skills. However, the level of knowledge and utilization varied greatly with regard to different research methods. The 222 participants most frequently expressed a desire for continuing education in the preparation of meta-analyses (56%), questionnaire validation (43%) and -development (42%). There was also great interest in continuing education in the fields of project coordination (57%), third-party funded projects (46%) and science communication (45%).Conclusion: The survey highlights existing research skills and the need for methodological qualification in the field of healthcare research among the staff of the University Hospital Tübingen. The focus appears to be on evidence generation, methods of empirical social research and general research-related skills. The results will be used to design new training courses with a focus on health services research.Zielsetzung: Am Universitätsklinikum Tübingen (UKT) werden bestehende Fortbildungsangebote zu wissenschaftlichen Kompetenzen in der Versorgungsforschung weiterentwickelt. Ziel der Studie ist es den Kenntnisstand, Anwendung und Bedürfnisse hinsichtlich Fortbildungen bei den Beschäftigten zu ermitteln.Methodik: 2022 wurde am UKT eine teilstandardisierte anonyme Querschnittsbefragung durchgeführt. Inhalt der Fragebogenerhebung war der Kenntnis- und Anwendungsstand hinsichtlich verschiedener Forschungsmethoden, das Bedürfnis nach Fortbildungen zu diesen und weiteren versorgungsforschungsnahen Themen sowie die präferierte Fortbildungskonzeption. Die Auswertung erfolgte deskriptiv anhand absoluter und relativer Häufigkeiten insgesamt sowie gruppiert nach wissenschaftlicher Erfahrung der Teilnehmenden.Ergebnisse: Die Selbsteinschätzung der Teilnehmenden zeigte, dass anteilig Forschungskompetenzen vorlagen. Der Kenntnis- und Anwendungsstand variierte stark in Bezug auf verschiedene Forschungsmethoden. Die 222 Teilnehmenden äußerten am häufigsten den Wunsch nach Fortbildungen zur Erstellung von Metaanalysen (56%), Fragebogenvalidierung (43%) und -entwicklung (42%). Großes Interesse bestand zudem an Fortbildungen zu Projektkoordination (57%), Drittmittelprojekte (46%) sowie Wissenschaftskommunikation (45%). Schlussfolgerung: Die Erhebung verdeutlicht bestehende Forschungskompetenzen und das Bedürfnis nach methodischer Qualifizierung im Bereich der Versorgungsforschung bei Beschäftigten des UKT. Hierbei scheint ein Schwerpunkt auf der Evidenzgenerierung, Methoden der empirischen Sozialforschung und allgemeinen forschungsbezogenen Kompetenzen zu liegen. Die Ergebnisse werden für die Konzeption neuer Fortbildungen mit Fokus auf Versorgungsforschung verwendet

Yeast volatiles double starvation survival in <i>Drosophila</i>

Yeast volatiles double starvation survival in Drosophila . </jats:p