WISE Circumstellar Disks in the Young Sco-Cen Association

We present an analysis of the WISE photometric data for 829 stars in the Sco-Cen OB2 association, using the latest high-mass membership probabilities. We detect infrared excesses associated with 135 BAF-type stars, 99 of which are secure Sco-Cen members. There is a clear increase in excess fraction with membership probability, which can be fitted linearly. We infer that 41+-5% of Sco-Cen OB2 BAF stars to have excesses, while the field star excess fraction is consistent with zero. This is the first time that the probability of non-membership has been used in the calculation of excess fractions for young stars. We do not observe any significant change in excess fraction between the three subgroups. Within our sample, we have observed that B-type association members have a significantly smaller excess fraction than A and F-type association members.Comment: 5 Pages, 3 figure, 4 tables. Complete table 1 included. Accepted to MNRAS Letter

Analysis on the hull girder ultimate strength of a bulk carrier using simplified method based on an incremental-iterative approach

The hull girder ultimate strength of a typical bulk carrier is analyzed using a simplified method based on an incremental-iterative approach. First, vertical bending moment is examined by seven different methods. The moment versus curvature curves and the values of the ultimate longitudinal moments at collapse states are determined for both hogging and sagging cases. Second, the ultimate strength under coupled vertical and horizontal bending moment is accounted. An interaction curve is obtained, which corresponds to the results of series of calculation for the ship hull subject to bending conditions with different angles of curvature. It is found that the interaction curve is asymmetrical because the hull cross section is not symmetrical with respect to the horizontal axis and the structural response of the elements under compression is different from that under tension due to nonlinearity caused by buckling. The angles of the resultant bending moment vector and that of the curvature vector are different in investigated cases. The interaction design equations proposed by other researches are also addressed to discuss the results presented by this study

Testing the gamma-ray burst variability/peak luminosity correlation on a Swift homogeneous sample

We test the gamma-ray burst correlation between temporal variability and peak luminosity of the $\gamma$-ray profile on a homogeneous sample of 36 Swift/BAT GRBs with firm redshift determination. This is the first time that this correlation can be tested on a homogeneous data sample. The correlation is confirmed, as long as the 6 GRBs with low luminosity (<5x10^{50} erg s^{-1} in the rest-frame 100-1000 keV energy band) are ignored. We confirm that the considerable scatter of the correlation already known is not due to the combination of data from different instruments with different energy bands, but it is intrinsic to the correlation itself. Thanks to the unprecedented sensitivity of Swift/BAT, the variability/peak luminosity correlation is tested on low-luminosity GRBs. Our results show that these GRBs are definite outliers.Comment: Accepted for Publication in MNRAS. 10 pages, 5 figures, 3 table

Nonlocal field correlations and dynamical Casimir-Polder forces between one excited- and two ground-state atoms

The problem of nonlocality in the dynamical three-body Casimir-Polder interaction between an initially excited and two ground-state atoms is considered. It is shown that the nonlocal spatial correlations of the field emitted by the excited atom during the initial part of its spontaneous decay may become manifest in the three-body interaction. The observability of this new phenomenon is discussed.Comment: 17 pages, 1 figure, sub. to Phys. Rev.

Dynamical Casimir-Polder interaction between an atom and surface plasmons

We investigate the time-dependent Casimir-Polder potential of a polarizable two-level atom placed near a surface of arbitrary material, after a sudden change in the parameters of the system. Different initial conditions are taken into account. For an initially bare ground-state atom, the time-dependent Casimir-Polder energy reveals how the atom is "being dressed" by virtual, matter-assisted photons. We also study the transient behavior of the Casimir-Polder interaction between the atom and the surface starting from a partially dressed state, after an externally induced change in the atomic level structure or transition dipoles. The Heisenberg equations are solved through an iterative technique for both atomic and field operators in the medium-assisted electromagnetic field quantization scheme. We analyze in particular how the time evolution of the interaction energy depends on the optical properties of the surface, in particular on the dispersion relationof surface plasmon polaritons. The physical significance and the limits of validity of the obtained results are discussed in detail.Comment: 12 pages, 8 figure

The endogenous caspase-8 inhibitor c-FLIPL regulates ER morphology and crosstalk with mitochondria

Components of the death receptors-mediated pathways like caspase-8 have been identified in complexes at intracellular membranes to spatially restrict the processing of local targets. In this study, we report that the long isoform of the cellular FLICE-inhibitory protein (c-FLIPL), a well- known inhibitor of the extrinsic cell death initiator caspase-8, localizes at the endoplasmic reticulum (ER) and mitochondria-associated membranes (MAMs). ER morphology was disrupted and ER Ca2+-release as well as ER-mitochondria tethering were decreased in c-FLIP-/- mouse embryonic fibroblasts (MEFs). Mechanistically, c-FLIP ablation resulted in enhanced basal caspase-8 activation and in caspase-mediated processing of the ER-shaping protein reticulon-4 (RTN4) that was corrected by re-introduction of c-FLIPL and caspase inhibition, resulting in the recovery of a normal ER morphology and ER-mitochondria juxtaposition. Thus, the caspase-8 inhibitor c-FLIPL emerges as a component of the MAMs signaling platforms, where caspases appear to regulate ER morphology and ER-mitochondria crosstalk by impinging on ER-shaping proteins like the RTN4

Ripple oscillations in the left temporal neocortex are associated with impaired verbal episodic memory encoding

Background: We sought to determine if ripple oscillations (80-120Hz), detected in intracranial EEG (iEEG) recordings of epilepsy patients, correlate with an enhancement or disruption of verbal episodic memory encoding. Methods: We defined ripple and spike events in depth iEEG recordings during list learning in 107 patients with focal epilepsy. We used logistic regression models (LRMs) to investigate the relationship between the occurrence of ripple and spike events during word presentation and the odds of successful word recall following a distractor epoch, and included the seizure onset zone (SOZ) as a covariate in the LRMs. Results: We detected events during 58,312 word presentation trials from 7,630 unique electrode sites. The probability of ripple on spike (RonS) events was increased in the seizure onset zone (SOZ, p<0.04). In the left temporal neocortex RonS events during word presentation corresponded with a decrease in the odds ratio (OR) of successful recall, however this effect only met significance in the SOZ (OR of word recall 0.71, 95% CI: 0.59-0.85, n=158 events, adaptive Hochberg p<0.01). Ripple on oscillation events (RonO) that occurred in the left temporal neocortex non-SOZ also correlated with decreased odds of successful recall (OR 0.52, 95% CI: 0.34-0.80, n=140, adaptive Hochberg , p<0.01). Spikes and RonS that occurred during word presentation in the left middle temporal gyrus during word presentation correlated with the most significant decrease in the odds of successful recall, irrespective of the location of the SOZ (adaptive Hochberg, p<0.01). Conclusion: Ripples and spikes generated in left temporal neocortex are associated with impaired verbal episodic memory encoding