7,431 research outputs found
Protecting superconducting qubits from external sources of loss and heat
We characterize a superconducting qubit before and after embedding it along
with its package in an absorptive medium. We observe a drastic improvement in
the effective qubit temperature and over a tenfold improvement in the
relaxation time up to 5.7 s. Our results suggest the presence of external
radiation inside the cryogenic apparatus can be a limiting factor for both
qubit initialization and coherence. We infer from simple calculations that
relaxation is not limited by thermal photons in the sample prior to embedding,
but by dissipation arising from quasiparticle generation.Comment: 3 figure
Entanglement of two superconducting qubits in a waveguide cavity via monochromatic two-photon excitation
We report a system where fixed interactions between non-computational levels
make bright the otherwise forbidden two-photon 00 --> 11 transition. The system
is formed by hand selection and assembly of two discrete component
transmon-style superconducting qubits inside a rectangular microwave cavity.
The application of a monochromatic drive tuned to this transition induces
two-photon Rabi-like oscillations between the ground and doubly-excited states
via the Bell basis. The system therefore allows all-microwave two-qubit
universal control with the same techniques and hardware required for single
qubit control. We report Ramsey-like and spin echo sequences with the generated
Bell states, and measure a two-qubit gate fidelity of 90% (unconstrained) and
86% (maximum likelihood estimator).Comment: 5 pages, 4 figures. V2: add supplemental material about the
Schrieffer-Wolff transformatio
A simple all-microwave entangling gate for fixed-frequency superconducting qubits
We demonstrate an all-microwave two-qubit gate on superconducting qubits
which are fixed in frequency at optimal bias points. The gate requires no
additional subcircuitry and is tunable via the amplitude of microwave
irradiation on one qubit at the transition frequency of the other. We use the
gate to generate entangled states with a maximal extracted concurrence of 0.88
and quantum process tomography reveals a gate fidelity of 81%
Attosecond time-resolved photoelectron holography
Ultrafast strong-field physics provides insight into quantum phenomena that evolve on an attosecond time scale, the most fundamental of which is quantum tunneling. The tunneling process initiates a range of strong field phenomena such as high harmonic generation (HHG), laser-induced electron diffraction, double ionization and photoelectron holography—all evolving during a fraction of the optical cycle. Here we apply attosecond photoelectron holography as a method to resolve the temporal properties of the tunneling process. Adding a weak second harmonic (SH) field to a strong fundamental laser field enables us to reconstruct the ionization times of photoelectrons that play a role in the formation of a photoelectron hologram with attosecond precision. We decouple the contributions of the two arms of the hologram and resolve the subtle differences in their ionization times, separated by only a few tens of attoseconds
Isolation and characterization of microsatellite loci from two inbreeding bark beetle species (Coccotrypes)
We developed 14 microsatellite markers in Coccotrypes carpophagus and 14 in C. dactyliperda.
These loci will be used for studying genetic structure and the level of inbreeding in
populations in the Canary Islands and Madeira. As a result of long-term inbreeding,
genetic variability is relatively low in these bark beetle species. We found one to five alleles
per locus in 29 C. carpophagus and 41 C. dactyliperda from various localities. Eleven of the
markers developed for C. carpophagus amplified in C. dactyliperda and seven of the markers
developed for C. dactyliperda amplified in C. carpophagus
Actief randenbeheer Drenthe lijkt effect te hebben
Via monitoring inzicht krijgen in het effect van actief randenbeheer op de oppervlaktewaterkwaliteit en de biodiversiteit in het landelijk gebied en op de inpasbaarheid op de agrarische bedrijven in een bepaald gebied. Dat was het doel van het pilotprogramma ‘Actief Randenbeheer Drenthe’: een initiatief van de Provincie Drenthe, LTO-Noord en de waterschappen Hunze en Aa’s en Velt en Vecht, in het zuidoostelijk deel van Drenthe. Uitvoerende partijen zijn Royal Haskoning, Praktijkonderzoek Plant & Omgeving van Wageningen UR en enkele agrarische bedrijven. Het programma begon in januari 2006 en is in november 2008 afgesloten. De totale duur van de meetperiode bedroeg 27 maande
Interaction of eukaryotic translation initiation factor 4G with the nuclear cap-binding complex provides a link between nuclear and cytoplasmic functions of the m7 guanosine cap
In eukaryotes the majority of mRNAs have an m7G cap that is added cotranscriptionally and that plays an important role in many aspects of mRNA metabolism. The nuclear cap-binding complex (CBC; consisting of CBP20 and CBP80) mediates the stimulatory functions of the cap in pre-mRNA splicing, 3' end formation, and U snRNA export. As little is known about how nuclear CBC mediates the effects of the cap in higher eukaryotes, we have characterized proteins that interact with CBC in HeLa cell nuclear extracts as potential mediators of its function. Using cross-linking and coimmunoprecipitation, we show that eukaryotic translation initiation factor 4G (eIF4G), in addition to its function in the cytoplasm, is a nuclear CBC-interacting protein. We demonstrate that eIF4G interacts with CBC in vitro and that, in addition to its cytoplasmic localization, there is a significant nuclear pool of eIF4G in mammalian cells in vivo. Immunoprecipitation experiments suggest that, in contrast to the cytoplasmic pool, much of the nuclear eIF4G is not associated with eIF4E (translation cap binding protein of eIF4F) but is associated with CBC. While eIF4G stably associates with spliceosomes in vitro and shows close association with spliceosomal snRNPs and splicing factors in vivo, depletion studies show that it does not participate directly in the splicing reaction. Taken together the data indicate that nuclear eIF4G may be recruited to pre-mRNAs via its interaction with CBC and accompanies the mRNA to the cytoplasm, facilitating the switching of CBC for eIF4F. This may provide a mechanism to couple nuclear and cytoplasmic functions of the mRNA cap structure
Complete universal quantum gate set approaching fault-tolerant thresholds with superconducting qubits
We use quantum process tomography to characterize a full universal set of
all-microwave gates on two superconducting single-frequency single-junction
transmon qubits. All extracted gate fidelities, including those for Clifford
group generators, single-qubit pi/4 and pi/8 rotations, and a two-qubit
controlled-NOT, exceed 95% (98%), without (with) accounting for state
preparation and measurement errors. Furthermore, we introduce a process map
representation in the Pauli basis which is visually efficient and informative.
This high-fidelity gate set serves as another critical building block towards
scalable architectures of superconducting qubits for error correction schemes.Comment: 4 figures, 2 tables plus supplementary materia
The intestinal expulsion of the roundworm Ascaris suum is associated with eosinophils, intra-epithelial T cells and decreased intestinal transit time
Ascaris lumbricoides remains the most common endoparasite in humans, yet there is still very little information available about the immunological principles of protection, especially those directed against larval stages. Due to the natural host-parasite relationship, pigs infected with A. suum make an excellent model to study the mechanisms of protection against this nematode. In pigs, a self-cure reaction eliminates most larvae from the small intestine between 14 and 21 days post infection. In this study, we investigated the mucosal immune response leading to the expulsion of A. suum and the contribution of the hepato-tracheal migration. Self-cure was independent of previous passage through the liver or lungs, as infection with lung stage larvae did not impair self-cure. When animals were infected with 14-day-old intestinal larvae, the larvae were being driven distally in the small intestine around 7 days post infection but by 18 days post infection they re-inhabited the proximal part of the small intestine, indicating that more developed larvae can counter the expulsion mechanism. Self-cure was consistently associated with eosinophilia and intra-epithelial T cells in the jejunum. Furthermore, we identified increased gut movement as a possible mechanism of self-cure as the small intestinal transit time was markedly decreased at the time of expulsion of the worms. Taken together, these results shed new light on the mechanisms of self-cure that occur during A. suum infections
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