429 research outputs found

    Exact Results of the 1D 1/r21/r^2 Supersymmetric t-J Model without Translational Invariance

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    In this work, we continue the study of the supersymmetric t-J model with 1/r^2 hopping and exchange without translational invariance. A set of Jastrow wavefunctions are obtained for the system, with eigenenergies explicitly calculated. The ground state of the t-J model is included in this set of wavefunctions. The spectrum of this t-J model consists of equal-distant energy levels which are highly degenerate.Comment: 14 pages, Late

    Measurement of Mass and Width of the W Boson at LEP

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    We report on measurements of the mass and total decay width of the W boson with the L3 detector at LEP. W-pair events produced in e+e\mathrm{e^+e^-} interactions between 161 GeV and 183 GeV centre-of-mass energy are selected in a data sample corresponding to a total luminosity of 76.7 pb1^{-1}. Combining all final states in W-pair production, the mass and total decay width of the W boson are determined to be MW=80.61±0.15\mathrm{M_W}=80.61\pm0.15 GeV and ΓW=1.97±0.38\Gamma_{\mathrm{W}}=1.97\pm0.38 GeV, respectively

    Prognostic and therapeutic significance of carbohydrate antigen 19-9 as tumor marker in patients with pancreatic cancer

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    In pancreatic cancer ( PC) accurate determination of treatment response by imaging often remains difficult. Various efforts have been undertaken to investigate new factors which may serve as more appropriate surrogate parameters of treatment efficacy. This review focuses on the role of carbohydrate antigen 19- 9 ( CA 19- 9) as a prognostic tumor marker in PC and summarizes its contribution to monitoring treatment efficacy. We undertook a Medline/ PubMed literature search to identify relevant trials that had analyzed the prognostic impact of CA 19- 9 in patients treated with surgery, chemoradiotherapy and chemotherapy for PC. Additionally, relevant abstract publications from scientific meetings were included. In advanced PC, pretreatment CA 19- 9 levels have a prognostic impact regarding overall survival. Also a CA 19- 9 decline under chemotherapy can provide prognostic information for median survival. A 20% reduction of CA 19- 9 baseline levels within the first 8 weeks of chemotherapy appears to be sufficient to define a prognostic relevant subgroup of patients ('CA 19- 9 responder'). It still remains to be defined whether the CA 19- 9 response is a more reliable method for evaluating treatment efficacy compared to conventional imaging. Copyright (c) 2006 S. Karger AG, Basel

    Extended 2D myotube culture recapitulates postnatal fibre type plasticity

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    Background: The traditional problems of performing skeletal muscle cell cultures derived from mammalian or avian species are limited myotube differentiation, and transient myotube persistence which greatly restricts the ability of myotubes to undergo phenotypic maturation. We report here on a major technical breakthrough in the establishment of a simple and effective method of extended porcine myotube cultures (beyond 50 days) in two-dimension (2D) that recapitulates key features of postnatal fibre types. Results: Primary porcine muscle satellite cells (myoblasts) were isolated from the longissimus dorsi of 4 to 6 weeks old pigs for 2D cultures to optimise myotube formation, improve surface adherence and characterise myotube maturation. Over 95 % of isolated cells were myoblasts as evidenced by the expression of Pax3 and Pax7. Our relatively simple approach, based on modifications of existing surface coating reagents (Maxgel), and of proliferation and differentiation (Ultroser G) media, typically achieved by 5 days of differentiation fusion index of around 80 % manifested in an abundance of discrete myosin heavy chain (MyHC) slow and fast myotubes. There was little deterioration in myotube viability over 50 days, and the efficiency of myotube formation was maintained over seven myoblast passages. Regular spontaneous contractions of myotubes were frequently observed throughout culture. Myotubes in extended cultures were able to undergo phenotypic adaptation in response to different culture media, including the adoption of a dominant postnatal phenotype of fast-glycolytic MyHC 2x and 2b expression by about day 20 of differentiation. Furthermore, fast-glycolytic myotubes coincided with enhanced expression of the putative porcine long intergenic non-coding RNA (linc-MYH), which has recently been shown to be a key coordinator of MyHC 2b expression in vivo. Conclusions: Our revised culture protocol allows the efficient differentiation and fusion of porcine myoblasts into myotubes and their prolonged adherence to the culture surface. Furthermore, we are able to recapitulate in 2D the maturation process of myotubes to resemble postnatal fibre types which represent a major technical advance in opening access to the in vitro study of coordinated postnatal muscle gene expression

    Search for charged Higgs bosons in e+ee^+ e^- collisions at centre-of-mass energies between 130 and 183 GeV

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    A search for pair-produced charged Higgs bosons is performed with the L3 detector at LEP using data collected at centre-of-mass energies from \mbox{130 to 183 \GeV{}}, corresponding to an integrated luminosity of 88.3 \pb. The Higgs decays into a charm and a strange quark or into a tau lepton and its associated neutrino are considered. The observed candidates are consistent with the expectations from Standard Model background processes. A lower limit of 57.5 \GeV{} on the charged Higgs mass is derived at 95\% CL, independent of the decay branching ratio \mathrm{Br(H^\pm\ra \tau\nu)}

    Study of Neutral-Current Four-Fermion and ZZ Production in e+ee^+ e^- Collisions at s\sqrt{s}= 183 GeV

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    Study of Neutral--Current Four--Fermion and ZZ \\ Production in e+e\rm e^+ e^- Collisions at s=\rm \sqrt{s}= 183 GeV A study of neutral--current four--fermion processes is performed using a data sample corresponding to 55.3~pb1^{-1} of integrated luminosity collected by the L3 detector at LEP at an average centre--of--mass energy of 183~\GeV. The neutral--current four--fermion cross sections for final states with a pair of charged leptons plus jets and with four charged leptons are measured to be consistent with the Standard Model predictions. Events with fermion pair masses close to the Z boson mass are selected in all observable final states and the ZZ production cross section is measured to be %\begin{center} σZZ=0.300.160.03+0.22+0.07pb,\rm \sigma_{ZZ} = 0.30 ^{+0.22\,\,+0.07}_{-0.16\,\,-0.03}\,\mathrm{pb}, %\end{center} in agreement with the Standard Model expectation. No evidence for the existence of anomalous triple gauge boson ZZZ and ZZγ\gamma couplings is found and limits on these couplings are set

    Heavy Quarkonium Production in Z Decays

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    We report measurements of the inclusive production of heavy quarkonium states in Z\mathrm {Z} decays based on the analysis of 3.6 million hadronic events collected by the L3 detector at LEP. The measurement of inclusive J production and an improved 95%95\% confidence level upper limit on Υ\Upsilon production are presented. In addition, two independent measurements of the ratio, fpf_{\mathrm{p}}, of prompt J mesons to those from B decay are made using two different isolation cuts to separate prompt J mesons from J mesons produced in the decays of b hadrons. The results are: % \begin{eqnarray} \mathrm{Br}(\mathrm{Z} \rightarrow \mathrm{J} + \mathrm{X}) & = & (3.21 \pm 0.21 \; \mathrm{(stat.)} \; ^{+ 0.19}_{- 0.28} \; \mathrm{(sys.)} ) \times 10^{-3} \; , \nonumber \\ \mathrm{Br}(\mathrm {Z} \rightarrow \Upsilon(\mathrm{1S} + X) & < & 4.4 \times 10^{-5} \; , \nonumber \\ %% f_{\mathrm{p}} & = & (7.1 \pm 2.1 \; \mathrm{(stat.)} \; \pm 1.2 \; \mathrm{(sys.)} \; ^{+1.5}_{-0.8} \;\mathrm{(theo.)} ) \times 10^{-2} \; . \nonumbe

    Measurement of the Michel Parameters and the Average τ\tau-Neutrino Helicity from τ\tau Decays at LEP

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    Four of the Michel parameters and the average tau-neutrino helicity have been measured by analysing tau decay spectra in 147 \pb ~of data collected by the L3 detector. The decays \tte, ~\ttm, ~\ttp, ~\ttr ~and their charge conjugates were considered. The results: ρ=0.762±0.035\rho = 0.762 \pm 0.035, η=0.27±0.14\eta = 0.27 \pm 0.14, ξ=0.70±0.16\xi = 0.70 \pm 0.16, ξδ=0.70±0.11\xi\delta = 0.70 \pm0.11 and ξh=1.032±0.031\xi_{h} = -1.032 \pm 0.031 are consistent with a V-A structure for the weak charged current and lepton universality

    Measurement of the Effective Weak Mixing Angle by Jet-Charge Asymmetry in Hadronic Decays of the Z Boson

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    The coupling of the Z boson to quarks is studied in a sample of about 3.5 million hadronic Z decays collected by the L3 experiment at LEP from 1991 to 1995. The forward-backward quark charge asymmet ry is measured by means of a jet charge technique. From the measured asymmetries, the effective weak mixing angle is determined to be \begin{center} $\STE = 0.2327 \pm 0.0012(\mbox{\emph{stat.}} ) \pm 0.0013(\mbox{\emph{syst.}
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