806 research outputs found
Spin relaxation in mesoscopic superconducting Al wires
We studied the diffusion and the relaxation of the polarized quasiparticle
spins in superconductors. To that end, quasiparticles of polarized spins were
injected through an interface of a mesoscopic superconducting Al wire in
proximity contact with an overlaid ferromagnetic Co wire in the single-domain
state. The superconductivity was observed to be suppressed near the
spin-injecting interface, as evidenced by the occurrence of a finite voltage
for a bias current below the onset of the superconducting transition. The spin
diffusion length, estimated from finite voltages over a certain length of Al
wire near the interface, was almost temperature independent in the temperature
range sufficiently below the superconducting transition but grew as the
transition temperature was approached. This temperature dependence suggests
that the relaxation of the spin polarization in the superconducting state is
governed by the condensation of quasiparticles to the paired state. The spin
relaxation in the superconducting state turned out to be more effective than in
the normal state.Comment: 9 pages, 8 figure
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Microbiota-Produced N-Formyl Peptide fMLF Promotes Obesity-Induced Glucose Intolerance.
The composition of the gastrointestinal microbiota and associated metabolites changes dramatically with diet and the development of obesity. Although many correlations have been described, specific mechanistic links between these changes and glucose homeostasis remain to be defined. Here we show that blood and intestinal levels of the microbiota-produced N-formyl peptide, formyl-methionyl-leucyl-phenylalanine, are elevated in high-fat diet-induced obese mice. Genetic or pharmacological inhibition of the N-formyl peptide receptor Fpr1 leads to increased insulin levels and improved glucose tolerance, dependent upon glucagon-like peptide 1. Obese Fpr1 knockout mice also display an altered microbiome, exemplifying the dynamic relationship between host metabolism and microbiota. Overall, we describe a new mechanism by which the gut microbiota can modulate glucose metabolism, providing a potential approach for the treatment of metabolic disease
The Chemical Compositions of Very Metal-Poor Stars HD 122563 and HD 140283; A View From the Infrared
From high resolution (R = 45,000), high signal-to-noise (S/N > 400) spectra
gathered with the Immersion Grating Infrared Spectrograph (IGRINS) in the H and
K photometric bands, we have derived elemental abundances of two bright,
well-known metal-poor halo stars: the red giant HD 122563 and the subgiant HD
140283. Since these stars have metallicities approaching [Fe/H] = -3, their
absorption features are generally very weak. Neutral-species lines of Mg, Si, S
and Ca are detectable, as well as those of the light odd-Z elements Na and Al.
The derived IR-based abundances agree with those obtained from
optical-wavelength spectra. For Mg and Si the abundances from the infrared
transitions are improvements to those derived from shorter wavelength data.
Many useful OH and CO lines can be detected in the IGRINS HD 122563 spectrum,
from which derived O and C abundances are consistent to those obtained from the
traditional [O I] and CH features. IGRINS high resolutions H- and K-band
spectroscopy offers promising ways to determine more reliable abundances for
additional metal-poor stars whose optical features are either not detectable,
or too weak, or are based on lines with analytical difficulties.Comment: Accepted for publication in ApJ (28 pages, 4 tables, 6 figures
Critical point network for drainage between rough surfaces
In this paper, we present a network method for computing two-phase flows between two rough surfaces with significant contact areas. Low-capillary number drainage is investigated here since one-phase flows have been previously investigated in other contributions. An invasion percolation algorithm is presented for modeling slow displacement of a wetting fluid by a non wetting one between two rough surfaces. Short-correlated Gaussian process is used to model random rough surfaces.The algorithm is based on a network description of the fracture aperture field. The network is constructed from the identification of critical points (saddles and maxima) of the aperture field. The invasion potential is determined from examining drainage process in a flat mini-channel. A direct comparison between numerical prediction and experimental visualizations on an identical geometry has been performed for one realization of an artificial fracture with a moderate fractional contact area of about 0.3. A good agreement is found between predictions and observations
Motivations and Conflicts in Prison Medical Contracting
State correctional departments are responsible for all medical care incarcerated individuals require. Many systems outsource their medical
State correctional departments are responsible for all medical care incarcerated individuals require. Many systems outsource their medical program. Literature indicates that many of these contracts experience significant issues that negatively impact state resources, including both personnel and money.
This dissertation explores the relationship between prison administrators\u27 motivations and the structure, outcomes, efficiencies, and partner conflicts that arise in the contractual process. Using a framework developed from Incomplete Contract Theory, Contracts as Reference Points Theory and the concept of “essential tension,” this dissertation hypothesizes that the administrator’s motivation will impact the likelihood of success, contract efficiencies and partnership conflicts in case of prison medical contracts.
The mixed-method study employs both quantitative and qualitative research methods. Study results indicate a preliminary finding that public administrators’ motivation does correlates with predictable differences in contract design and contract outcomes. States motivated to improve cost control, are more likely to allow the vendor space to manage financial resources but restrict the ability to determine efficient ways to achieve quality, which seems associated with problems in outputs, efficiencies and conflicts.
These findings have implications for contracting and the use of contracts by public administrators. The results suggest that contract completeness is more nuanced than a contract being complete or not complete on the whole. Additionally, the application of completeness and incompleteness in different sections can be an intentional and strategic action on the part of the public administrator that could be used to enhance the usefulness of a complex contract.
. Literature indicates that many of these contracts experience significant issues that negatively impact state resources, including both personnel and money.
This dissertation explores the relationship between prison administrators\u27 motivations and the structure, outcomes, efficiencies, and partner conflicts that arise in the contractual process. Using a framework developed from Incomplete Contract Theory, Contracts as Reference Points Theory and the concept of “essential tension,” this dissertation hypothesizes that the administrator’s motivation will impact the likelihood of success, contract efficiencies and partnership conflicts in case of prison medical contracts.
The mixed-method study employs both quantitative and qualitative research methods. Study results indicate a preliminary finding that public administrators’ motivation does correlates with predictable differences in contract design and contract outcomes. States motivated to improve cost control, are more likely to allow the vendor space to manage financial resources but restrict the ability to determine efficient ways to achieve quality, which seems associated with problems in outputs, efficiencies and conflicts.
These findings have implications for contracting and the use of contracts by public administrators. The results suggest that contract completeness is more nuanced than a contract being complete or not complete on the whole. Additionally, the application of completeness and incompleteness in different sections can be an intentional and strategic action on the part of the public administrator that could be used to enhance the usefulness of a complex contract
Approximate Ginzburg-Landau solution for the regular flux-line lattice. Circular cell method
A variational model is proposed to describe the magnetic properties of
type-II superconductors in the entire field range between and
for any values of the Ginzburg-Landau parameter . The
hexagonal unit cell of the triangular flux-line lattice is replaced by a circle
of the same area, and the periodic solutions to the Ginzburg-Landau equations
within this cell are approximated by rotationally symmetric solutions. The
Ginzburg-Landau equations are solved by a trial function for the order
parameter. The calculated spatial distributions of the order parameter and the
magnetic field are compared with the corresponding distributions obtained by
numerical solution of the Ginzburg-Landau equations. The comparison reveals
good agreement with an accuracy of a few percent for all values
exceeding . The model can be extended to anisotropic
superconductors when the vortices are directed along one of the principal axes.
The reversible magnetization curve is calculated and an analytical formula for
the magnetization is proposed. At low fields, the theory reduces to the London
approach at , provided that the exact value of is used.
At high fields, our model reproduces the main features of the well-known
Abrikosov theory. The magnetic field dependences of the reversible
magnetization found numerically and by our variational method practically
coincide. The model also refines the limits of some approximations which have
been widely used. The calculated magnetization curves are in a good agreement
with experimental data on high-T superconductors.Comment: 8 pages, RevTex, 6 figures, submitted to Phys. Rev.
Mark correlations: relating physical properties to spatial distributions
Mark correlations provide a systematic approach to look at objects both
distributed in space and bearing intrinsic information, for instance on
physical properties. The interplay of the objects' properties (marks) with the
spatial clustering is of vivid interest for many applications; are, e.g.,
galaxies with high luminosities more strongly clustered than dim ones? Do
neighbored pores in a sandstone have similar sizes? How does the shape of
impact craters on a planet depend on the geological surface properties? In this
article, we give an introduction into the appropriate mathematical framework to
deal with such questions, i.e. the theory of marked point processes. After
having clarified the notion of segregation effects, we define universal test
quantities applicable to realizations of a marked point processes. We show
their power using concrete data sets in analyzing the luminosity-dependence of
the galaxy clustering, the alignment of dark matter halos in gravitational
-body simulations, the morphology- and diameter-dependence of the Martian
crater distribution and the size correlations of pores in sandstone. In order
to understand our data in more detail, we discuss the Boolean depletion model,
the random field model and the Cox random field model. The first model
describes depletion effects in the distribution of Martian craters and pores in
sandstone, whereas the last one accounts at least qualitatively for the
observed luminosity-dependence of the galaxy clustering.Comment: 35 pages, 12 figures. to be published in Lecture Notes of Physics,
second Wuppertal conference "Spatial statistics and statistical physics
Human H5N1 influenza infections in Cambodia 2005-2011: case series and cost-of-illness.
BACKGROUND: Southeast Asia has been identified as a potential epicentre of emerging diseases with pandemic capacity, including highly pathogenic influenza. Cambodia in particular has the potential for high rates of avoidable deaths from pandemic influenza due to large gaps in health system resources. This study seeks to better understand the course and cost-of-illness for cases of highly pathogenic avian influenza in Cambodia. METHODS: We studied the 18 laboratory-confirmed cases of avian influenza subtype H5N1 identified in Cambodia between January 2005 and August 2011. Medical records for all patients were reviewed to extract information on patient characteristics, travel to hospital, time to admission, diagnostic testing, treatment and disease outcomes. Further data related to costs was collected through interviews with key informants at district and provincial hospitals, the Ministry of Health and non-governmental organisations. An ingredient-based approach was used to estimate the total economic cost for each study patient. Costing was conducted from a societal perspective and included both financial and opportunity costs to the patient or carer. Sensitivity analysis was undertaken to evaluate potential change or variation in the cost-of-illness. RESULTS: Of the 18 patients studied, 11 (61%) were under the age of 18 years. The majority of patients (16, 89%) died, eight (44%) within 24 hours of hospital admission. There was an average delay of seven days between symptom onset and hospitalisation with patients travelling an average of 148 kilometres (8-476 km) to the admitting hospital. Five patients were treated with oseltamivir of whom two received the recommended dose. For the 16 patients who received all their treatment in Cambodia the average per patient cost of H5N1 influenza illness was US45 per patient (15.0%) of total economic cost. CONCLUSION: Cases of avian influenza in Cambodia were characterised by delays in hospitalisation, deficiencies in some aspects of treatment and a high fatality rate. The costs associated with medical care, particularly diagnostic testing and pharmaceutical therapy, were major contributors to the relatively high cost-of-illness
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