3,746 research outputs found
The effects of water impinging on thermally controlled surfaces under space conditions
Analysis of monochromatic reflectance changes due to impinging water spray from sharp-edge nozzles on thermally-controlled paints under space condition
Potential Economic Consequences of Local Nonconformity to Regional Land Use and Transportation Plans Using a Spatial Economic Model
To achieve the greenhouse gas (GHG) reduction targets that are required by California’s global warming legislation (AB32), the state of California has determined that recent growth trends in vehicle miles traveled (VMT) must be curtailed. In recognition of this, Senate Bill 375 (SB375) requires regional governments to develop land use and transportation plans or Sustainable Community Strategies (SCSs) that will achieve regional GHG targets largely though reduced VMT. Although the bill requires such a plan, it does not require local governments to adopt general plans that conform to this plan. In California, it is local, not regional, governments that have authority over land development decisions. Instead, SB375 relies on democratic participatory processes and relatively modest financial and regulatory incentives for SCS implementation. As a result, it is quite possible that some local governments within a region may decide not to conform to their SCS. In this study, a spatial economic model (PECAS) is applied in the Sacramento region (California, U.S.) to understand what the economic and equity consequences might be to jurisdictions that do and do not implement SCS land use plans in a region. An understanding of these consequences provides insight into jurisdictions’ motivations for compliance and thus, strategies for more effective implementation of SB375
Signatures of the collapse and revival of a spin Schr\"{o}dinger cat state in a continuously monitored field mode
We study the effects of continuous measurement of the field mode during the
collapse and revival of spin Schr\"{o}dinger cat states in the Tavis-Cummings
model of N qubits (two-level quantum systems) coupled to a field mode. We show
that a compromise between relatively weak and relatively strong continuous
measurement will not completely destroy the collapse and revival dynamics while
still providing enough signal-to-noise resolution to identify the signatures of
the process in the measurement record. This type of measurement would in
principle allow the verification of the occurrence of the collapse and revival
of a spin Schr\"{o}dinger cat state.Comment: 5 pages, 2 figure
Cool for Cats
The iconic Schr\"odinger's cat state describes a system that may be in a
superposition of two macroscopically distinct states, for example two clearly
separated oscillator coherent states. Quite apart from their role in
understanding the quantum classical boundary, such states have been suggested
as offering a quantum advantage for quantum metrology, quantum communication
and quantum computation. As is well known these applications have to face the
difficulty that the irreversible interaction with an environment causes the
superposition to rapidly evolve to a mixture of the component states in the
case that the environment is not monitored. Here we show that by engineering
the interaction with the environment there exists a large class of systems that
can evolve irreversibly to a cat state. To be precise we show that it is
possible to engineer an irreversible process so that the steady state is close
to a pure Schr\"odinger's cat state by using double well systems and an
environment comprising two-photon (or phonon) absorbers. We also show that it
should be possible to prolong the lifetime of a Schr\"odinger's cat state
exposed to the destructive effects of a conventional single-photon decohering
environment. Our protocol should make it easier to prepare and maintain
Schr\"odinger cat states which would be useful in applications of quantum
metrology and information processing as well as being of interest to those
probing the quantum to classical transition.Comment: 10 pages, 7 figures. Significantly updated version with supplementary
informatio
Quantitative measurement of permeabilization of living cells by terahertz attenuated total reflection
International audienceUsing Attenuated Total Reflection imaging technique in the terahertz domain, we demonstrate non-invasive, non-staining real time measurements of cytoplasm leakage during permeabilization of epithelial cells by saponin. The terahertz signal is mostly sensitive to the intracellular protein concentration in the cells, in a very good agreement with standard bicinchoninic acid protein measurements. It opens the way to in situ real time dynamics of protein content and permeabilization in live cells
Analytical evaluation of the X-ray scattering contribution to imaging degradation in grazing-incidence X-ray telescopes
The focusing performance of X-ray optics (conveniently expressed in terms of
HEW, Half Energy Width) strongly depend on both mirrors deformations and photon
scattering caused by the microroughness of reflecting surfaces. In particular,
the contribution of X-ray Scattering (XRS) to the HEW of the optic is usually
an increasing function H(E) of the photon energy E. Therefore, in future hard
X-ray imaging telescopes of the future (SIMBOL-X, NeXT, Constellation-X, XEUS),
the X-ray scattering could be the dominant problem since they will operate also
in the hard X-ray band (i.e. beyond 10 keV). [...]
Several methods were proposed in the past years to estimate the scattering
contribution to the HEW, dealing with the surface microroughness expressed in
terms of its Power Spectral Density (PSD), on the basis of the well-established
theory of X-ray scattering from rough surfaces. We faced that problem on the
basis on the same theory, but we tried a new approach: the direct, analytical
translation of a given surface roughness PSD into a H(E) trend, and - vice
versa - the direct translation of a H(E) requirement into a surface PSD. This
PSD represents the maximum tolerable microroughness level in order to meet the
H(E) requirement in the energy band of a given X-ray telescope.
We have thereby found a new, analytical and widely applicable formalism to
compute the XRS contribution to the HEW from the surface PSD, provided that the
PSD had been measured in a wide range of spatial frequencies. The inverse
problem was also solved, allowing the immediate evaluation of the mirror
surface PSD from a measured function H(E). The same formalism allows
establishing the maximum allowed PSD of the mirror in order to fulfill a given
H(E) requirement. [...]Comment: 10 pages, 6 figures, published in Astronomy & Astrophysics, sect.
"Astronomical Instrumentation". In this version, a typo in two equations has
been corrected. After the correction, the other results, formulae and
conclusions in the paper remain unchange
p63 is required beside p53 for PERP-mediated apoptosis in uveal melanoma
Background:
PERP (p53 apoptosis effector related to PMP-22), a transcriptional target of p53, is downregulated and contributes to the impairment of apoptosis in uveal melanoma (UM). Intriguingly, PERP is not induced in UM despite functional p53. p63, located on chromosome 3, which is characteristically altered in high-risk UM, can transactivate PERP. Here, we determine the functional role of p63 expression in the initiation of p53/PERP-mediated apoptosis in UM.
Methods:
PERP expression was monitored by quantitative PCR (qPCR) and immunoblotting in UM cell lines treated with DNA-damaging agents. The functional role of p63 was assessed by transient expression of p63-turbo GFP (p63-tGFP) in the apoptosis- resistant, 3q-deficient OCM-1 cells. Expression and localisation of p63, PERP and p53, and induction of apoptosis were characterised by qPCR, immunoblotting and live cell confocal microscopy.
Results:
PERP expression was significantly downregulated in all UM cell lines. DNA-damaging treatments failed to induce apoptosis and activate PERP in OCM-1 cells, which displayed non-functional levels of p63. Expression of p63-tGFP induced apoptosis with marked increase in PERP expression and associated p53 accumulation.
Conclusions:
Lack of p63 contributes to reduced PERP levels and impaired p53-mediated apoptosis in UM. p63 expression is required for PERP-mediated apoptosis in UM
Efficient optical quantum information processing
Quantum information offers the promise of being able to perform certain
communication and computation tasks that cannot be done with conventional
information technology (IT). Optical Quantum Information Processing (QIP) holds
particular appeal, since it offers the prospect of communicating and computing
with the same type of qubit. Linear optical techniques have been shown to be
scalable, but the corresponding quantum computing circuits need many auxiliary
resources. Here we present an alternative approach to optical QIP, based on the
use of weak cross-Kerr nonlinearities and homodyne measurements. We show how
this approach provides the fundamental building blocks for highly efficient
non-absorbing single photon number resolving detectors, two qubit parity
detectors, Bell state measurements and finally near deterministic control-not
(CNOT) gates. These are essential QIP devicesComment: Accepted to the Journal of optics B special issue on optical quantum
computation; References update
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