Robotic Resistance Treadmill Training Improves Locomotor Function in Children With Cerebral Palsy: A Randomized Controlled Pilot Study

Objective To determine whether applying controlled resistance forces to the legs during the swing phase of gait may improve the efficacy of treadmill training as compared with applying controlled assistance forces in children with cerebral palsy (CP). Design Randomized controlled study. Setting Research unit of a rehabilitation hospital. Participants Children with spastic CP (N=23; mean age, 10.6y; range, 6–14y; Gross Motor Function Classification System levels, I–IV). Interventions Participants were randomly assigned to receive controlled assistance (n=11) or resistance (n=12) loads applied to the legs at the ankle. Participants underwent robotic treadmill training 3 times a week for 6 weeks (18 sessions). A controlled swing assistance/resistance load was applied to both legs starting from the toe-off to mid-swing phase of gait during training. Main Outcome Measures Outcome measures consisted of overground walking speed, 6-minute walk distance, and Gross Motor Function Measure scores and were assessed pre and post 6 weeks of training and 8 weeks after the end of training. Results After 6 weeks of treadmill training in participants from the resistance training group, fast walking speed and 6-minute walk distance significantly improved (18% and 30% increases, respectively), and 6-minute walk distance was still significantly greater than that at baseline (35% increase) 8 weeks after the end of training. In contrast, overground gait speed and 6-minute walk distance had no significant changes after robotic assistance training. Conclusions The results of the present study indicated that robotic resistance treadmill training is more effective than assistance training in improving locomotor function in children with CP

Effects of SUSY-QCD in hadronic Higgs production at next-to-next-to-leading order

An estimate of the NNLO supersymmetric QCD effects for Higgs production at hadron colliders is given. Assuming an effective gluon-Higgs interaction, these corrections enter only in terms of process-independent, factorizable terms. We argue that the current knowledge of these terms up to NLO is sufficient to derive the NNLO hadronic cross section within the limitations of the standard theoretical uncertainties arising mainly from renormalization and factorization scale variations. The SUSY contributions are small with respect to the QCD effects, which means that the NNLO corrections to Higgs production are very similar in the Standard Model and the MSSM.Comment: LaTeX, 5 pages, 3 embedded PostScript figure

QCD Corrections to SUSY Higgs Production: The Role of Squark Loops

We calculate the two-loop QCD corrections to the production of the neutral supersymmetric Higgs bosons via the gluon fusion mechanism at hadron colliders, including the contributions of squark loops. To a good approximation, these additional contributions lead to the same QCD corrections as in the case where only top and bottom quark loops are taken into account. The QCD corrections are large and increase the Higgs production cross sections significantly.Comment: 5 pages, latex, 2 figure

Next-to-leading order jet distributions for Higgs boson production via weak-boson fusion

The weak-boson fusion process is expected to provide crucial information on Higgs boson couplings at the Large Hadron Collider at CERN. The achievable statistical accuracy demands comparison with next-to-leading order QCD calculations, which are presented here in the form of a fully flexible parton Monte Carlo program. QCD corrections are determined for jet distributions and are shown to be modest, of order 5 to 10% in most cases, but reaching 30% occasionally. Remaining scale uncertainties range from order 5% or less for distributions to below +-2% for the Higgs boson cross section in typical weak-boson fusion search regions.Comment: 19 pages, 8 figure

Determining the Structure of Higgs Couplings at the LHC

Higgs boson production via weak boson fusion at the CERN Large Hadron Collider has the capability to determine the dominant CP nature of a Higgs boson, via the tensor structure of its coupling to weak bosons. This information is contained in the azimuthal angle distribution of the two outgoing forward tagging jets. The technique is independent of both the Higgs boson mass and the observed decay channel.Comment: 5 pages, 4 figures, version accepted for publication in PR

Roots of the derivative of the Riemann zeta function and of characteristic polynomials

We investigate the horizontal distribution of zeros of the derivative of the Riemann zeta function and compare this to the radial distribution of zeros of the derivative of the characteristic polynomial of a random unitary matrix. Both cases show a surprising bimodal distribution which has yet to be explained. We show by example that the bimodality is a general phenomenon. For the unitary matrix case we prove a conjecture of Mezzadri concerning the leading order behavior, and we show that the same follows from the random matrix conjectures for the zeros of the zeta function.Comment: 24 pages, 6 figure

Exact Hybrid Covariance Thresholding for Joint Graphical Lasso

This paper considers the problem of estimating multiple related Gaussian graphical models from a $p$-dimensional dataset consisting of different classes. Our work is based upon the formulation of this problem as group graphical lasso. This paper proposes a novel hybrid covariance thresholding algorithm that can effectively identify zero entries in the precision matrices and split a large joint graphical lasso problem into small subproblems. Our hybrid covariance thresholding method is superior to existing uniform thresholding methods in that our method can split the precision matrix of each individual class using different partition schemes and thus split group graphical lasso into much smaller subproblems, each of which can be solved very fast. In addition, this paper establishes necessary and sufficient conditions for our hybrid covariance thresholding algorithm. The superior performance of our thresholding method is thoroughly analyzed and illustrated by a few experiments on simulated data and real gene expression data

Top quark associated production of topcolor pions at hadron colliders

We investigate the associated production of a neutral physical pion with top quarks in the context of topcolor assisted technicolor. We find that single-top associated production does not yield viable rates at either the Tevatron or LHC. tt-associated production at the Tevatron is suppressed relative to Standard Model ttH, but at the LHC is strongly enhanced and would allow for easy observation of the main decay channels to bottom quarks, and possible observation of the decay to gluons.Comment: 13 pages, 4 figures, submitted to PR

Higgs Physics: Theory

I review the theoretical aspects of the physics of Higgs bosons, focusing on the elements that are relevant for the production and detection at present hadron colliders. After briefly summarizing the basics of electroweak symmetry breaking in the Standard Model, I discuss Higgs production at the LHC and at the Tevatron, with some focus on the main production mechanism, the gluon-gluon fusion process, and summarize the main Higgs decay modes and the experimental detection channels. I then briefly survey the case of the minimal supersymmetric extension of the Standard Model. In a last section, I review the prospects for determining the fundamental properties of the Higgs particles once they have been experimentally observed.Comment: 21 pages, 15 figures. Talk given at the XXV International Symposium on Lepton Photon Interactions at High Energies (Lepton Photon 11), 22-27 August 2011, Mumbai, Indi