149 research outputs found
Short-term propofol sedation increases serum levels of parathyroid hormone independent of calcium levels in normal subjects
Cost of care associated with early sepsis (first 24-hours of ICU admission) in a United States medical center
Inter-Observer Agreement Among Medical Professionals in Critical Care of Neonates and Children
Economic Consequences of Artificial Intelligence and Labor Automation: Employment Recovery, Transformation of Labor Markets, and Dynamics of Social Structure in the Context of Digital Transformation
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Getting Ready for College: An Implementation and Early Impacts Study of Eight Texas Developmental Summer Bridge Programs
In 2007, the Texas Higher Education Coordinating Board (THECB) funded 22 colleges to establish developmental summer bridge programs. Aimed at providing an alternative to traditional developmental education, these programs involve intensive remedial instruction in math, reading, and/or writing and college preparation content for students entering college with low basic skills. In 2009, the National Center for Postsecondary Research (NCPR) launched an evaluation of eight developmental summer bridge programs in Texas (seven at community colleges and one at an open-admissions four-year university), the early findings of which are described in this report. Students who participated in the study were randomly assigned to the program group or the control group. Program group students participated in the developmental summer bridge programs, while control group students received colleges’ regular services. All developmental summer bridge programs had four common features: accelerated instruction in math, reading, and/or writing; academic support; a “college knowledge” component; and the opportunity for participants to receive a $400 stipend
Chitosan-Based Polyelectrolyte Complex in Combination with Allotropic Forms of Carbon as a Basis for Thin-Film Organic Electronics
Received: 30.05.2024. Revised: 11.06.2024. Accepted: 19.06.2024. Available online: 28.06.2024.Samples of a new polymer composite material based on a PEC doped with various allotropic forms of carbon were prepared.Based on the films studied, field-effect transistors were created and their output and transfer characteristics were measured.If a combination of both GO and SWCNT is incorporated into the nanocomposite, the mobility of carriers increases sharply.Using atomic force microscopy, scanning electron microscopy, cyclic voltammetry and electrochemical impedance spectroscopy, the morphology and mobility of charge carriers in composite films with a thickness of no more than 500 nm obtained on the basis of a polyelectrolyte complex of chitosan and chitosan succinamide with addition of particles of carbon materials were studied and estimated. The following carbon materials were used: single-walled carbon nanotubes, graphene oxide, and carbon-containing sorbents with different specific surfaces (Carboblack C and Carbopack). Moreover, the studied materials in the form of films were used as a transport layer in the structure of field-effect transistors. The output and transfer characteristics of the transistors obtained were measured. According to the measurement results, the mobility of charge carriers, μ, ranges from 0.341 to 1.123 cm2 V–1·s–1, depending on the type of carbon material added. The best result was demonstrated by films based on a composite containing simultaneously single-walled carbon nanotubes and graphene oxide (μ = 10.972 cm2 V–1·s–1).This work was supported by the Ministry of Science and Higher Education of the Russian Federation (scientific code FZWU-2023-0002) and by the Russian Science Foundation (Grant № 23-73-00119), https://rscf.ru/project/23-73-00119/
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Getting Ready for College: An Implementation and Early Impact Study of Eight Texas Developmental Summer Bridge Programs
Displayed on billboards and license plates alike, “College for All Texans” is the unofficial motto that is promoted statewide to encourage college readiness, participation, and success in Texas. Policymakers, educators, and business leaders agree that Texas must increase rates of college participation and success to preserve the economic vitality of the state and to secure the future well-being of Texas residents. To address the dynamic needs of the growing state population, Texas launched in 2000 an ambitious statewide strategic plan called called Closing the Gaps by 2015. One of the primary objectives of this plan is to increase enrollment and academic success in Texas colleges and universities. One component of the Closing the Gaps by 2015 initiative was the creation of developmental summer bridge programs — intensive summer experiences that offer eligible students remedial instruction in math, reading, and/or writing along with an introduction to college. Developmental summer bridge programs aim to reduce or eliminate the need for developmental courses so that more students are prepared for college-level courses in their first semester of college. Programs typically offer intensive, targeted coursework for four to five weeks over the summer, accompanied by tutoring, additional labs, and student support services. The integrated approach used in developmental summer bridge programs is thought to help ease students’ transition into college. But despite the increasing popularity of summer bridge programs across the country, little empirical research on their outcomes or impacts has been conducte
APACHE III outcome prediction in patients admitted to the intensive care unit after liver transplantation: a retrospective cohort study
<p>Abstract</p> <p>Background</p> <p>The Acute Physiology and Chronic Health Evaluation (APACHE) III prognostic system has not been previously validated in patients admitted to the intensive care unit (ICU) after orthotopic liver transplantation (OLT). We hypothesized that APACHE III would perform satisfactorily in patients after OLT</p> <p>Methods</p> <p>A retrospective cohort study was performed. Patients admitted to the ICU after OLT between July 1996 and May 2008 were identified. Data were abstracted from the institutional APACHE III and liver transplantation databases and individual patient medical records. Standardized mortality ratios (with 95% confidence intervals) were calculated by dividing the observed mortality rates by the rates predicted by APACHE III. The area under the receiver operating characteristic curve (AUC) and the Hosmer-Lemeshow C statistic were used to assess, respectively, discrimination and calibration of APACHE III.</p> <p>Results</p> <p>APACHE III data were available for 918 admissions after OLT. Mean (standard deviation [SD]) APACHE III (APIII) and Acute Physiology (APS) scores on the day of transplant were 60.5 (25.8) and 50.8 (23.6), respectively. Mean (SD) predicted ICU and hospital mortality rates were 7.3% (15.4) and 10.6% (18.9), respectively. The observed ICU and hospital mortality rates were 1.1% and 3.4%, respectively. The standardized ICU and hospital mortality ratios with their 95% C.I. were 0.15 (0.07 to 0.27) and 0.32 (0.22 to 0.45), respectively.</p> <p>There were statistically significant differences in APS, APIII, predicted ICU and predicted hospital mortality between survivors and non-survivors. In predicting mortality, the AUC of APACHE III prediction of hospital death was 0.65 (95% CI, 0.62 to 0.68). The Hosmer-Lemeshow C statistic was 5.288 with a p value of 0.871 (10 degrees of freedom).</p> <p>Conclusion</p> <p>APACHE III discriminates poorly between survivors and non-survivors of patients admitted to the ICU after OLT. Though APACHE III has been shown to be valid in heterogenous populations and in certain groups of patients with specific diagnoses, it should be used with caution – if used at all – in recipients of liver transplantation.</p
Hospital mortality is associated with ICU admission time
Previous studies have shown that patients admitted to the intensive care unit (ICU) after "office hours" are more likely to die. However these results have been challenged by numerous other studies. We therefore analysed this possible relationship between ICU admission time and in-hospital mortality in The Netherlands. This article relates time of ICU admission to hospital mortality for all patients who were included in the Dutch national ICU registry (National Intensive Care Evaluation, NICE) from 2002 to 2008. We defined office hours as 08:00-22:00 hours during weekdays and 09:00-18:00 hours during weekend days. The weekend was defined as from Saturday 00:00 hours until Sunday 24:00 hours. We corrected hospital mortality for illness severity at admission using Acute Physiology and Chronic Health Evaluation II (APACHE II) score, reason for admission, admission type, age and gender. A total of 149,894 patients were included in this analysis. The relative risk (RR) for mortality outside office hours was 1.059 (1.031-1.088). Mortality varied with time but was consistently higher than expected during "off hours" and lower during office hours. There was no significant difference in mortality between different weekdays of Monday to Thursday, but mortality increased slightly on Friday (RR 1.046; 1.001-1.092). During the weekend the RR was 1.103 (1.071-1.136) in comparison with the rest of the week. Hospital mortality in The Netherlands appears to be increased outside office hours and during the weekends, even when corrected for illness severity at admission. However, incomplete adjustment for certain confounders might still play an important role. Further research is needed to fully explain this differenc
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