Pan African strategy for the progressive control of peste des petits ruminants (Pan African ppr strategy)

Peste des petits ruminants (PPR) is a major constraint to the livelihoods and food security of small scale farmers. The epidemiology and biology of PPR virus has much in common with rinderpest virus (RP), an agent that has been globally eradicated. This document presents a strategy for the progressive control of PPR that builds upon the lessons learnt from rinderpest eradication. Progressive control relies upon a modular approach that consists of a series of self-sufficient phases each with its own set of sustainable results. Key intermediate results will be proven business models for sustainable PPR control service delivery and enhanced capacity of animal health institutions to target control services to critical control points. The program will foster an adaptive management approach that integrates learning approaches to drive animal health institutional innovation. The coordinated drive towards long term animal health goals will add value to on-going investments in infectious disease control

Impact of Scottish vocational qualifications on residential child care : have they fulfilled the promise?

This article will present findings from a doctoral study exploring the impact of 'SVQ Care: Promoting Independence (level III)' within children's homes. The study focuses on the extent to which SVQs enhance practice and their function within a 'learning society'. A total of 30 staff were selected from seven children's homes in two different local authority social work departments in Scotland. Each member of staff was interviewed on four separate occasions over a period of 9 months. Interviews were structured using a combination of repertory grids and questions. Particular focus was given to the assessment process, the extent to which SVQs enhance practice and the learning experiences of staff. The findings suggest that there are considerable deficiencies both in terms of the SVQ format and the way in which children's homes are structured for the assessment of competence. Rather than address the history of failure within residential care, it appears that SVQs have enabled the status quo to be maintained whilst creating an 'illusion' of change within a learning society

Toward a conceptual framework of emotional relationship marketing: an examination of two UK political parties

The purpose of this paper is to review the notion of branding and evaluate its applicability to political parties. As ideological politics is in decline, branding may provide a consistent narrative where voters feel a sense of warmth and belonging. The paper aims to build an understanding of the complexity of building a political brand where a combination of image, logo, leadership, and values can all contribute to a compelling brand narrative. It investigates how competing positive and negative messages attempt to build and distort the brand identity. A critical review of bran ding, relationship marketing, and political science literature articulates the conceptual development of branding and its applicability to political parties. The success or failure of negative campaigning is due to the authenticity of a political party’s brand values — creating a coherent brand story — if there is no distance between the brand values articulated by the political party and the values their community perceives then this creates an "authentic" brand. However, if there is a gap this paper illustrates how negative campaigning can be used to build a "doppelganger brand," which undermines the credibility of the authentic political brand. The paper argues that political parties need to understand how brand stories are developed but also how they can be used to protect against negative advertising. This has implications for political marketing strategists and political parties. This paper draws together branding theory and relationship marketing and incorporates them into a framework that makes a contribution to the political marketing literature

Ancient diversity and geographical sub-structuring in African buffalo Theileria parva populations revealed through metagenetic analysis of antigen-encoding loci

An infection and treatment protocol involving infection with a mixture of three parasite isolates and simultaneous treatment with oxytetracycline is currently used to vaccinate cattle against Theileria parva. While vaccination results in high levels of protection in some regions, little or no protection is observed in areas where animals are challenged predominantly by parasites of buffalo origin. A previous study involving sequencing of two antigen-encoding genes from a series of parasite isolates indicated that this is associated with greater antigenic diversity in buffalo-derived T. parva. The current study set out to extend these analyses by applying high-throughput sequencing to ex vivo samples from naturally infected buffalo to determine the extent of diversity in a set of antigen-encoding genes. Samples from two populations of buffalo, one in Kenya and the other in South Africa, were examined to investigate the effect of geographical distance on the nature of sequence diversity. The results revealed a number of significant findings. First, there was a variable degree of nucleotide sequence diversity in all gene segments examined, with the percentage of polymorphic nucleotides ranging from 10% to 69%. Second, large numbers of allelic variants of each gene were found in individual animals, indicating multiple infection events. Third, despite the observed diversity in nucleotide sequences, several of the gene products had highly conserved amino acid sequences, and thus represent potential candidates for vaccine development. Fourth, although compelling evidence for population differentiation between the Kenyan and South African T. parva parasites was identified, analysis of molecular variance for each gene revealed that the majority of the underlying nucleotide sequence polymorphism was common to both areas, indicating that much of this aspect of genetic variation in the parasite population arose prior to geographic separation

The influence of 'significant others' on persistent back pain and work participation: a qualitative exploration of illness perceptions

Background Individual illness perceptions have been highlighted as important influences on clinical outcomes for back pain. However, the illness perceptions of 'significant others' (spouse/partner/close family member) are rarely explored, particularly in relation to persistent back pain and work participation. The aim of this study was to initiate qualitative research in this area in order to further understand these wider influences on outcome. Methods Semi-structured interviews based on the chronic pain version of the Illness Perceptions Questionnaire-Revised were conducted with a convenience sample of UK disability benefit claimants, along with their significant others (n=5 dyads). Data were analysed using template analysis. Results Significant others shared, and perhaps further reinforced, claimants' unhelpful illness beliefs including fear of pain/re-injury associated with certain types of work and activity, and pessimism about the likelihood of return to work. In some cases, significant others appeared more resigned to the permanence and negative inevitable consequences of the claimant's back pain condition on work participation, and were more sceptical about the availability of suitable work and sympathy from employers. In their pursuit of authenticity, claimants were keen to stress their desire to work whilst emphasising how the severity and physical limitations of their condition prevented them from doing so. In this vein, and seemingly based on their perceptions of what makes a 'good' significant other, significant others acted as a 'witness to pain', supporting claimants' self-limiting behaviour and statements of incapacity, often responding with empathy and assistance. The beliefs and responses of significant others may also have been influenced by their own experience of chronic illness, thus participants lives were often intertwined and defined by illness. Conclusions The findings from this exploratory study reveal how others and wider social circumstances might contribute both to the propensity of persistent back pain and to its consequences. This is an area that has received little attention to date, and wider support of these findings may usefully inform the design of future intervention programmes aimed at restoring work participation

Does Stress Matter? Findings from a Self-Report Survey of Contract Cheating Behaviours of Canadian College Students

Presentation for the International Centre of Academic Integrity Annual Conference, March 2023.Othe

How Stressed are Students and What Can We Do About It? Findings from a Self-report Survey of Contract Cheating Behaviours and the Stressful Events College Students Experience

Empirical research on contract cheating in Canada has been limited (Eaton, 2022) and tends to focus on the university (Eaton, 2019; Stoesz & Los, 2019; Thacker, 2022) while there has been relatively little research on academic integrity and contract cheating in community colleges and other non-university higher education institutions (Bretag & Harper, 2020). To address this gap, in 2021, researchers collected data on student engagement in academic integrity violation behaviour and the stress they experienced as they were completing their programs at one Canadian community college. Using self-report survey methodology and utilizing students as partners in research, we found students engaged in a variety of contract cheating behaviours, and experienced a myriad of stressful events both in and outside the college context, including traumatic life events. In this presentation, we explore the link between stress and contract cheating behaviour and address how we can respond at all levels of our institutions to better support students and promote academic integrity.    &nbsp

Reframing centre-left neoliberalism: New Keynesian theory, Third Way ideology, and the construction of an elite consensus in the US, Britain, and Australia

This article aims to contribute to a growing literature on the role of social democratic and progressive parties in shaping neoliberalism. We argue that existing literature has not fully recognised the unique intellectual and ideological traditions of the Centre-Left as a distinctive wing of neoliberalism. Much of this confusion can be resolved by examining the unique ideological contributions of New Keynesian economics in the context of a Gramscian political analysis. Focusing on Centre-Left Anglo-American governments in the US, Britain, and Australia throughout the 1990s and 2000s, we demonstrate how New Keynesian theories provided the intellectual justification for the Third Way’s ideological project and model of state interventionism at the height of the neoliberal period. While Centre-Left political parties in these Anglo-American states have recently sought to re-invent themselves under a new interventionist economic paradigm, we conclude by showing how they have continued to reproduce orthodoxies associated with the New Keynesian consensus

Uncoupling protein-1 (UCP1) contributes to the basal proton conductance of brown adipose tissue mitochondria

Proton leak pathways uncouple substrate oxidation from ATP synthesis in mitochondria. These pathways are classified as basal (not regulated) or inducible (activated and inhibited). Previously it was found that over half of the basal proton conductance of muscle mitochondria was catalyzed by the adenine nucleotide translocase (ANT), an abundant mitochondrial anion carrier protein. To determine whether ANT is the unique protein catalyst, or one of many proteins that catalyze basal proton conductance, we measured proton leak kinetics in mitochondria isolated from brown adipose tissue (BAT). BAT can express another mitochondrial anion carrier, UCP1, at concentrations similar to ANT. Basal proton conductance was measured under conditions where UCP1 and ANT were catalytically inactive and was found to be lower in mitochondria from UCP1 knockout mice compared to wild-type. Ablation of another abundant inner membrane protein, nicotinamide nucleotide transhydrogenase, had no effect on proton leak kinetics in mitochondria from liver, kidney or muscle, showing that basal proton conductance is not catalyzed by all membrane proteins. We identify UCP1 as a second protein propagating basal proton leak, lending support to the hypothesis that basal leak pathways are perpetrated by members of the mitochondrial anion carrier family but not by other mitochondrial inner membrane proteins