596 research outputs found
Analyzing power for the proton elastic scattering from neutron-rich 6He nucleus
Vector analyzing power for the proton-6He elastic scattering at 71
MeV/nucleon has been measured for the first time, with a newly developed
polarized proton solid target working at low magnetic field of 0.09 T. The
results are found to be incompatible with a t-matrix folding model prediction.
Comparisons of the data with g-matrix folding analyses clearly show that the
vector analyzing power is sensitive to the nuclear structure model used in the
reaction analysis. The alpha-core distribution in 6He is suggested to be a
possible key to understand the nuclear structure sensitivity.Comment: 5 pages, 3 figures, accepted for publication as a Rapid Communication
in Physical Review
Retrograde semaphorin-plexin signalling drives homeostatic synaptic plasticity.
Homeostatic signalling systems ensure stable but flexible neural activity and animal behaviour. Presynaptic homeostatic plasticity is a conserved form of neuronal homeostatic signalling that is observed in organisms ranging from Drosophila to human. Defining the underlying molecular mechanisms of neuronal homeostatic signalling will be essential in order to establish clear connections to the causes and progression of neurological disease. During neural development, semaphorin-plexin signalling instructs axon guidance and neuronal morphogenesis. However, semaphorins and plexins are also expressed in the adult brain. Here we show that semaphorin 2b (Sema2b) is a target-derived signal that acts upon presynaptic plexin B (PlexB) receptors to mediate the retrograde, homeostatic control of presynaptic neurotransmitter release at the neuromuscular junction in Drosophila. Further, we show that Sema2b-PlexB signalling regulates presynaptic homeostatic plasticity through the cytoplasmic protein Mical and the oxoreductase-dependent control of presynaptic actin. We propose that semaphorin-plexin signalling is an essential platform for the stabilization of synaptic transmission throughout the developing and mature nervous system. These findings may be relevant to the aetiology and treatment of diverse neurological and psychiatric diseases that are characterized by altered or inappropriate neural function and behaviour
The cellular and synaptic architecture of the mechanosensory dorsal horn
The deep dorsal horn is a poorly characterized spinal cord region implicated in processing low-threshold mechanoreceptor (LTMR) information. We report an array of mouse genetic tools for defining neuronal components and functions of the dorsal horn LTMR-recipient zone (LTMR-RZ), a role for LTMR-RZ processing in tactile perception, and the basic logic of LTMR-RZ organization. We found an unexpectedly high degree of neuronal diversity in the LTMR-RZ: seven excitatory and four inhibitory subtypes of interneurons exhibiting unique morphological, physiological, and synaptic properties. Remarkably, LTMRs form synapses on between four and 11 LTMR-RZ interneuron subtypes, while each LTMR-RZ interneuron subtype samples inputs from at least one to three LTMR classes, as well as spinal cord interneurons and corticospinal neurons. Thus, the LTMR-RZ is a somatosensory processing region endowed with a neuronal complexity that rivals the retina and functions to pattern the activity of ascending touch pathways that underlie tactile perception
Nuclear Physics Experiments with Ion Storage Rings
In the last two decades a number of nuclear structure and astrophysics
experiments were performed at heavy-ion storage rings employing unique
experimental conditions offered by such machines. Furthermore, building on the
experience gained at the two facilities presently in operation, several new
storage ring projects were launched worldwide. This contribution is intended to
provide a brief review of the fast growing field of nuclear structure and
astrophysics research at storage rings.Comment: XVIth International Conference on Electro-Magnetic Isotope Separators
and Techniques Related to their Applications, December 2--7, 2012 at Matsue,
Japa
Reaction mechanism and characteristics of T_{20} in d + ^3He backward elastic scattering at intermediate energies
For backward elastic scattering of deuterons by ^3He, cross sections \sigma
and tensor analyzing power T_{20} are measured at E_d=140-270 MeV. The data are
analyzed by the PWIA and by the general formula which includes virtual
excitations of other channels, with the assumption of the proton transfer from
^3He to the deuteron. Using ^3He wave functions calculated by the Faddeev
equation, the PWIA describes global features of the experimental data, while
the virtual excitation effects are important for quantitative fits to the
T_{20} data. Theoretical predictions on T_{20}, K_y^y (polarization transfer
coefficient) and C_{yy} (spin correlation coefficient) are provided up to GeV
energies.Comment: REVTEX+epsfig, 17 pages including 6 eps figs, to be published in
Phys. Rev.
Ancient evolutionary origin of vertebrate enteric neurons from trunk-derived neural crest
The enteric nervous system of jawed vertebrates arises primarily from vagal neural crest cells that migrate to the foregut and subsequently colonize and innervate the entire gastrointestinal tract. Here we examine development of the enteric nervous system in the basal jawless vertebrate the sea lamprey (Petromyzon marinus) to gain insight into its evolutionary origin. Surprisingly, we find no evidence for the existence of a vagally derived enteric neural crest population in the lamprey. Rather, labelling with the lipophilic dye DiI shows that late-migrating cells, originating from the trunk neural tube and associated with nerve fibres, differentiate into neurons within the gut wall and typhlosole. We propose that these trunk-derived neural crest cells may be homologous to Schwann cell precursors, recently shown in mammalian embryos to populate post-embryonic parasympathetic ganglia, including enteric ganglia. Our results suggest that neural-crest-derived Schwann cell precursors made an important contribution to the ancient enteric nervous system of early jawless vertebrates, a role that was largely subsumed by vagal neural crest cells in early gnathostomes
Ignition conditions for inertial confinement fusion targets with a nuclear spin-polarized DT fuel
The nuclear fusion cross-section is modified when the spins of the interacting nuclei are polarized. In the case of deuterium?tritium it has been theoretically predicted that the nuclear fusion cross-section could be increased by a factor d = 1.5 if all the nuclei were polarized. In inertial confinement fusion this would result in a modification of the required ignition conditions. Using numerical simulations it is found that the required hot-spot temperature and areal density can both be reduced by about 15% for a fully polarized nuclear fuel. Moreover, numerical simulations of a directly driven capsule show that the required laser power and energy to achieve a high gain scale as d-0.6 and d-0.4 respectively, while the maximum achievable energy gain scales as d0.9
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