Capital Fixity and Mobility in Response to the 2008-09 Crisis: Variegated Neoliberalism in Mexico and Turkey

The article examines the 2008-9 crisis responses in Mexico and Turkey as examples of variegated neoliberalism. The simultaneous interests of corporations and banks relative to the national fixing of capital and their mobility in the form of global investment heavily influenced each state authority’s policy responses to the crisis at the expense of the interests of the poor, workers, and peasantry. Rather than pitching this as either evidence of persistent national differentiation or some Keynesian state resurgence, we argue from a historical materialist geographical framework that the responses of capital and state authorities in Mexico and Turkey actively constitute and reconstitute the global parameters of market regulatory design and neoliberal class rule through each state’s distinct domestic policy formation and crisis management processes. While differing in specific content the form of Mexico and Turkey’s state responses to the crisis ensured continuity in their foregoing neoliberal strategies of development and capital accumulation, most notably in the continued oppression of workers. That is, the prevailing strategy of accumulation continues to be variegated neoliberalism

A wideband linear tunable CDTA and its application in field programmable analogue array

This document is the Accepted Manuscript version of the following article: Hu, Z., Wang, C., Sun, J. et al. ‘A wideband linear tunable CDTA and its application in field programmable analogue array’, Analog Integrated Circuits and Signal Processing, Vol. 88 (3): 465-483, September 2016. Under embargo. Embargo end date: 6 June 2017. The final publication is available at Springer via https://link.springer.com/article/10.1007%2Fs10470-016-0772-7 © Springer Science+Business Media New York 2016In this paper, a NMOS-based wideband low power and linear tunable transconductance current differencing transconductance amplifier (CDTA) is presented. Based on the NMOS CDTA, a novel simple and easily reconfigurable configurable analogue block (CAB) is designed. Moreover, using the novel CAB, a simple and versatile butterfly-shaped FPAA structure is introduced. The FPAA consists of six identical CABs, and it could realize six order current-mode low pass filter, second order current-mode universal filter, current-mode quadrature oscillator, current-mode multi-phase oscillator and current-mode multiplier for analog signal processing. The Cadence IC Design Tools 5.1.41 post-layout simulation and measurement results are included to confirm the theory.Peer reviewedFinal Accepted Versio

Communication Research

Contains reports on seven research projects.Rockefeller FoundationCarnegie Foundatio

Communication Research

Contains reports on nine research projects.Bell Telephone Laboratories, Incorporate

Communication Research

Contains reports on five research projects.Rand Corporatio

Modeling for sustainable groundwater management: Interdependence and potential complementarity of process-based, data-driven and system dynamics approaches

Groundwater systems are vast natural water reservoirs used to support human water demands and ecosystem services. Various modeling approaches have been developed to help manage these complex highly-dynamic systems. This paper discusses the strengths and limitations of three modeling approaches, namely: process-based, data-driven and system dynamics modeling. For demonstration purposes, the three modeling approaches are applied to the Konya Closed Basin, a large agricultural region with semi-dry climate located in central Turkey. Process-based modeling is grounded in the theory-based representation of the governing processes but is somewhat limited by the computational effort and the difficulty of defining the required input parameters that characterize the heterogeneous aquifer system. Process-based models are shown to be powerful tools for resource management purposes provided climatic and water demand scenarios are accurately defined. Data-driven models are efficient tools for the management of groundwater resources but are highly dependent on the availability of large training data sets encompassing the spectrum of possible system responses. The high efficiency of surrogate modeling approaches makes them ideal tools for incorporation into applications such as real-time decision support systems and digital twin platforms. System dynamics modeling examines the groundwater exploitation problem within a socio-economic context that involves multiple stakeholders and their decision making. It combines groundwater flow models with socio-economics and endogenous decision rules to conduct scenario analysis and support policy development. The analyses and model demonstrations presented in this paper underscore the interconnectedness and complementarity of these three modeling approaches and the need for more integrated use of these modeling approaches for enhanced multi-sectoral management of groundwater systems

Recommendations for the diagnosis of pediatric tuberculosis

Tuberculosis (TB) is still the world's second most frequent cause of death due to infectious diseases after HIV infection, and this has aroused greater interest in identifying and managing exposed subjects, whether they are simply infected or have developed one of the clinical variants of the disease. Unfortunately, not even the latest laboratory techniques are always successful in identifying affected children because they are more likely to have negative cultures and tuberculin skin test results, equivocal chest X-ray findings, and atypical clinical manifestations than adults. Furthermore, they are at greater risk of progressing from infection to active disease, particularly if they are very young. Consequently, pediatricians have to use different diagnostic strategies that specifically address the needs of children. This document describes the recommendations of a group of scientific societies concerning the signs and symptoms suggesting pediatric TB, and the diagnostic approach towards children with suspected disease

Novel roles for class II Phosphoinositide 3-Kinase C2 beta in signalling pathways involved in prostate cancer cell invasion

Phosphoinositide 3-kinases (PI3Ks) regulate several cellular functions such as proliferation, growth, survival and migration. The eight PI3K isoforms are grouped into three classes and the three enzymes belonging to the class II subfamily (PI3K-C2a, ß and ?) are the least investigated amongst all PI3Ks. Interest on these isoforms has been recently fuelled by the identification of specific physiological roles for class II PI3Ks and by accumulating evidence indicating their involvement in human diseases. While it is now established that these isoforms can regulate distinct cellular functions compared to other PI3Ks, there is still a limited understanding of the signalling pathways that can be specifically regulated by class II PI3Ks. Here we show that PI3K-C2ß regulates mitogen-activated protein kinase kinase (MEK1/2) and extracellular signal-regulated kinase (ERK1/2) activation in prostate cancer (PCa) cells. We further demonstrate that MEK/ERK and PI3K-C2ß are required for PCa cell invasion but not proliferation. In addition we show that PI3K-C2ß but not MEK/ERK regulates PCa cell migration as well as expression of the transcription factor Slug. These data identify novel signalling pathways specifically regulated by PI3K-C2ß and they further identify this enzyme as a key regulator of PCa cell migration and invasion

Wellbeing in the wild: co-creating context-sensitive wellbeing dimensions with a community of young artists

Background: This study addresses the challenge of developing context-sensitive measures of wellbeing for young people. In collaboration with a youth-led musical enterprise, researchers worked with 18 young artists (aged 14–25) engaged in an urban community arts programme to co-produce wellbeing dimensions reflective of their lived experiences. Methods: An adapted Nominal Group Technique was used alongside iterative inductive thematic analysis to identify and prioritise key wellbeing dimensions. Results: The study revealed ten discrete dimensions of wellbeing that reflect the experiences of young people engaged in community arts. These dimensions highlight the significance of creative expression, cultural appreciation, community experiences, and social responsibility, elements aligned with wellbeing but rarely considered in standardised wellbeing frameworks. Conclusion: The study highlights the value of youth-led, situated approaches to defining dimensions of wellbeing, offering a framework that captures the creative and social dimensions in community arts contexts.The project was funded by an accelerated knowledge transfer partnership fund provided by [UKRI, Ref:1629-AKT] Innovate UK