Is Development Assistance Getting Better Due to the Widening Role of Emerging Economies?

There is a seismic shift emerging in the way that the international development assistance regime is conceived, managed and run. It has two primary causes: Firstly, the weaknesses and limitations of the existing system, as grounded in the hegemonic and exclusionary power and influence of the West. Secondly, the arrival of the “emerging economies” with globalization, which are challenging the structural institutional architecture, central principles and underlying values of the old system, along with its managerial system and effectiveness of delivery. A central and critical aim of these emerging states is the fundamental and irreversible reform of the existing system and, even more radical, a fundamental change in the way international development assistance is understood. The New Development Assistance (NDA) practiced by these states reflects many influences, the most important of which are their historical experiences as colonies or semi-colonized countries and their long, often bitter paths to independence, reform and renaissance, and their experiences as recipients of international development assistance. Within this shared generic experience, each brings their own distinctive history, understanding and practices of development to NDA. At the center of NDA is the complex relationship between the traditional system and its counter-point, an intricate diachronic process. In this process, the agencies of NDA engage with the principles, structures, processes and practices of the OECD DAC system. In this respect, NDA is selectively learning from the “traditional” system whilst simultaneously stepping away from it to establish a “new” institutional architecture predicated on distinct principles and practices that deviate from that system.<br/

Smart cities in a smart world

Very often the concept of smart city is strongly related to the flourishing of mobile applications, stressing the technological aspects and a top-down approach of high-tech centralized control systems capable of resolving all the urban issues, completely forgetting the essence of a city with its connected problems. The real challenge in future years will be a huge increase in the urban population and the changes this will produce in energy and resource consumption. It is fundamental to manage this phenomenon with clever approaches in order to guarantee a better management of resources and their sustainable access to present and future generations. This chapter develops some considerations on these aspects, trying to insert the technological issues within a framework closer to planning and with attention to the social impact

Solvent accessible surface area approximations for rapid and accurate protein structure prediction

The burial of hydrophobic amino acids in the protein core is a driving force in protein folding. The extent to which an amino acid interacts with the solvent and the protein core is naturally proportional to the surface area exposed to these environments. However, an accurate calculation of the solvent-accessible surface area (SASA), a geometric measure of this exposure, is numerically demanding as it is not pair-wise decomposable. Furthermore, it depends on a full-atom representation of the molecule. This manuscript introduces a series of four SASA approximations of increasing computational complexity and accuracy as well as knowledge-based environment free energy potentials based on these SASA approximations. Their ability to distinguish correctly from incorrectly folded protein models is assessed to balance speed and accuracy for protein structure prediction. We find the newly developed “Neighbor Vector” algorithm provides the most optimal balance of accurate yet rapid exposure measures

Grist to the Mill of Anti-evolutionism: The Failed Strategy of Ruling the Supernatural Out of Science by Philosophical Fiat

According to a widespread philosophical opinion, science is strictly limited to investigating natural causes and putting forth natural explanations. Lacking the tools to evaluate supernatural claims, science must remain studiously neutral on questions of metaphysics. This (self-imposed) stricture, which goes under the name of ‘methodological naturalism’, allows science to be divorced from metaphysical naturalism or atheism, which many people tend to associate with it. However, ruling the supernatural out of science by fiat is not only philosophically untenable, it actually provides grist to the mill of anti-evolutionism. The philosophical flaws in this conception of methodological naturalism have been gratefully exploited by advocates of Intelligent Design Creationism to bolster their false accusations of naturalistic bias and dogmatism on the part of modern science. We argue that it promotes a misleading view of the scientific endeavor and is at odds with the foremost arguments for evolution by natural selection. Reconciling science and religion on the basis of such methodological strictures is therefore misguided

Elinsiirron saaneen nuoren siirtyminen lasten ja nuorten hoitotyöstä aikuisten terveyspalveluiden käyttäjäksi

Opinnäytetyömme tarkoituksena on kuvata saumaton, hoitoon sitoutumista tukeva hoitopolku nuoren elinsiirtopotilaan siirtyessä lasten ja nuorten hoitotyöstä aikuisten terveyspalvelujen käyttäjäksi. Työmme on osa lasten ja nuorten hoitotyön osaamisen tulevaisuuden hanketta. Hankkeen tarkoituksena on uusien toimintakäytäntöjen luominen, verkostomaisen työskentelyn vahvistaminen, sekä saumattomien hoitopolkujen kehittäminen. Hankkeessa yhteistyökumppaneina ovat HYKS Naisten- ja lastentautien tulosyksikkö, Metropolia ammattikorkeakoulun Hoitotyön koulutusohjelma ja Tampereen yliopiston Hoitotieteen laitos. Työssämme keskitymme potilaan siirtymävaiheen solmukohtiin, kuvaamme nykyisen hoitopolun ja pyrimme löytämään näkökulmia sekä toimintamalleja, jotka antaisivat nuorelle, hänen perheelleen sekä hoitoyksikölle valmiuksia siirtymisprosessin vaiheisiin. Työssämme keskitymme nuorten kehittymishaasteisiin ja pyrimme kartoittamaan nuorten hoitomyönteisyyttä ja vastaanottavaisuutta edistäviä keinoja ja välineitä. Opinnäytetyömme aihe on uusi hoitotieteellisen tutkimuksen kohde ja löytämämme materiaali on luonteeltaan täsmällistä, tuoretta ja vastaa hyvin työmme edistymisen vaateisiin. Käytimme työssämme kvantitatiivista tutkimusmenetelmää. Tutkimustyön tarve sekä prosessin kehittäminen potilaan tarpeita vastaavaksi tällä hoitotyön saralla on erittäin tärkeää. Kansainvälisesti siirtymisessä koetaan haastavimmaksi prosessin alkamisen äkillisyys, riittämätön tiedonkulku lasten ja aikuisten puolen välillä ja tätä kautta hoidon jatkuvuuden kankeus. Toisin sanoen siirtymiseen valmistavien toimintojen aikaistaminen, kirjallinen informaatio ja sujuvampi yhteistyö palveluiden tarjoajien välillä, ovat suurimmat kehittymishaasteet

Prediction of Cardiovascular Risk in Hemodialysis Patients by Data Mining

Summary Objectives: The objective of this work was to contribute to the development, validation and application of data mining methods for prediction in decision support systems in medicine. The particular focus was on the prediction of cardiovascular risk factors in hemodialysis patients, specifically the interventricular septum (IVS) thickness of the heart of individual patients as an important quantitative indicator to diagnose left ventricular hypertrophy. The work was based on data from 63 long-term hemodialysis patients of the KfH Dialysis Centre in Jena, Germany. Methods: The approach applied is based on data mining methods and involves four major steps: data based clustering, cluster based rule extraction, rulebase construction and cluster and rule based prediction. The methods employed include crisp and fuzzy algorithms. At each step, logical and medical validation of results was carried out. Different sets of randomly selected patient data were used to train, test and optimize the clusterbases and rulebases for prediction. Results: Using the best clusterbase/rulebase combination designed, the IVS thickness cluster (‘small’ or ‘large’) was predicted correctly for 30 of the 35 patients with known IVS values in the training data set; no patient was predicted incorrectly and 5 were parity predicted. For the test data set, 4 of the 6 patients with known IVS values were predicted correctly, no patient incorrectly and 2 parity. These results did not substantially differ from those obtained using the second best clusterbase/rulebase combination which was finally recommended for use based on further performance criteria. The prediction of the IVS thickness clusters of the 22 patients with unknown IVS values also yielded good results that were (and could only be) validated by a medical individual risk assessment of these patients. Conclusions: The approach applied proved successful for the cluster and rule based prediction of a quantitative variable, such as IVS thickness, for individual patients from other variables relevant to the problem. The results obtained demonstrate the high potential of the approach and the methods developed and validated to support decision-making in hemodialysis and other fields of medicine by individual risk prediction.</jats:p

Basic support for cooperative work on the World Wide Web

The emergence and widespread adoption of the World Wide Web offers a great deal of potential in supporting cross-platform cooperative work within widely dispersed working groups. The Basic Support for Cooperative Work (BSCW) project at GMD is attempting to realize this potential through development of web-based tools which provide cross-platform collaboration services to groups using existing web technologies. This paper describes one of these tools, theBSCW Shared Workspace system—a centralized cooperative application integrated with an unmodified web server and accessible from standard web browsers. The BSCW system supports cooperation through “shared workspaces”; small repositories in which users can upload documents, hold threaded discussions and obtain information on the previous activities of other users to coordinate their own work. The current version of the system is described in detail, including design choices resulting from use of the web as a cooperation platform and feedback from users following the release of a previous version of BSCW to the public domain

World Wide Web

The emergence and widespread adoption of the World Wide Web offers a great deal of potential in supporting cross-platform cooperative work within widely-dispersed working groups. The Basic Support for Cooperative Work (BSCW) project at GMD is attempting to realise this potential through development of Web-based tools which provide cross-platform collaboration services to groups using existing Web technologies. This paper describes one of these tools, the BSCW Shared Workspace system—a centralised cooperative application integrated with an unmodified Web server and accessible from standard Web browsers. The BSCW system supports cooperation through ‘shared workspaces’; small repositories in which users can upload documents, hold threaded discussions, and obtain information on the previous activities of other users to coordinate their own work. The current version of the system is described in detail, including design choices resulting from use of the Web as a cooperation platform and feedback from users following the release of a previous version of BSCW to the public domain