Experimental Setup for Splash Erosion Monitoring—Study of Silty Loam Splash Characteristics

An experimental laboratory setup was developed and evaluated in order to investigate detachment of soil particles by raindrop splash impact. The soil under investigation was a silty loam Cambisol, which is typical for agricultural fields in Central Europe. The setup consisted of a rainfall simulator and soil samples packed into splash cups (a plastic cylinder with a surface area of 78.5 cm2) positioned in the center of sediment collectors with an outer diameter of 45 cm. A laboratory rainfall simulator was used to simulate rainfall with a prescribed intensity and kinetic energy. Photographs of the soil’s surface before and after the experiments were taken to create digital models of relief and to calculate changes in surface roughness and the rate of soil compaction. The corresponding amount of splashed soil ranged between 10 and 1500 g m−2 h−1. We observed a linear relationship between the rainfall kinetic energy and the amount of the detached soil particles. The threshold kinetic energy necessary to initiate the detachment process was 354 J m−2 h−1. No significant relationship between rainfall kinetic energy and splashed sediment particle-size distribution was observed. The splash erosion process exhibited high variability within each repetition, suggesting a sensitivity of the process to the actual soil surface microtopography

Pancreatic cancer-associated diabetes mellitus: an open field for proteomic applications.

Background: Diabetes mellitus is associated with pancreatic cancer in more than 80% of the cases. Clinical, epidemiological, and experimental data indicate that pancreatic cancer causes diabetes mellitus by releasing soluble mediators which interfere with both beta-cell function and liver and muscle glucose metabolism. Methods: We analysed, by matrix-assisted laser desorption ionization time of flight (MALDI-TOF), a series of pancreatic cancer cell lines conditioned media, pancreatic cancer patients' peripheral and portal sera, comparing them with controls and chronic pancreatitis patients' sera. Results: MALDI-TOF analysis of pancreatic cancer cells conditioned media and patients' sera indicated a low molecular weight peptide to be the putative pancreatic cancer-associated diabetogenic factor. The sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) analysis of tumor samples from diabetic and non-diabetic patients revealed the presence of a 1500 Da peptide only in diabetic patients. The amino acid sequence of this peptide corresponded to the N-terminal of an S-100 calcium binding protein, which was therefore suggested to be the pancreatic cancer-associated diabetogenic factor. Conclusions: We identified a tumor-derived peptide of 14 amino acids sharing a 100% homology with an S-100 calcium binding protein, which is probably the pancreatic cancer-associated diabetogenic facto

Pancreatic cancer-derived S-100A8 N-terminal peptide: a diabetes cause?

BACKGROUND: Our aim was to identify the pancreatic cancer diabetogenic peptide. METHODS: Pancreatic tumor samples from patients with (n=15) or without (n=7) diabetes were compared with 6 non-neoplastic pancreas samples using SDS-PAGE. RESULTS: A band measuring approximately 1500 Da was detected in tumors from diabetics, but not in neoplastic samples from non-diabetics or samples from non-neoplastic subjects. Sequence analysis revealed a 14 amino acid peptide (1589.88 Da), corresponding to the N-terminal of the S100A8. At 50 nmol/L and 2 mmol/L, this peptide significantly reduced glucose consumption and lactate production by cultured C(2)C(12) myoblasts. The 14 amino acid peptide caused a lack of myotubular differentiation, the presence of polynucleated cells and caspase-3 activation. CONCLUSIONS: The 14 amino acid peptide from S100A8 impairs the catabolism of glucose by myoblasts in vitro and may cause hyperglycemia in vivo. Its identification in biological fluids might be helpful in diagnosing pancreatic cancer in patients with recent onset diabetes mellitus

The valuation of European financial firms

We extend the recent literature concerning accounting based valuation models to investigate financial firms from six European countries with substantial financial sectors: France, Germany, Italy, Netherlands, Switzerland and the UK. Not only are these crucial industries worthy of study in their own right, but unusual accounting practices, and inter-country differences in those accounting practices, provide valuable insights into the accounting-value relationship. Our sample consists of 7,714 financial firm/years observations from 1,140 companies drawn from 1989-2000. Sub-samples include 1,309 firm/years for banks, 650 for insurance companies, 1,705 for real estate firms, and 3,239 for investment companies. In most countries we find that the valuation models work as well or better in explaining cross-sectional variations in the market-to-book ratio for financial firms as they do for industrial and commercial firms in the same countries, although Switzerland is an exception to this generalization. As expected, the results are sensitive to industrial differences, accounting regulation and accounting practices. In particular, marking assets to market value reduces the relevance of earnings figures and increases that of equity

Integration of Dirac-Jacobi structures

We study precontact groupoids whose infinitesimal counterparts are Dirac-Jacobi structures. These geometric objects generalize contact groupoids. We also explain the relationship between precontact groupoids and homogeneous presymplectic groupoids. Finally, we present some examples of precontact groupoids.Comment: 10 pages. Brief changes in the introduction. References update

Efficient Passive ICS Device Discovery and Identification by MAC Address Correlation

Owing to a growing number of attacks, the assessment of Industrial Control Systems (ICSs) has gained in importance. An integral part of an assessment is the creation of a detailed inventory of all connected devices, enabling vulnerability evaluations. For this purpose, scans of networks are crucial. Active scanning, which generates irregular traffic, is a method to get an overview of connected and active devices. Since such additional traffic may lead to an unexpected behavior of devices, active scanning methods should be avoided in critical infrastructure networks. In such cases, passive network monitoring offers an alternative, which is often used in conjunction with complex deep-packet inspection techniques. There are very few publications on lightweight passive scanning methodologies for industrial networks. In this paper, we propose a lightweight passive network monitoring technique using an efficient Media Access Control (MAC) address-based identification of industrial devices. Based on an incomplete set of known MAC address to device associations, the presented method can guess correct device and vendor information. Proving the feasibility of the method, an implementation is also introduced and evaluated regarding its efficiency. The feasibility of predicting a specific device/vendor combination is demonstrated by having similar devices in the database. In our ICS testbed, we reached a host discovery rate of 100% at an identification rate of more than 66%, outperforming the results of existing tools.Comment: http://dx.doi.org/10.14236/ewic/ICS2018.

Age-specific vaccine effectiveness of seasonal 2010/2011 and pandemic influenza A(H1N1) 2009 vaccines in preventing influenza in the United Kingdom

An analysis was undertaken to measure age-specific vaccine effectiveness (VE) of 2010/11 trivalent seasonal influenza vaccine (TIV) and monovalent 2009 pandemic influenza vaccine (PIV) administered in 2009/2010. The test-negative case-control study design was employed based on patients consulting primary care. Overall TIV effectiveness, adjusted for age and month, against confirmed influenza A(H1N1)pdm 2009 infection was 56% (95% CI 42–66); age-specific adjusted VE was 87% (95% CI 45–97) in <5-year-olds and 84% (95% CI 27–97) in 5- to 14-year-olds. Adjusted VE for PIV was only 28% (95% CI x6 to 51) overall and 72% (95% CI 15–91) in <5-year-olds. For confirmed influenza B infection, TIV effectiveness was 57% (95% CI 42–68) and in 5- to 14-year-olds 75% (95% CI 32–91). TIV provided moderate protection against the main circulating strains in 2010/2011, with higher protection in children. PIV administered during the previous season provided residual protection after 1 year, particularly in the <5 years age group

Pengaruh Fraksi Penipisan (P) Air Tanah Tersedia Pada Berbagai Fase Tumbuh Terhadap Pertumbuhan, Hasil Dan Efisiensi Penggunaan Air Tanaman Kedelai (Glycine Max [L] Merr.)

Penelitian bertujuan untuk mengetahui pengaruh fraksi penipisan (p) air tanah tersedia pada berbagai fase tumbuh terhadap pertumbuhan dan efisiensi penggunaan air tanaman kedelai. Penelitian ini dilaksanakan di dalam rumah plastik, laboratorium lapang terpadu, Universitas Lampung pada bulan Oktober 2015 sampai dengan Januari 2016. Penelitian ini menggunakan rancangan Faktorial dalam Acak Lengkap (RAL) dengan 2 faktor perlakuan, yaitu faktor I (Fraksi penipisan air tanah tersedia, p) dan faktor II (fase tumbuh, F). Masing-masing perlakuan terdiri dari 3 taraf, yaitu faktor I terdiri dari P1(0,2), P2(0,4) dan P3(0,6) dari penipisan air tanah tersedia, dan faktor II terdiri dari fase vegetatif aktif (F1), fase pembungaan (F2), dan fase pembentukan polong (F3), dengan ulangan sebanyak 3 kali. Pengukuran evapotranspirasi tanaman acuan dilakukan pada fraksi penipisan 0,2 dari air tanah tersedia dengan menggunakan tanaman rumput. Hasil penelitian menunjukkan bahwa, perlakuan fraksi penipisan (p) air tanah tersedia pada berbagai fase tumbuhtidak berpengaruh terhadap pertumbuhan dan efisiensi penggunaan air tanaman kedelai.Tanaman kedelai pada perlakuan fraksi penipisan (p) air tanah tersedia tidak mengalami cekaman air pada semua perlakuan, karena tanaman sebelum mendekati batas bawah perlakuan segera diberi irigasi dan dikembalikan ke kondisi kapasitas lapang. Produksi tertinggi dengan nilai efisiensi penggunaan air tertinggi dicapai oleh perlakuan fraksi penipisan (0-0,2) air tanah tersedia pada perlakuan fase pembungaan (F2). Tanaman kedelai menghasilkan produksi yang tinggi pada fraksi penipisan 0,4 untuk perlakuan fase pertumbuhan aktif dan fraksi penipisan 0,2 untuk perlakuan fase pembungaan dan fase pengisian polong