Time delays in quasi-periodic pulsations observed during the X2.2 solar flare on 2011 February 15

We report observations of quasi-periodic pulsations (QPPs) during the X2.2 flare of 2011 February 15, observed simultaneously in several wavebands. We focus on fluctuations on time scale 1-30 s and find different time lags between different wavebands. During the impulsive phase, the Reuven Ramaty High Energy Solar Spectroscopic Imager (RHESSI) channels in the range 25-100 keV lead all the other channels. They are followed by the Nobeyama RadioPolarimeters at 9 and 17 GHz and the Extreme Ultra-Violet (EUV) channels of the Euv SpectroPhotometer (ESP) onboard the Solar Dynamic Observatory (SDO). The Zirconium and Aluminum filter channels of the Large Yield Radiometer (LYRA) onboard the Project for On-Board Autonomy (PROBA2) satellite and the SXR channel of ESP follow. The largest lags occur in observations from the Geostationary Operational Environmental Satellite (GOES), where the channel at 1-8 {\AA} leads the 0.5-4 {\AA} channel by several seconds. The time lags between the first and last channels is up to 9 s. We identified at least two distinct time intervals during the flare impulsive phase, during which the QPPs were associated with two different sources in the Nobeyama RadioHeliograph at 17 GHz. The radio as well as the hard X-ray channels showed different lags during these two intervals. To our knowledge, this is the first time that time lags are reported between EUV and SXR fluctuations on these time scales. We discuss possible emission mechanisms and interpretations, including flare electron trapping

Quantum Computing with Continuous-Variable Clusters

Continuous-variable cluster states offer a potentially promising method of implementing a quantum computer. This paper extends and further refines theoretical foundations and protocols for experimental implementation. We give a cluster-state implementation of the cubic phase gate through photon detection, which, together with homodyne detection, facilitates universal quantum computation. In addition, we characterize the offline squeezed resources required to generate an arbitrary graph state through passive linear optics. Most significantly, we prove that there are universal states for which the offline squeezing per mode does not increase with the size of the cluster. Simple representations of continuous-variable graph states are introduced to analyze graph state transformations under measurement and the existence of universal continuous-variable resource states.Comment: 17 pages, 5 figure

Characterising smoking cessation smartphone applications in terms of behaviour change techniques, engagement and ease-of-use features

The aim of this study was to assess whether or not behaviour change techniques (BCTs) as well as engagement and ease-of-use features used in smartphone applications (apps) to aid smoking cessation can be identified reliably. Apps were coded for presence of potentially effective BCTs, and engagement and ease-of-use features. Inter-rater reliability for this coding was assessed. Inter-rater agreement for identifying presence of potentially effective BCTs ranged from 66.8 to 95.1 % with ‘prevalence and bias adjusted kappas’ (PABAK) ranging from 0.35 to 0.90 (p 50 % for rewarding abstinence. The average proportions of specified engagement and ease-of-use features included in the apps were 69 and 83 %, respectively. The study found that it is possible to identify potentially effective BCTs, and engagement and ease-of-use features in smoking cessation apps with fair to high inter-rater reliability

Dynamics of (SUSY) AdS Space Isometry Breaking

Actions governing the dynamics of the Nambu-Goldstone modes resulting from the spontaneous breaking of the SO(4,2) and $SU(2,2|1)$ isometries of five dimensional anti-de Sitter space ($AdS_{5}$) and SUSY $AdS_{5}\times S_1$ spaces respectively due to a restriction of the motion to embedded four dimensional $AdS_{4}$ space and four dimensional Minkowski space ($M_4$) probe branes are presented. The dilatonic Nambu-Goldstone mode governing the motion of the $M_4$ space probe brane into the covolume of the SUSY $AdS_5\times S_1$ space is found to be unstable. No such instablility appears in the other cases. Gauging these symmetries leads to an Einstein-Hilbert action containing, in addition to the gravitational vierbein, a massive Abelian vector field coupled to gravity.Comment: 6 pages, 0 figures, to appear in Proceedings of IRGAC 2006: 2nd International Conference on Quantum Theories and Renormalization Group in Gravity and Cosmology, Barcelon

Absolute photoionization cross section measurements of the Kr I-isoelectronic sequence

Photoionization spectra have been recorded in the 4s, 4p and 3d resonance regions for the Kr Iisoelectronic sequence using both the dual laser produced plasma technique (at DCU) to produce photoabsorption spectra, and the merged ion beam and synchrotron radiation technique (at ASTRID) to measure absolute photoionization cross sections. Profile parameters are compared for the 4s − np resonances of Rb+ and Sr2+. Many new 4p " ns, md transitions are identified with the aid of Hartree-Fock calculations, and consistent quantum defects are observed for the various ns and md Rydberg series. Absolute single and double photoionization cross sections recorded in the 3d region for Rb+ and Sr2+ ions show preferential decay via double photoionization. This is only the second report where both the DLP technique and the merged beam technique have been used simultaneously to record photoionization spectra, and the advantages of both techniques (i.e. better resolution in the case of DLP and values for absolute photoionization cross sections in the case of the merged beam technique) are highlighted

The Environments of Supernovae in Post-Refurbishment Hubble Space Telescope Images

The locations of supernovae in the local stellar and gaseous environment in galaxies contain important clues to their progenitor stars. Access to this information, however, has been hampered by the limited resolution achieved by ground-based observations. High spatial resolution Hubble Space Telescope (HST) images of galaxy fields in which supernovae had been observed can improve the situation considerably. We have examined the immediate environments of a few dozen supernovae using archival post-refurbishment HST images. Although our analysis is limited due to signal-to-noise ratio and filter bandpass considerations, the images allow us for the first time to resolve individual stars in, and to derive detailed color-magnitude diagrams for, several environments. We are able to place more rigorous constraints on the masses of these supernovae. A search was made for late-time emission from supernovae in the archival images, and for the progenitor stars in presupernova images of the host galaxies. We have detected SN 1986J in NGC 891 and, possibly, SN 1981K in NGC 4258. We have also identified the progenitor of the Type IIn SN 1997bs in NGC 3627. By removing younger resolved stars in the environments of SNe Ia, we can measure the colors of the unresolved stellar background and attribute these colors generally to an older, redder population. HST images ``accidentally'' caught the Type Ia SN 1994D in NGC 4526 shortly after its outburst; we measure its brightness. Finally, we add to the statistical inferences that can be made from studying the association of SNe with recent star-forming regions.Comment: 20 pages, 29 figures, to appear in A

The XIIIth Banff Conference on Allograft Pathology: The Banff 2015 Heart Meeting Report: Improving Antibody-Mediated Rejection Diagnostics: Strengths, Unmet Needs, and Future Directions.

The 13th Banff Conference on Allograft Pathology was held in Vancouver, British Columbia, Canada from October 5 to 10, 2015. The cardiac session was devoted to current diagnostic issues in heart transplantation with a focus on antibody-mediated rejection (AMR) and small vessel arteriopathy. Specific topics included the strengths and limitations of the current rejection grading system, the central role of microvascular injury in AMR and approaches to semiquantitative assessment of histopathologic and immunophenotypic indicators, the role of AMR in the development of cardiac allograft vasculopathy, the important role of serologic antibody detection in the management of transplant recipients, and the potential application of new molecular approaches to the elucidation of the pathophysiology of AMR and potential for improving the current diagnostic system. Herein we summarize the key points from the presentations, the comprehensive, open and wide-ranging multidisciplinary discussion that was generated, and considerations for future endeavors

A molecular insight into algal-oomycete warfare : cDNA analysis of Ectocarpus siliculosus infected with the basal oomycete Eurychasma dicksonii

Peer reviewedPublisher PD

Counting Complex Disordered States by Efficient Pattern Matching: Chromatic Polynomials and Potts Partition Functions

Counting problems, determining the number of possible states of a large system under certain constraints, play an important role in many areas of science. They naturally arise for complex disordered systems in physics and chemistry, in mathematical graph theory, and in computer science. Counting problems, however, are among the hardest problems to access computationally. Here, we suggest a novel method to access a benchmark counting problem, finding chromatic polynomials of graphs. We develop a vertex-oriented symbolic pattern matching algorithm that exploits the equivalence between the chromatic polynomial and the zero-temperature partition function of the Potts antiferromagnet on the same graph. Implementing this bottom-up algorithm using appropriate computer algebra, the new method outperforms standard top-down methods by several orders of magnitude, already for moderately sized graphs. As a first application, we compute chromatic polynomials of samples of the simple cubic lattice, for the first time computationally accessing three-dimensional lattices of physical relevance. The method offers straightforward generalizations to several other counting problems.Comment: 7 pages, 4 figure

Discovery of molecular subtypes in leiomyosarcoma through integrative molecular profiling.

Leiomyosarcoma (LMS) is a soft tissue tumor with a significant degree of morphologic and molecular heterogeneity. We used integrative molecular profiling to discover and characterize molecular subtypes of LMS. Gene expression profiling was performed on 51 LMS samples. Unsupervised clustering showed three reproducible LMS clusters. Array comparative genomic hybridization (aCGH) was performed on 20 LMS samples and showed that the molecular subtypes defined by gene expression showed distinct genomic changes. Tumors from the muscle-enriched cluster showed significantly increased copy number changes (P=0.04). A majority of the muscle-enriched cases showed loss at 16q24, which contains Fanconi anemia, complementation group A, known to have an important role in DNA repair, and loss at 1p36, which contains PRDM16, of which loss promotes muscle differentiation. Immunohistochemistry (IHC) was performed on LMS tissue microarrays (n=377) for five markers with high levels of messenger RNA in the muscle-enriched cluster (ACTG2, CASQ2, SLMAP, CFL2 and MYLK) and showed significantly correlated expression of the five proteins (all pairwise P<0.005). Expression of the five markers was associated with improved disease-specific survival in a multivariate Cox regression analysis (P<0.04). In this analysis that combined gene expression profiling, aCGH and IHC, we characterized distinct molecular LMS subtypes, provided insight into their pathogenesis, and identified prognostic biomarkers