A Review on Risk Management of Coronavirus Disease 19 (COVID-19) Infection in Dental Practice: Focus on Prosthodontics and All-Ceramic Materials

background: a novel β-coronavirus infection (COVID-19) was first detected in wuhan city, spreading rapidly to other countries and leading to a pandemic. dental professionals and patients are exposed to a high risk of COVID-19 infection, particularly in the prosthodontic practice, because of the bio-aerosol produced during teeth preparation with dental handpieces and the strict contact with oral fluids during impression making. this paper aimed to provide an overview to limit the risk of transmission of COVID-19 infections during prosthetic procedures in dental offices. methmds: an electronic search was conducted on the electronic databases of pubmed/medline, google scholar, embase, scopus, dynamed, and open grey with the following queries: (COVID-19) AND/OR (SARS-CoV-2) AND/OR (coronavirus) AND/OR (contaminated surface) AND/OR (cross-infection) AND/OR (Prosthodontics) AND/OR (dental ceramic) AND/OR (glass-ceramic). a manual search was performed as well. results: from the 1023 collected records, 32 papers were included. conclusions: dental offices are at high risk of spreading SARS-CoV-2 infection due to the close contact with patients and continuous exposure to saliva during dental procedures. therefore, pre-check triages via telephone, decontamination, the disinfection of impressions, the sterilization of scanner tips, and the use of specific personal protective equipment, dental high-speed handpieces with dedicated anti-retraction valves, and effective mouthwashes are strongly recommended

Evaluation by environmental monitoring of pesticide absorption in farm workers of 18 Italian tomato cultivations

Tornato cultivation farms of Soutbern Italy were investigated in order to evaluate tbe generai working conditions and tbe levels of exposure of farm workers to pesticides, during tbe mixinglloading and tbe application of pesticides on fields. Information on working modalities, personal protective equipment, etc. was collected using a questionnaire. Inbaling and cutaneous exposure levels were measured, and tbe estimated pesticide total absorbed dose was compared witb Admissible Daily Intakes (ADIs). Field treatments were mainly carried out by using sprayers witb open cab tractors, and, in 57 ~9% of cases, tbe pesticide mixture was manually prepared by mixing pesticides in a paU, often witbout using gloves (59.5%). Tbe estimated pesticides absorbed doses varied in tbe range 0.56-2630.31 mg (mean value, 46.9 mg), and 20% of tbe measured absorbed doses exceeded ADIs. Tbe findings obtained in tbe 18 examined farms sbow a worrying situation, suggesting tbe investigation of many more farms, so tbat a statistically significant picture of tornato cultivations in Soutbern Italy could be formed. Besides, tbe planning of training courses aimed to increase workers consciousness about bealtb risks and bow tbey can be prevented is advisable

The Utility of Capsicum annuum L. in Internal Medicine and In Dentistry: A Comprehensive Review

Capsaicin is a chili peppers extract, genus Capsicum, commonly used as a food spice. Since ancient times, Capsaicin has been used as a "homeopathic remedy" for treating a wild range of pathological conditions but without any scientific knowledge about its action. Several studies have demonstrated its potentiality in cardiovascular, nephrological, nutritional, and other medical fields. Capsaicin exerts its actions thanks to the bond with transient receptor potential vanilloid subtype 1 (TRPV1). TRPV1 is a nociceptive receptor, and its activation starts with a neurosensitive impulse, responsible for a burning pain sensation. However, constant local application of Capsaicin desensitized neuronal cells and leads to relief from neuropathic pain. In this review, we analyze the potential adjuvant role of Capsaicin in the treatment of different pathological conditions either in internal medicine or dentistry. Moreover, we present our experience in five patients affected by oro-facial pain consequent to post-traumatic trigeminal neuropathy, not responsive to any remedy, and successfully treated with topical application of Capsaicin. The topical application of Capsaicin is safe, effective, and quite tolerated by patients. For these reasons, in addition to the already-proven beneficial actions in the internal field, it represents a promising method for the treatment of neuropathic oral diseases

The GAPS programme at TNG LXIII. Photo-evaporating puzzle: Exploring the enigmatic nature of TOI-5398 b’s atmospheric signal

Context. Atmospheric characterisation plays a key role in the study of exoplanetary systems, giving hints about the current and past conditions of the planets. The information retrieved from the analysis of pivotal lines such as the Hα and He I triplet allow us to constrain the evolutionary path of the planets due to atmospheric photo-evaporation. After focussing for many years on ultra-hot Jupiters, atmospheric characterisation is slowly moving towards smaller and colder planets, which are harder to study due to the difficulties in extracting the planetary signal and which require more precise analysis. Aims. We aim to characterise the atmosphere of TOI-5398 b (P ~ 10.59 days), the outer warm Saturn orbiting a young (~650 Myr) G-type star that also hosts the small inner planet TOI-5398 c (P ~ 4.77 days). Both planets are suitable for atmospheric probing due to the closeness to their host star, which results in strong photo-evaporation processes, especially the larger outer one with an estimated transmission spectroscopy metric of 288 (higher than those of several well-known hot Jupiters). Methods. We investigated the atmosphere of planet b, analysing the data collected during a transit with HARPS-N and GIANO-B high-resolution spectrographs, employing both cross-correlation and single-line analysis to study the presence of atomic species. Incidentally, we recorded the simultaneous transit of planet c, and hence we also focussed on discerning the origin of the signal. We expect planet b to be the cause of the detected signal, since, according to existing evaporation models, it is currently expected to lose more mass than planet c. Results. We detected the presence of Hα and He I triplets, two markers of the photo-evaporation processes predicted for the system, retrieving a height in the atmosphere of 2.33 Rp and 1.65 Rp, respectively. We confirmed these predictions by employing the models computed with the ATES software, which predict a He I absorption arising from planet b comparable with the observed one. Moreover, the ATES models suggested an He/H ratio of 1/99 to match our observations. The investigation of atomic species led to the detection of an Na I doublet via single-line analysis, while the cross-correlation did not return a detection for any of the atomic species investigated

The GAPS Programme at TNG : LV. Multiple molecular species in the atmosphere of HAT-P-11 b and review of the HAT-P-11 planetary system

Context. The atmospheric characterisation of hot and warm Neptune-size exoplanets is challenging mainly due to their relatively small radius and atmospheric scale height, which reduce the amplitude of atmospheric spectral features. The warm-Neptune HAT-P-11 b is a remarkable target for atmospheric characterisation because of the large brightness of its host star (V = 9.46 mag; H = 7.13 mag). Aims: The aims of this work are to review the main physical and architectural properties of the HAT-P-11 planetary system, and to probe the presence of eight molecular species in the atmosphere of HAT-P-11 b through near-infrared (NIR) high-resolution transmission spectroscopy. Methods: We reviewed the physical and architectural properties of the HAT-P-11 planetary system by analysing transits and occultations of HAT-P-11 b from the Kepler data set as well as HIRES at Keck archival radial-velocity data. We modelled the latter with Gaussian-process regression and a combined quasi-periodic and squared-exponential kernel to account for stellar variations on both (short-term) rotation and (long-term) activity-cycle timescales. In order to probe the atmospheric composition of HAT-P-11 b, we observed four transits of this target with the NIR GIANO-B at TNG spectrograph and cross-correlated the data with template atmospheric transmission spectra. Results: We find that the long-period radial-velocity signal previously attributed to the HAT-P-11 c planet (P ~ 9.3 yr; Mp sin i ~ 1.6 MJ; e ~ 0.6) is more likely due to the stellar magnetic activity cycle. Nonetheless, the HIPPARCOS-Gaia difference in the proper-motion anomaly suggests that an outer-bound companion might still exist. For HAT-P-11 b, we measure a radius of Rp = 0.4466 ± 0.0059 RJ, a mass of Mp = 0.0787 ± 0.0048 MJ, a bulk density of ρp = 1.172 ± 0.085 g cm−3, and an orbital eccentricity of e = 0.2577−0.0025+0.0033. These values are compatible with those from the literature. Probing its atmosphere, we detect the presence of two molecular species, H2O and NH3, with a S/N of 5.1 and 5.3, and a significance of 3.4 σ and 5.0 σ, respectively. We also tentatively detect the presence of CO2 and CH4, with a S/N of 3.0 and 4.8, and a significance of 3.2 σ and 2.6 σ, respectively. Conclusions: We revisit the HAT-P-11 planetary system, confirm the presence of H2O, and report the detection of NH3 in the atmosphere of HAT-P-11 b, also finding hints for the presence of CO2 and CH4 that need to be confirmed by further observations

The GAPS Programme at TNG XXXVI. Measurement of the Rossiter-McLaughlin effect and revising the physical and orbital parameters of the HAT-P-15, HAT-P-17, HAT-P-21, HAT-P-26, HAT-P-29 eccentric planetary systems

Context. The measurement of the spin-orbit alignment of hot Jupiters, including a range of orbital and physical properties, can provide information about the evolution of the orbits of this special class of giant planets.Aims. We aim to refine the orbital and physical parameters and determine the sky-projected planet orbital obliquity ? of five eccentric (e ? 0.1–0.3) transiting planetary systems: HAT-P-15, HAT-P-17, HAT-P-21, HAT-P-26, and HAT-P-29, whose parent stars have an effective temperature between 5100 K < Teff < 6200 K. Each of the systems hosts a hot Jupiter, except for HAT-P-26, which hosts a Neptune-mass planet.Methods. We observed transit events of these planets with the HARPS-N spectrograph, obtaining high-precision radial velocity measurements that allow us to measure the Rossiter–McLaughlin effect for each of the target systems. We used these new HARPS-N spectra and archival data, including those from Gaia, to better characterise the stellar atmospheric parameters. The photometric parameters for four of the hot Jupiters were recalculated using 17 new transit light curves, obtained with an array of medium-class telescopes, and data from the TESS space telescope. HATNet time-series photometric data were checked for the signatures of rotation periods of the target stars and their spin axis inclination.Results. From the analysis of the Rossiter-McLaughlin effect, we derived a sky-projected obliquity of ? = 13° ± 6°, ? = -26.3° ± 6.7°, ? = -0.7° ± 12.5°, ? = -26° ± 16°, for HAT-P-15 b, HAT-P-17 b, HAT-P-21 b, and HAT-P-29 b, respectively. Based on theoretical considerations, these small values of ? should be of primordial origin, with the possible exception of HAT-P-21. Due to the quality of the data, we were not able to fully constrain ? for HAT-P-26 b, although a prograde orbit is favoured (? = 18° ± 49°). The stellar activity of HAT-P-21 indicates a rotation period of 15.88 ± 0.02 days, which allowed us to determine its true misalignment angle ? = 25° ± 16°. Our new analysis of the physical parameters of the five exoplanetary systems returned values compatible with those existing in the literature. Using TESS and the available transit light curves, we reviewed the orbital ephemeris for the five systems and confirmed that the HAT-P-26 system shows transit timing variations, which may tentatively be attributed to the presence of a third body

Study of the doubly charmed tetraquark T+cc

Quantum chromodynamics, the theory of the strong force, describes interactions of coloured quarks and gluons and the formation of hadronic matter. Conventional hadronic matter consists of baryons and mesons made of three quarks and quark-antiquark pairs, respectively. Particles with an alternative quark content are known as exotic states. Here a study is reported of an exotic narrow state in the D0D0π+ mass spectrum just below the D*+D0 mass threshold produced in proton-proton collisions collected with the LHCb detector at the Large Hadron Collider. The state is consistent with the ground isoscalar T+cc tetraquark with a quark content of ccu⎯⎯⎯d⎯⎯⎯ and spin-parity quantum numbers JP = 1+. Study of the DD mass spectra disfavours interpretation of the resonance as the isovector state. The decay structure via intermediate off-shell D*+ mesons is consistent with the observed D0π+ mass distribution. To analyse the mass of the resonance and its coupling to the D*D system, a dedicated model is developed under the assumption of an isoscalar axial-vector T+cc state decaying to the D*D channel. Using this model, resonance parameters including the pole position, scattering length, effective range and compositeness are determined to reveal important information about the nature of the T+cc state. In addition, an unexpected dependence of the production rate on track multiplicity is observed