2,088 research outputs found
The Fallible Phallus: A discourse analysis of male sexuality in a South African men’s interest magazine
This article presents a discourse analysis of the constructions of male sexuality in the South African
publication Men’s Health. The focus of the analysis was a series of monthly featured articles on
best sexual practices and behaviour. Since the magazine’s content appears to confront men with,
on the one hand, the construction of the ideal, potent phallus, and, on the other hand, the fallibility
inherent in attempting to live up to this ideal, the overarching discourse in the texts was termed the
‘Fallible Phallus’. By stipulating ideal sexual experiences and then juxtaposing these descriptions
with the threat of those moments not occurring, a paradox is created in the texts between the phallic
dominance of masculinity and the anxieties and insecurities that may result from sexual failure. The
Fallible Phallus discourse is a synthesis of four subsidiary themes derived from the texts, namely the
male sexual drive theme, the inadequacies of male sexuality, the rule book of sexual practices, and
the problematic nature of female sexuality. In the discussion of these themes, it is suggested that the
texts use male sexual performance as a yardstick for assessing level of masculinity
Selection Of Independent Binary Features Using Probabilities: An Example From Veterinary Medicine
Supervised classification into c mutually exclusive classes based on n binary features is considered. The only information available is an n×c table with probabilities. Knowing that the best d features are not the d best, simulations were run for 4 feature selection methods and an application to diagnosing BSE in cattle and Scrapie in sheep is presented
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Vitamin D intake and risk of CVD and all-cause mortality: evidence from the Caerphilly Prospective Cohort Study
OBJECTIVE:
Prospective data on the associations between vitamin D intake and risk of CVD and all-cause mortality are limited and inconclusive. The aim of the present study was to investigate the associations between vitamin D intake and CVD risk and all-cause mortality in the Caerphilly Prospective Cohort Study.
DESIGN:
The associations of vitamin D intake with CVD risk markers were examined cross-sectionally at baseline and longitudinally at 5-year, 10-year and >20-year follow-ups. In addition, the predictive value of vitamin D intake for CVD events and all-cause mortality after >20 years of follow-up was examined. Logistic regression and general linear regression were used for data analysis.
SETTING:
Participants in the UK.
SUBJECTS:
Men (n 452) who were free from CVD and type 2 diabetes at recruitment.
RESULTS:
Higher vitamin D intake was associated with increased HDL cholesterol (P=0·003) and pulse pressure (P=0·04) and decreased total cholesterol:HDL cholesterol (P=0·008) cross-sectionally at baseline, but the associations were lost during follow-up. Furthermore, higher vitamin D intake was associated with decreased concentration of plasma TAG at baseline (P=0·01) and at the 5-year (P=0·01), but not the 10-year examination. After >20 years of follow-up, vitamin D was not associated with stroke (n 72), myocardial infarctions (n 142), heart failure (n 43) or all-cause mortality (n 281), but was positively associated with increased diastolic blood pressure (P=0·03).
CONCLUSIONS:
The study supports associations of higher vitamin D intake with lower fasting plasma TAG and higher diastolic blood pressure
Mathematically gifted and talented learners: Theory and practice
This is an Author's Accepted Manuscript of an article published in International Journal of Mathematical Education in Science and Technology, 40(2), 213-228, 2009, copyright Taylor & Francis, available online at: http://www.tandfonline.com/10.1080/00207390802566907.There is growing recognition of the special needs of mathematically gifted learners. This article reviews policy developments and current research and theory on giftedness in mathematics. It includes a discussion of the nature of mathematical ability as well as the factors that make up giftedness in mathematics. The article is set in the context of current developments in Mathematics Education and Gifted Education in the UK and their implications for Science and Technology. It argues that early identification and appropriate provision for younger mathematically promising pupils capitalizes on an intellectual resource which could provide future mathematicans as well as specialists in Science or Technology. Drawing on a Vygotskian framework, it is suggested that the mathematically gifted require appropriate cognitive challenges as well as attitudinally and motivationally enhancing experiences. In the second half of this article we report on an initiative in which we worked with teachers to identify mathematically gifted pupils and to provide effective enrichment support for them, in a number of London Local Authorities. A number of significant issues are raised relating to the identification of mathematical talent, enrichment provision for students and teachers’ professional development
Effect of Arteriovenous Anastomosis on Blood Pressure Reduction in Patients With Isolated Systolic Hypertension Compared With Combined Hypertension
Background: Options for interventional therapy to lower blood pressure (BP) in
patients with treatment‐resistant hypertension include renal denervation and
the creation of an arteriovenous anastomosis using the ROX coupler. It has
been shown that BP response after renal denervation is greater in patients
with combined hypertension (CH) than in patients with isolated systolic
hypertension (ISH). We analyzed the effect of ROX coupler implantation in
patients with CH as compared with ISH. Methods and Results: The randomized,
controlled, prospective ROX Control Hypertension Study included patients with
true treatment‐resistant hypertension (office systolic BP ≥140 mm Hg, average
daytime ambulatory BP ≥135/85 mm Hg, and treatment with ≥3 antihypertensive
drugs including a diuretic). In a post hoc analysis, we stratified patients
with CH (n=31) and ISH (n=11). Baseline office systolic BP (177±18 mm Hg
versus 169±17 mm Hg, P=0.163) and 24‐hour ambulatory systolic BP (159±16 mm Hg
versus 154±11 mm Hg, P=0.463) did not differ between patients with CH and
those with ISH. ROX coupler implementation resulted in a significant reduction
in office systolic BP (CH: −29±21 mm Hg versus ISH: −22±31 mm Hg, P=0.445) and
24‐hour ambulatory systolic BP (CH: −14±20 mm Hg versus ISH: −13±15 mm Hg,
P=0.672), without significant differences between the two groups. The
responder rate (office systolic BP reduction ≥10 mm Hg) after 6 months was not
different (CH: 81% versus ISH: 82%, P=0.932). Conclusions: Our data suggest
that creation of an arteriovenous anastomosis using the ROX coupler system
leads to a similar reduction of office and 24‐hour ambulatory systolic BP in
patients with combined and isolated systolic hypertension. Clinical Trial
Registration: URL: http://www.clinicaltrials.gov. Unique identifier:
NCT01642498
Newly Identified Star Clusters in M33. III. Structural Parameters
We present the morphological properties of 161 star clusters in M33 using the
Advanced Camera For Surveys Wide Field Channel onboard the Hubble Space
Telescope using observations with the F606W and F814W filters. We obtain, for
the first time, ellipticities, position angles, and surface brightness profiles
for a significant number of clusters. On average, M33 clusters are more
flattened than those of the Milky Way and M31, and more similar to clusters in
the Small Magellanic Cloud. The ellipticities do not show any correlation with
age or mass, suggesting that rotation is not the main cause of elongation in
the M33 clusters. The position angles of the clusters show a bimodality with a
strong peak perpendicular to the position angle of the galaxy major axis. These
results support the notion that tidal forces are the reason for the cluster
flattening. We fit King and EFF models to the surface brightness profiles and
derive structural parameters including core radii, concentration, half-light
radii and central surface brightness for both filters. The surface brightness
profiles of a significant number of clusters show irregularities such as bumps
and dips. Young clusters (Log age < 8) are notably better fitted by models with
no radial truncation (EFF models), while older clusters show no significant
differences between King or EFF fits. M33 star clusters seem to have smaller
sizes, smaller concentrations, and smaller central surface brightness as
compared to clusters in the MW, M31, LMC and SMC. Analysis of the structural
parameters presents a age-radius relation also detected in other star cluster
systems. The overall analysis shows differences in the structural evolution
between the M33 cluster system and cluster systems in nearby galaxies. These
differences could have been caused by the strong differences in these various
environments.Comment: 30 pages, 12 figures, accepted for publication in MNRA
Methods for evaluating endothelial function: a position statement from the European Society of Cardiology Working Group on Peripheral Circulation
The endothelium holds a pivotal role in cardiovascular health and disease. Assessment of its function was until recently limited to experimental designs due to its location. The advent of novel techniques has facilitated testing on a more detailed basis, with focus on distinct pathways. This review presents available in-vivo and ex-vivo methods for evaluating endothelial function with special focus on more recent ones. The diagnostic modalities covered include assessment of epicardial and microvascular coronary endothelial function, local vasodilation by venous occlusion plethysmography and flow-mediated dilatation, arterial pulse wave analysis and pulse amplitude tonometry, microvascular blood flow by laser Doppler flowmetry, biochemical markers and bioassays, measurement of endothelial-derived microparticles and progenitor cells, and glycocalyx measurements. Insights and practical information on the theoretical basis, methodological aspects, and clinical application in various disease states are discussed. The ability of these methods to detect endothelial dysfunction before overt cardiovascular disease manifests make them attractive clinical tools for prevention and rehabilitation
The Importance of Context and Cognitive Agency in Developing Police Knowledge: Going Beyond the Police Science Discourse
This paper argues the current exposition of police knowledge through the discourses of police science and evidenced based policing (EBP) leads to exaggerated claims about what is, and can be, known in policing. This new orthodoxy underestimates the challenges of applying knowledge within culturally-mediated police practice. The paper draws upon virtue epistemology highlighting the role cognitive agency plays in establishing knowledge claims. We challenge the assumption that it is possible to derive what works in all instances of certain aspects of policing and suggest it would be more apt to speak about what worked within a specific police context
Risk factors for metabolic syndrome independently predict arterial stiffness and endothelial dysfunction in patients with chronic kidney disease and minimal comorbidity
OBJECTIVE: Metabolic syndrome (MS) is common in patients with chronic kidney disease (CKD), but its contribution to arterial stiffness and endothelial dysfunction in CKD is not well defined. We hypothesized that risk factors for MS would independently predict arterial stiffness and endothelial dysfunction in CKD patients. RESEARCH DESIGN AND METHODS: Risk factors for MS, carotid-femoral pulse wave velocity (CF-PWV) and flow-mediated dilation (FMD) as measures of arterial stiffness and endothelial dysfunction, respectively, were assessed in 113 minimally comorbid CKD patients and in 23 matched control subjects. RESULTS: CF-PWV correlated with systolic blood pressure (SBP), waist circumference, and plasma glucose (r(2) = 0.25, 0.09, and 0.09; P < 0.01 for all). FMD correlated with SBP (r(2) = 0.09; P < 0.01) and waist circumference (r(2) = 0.03; P < 0.05). CF-PWV increased progressively (r(2) = 0.07; P < 0.01) with increasing number of risk factors for MS. In multiple linear regression, SBP and waist circumference were independent determinants of CF-PWV, whereas only SBP predicted FMD. CONCLUSIONS: The number of MS risk factors is an important determinant of arterial stiffness in CKD patients irrespective of the degree of renal impairment. Although BP remains the major determinant of arterial stiffness and endothelial dysfunction, waist circumference independently predicts arterial stiffness. MS risk factors, particularly abdominal girth, are potential targets for future interventional studies in patients with CKD
What constitutes responsiveness of physicians: A qualitative study in rural Bangladesh
Responsiveness entails the social actions by health providers to meet the legitimate expectations
of patients. It plays a critical role in ensuring continuity and effectiveness of care
within people centered health systems. Given the lack of contextualized research on
responsiveness, we qualitatively explored the perceptions of outpatient users and providers
regarding what constitute responsiveness in rural Bangladesh. An exploratory study was
undertaken in Chuadanga, a southwestern Bangladeshi District, involving in-depth interviews
of physicians (n = 17) and users (n = 7), focus group discussions with users (n = 4),
and observations of patient provider interactions (three weeks). Analysis was guided by a
conceptual framework of responsiveness, which includes friendliness, respecting, informing
and guiding, gaining trust and optimizing benefits. In terms of friendliness, patients expected
physicians to greet them before starting consultations; even though physicians considered
this unusual. Patients also expected physicians to hold social talks during consultations,
which was uncommon. With regards to respect patients expected physicians to refrain from
disrespecting them in various ways; but also by showing respect explicitly. Patients also had
expectations related to informing and guiding: they desired explanation on at least the diagnosis,
seriousness of illness, treatment and preventive steps. In gaining trust, patients
expected that physicians would refrain from illegal or unethical activities related to patients,
e.g., demanding money against free services, bringing patients in own private clinics by brokers
(dalals), colluding with diagnostic centers, accepting gifts from pharmaceutical representatives.
In terms of optimizing benefits: patients expected that physicians should be
financially sensitive and consider individual need of patients. There were multiple dimensions
of responsiveness- for some, stakeholders had a consensus; context was an important
factor to understand them. This being an exploratory study, further research is
recommended to validate the nuances of the findings. It can be a guideline for responsiveness
practices, and a tipping point for future research
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