61 research outputs found
Optimization of facade design based on the impact of interior obstructions to daylighting
Overcrowding in the perimeter zone is an inevitable issue in residential rooms with limited space. Obstructions, such as furniture and household items, may block the existing windows, and therefore affect interior daylight conditions. A facade design approach is needed that simultaneously takes into account daylighting and the volume of usable space for obstructions in the perimeter zone of such rooms. This study simulates daylight distributions in a typical small residential room with obstructions in front of windows. The simulation consists of two parts. First, the effects on horizontal illuminances caused by different positions and shapes of obstructions are examined under an overcast sky. Second, the maximum usable space volumes for obstructions of 51 optimized facade configurations are calculated in terms of four window-to-wall ratios (WWRs). The results of this study show that optimizing the forms of facade design can increase the usable interior space volume and meet the daylighting requirements of Chinese standards for small residential rooms. Additionally, by using the optimized facade forms, a facade with a WWR value of 50% provides the maximum usable space for obstructions. Based on the above results, this paper presents two matrices that can help architects in selecting the appropriate fenestration methods and confirming the size of usable space and allocation for residents
Brain energy rescue:an emerging therapeutic concept for neurodegenerative disorders of ageing
The brain requires a continuous supply of energy in the form of ATP, most of which is produced from glucose by oxidative phosphorylation in mitochondria, complemented by aerobic glycolysis in the cytoplasm. When glucose levels are limited, ketone bodies generated in the liver and lactate derived from exercising skeletal muscle can also become important energy substrates for the brain. In neurodegenerative disorders of ageing, brain glucose metabolism deteriorates in a progressive, region-specific and disease-specific manner — a problem that is best characterized in Alzheimer disease, where it begins presymptomatically. This Review discusses the status and prospects of therapeutic strategies for countering neurodegenerative disorders of ageing by improving, preserving or rescuing brain energetics. The approaches described include restoring oxidative phosphorylation and glycolysis, increasing insulin sensitivity, correcting mitochondrial dysfunction, ketone-based interventions, acting via hormones that modulate cerebral energetics, RNA therapeutics and complementary multimodal lifestyle changes
Correlating Indian measured sky luminance distribution and Indian Design clear sky model with five CIE Standard clear sky models
Estimation of average daylight factor under obstructed CIE Standard General Skies
Recently, the CIE has adopted a range of 15 standard sky distributions covering the whole spectrum of usual skies found in nature. In a dense urban region, the external environment plays a significant role in daylighting designs. This paper studies an approach to calculating the average daylight factor for rooms facing heavily obstructed environments under overcast and non-overcast skies. The modelled vertical sky components under the various unobstructed and obstructed CIE Standard General Skies were determined. The performance of the proposed method was evaluated against the results obtained by computer simulations. The proposed approach provides a simple alternative for comparing daylighting designs for buildings facing different obstructed environments under various sky conditions. </jats:p
FFP<sub>3</sub>, FFP<sub>2</sub>, N<sub>95</sub>, surgical masks and respirators: what should we be wearing for ophthalmic surgery in the COVID-19 pandemic?
Life-cycle analysis of photovoltaic systems in Hong Kong
202502 bcchVersion of RecordRGCOthersCity University of Hong Kong studentshipPublishedVoR allowe
Evaluation of a Simple Method for Determining the Vertical Daylight Factor against Full-Scale Measured Data
Genome-wide Expression Profiling Reveals the Multiple Signaling Pathways Modulated by rAdv-hTERTC27 Treatment in Glioblastoma Multiforme
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