FPGA based remote code integrity verification of programs in distributed embedded systems

The explosive growth of networked embedded systems has made ubiquitous and pervasive computing a reality. However, there are still a number of new challenges to its widespread adoption that include scalability, availability, and, especially, security of software. Among the different challenges in software security, the problem of remote-code integrity verification is still waiting for efficient solutions. This paper proposes the use of reconfigurable computing to build a consistent architecture for generation of attestations (proofs) of code integrity for an executing program as well as to deliver them to the designated verification entity. Remote dynamic update of reconfigurable devices is also exploited to increase the complexity of mounting attacks in a real-word environment. The proposed solution perfectly fits embedded devices that are nowadays commonly equipped with reconfigurable hardware components that are exploited to solve different computational problems

Il censimento delle strade appartenenti alla rete extraurbana: aspetti metodologici e normativi

La mancata classificazione della rete comporta da un lato la quasi impossibile realizzazione dei Piani del Traffico della Viabilità Extraurbana (PTVE) e dall???altro determina la quasi impossibile definizione delle priorità in termini di manutenzione e ottimizzazione delle infrastrutture esistenti. A questi si aggiungono altri due aspetti: le Amministrazioni sono chiamate a perseguire l???innalzamento dei livelli di sicurezza stradale e dall???altro lato devono assicurare la totale accessibilità dei territori, il tutto in un contesto di totale contenimento della spesa

Achieving the Way for Automated Segmentation of Nuclei in Cancer Tissue Images through Morphology-Based Approach: a Quantitative Evaluation

In this paper we address the problem of nuclear segmentation in cancer tissue images, that is critical for specific protein activity quantification and for cancer diagnosis and therapy. We present a fully automated morphology-based technique able to perform accurate nuclear segmentations in images with heterogeneous staining and multiple tissue layers and we compare it with an alternate semi-automated method based on a well established segmentation approach, namely active contours. We discuss active contours’ limitations in the segmentation of immunohistochemical images and we demonstrate and motivate through extensive experiments the better accuracy of our fully automated approach compared to various active contours implementations

The current progress of the ALICE Ring Imaging Cherenkov Detector

Recently, the last two modules (out of seven) of the ALICE High Momentum Particle Identification detector (HMPID) were assembled and tested. The full detector, after a pre-commissioning phase, has been installed in the experimental area, inside the ALICE solenoid, at the end of September 2006. In this paper we review the status of the ALICE/HMPID project and we present a summary of the series production of the CsI photo-cathodes. We describe the key features of the production procedure which ensures high quality photo-cathodes as well as the results of the quality assessment performed by means of a specially developed 2D scanner system able to produce a detailed map of the CsI photo-current over the entire photo-cathode surface. Finally we present our recent R&D efforts toward the development of a novel generation of imaging Cherenkov detectors with the aim to identify, in heavy ions collisions, hadrons up to 30 GeV/c.Comment: Presented at the Imaging-2006 Conference, Stockholm, Sweden, June 200

Bianchi Type I Universes with Causal Bulk Viscous Cosmological Fluid

We consider the dynamics of a causal bulk viscous cosmological fluid filled constantly decelerating Bianchi type I space-time. The matter component of the Universe is assumed to satisfy a linear barotropic equation of state and the state equation of the small temperature Boltzmann gas. The resulting cosmological models satisfy the condition of smallness of the viscous stress. The time evolution of the relaxation time, temperature, bulk viscosity coefficient and comoving entropy of the dissipative fluid is also obtained.Comment: 11 pages, 5 figures, accepted for publication in International Journal of Modern Physics

Automated segmentation of tissue images for computerized IHC analysis

This paper presents two automated methods for the segmentation ofimmunohistochemical tissue images that overcome the limitations of themanual approach aswell as of the existing computerized techniques. The first independent method, based on unsupervised color clustering, recognizes automatically the target cancerous areas in the specimen and disregards the stroma; the second method, based on colors separation and morphological processing, exploits automated segmentation of the nuclear membranes of the cancerous cells. Extensive experimental results on real tissue images demonstrate the accuracy of our techniques compared to manual segmentations; additional experiments show that our techniques are more effective in immunohistochemical images than popular approaches based on supervised learning or active contours. The proposed procedure can be exploited for any applications that require tissues and cells exploration and to perform reliable and standardized measures of the activity of specific proteins involved in multi-factorial genetic pathologie

MLL-MLLT10 fusion in acute monoblastic leukemia: variant complex rearrangements and 11q proximal breakpoint heterogeneity

Cytogenetic studies of acute monoblastic leukemia cases presenting MLL-MLLT10 (alias MLL-AF10) fusion show a broad heterogeneity of chromosomal breakpoints. We present two new pediatric cases (French-American-British type M5) with MLL-MLLT10 fusion, which we studied with fluorescence in situ hybridization. In both we detected a paracentric inversion of the 11q region that translocated onto chromosome 10p12; one case displayed a variant complex pattern. We review the cytogenetic molecular data concerning the proximal inversion breakpoint of 11q and confirm its heterogeneit

Type III pleuropulmonary blastoma in a 7-month-old female baby with impending respiratory failure: a case report

INTRODUCTION: Pleuropulmonary blastoma is a very rare, aggressive, embryonal pulmonary neoplasm which mostly affects children under the age of 5. According to the histopathological features, three subtypes of pleuropulmonary blastoma have been recognized: type I (purely cystic), type II (grossly visible cystic and solid elements) and type III (purely solid). Characteristics of type I and type II blastoma allow an earlier diagnosis compared with type III. Here we present a case report of an unusual presentation of type III pleuropulmonary blastoma. CASE PRESENTATION: We describe the case of a 7-month-old female baby of Italian mother and Kurdish father who was diagnosed with type III pleuropulmonary blastoma, which entirely occupied her right hemithorax. CONCLUSIONS: The reported case is an unusual presentation because type III pleuropulmonary blastoma typically occurs in older children. The complete re-expansion of her residual, previously totally compressed, right lung observed immediately after the resection of the lesion suggests an atypical rapid growth of this embryonal tumor in the late phase of gestation or after delivery. This case report suggests that, in addition to other childhood tumors, type III pleuropulmonary blastoma should be included in the differential diagnosis of solid nonhomogeneous thoracic large masses, compressing the mediastinal and chest wall structures in infants. This is an original case report of interest for several specialities such us pediatrics, radiology, surgery and oncology

The Integrated HV, LV and Liquid Radiator Control System for the HMPID in the ALICE Experiment at LHC

The complexity and the underground location of the new generation experiments (ALICE, ATLAS, CMS and LHCb) at the CERN Large Hadron Collider (LHC) requires a reliable and user friendly control system to operate such large detectors remotely. Control system experts at CERN are deeply involved in developing the JCOP (Joint Controls Project) 'Framework', a software running in the PVSSII SCADA1 (Supervisory Control And Data Acquisition) system, that will provide a homogeneous and ready to use tool for the control system developers of the LHC experiments. The High Momentum Particle Identification Detector (HMPID), one of the ALICE2 sub-detectors, is being equipped with a Detector Control System (DCS) developed within the JCOP Framework. In this paper the basic features and the first results of the DCS prototype are presented

Clostridium difficile infection in Italian urban hospitals: data from 2006 through 2011

BACKGROUND: In developed countries, Clostridium difficile infection (CDI) represents an emerging threat in terms of morbidity and mortality rates. In our country limited CDI epidemiological data can be found. We have conducted a 6-year retrospective study to evaluate the incidence of CDI in Italian urban hospitals. METHODS: Stool samples tested for C. difficile toxins from January 2006 to December 2011 in 5 large hospitals in Rome, Italy, were considered in the analysis. Repeated samples taken ≤ 2 months after a positive result were excluded. RESULTS: A total of 402 CDI episodes were identified. The incidence of CDI episodes progressively increased from 0.3 in 2006 to 2.3 per 10,000 patient-days in 2011. CDI episodes mostly occurred in patients > 60 years of age (77%). The >80 year-old age class reported the highest percentage of CDI episodes on tested samples (16%). Eighty percent (80%) of CDI episodes occurred in medical wards followed by surgery (10.2%) and intensive care units (9.8%). CONCLUSIONS: A significant increasing incidence of CDI episodes over the study period was observed during the years (p<.001), particularly in the older age groups. Medical wards experienced the highest number of CDI episodes as compared to intensive care and surgical wards. The increasing rate of CDI episodes over the last six years in our country, is alarming; urgent improvements in the surveillance systems and control programs are advisable