664 research outputs found
Learning through a portfolio of carbon capture and storage demonstration projects
Carbon dioxide capture and storage (CCS) technology is considered by many to be an essential route to meet climate mitigation targets in the power and industrial sectors. Deploying CCS technologies globally will first require a portfolio of large-scale demonstration projects. These first projects should assist learning by diversity, learning by replication, de-risking the technologies and developing viable business models. From 2005 to 2009, optimism about the pace of CCS rollout led to mutually independent efforts in the European Union, North America and Australia to assemble portfolios of projects. Since 2009, only a few of these many project proposals remain viable, but the initial rationales for demonstration have not been revisited in the face of changing circumstances. Here I argue that learning is now both more difficult and more important given the slow pace of deployment. Developing a more coordinated global portfolio will facilitate learning across projects and may determine whether CCS ever emerges from the demonstration phase.
Economic models deem rapid wide-scale deployment of CCS in the next few years to be essential in restraining the costs of meeting the 2 °C target for global temperature1,2, but CCS technologies are still at the pilot and demonstration phase. Paradoxically, it is primarily the costs of the early demonstration projects that have hampered further deployment. As each CCS ‘demonstration’ plant costs on the order of US$1 billion, during a time of fiscal austerity it has proved difficult to justify public support. Near-term pressure to develop CCS has also eased as most countries found it easier to meet their Kyoto targets because of the economic crisis (and other factors such as the US shale gas revolution). Meanwhile, unlocking private financing remains elusive and depends on developing necessary legal, institutional and commercial frameworks, as well as significant cost reductions and de-risking that can only come from operating multiple plants3.
Difficulties in justifying pilot and demonstration plants or deployment policy are hardly restricted to CCS, and can be found for nuclear power, renewables and indeed virtually any novel technology4,5, but the emphasis on demonstration is most common in the process industries6. At its broadest, CCS ‘demonstration’ has been identified as having a dozen or more manifestations, ranging from discourse creation to coalition formation7. I acknowledge the many important dimensions of demonstration, indeed, different disciplines have radically different conceptions of the nature of demonstration6. Given the overwhelming government and industry focus on cost reduction8,9, however, I use this as a test of how learning is operationalized. Governments should at least be able to construct a portfolio of projects along the dimension that they deem as central to the enterprise of demonstration.
The technical rationales for demonstrations being large-scale include understanding power system reliability and performance10 and adequately characterizing each geological formation11. As large-scale projects must store roughly 1 million tCO2 per year10,11, this scale requirement poses a number of challenges when seeking to learn from multiple projects.
In this Perspective, I explore the history of CCS demonstration in an effort to understand how the initial optimism about large-scale rollout led to multiple, uncoordinated efforts to learn from diversity. In the absence of widespread deployment of CCS, the projects that have endured do not form a coherent programme aimed at learning. Going forward, therefore, any effort to successfully re-launch CCS at scale will need to revisit the fundamental case for demonstration, including how best to derive the most learning from the billions of dollars already invested and that will need to be invested in the next wave of projects. There is a need for greater clarity over what time frame, at what scale, at what cost and to what end CCS demonstration is being pursued
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Evaluating gaps in knowledge, willingness and heating performance in individual preferences on household energy and climate policy: evidence from the UK
This study investigates the knowledge-willingness, willingness-performance, and knowledge-performance gaps regarding reducing carbon dioxide emissions and emerging technologies of the 2137 British residents. Household's heating sources and heat settings are anticipated as key criteria for evaluating respondents' performances. The study revealed more than 80% of respondents have a good knowledge regarding climate change and carbon issues. The study found a smaller gap in knowledge versus willingness as 59%, 87%, 88% and 85% of respondents want to use bioenergy, afforestation/reforestation, solar and wind for their future energy sources. The Multinomial logit regression (MNLR) investigates that incrementing good and very good knowledge index increases the odds of a high willingness to save energy by 33% and 6%, respectively. The willingness versus performance study identified 96% as claiming to be more likely energy savers, whereas, in reality, 52% of them never or rarely took basic measures like setting their heating system to turn off. Despite having a good and very good knowledge index, the knowledge versus performance appears, 75% of respondents are using gas boilers and gas central heating. Policymakers and the research community need to develop comprehensive plans by taking these wider social issues to meet net-zero targets. Employing smart building principles, lowering the installation costs of the new smart technologies, awarding and encouraging the energy saver, setting individual carbon footprint limits, and training and empowering household representatives to select better energy for houses could popularise the emission reduction technologies in the UK.Fortumin Foundation provided financial support as a grant to TK to visit Cambridge and carry out the research. The grant number was 201800255. The YouGov survey was supported by the UK Engineering and Physical Sciences Research Council (EPSRC) grant EP/P02614/
Evolution in inter-firm governance along the transport biofuel value chain in maritime Silk Road countries
We investigate how value chain governance can evolve in the transport biofuel sector beyond logistics and operations optimization, drawing on cases of eighteen manufacturers in four Belt and Road countries. We find that key motivations for vertical integration include control of strategic factors such as security of supply and gaining access to the retail market, subject to inter-institutional and intra-organizational barriers. We contribute to a theory of governance mode selection by suggesting plural governance mode offers a key strategic choice under institutional constraints. In BRI countries, plural mode could be less disruptive when integrating value chains.ESRC-Cambridge Commonwealth Trust-Dorothy Hodgkin Postgraduate Awar
Economics and politics of shale gas in Europe
In the wake of the dramatic growth in shale gas production in the United States, interest in shale gas exploration in Europe has been driven primarily by concerns over industrial competitiveness and energy security. A number of studies have been carried out to understand the success factors underpinning the US shale gas revolution and how this success could be replicated in Europe. Most of these studies focus on the macroeconomic and energy market impact of a possible shale gas production in Europe. These studies are in general sceptical about the prospects of shale gas development relative to other gas supply options to Europe. By considering the other options available in greater detail and exploring the stochastic nature of shale gas exploration and production as they apply to production economics, we conclude that this scepticism may be overstated. Apart from political opposition that has shut down shale gas exploration in a number of European member states because of concerns over environmental risks, in some countries notably the UK, the combination of political support and a large, liberalised gas market may offer at least a plausible case for shale gas production. To properly assess the potential for shale gas though, a more rigorous, probabilistic analysis of the associated production economics will need to be carried out
Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms
Coronary artery disease (CAD) is a leading cause of morbidity and mortality worldwide. Although 58 genomic regions have been associated with CAD thus far, most of the heritability is unexplained, indicating that additional susceptibility loci await identification. An efficient discovery strategy may be larger-scale evaluation of promising associations suggested by genome-wide association studies (GWAS). Hence, we genotyped 56,309 participants using a targeted gene array derived from earlier GWAS results and performed meta-analysis of results with 194,427 participants previously genotyped, totaling 88,192 CAD cases and 162,544 controls. We identified 25 new SNP-CAD associations (P < 5 × 10(-8), in fixed-effects meta-analysis) from 15 genomic regions, including SNPs in or near genes involved in cellular adhesion, leukocyte migration and atherosclerosis (PECAM1, rs1867624), coagulation and inflammation (PROCR, rs867186 (p.Ser219Gly)) and vascular smooth muscle cell differentiation (LMOD1, rs2820315). Correlation of these regions with cell-type-specific gene expression and plasma protein levels sheds light on potential disease mechanisms
Dissemination and implementation of an educational tool for veterans on complementary and alternative medicine: a case study
Background Predicting when and where pathogens will emerge is difficult, yet, as shown by the recent Ebola and Zika epidemics, effective and timely responses are key. It is therefore crucial to transition from reactive to proactive responses for these pathogens. To better identify priorities for outbreak mitigation and prevention, we developed a cohesive framework combining disparate methods and data sources, and assessed subnational pandemic potential for four viral haemorrhagic fevers in Africa, Crimean–Congo haemorrhagic fever, Ebola virus disease, Lassa fever, and Marburg virus disease. Methods In this multistage analysis, we quantified three stages underlying the potential of widespread viral haemorrhagic fever epidemics. Environmental suitability maps were used to define stage 1, index-case potential, which assesses populations at risk of infection due to spillover from zoonotic hosts or vectors, identifying where index cases could present. Stage 2, outbreak potential, iterates upon an existing framework, the Index for Risk Management, to measure potential for secondary spread in people within specific communities. For stage 3, epidemic potential, we combined local and international scale connectivity assessments with stage 2 to evaluate possible spread of local outbreaks nationally, regionally, and internationally. Findings We found epidemic potential to vary within Africa, with regions where viral haemorrhagic fever outbreaks have previously occurred (eg, western Africa) and areas currently considered non-endemic (eg, Cameroon and Ethiopia) both ranking highly. Tracking transitions between stages showed how an index case can escalate into a widespread epidemic in the absence of intervention (eg, Nigeria and Guinea). Our analysis showed Chad, Somalia, and South Sudan to be highly susceptible to any outbreak at subnational levels. Interpretation Our analysis provides a unified assessment of potential epidemic trajectories, with the aim of allowing national and international agencies to pre-emptively evaluate needs and target resources. Within each country, our framework identifies at-risk subnational locations in which to improve surveillance, diagnostic capabilities, and health systems in parallel with the design of policies for optimal responses at each stage. In conjunction with pandemic preparedness activities, assessments such as ours can identify regions where needs and provisions do not align, and thus should be targeted for future strengthening and support
Key indicators to track current progress and future ambition of the Paris Agreement
Current emission pledges to the Paris Agreement appear insufficient to hold the global average temperature increase to well below 2 °C above pre-industrial levels. Yet, details are missing on how to track progress towards the â € Paris goal', inform the five-yearly â € global stocktake', and increase the ambition of Nationally Determined Contributions (NDCs). We develop a nested structure of key indicators to track progress through time. Global emissions track aggregated progress, country-level decompositions track emerging trends that link directly to NDCs, and technology diffusion indicates future reductions. We find the recent slowdown in global emissions growth is due to reduced growth in coal use since 2011, primarily in China and secondarily in the United States. The slowdown is projected to continue in 2016, with global CO 2 emissions from fossil fuels and industry similar to the 2015 level of 36 GtCO 2. Explosive and policy-driven growth in wind and solar has contributed to the global emissions slowdown, but has been less important than economic factors and energy efficiency. We show that many key indicators are currently broadly consistent with emission scenarios that keep temperatures below 2 °C, but the continued lack of large-scale carbon capture and storage threatens 2030 targets and the longer-term Paris ambition of net-zero emissions
Direct air capture: process technology, techno-economic and socio-political challenges
Climate change mitigation scenarios that meet the Paris Agreement's objective of limiting global warming usually assume an important role for carbon dioxide removal and negative emissions technologies. Direct air capture (DAC) is a carbon dioxide removal technology which separates CO2 directly from the air using an engineered system. DAC can therefore be used alongside other negative emissions technologies, in principle, to mitigate CO2 emissions from a wide variety of sources, including those that are mobile and dispersed. The ultimate fate of the CO2, whether it is stored, reused, or utilised, along with choices related to the energy and materials inputs for a DAC process, dictates whether or not the overall process results in negative emissions. In recent years, DAC has undergone significant technical development, with commercial entities now operating in the market and prospects for significant upscale. Here we review the state-of-the-art to provide clear research challenges across the process technology, techno-economic and socio-political domains
C-reactive protein levels in patients at cardiovascular risk: EURIKA study
Background: Elevated C-reactive protein (CRP) levels are associated with high cardiovascular risk, and might identify patients who could benefit from more carefully adapted risk factor management. We have assessed the prevalence of elevated CRP levels in patients with one or more traditional cardiovascular risk factors.
Methods: Data were analysed from the European Study on Cardiovascular Risk Prevention and Management in Usual Daily Practice (EURIKA, ClinicalTrials.gov Identifier: NCT00882336), which included patients (aged ≥50 years) from 12 European countries with at least one traditional cardiovascular risk factor but no history of cardiovascular disease. Analysis was also carried out on the subset of patients without diabetes mellitus who were not receiving statin therapy.
Results: In the overall population, CRP levels were positively correlated with body mass index and glycated haemoglobin levels, and were negatively correlated with high-density lipoprotein cholesterol levels. CRP levels were also higher in women, those at higher traditionally estimated cardiovascular risk and those with greater numbers of metabolic syndrome markers. Among patients without diabetes mellitus who were not receiving statin therapy, approximately 30% had CRP levels ≥3 mg/L, and approximately 50% had CRP levels ≥2 mg/L, including those at intermediate levels of traditionally estimated cardiovascular risk.
Conclusions: CRP levels are elevated in a large proportion of patients with at least one cardiovascular risk factor, without diabetes mellitus who are not receiving statin therapy, suggesting a higher level of cardiovascular risk than predicted according to conventional risk estimation systems
Identification, characterization, and gene expression analysis of nucleotide binding site (NB)-type resistance gene homologues in switchgrass
Abstract
Background
Switchgrass (Panicum virgatum L.) is a warm-season perennial grass that can be used as a second generation bioenergy crop. However, foliar fungal pathogens, like switchgrass rust, have the potential to significantly reduce switchgrass biomass yield. Despite its importance as a prominent bioenergy crop, a genome-wide comprehensive analysis of NB-LRR disease resistance genes has yet to be performed in switchgrass.
Results
In this study, we used a homology-based computational approach to identify 1011 potential NB-LRR resistance gene homologs (RGHs) in the switchgrass genome (v 1.1). In addition, we identified 40 RGHs that potentially contain unique domains including major sperm protein domain, jacalin-like binding domain, calmodulin-like binding, and thioredoxin. RNA-sequencing analysis of leaf tissue from ‘Alamo’, a rust-resistant switchgrass cultivar, and ‘Dacotah’, a rust-susceptible switchgrass cultivar, identified 2634 high quality variants in the RGHs between the two cultivars. RNA-sequencing data from field-grown cultivar ‘Summer’ plants indicated that the expression of some of these RGHs was developmentally regulated.
Conclusions
Our results provide useful insight into the molecular structure, distribution, and expression patterns of members of the NB-LRR gene family in switchgrass. These results also provide a foundation for future work aimed at elucidating the molecular mechanisms underlying disease resistance in this important bioenergy crop
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