Study of Bc+B_c^+ decays to the K+K−π+K^+K^-\pi^+ final state and evidence for the decay Bc+→χc0π+B_c^+\to\chi_{c0}\pi^+

A study of $B_c^+\to K^+K^-\pi^+$ decays is performed for the first time using data corresponding to an integrated luminosity of 3.0 $\mathrm{fb}^{-1}$ collected by the LHCb experiment in $pp$ collisions at centre-of-mass energies of $7$ and $8$ TeV. Evidence for the decay $B_c^+\to\chi_{c0}(\to K^+K^-)\pi^+$ is reported with a significance of 4.0 standard deviations, resulting in the measurement of $\frac{\sigma(B_c^+)}{\sigma(B^+)}\times\mathcal{B}(B_c^+\to\chi_{c0}\pi^+)$ to be $(9.8^{+3.4}_{-3.0}(\mathrm{stat})\pm 0.8(\mathrm{syst}))\times 10^{-6}$. Here $\mathcal{B}$ denotes a branching fraction while $\sigma(B_c^+)$ and $\sigma(B^+)$ are the production cross-sections for $B_c^+$ and $B^+$ mesons. An indication of $\bar b c$ weak annihilation is found for the region $m(K^-\pi^+)<1.834\mathrm{\,Ge\kern -0.1em V\!/}c^2$, with a significance of 2.4 standard deviations.Comment: All figures and tables, along with any supplementary material and additional information, are available at https://lhcbproject.web.cern.ch/lhcbproject/Publications/LHCbProjectPublic/LHCb-PAPER-2016-022.html, link to supplemental material inserted in the reference

Measurement of the inclusive and dijet cross-sections of b-jets in pp collisions at sqrt(s) = 7 TeV with the ATLAS detector

The inclusive and dijet production cross-sections have been measured for jets containing b-hadrons (b-jets) in proton-proton collisions at a centre-of-mass energy of sqrt(s) = 7 TeV, using the ATLAS detector at the LHC. The measurements use data corresponding to an integrated luminosity of 34 pb^-1. The b-jets are identified using either a lifetime-based method, where secondary decay vertices of b-hadrons in jets are reconstructed using information from the tracking detectors, or a muon-based method where the presence of a muon is used to identify semileptonic decays of b-hadrons inside jets. The inclusive b-jet cross-section is measured as a function of transverse momentum in the range 20 < pT < 400 GeV and rapidity in the range |y| < 2.1. The bbbar-dijet cross-section is measured as a function of the dijet invariant mass in the range 110 < m_jj < 760 GeV, the azimuthal angle difference between the two jets and the angular variable chi in two dijet mass regions. The results are compared with next-to-leading-order QCD predictions. Good agreement is observed between the measured cross-sections and the predictions obtained using POWHEG + Pythia. MC@NLO + Herwig shows good agreement with the measured bbbar-dijet cross-section. However, it does not reproduce the measured inclusive cross-section well, particularly for central b-jets with large transverse momenta.Comment: 10 pages plus author list (21 pages total), 8 figures, 1 table, final version published in European Physical Journal

Kalimat Penegasan Pada Teks Terjemahan Al Quran Surat Al Ahzab

Teks terjemahan Al Quran tidak lepas dari paragraf atau kalimat di dalamnya. Sebuah judul juga harus baik dan kreatif agar mampu menarik minat pembaca untuk membaca informasinya secara lebih lanjut, inilah yang menarik untuk diteliti dan dikembangkan dalam kajian linguistik. Tujuan penelitian ini yaitu (1) Mendeskripsikan penanda kalimat penegasan pada teks terjemahan Al Quran surat Al Ahzab. (2) Memaparkan topik-topik yang ditegaskan pada teks terjemahan Al Quran surat Al Ahzab. (3) Memaparkan hubungan antarayat yang memiliki topik yang sama pada teks terjemahan Al Quran surat Al Ahzab. Objek dalam penelitian ini adalah kalimat penegasan pada teks terjemahan Al Quran surat Al Ahzab yaitu, penanda kalimat penegasan, topik-topik yang ditegaskan serta hubungan antar ayat yang memiliki topik yang sama. Penyediaan data dalam penelitian ini dilakukan dengan metode simak menggunakan teknik dasar yang berwujud teknik catat. Data dianalisis menggunakan metode padan intralingual dengan teknik dasar berupa teknik Pilah Unsur Penentu (PUP). Penyajian hasil analisis menggunakan metode penyajian informal. Hasil analisis penelitian ini terdapat (55 data). (1) penanda penegasan partikel : yang, lah- yang dan pun- lah, kontras makna, pemindahan unsur : predikat dan keterangan, bentuk pasif. (2) Topik yang ditegaskan Nabi dan rasulullah sebagai suri tauladan, orang kafir tidak akan selamat, Allah sebagai pemberi rahmat dan pelindung, Orang yang bersekutu atau orang munafik yang berhianat, orang mukmin atau orang beriman yang membela dan menjaga takwanya kepada Allah, himbauan Allah kepada istri nabi, pentingnya berdzikir kepada Allah, kewajiban orang mukmin memelihara kehormatannya, karunia yang diberikan Allah kepada manusia, tata cara memilih istri, anjuran berjilbab bagi perempuan, hari bangkitnya manusia dan hari pembalasan, kehidupan kaum yasrib, kehendak dan takdir Allah tidak bisa diubah, tidak dapat menghindar dari kematian, izin memasuki rumah nabi, larangan menikahi perempuan yang sudah dicerai dan larangan berhias seperti wanita jahiliyah. (3) Hubungan antarayat yang topiknya sama bersifat sebab akibat, saling melengkapi, urutan, penambahan dan kontras makna

Kontribusi Peran Guru, Budaya Sekolah, dan Kepemimpinan Kepala Sekolah terhadap Kualitas Pembelajaran di SMA Negeri 2 Sragen

Ely Tri Hartanti, Q 100 160 075, "The Contribution of Teachers' Roles, School Culture, and Principal Leadership to Quality of Learning in SMA Negeri 2 Sragen." Master of Education Management, Muhammadiyah University of Surakarta. 2018. This study aims to: 1) know the amount of positive contribution and significant role of teachers to the quality of learning in SMAN 2 Sragen. 2) know the amount of positive and significant contribution of school culture to the quality of learning in SMAN 2 Sragen. 3) know the amount of positive and significant contribution of headmaster leadership to the quality of learning in SMAN 2 Sragen. 4) know the magnitude of positive contribution and significant role of teachers, school culture, and leadership of the principal to the quality of learning of SMAN 2 Sragen. This research is a quantitative research with explanative technique. The population is Public Senior High School 2 Sragen students as many as 973 students with a sample of 100 respondents and the sampling technique uses proportional stratified random.. Data collection techniques used questionnaires to collect data on teacher role variables, school culture, principal leadership, and learning quality. Data analysis techniques used simultaneous statistical analysis with F test and partially using t test. The results showed: 1) there is a positive and significant contribution of teacher to the quality of learning in Public Senior High School 2 Sragen by 22.65%, 2) there is a positive and significant contribution of school culture to the quality of learning in Public Senior High School 2 Sragen by 23.31%, 3) there is a positive and significant contribution of headmaster leadership to the quality of learning in Public Senior High School 2 Sragen by 20.66%, 4) there is a positive and significant contribution of teacher role, school culture, and principal leadership to the quality of learning in Public Senior High School 2 Sragen 23.8%. Keywords: teacher role, school culture, principal leadership, quality of learnin

Observation of Bc+ →j /ψD (∗)K (∗) decays

A search for the decays B+c→J/ψD(*)0K+ and B+c→J/ψD(*)+K*0 is performed with data collected at the LHCb experiment corresponding to an integrated luminosity of 3 fb−1. The decays B+c→J/ψ0K+ and B+c→J/ψD*0K+ are observed for the first time, while first evidence is reported for the B+c→JψD*+K*0 and B+c→J/ψD+K*0 decays. The branching fractions of these decays are determined relative to the B+c→J/ψπ+ decay. The B+c mass is measured, using the J/ψD0K+ final state, to be 6274.28±1.40(stat)±0.32(syst) MeV/c2. This is the most precise single measurement of the B+c mass to date

Joy leads to overconfidence, and a simple countermeasure

Overconfidence has been identified as a source of suboptimal decision making in many real-life domains, with often far-reaching consequences. This study identifies a mechanism that can cause overconfidence and demonstrates a simple, effective countermeasure in an incentive-compatible experimental study. We observed that joy induced overconfidence if the reason for joy (an unexpected gift) was u

Komunikasi Keluarga Dalam Proses Pendampingan Pengobatan Anak Penderita Kanker (Studi Deskriptif Kualitatif Komunikasi Keluarga dalam Proses Pendampingan Pengobatan Anak Penderita Kanker di Yayasan Kasih Anak Kanker Indonesia (YKAKI) Jakarta)

ABSTRAK Penelitian ini tentang bagaimana komunikasi yang dilakukan ibu kepada anak selama proses pendampingan pengobatan di Rumah Singgah YKAKI, penelitian ini juga bertujuan untuk mendeskripsikan bagaimana komunikasi yang terjalin antara ibu dan anak selama proses pendampingan pengobatan di Rumah Singgah YKAKI. Metode yang digunakan dalam penelitian ini adalah metode penelitian kualitatif dengan menggunakan Teori Self Disclosure, Relation Maintenance, dan Interaksi Simbolik. Hasil penelitian ini menunjukkan bahwa komunikasi yang terjadi antara ibu dan anak selama proses pendampingan pengobatan di Rumah Singgah ibu tidak sepenuhnya terbuka kepada anak, ibu menutupi tekanan emosi dan kesedihannya pada anak sedangkan anak selalu terbuka terhadap ibunya. Selama proses pendampingan ibu senantiasa sabar dalam merawat anak dan selalu memotivasinya. Untuk memelihara hubungan keluarga agar terhindar dari konflik, ibu menggunakan strategi positif, keterbukaan, kepastian, jaringan sosial, dan juga pembagian tugas. Selama proses pendampingan pengobatan terjadi pertukaran simbol yang memiliki makna bahwa ibu selalu memotivasi anak melalui pesan verbal ataupun nonverbal. Pola komunikasi keluarga yang terjadi selama proses pendampingan pengobatan yaitu pola komunikasi persamaan yang berjalan dengan jujur, terbuka, langsung, dan bebas dari pemisahan kekuasaan. Kata Kunci: Komunikasi, Orang Tua, Penderita Kanker, Ana

Understanding missed opportunities for more timely diagnosis of cancer in symptomatic patients after presentation.

The diagnosis of cancer is a complex, multi-step process. In this paper, we highlight factors involved in missed opportunities to diagnose cancer more promptly in symptomatic patients and discuss responsible mechanisms and potential strategies to shorten intervals from presentation to diagnosis. Missed opportunities are instances in which post-hoc judgement indicates that alternative decisions or actions could have led to more timely diagnosis. They can occur in any of the three phases of the diagnostic process (initial diagnostic assessment; diagnostic test performance and interpretation; and diagnostic follow-up and coordination) and can involve patient, doctor/care team, and health-care system factors, often in combination. In this perspective article, we consider epidemiological 'signals' suggestive of missed opportunities and draw on evidence from retrospective case reviews of cancer patient cohorts to summarise factors that contribute to missed opportunities. Multi-disciplinary research targeting such factors is important to shorten diagnostic intervals post presentation. Insights from the fields of organisational and cognitive psychology, human factors science and informatics can be extremely valuable in this emerging research agenda. We provide a conceptual foundation for the development of future interventions to minimise the occurrence of missed opportunities in cancer diagnosis, enriching current approaches that chiefly focus on clinical decision support or on widening access to investigations.We acknowledge the helpful and incisive comments by Dr Rikke Sand Andersen (Aarhus University, Denmark) in conceptualising this piece and in drafts of the manuscript. The work is independent research supported by different funding schemes. GL was supported by a Post-Doctoral Fellowship by the National Institute for Health Research (PDF-2011-04-047) until the end of 2014 and by a Cancer Research UK Clinician Scientist Fellowship award (A18180) from 2015. HS is supported by the VA Health Services Research and Development Service (CRE 12-033; Presidential Early Career Award for Scientists and Engineers USA 14-274), the VA National Center for Patient Safety, the Agency for Health Care Research and Quality (R01HS022087) and in part by the Houston VA HSR&D Center for Innovations in Quality, Effectiveness and Safety (CIN 13–413). PV was supported by CaP, funded by The Danish Cancer Society and the Novo Nordisk Foundation.This is the final version of the article. It first appeared at http://dx.doi.org/10.1038/bjc.2015.4

Functional Social Support Moderates Stress on Depression in Individuals with CID during the COVID-19 Pandemic: A Two-Wave Study.

Depression is a common psychological experience for those living with a chronic illness and disease (CID). Social support (SS) can influence psychological health by regulating emotional functioning. The functional domain of SS refers to supportive exchange, including the emotional and instrumental functions. Public health measures during the COVID-19 pandemic include social distancing and isolation, which have impacted functional aspects of SS. The health risks of being isolated are comparable to the risks linked to obesity, blood pressure, and cigarette smoking. PURPOSE: To investigate the moderating effect of functional SS on the stress-depression relationship on individuals with CID during the COVID-19 pandemic. METHODS: Two waves of data were collected from a US sample: Apr. ’20: N = 321; Jun. ’20: N = 238. Participants completed the Patient Health Questionnaire–9 (depression symptoms), the Medical Outcomes Study–Social Support Survey–8 (perceived social support), and the Perceived Stress Scale–10 (perceived stress). For each wave of data, social support was entered as a moderator of the stress-depression relationship via multiple regression. RESULTS: The moderation models were estimated separately by wave. In the first wave, there was a negative but nonsignificant moderating effect (b = -0.19, p = .10) of social support on the stress-depression relationship (R2 = 51). In the second wave, the moderating relationship of social support doubled in magnitude (b = -0.30, p = .03, R2 = .57). During the COVID pandemic, functional social support weakened the association between stress and depression. CONCLUSION: Given the increased risk for social isolation and negative social exchange among people with CID during the COVID-19 pandemic, practitioners in rehabilitation psychology need to be informed about the potential implications of a lack of SS for the psychological health of the CID clients they work with. Drawing from the stress-buffering model and Lazarus et al.’s stress and coping theory (Lazarus, 1966; Lazarus & Folkman, 1984), our findings indicate that increased levels of perceived support can reduce the effects of stress on depression during the pandemic by contributing to fewer negative appraisals. Interventions targeting the particular functions of emotional (e.g., opportunities for emotional expression and venting) and instrumental (e.g., material aid) support could have immediate implications for facilitating rehabilitation outcomes (e.g., quality of life, interpersonal functioning, psychiatric symptomatology) during this public health crisis

An investigation into aripiprazole's partial D(2) agonist effects within the dorsolateral prefrontal cortex during working memory in healthy volunteers

Rationale: Working memory impairments in schizophrenia have been attributed to dysfunction of the dorsolateral prefrontal cortex (DLPFC) which in turn may be due to low DLPFC dopamine innervation. Conventional antipsychotic drugs block DLPFC D2 receptors, and this may lead to further dysfunction and working memory impairments. Aripiprazole is a D2 receptor partial agonist hypothesised to enhance PFC dopamine functioning, possibly improving working memory. Objectives: We probed the implications of the partial D2 receptor agonist actions of aripiprazole within the DLPFC during working memory. Investigations were carried out in healthy volunteers to eliminate confounds of illness or medication status. Aripiprazole’s prefrontal actions were compared with the D2/5-HT2A blocker risperidone to separate aripiprazole’s unique prefrontal D2 agonist actions from its serotinergic and striatal D2 actions that it shares with risperidone. Method: A double-blind, placebo-controlled, parallel design was implemented. Participants received a single dose of either 5 mg aripiprazole, 1 mg risperidone or placebo before performing the n-back task whilst undergoing fMRI scanning. Results: Compared with placebo, the aripiprazole group demonstrated enhanced DLPFC activation associated with a trend for improved discriminability (d’) and speeded reaction times. In contrast to aripiprazole’s neural effects, the risperidone group demonstrated a trend for reduced DLPFC recruitment. Unexpectedly, the risperidone group demonstrated similar effects to aripiprazole on d’ and additionally had reduced errors of commission compared with placebo. Conclusion: Aripiprazole has unique DLPFC actions attributed to its prefrontal D2 agonist action. Risperidone’s serotinergic action that results in prefrontal dopamine release may have protected against any impairing effects of its prefrontal D2 blockade