Percolation of hard disks

Random arrangements of points in the plane, interacting only through a simple hard core exclusion, are considered. An intensity parameter controls the average density of arrangements, in analogy with the Poisson point process. It is proved that at high intensity, an infinite connected cluster of excluded volume appears with positive probability.Comment: 16 pages, 6 figure

The moment index of minima (II)

The moment index of a nonnegative random variable X has the property that the moment index of the minimum of two independent r.v.s X and Y is greater than or equal to the sum of the moment indices of X and Y. We characterize conditions under which equality holds for a given r.v. X and every independent nonnegative r.v. Y, and discuss extensions to related r.v.s and their distributions

Dynamics of Rumor Spreading in Complex Networks

We derive the mean-field equations characterizing the dynamics of a rumor process that takes place on top of complex heterogeneous networks. These equations are solved numerically by means of a stochastic approach. First, we present analytical and Monte Carlo calculations for homogeneous networks and compare the results with those obtained by the numerical method. Then, we study the spreading process in detail for random scale-free networks. The time profiles for several quantities are numerically computed, which allow us to distinguish among different variants of rumor spreading algorithms. Our conclusions are directed to possible applications in replicated database maintenance, peer to peer communication networks and social spreading phenomena.Comment: Final version to appear in PR

Directionally Convex Ordering of Random Measures, Shot Noise Fields and Some Applications to Wireless Communications

Directionally convex ($dcx$) ordering is a tool for comparison of dependence structure of random vectors that also takes into account the variability of the marginal distributions. When extended to random fields it concerns comparison of all finite dimensional distributions. Viewing locally finite measures as non-negative fields of measure-values indexed by the bounded Borel subsets of the space, in this paper we formulate and study the $dcx$ ordering of random measures on locally compact spaces. We show that the $dcx$ order is preserved under some of the natural operations considered on random measures and point processes, such as deterministic displacement of points, independent superposition and thinning as well as independent, identically distributed marking. Further operations such as position dependent marking and displacement of points though do not preserve the $dcx$ order on all point processes, are shown to preserve the order on Cox point processes. We also examine the impact of $dcx$ order on the second moment properties, in particular on clustering and on Palm distributions. Comparisons of Ripley's functions, pair correlation functions as well as examples seem to indicate that point processes higher in $dcx$ order cluster more. As the main result, we show that non-negative integral shot-noise fields with respect to $dcx$ ordered random measures inherit this ordering from the measures. Numerous applications of this result are shown, in particular to comparison of various Cox processes and some performance measures of wireless networks, in both of which shot-noise fields appear as key ingredients. We also mention a few pertinent open questions.Comment: Accepted in Advances in Applied Probability. Propn. 3.2 strengthened and as a consequence Cor 6.1,6.2,6.

On a method to calculate conductance by means of the Wigner function: two critical tests

We have implemented the linear response approximation of a method proposed to compute the electron transport through correlated molecules based on the time-independent Wigner function [P. Delaney and J. C. Greer, \prl {\bf 93}, 36805 (2004)]. The results thus obtained for the zero-bias conductance through quantum dot both without and with correlations demonstrate that this method is either quantitatively nor qualitatively able to provide a correct physical escription of the electric transport through nanosystems. We present an analysis indicating that the failure is due to the manner of imposing the boundary conditions, and that it cannot be simply remedied.Comment: 22 pages, 7 figur

Spreading of Persistent Infections in Heterogeneous Populations

Up to now, the effects of having heterogeneous networks of contacts have been studied mostly for diseases which are not persistent in time, i.e., for diseases where the infectious period can be considered very small compared to the lifetime of an individual. Moreover, all these previous results have been obtained for closed populations, where the number of individuals does not change during the whole duration of the epidemics. Here, we go one step further and analyze, both analytically and numerically, a radically different kind of diseases: those that are persistent and can last for an individual's lifetime. To be more specific, we particularize to the case of Tuberculosis' (TB) infection dynamics, where the infection remains latent for a period of time before showing up and spreading to other individuals. We introduce an epidemiological model for TB-like persistent infections taking into account the heterogeneity inherent to the population structure. This sort of dynamics introduces new analytical and numerical challenges that we are able to sort out. Our results show that also for persistent diseases the epidemic threshold depends on the ratio of the first two moments of the degree distribution so that it goes to zero in a class of scale-free networks when the system approaches the thermodynamic limit.Comment: 12 pages and 2 figures. Revtex format. Submitted for publication

Investigations into the Sarcomeric Protein and Ca2+-Regulation Abnormalities Underlying Hypertrophic Cardiomyopathy in Cats (Felix catus).

Hypertrophic cardiomyopathy (HCM) is the most common single gene inherited cardiomyopathy. In cats (Felix catus) HCM is even more prevalent and affects 16% of the outbred population and up to 26% in pedigree breeds such as Maine Coon and Ragdoll. Homozygous MYBPC3 mutations have been identified in these breeds but the mutations in other cats are unknown. At the clinical and physiological level feline HCM is closely analogous to human HCM but little is known about the primary causative mechanism. Most identified HCM causing mutations are in the genes coding for proteins of the sarcomere. We therefore investigated contractile and regulatory proteins in left ventricular tissue from 25 cats, 18 diagnosed with HCM, including a Ragdoll cat with a homozygous MYBPC3 R820W, and 7 non-HCM cats in comparison with human HCM (from septal myectomy) and donor heart tissue. Myofibrillar protein expression was normal except that we observed 20–44% MyBP-C haploinsufficiency in 5 of the HCM cats. Troponin extracted from 8 HCM and 5 non-HCM cat hearts was incorporated into thin filaments and studied by in vitro motility assay. All HCM cat hearts had a higher (2.06 ± 0.13 fold) Ca2+-sensitivity than non-HCM cats and, in all the HCM cats, Ca2+-sensitivity was not modulated by troponin I phosphorylation. We were able to restore modulation of Ca2+-sensitivity by replacing troponin T with wild-type protein or by adding 100 μM Epigallocatechin 3-gallate (EGCG). These fundamental regulatory characteristics closely mimic those seen in human HCM indicating a common molecular mechanism that is independent of the causative mutation. Thus, the HCM cat is a potentially useful large animal model