Articulating Problems and Markets: A Translation Analysis of Entrepreneurs’ Emergent Value Propositions

In this qualitative study, the authors apply Callon’s sociology of translation to examine how new technology entrepreneurs enact material arguments that involve the first two moments of translation—problematization (defining a market problem) and interessement (defining a market and the firm’s relationship to it) - which in turn are represented in a claim, the value proposition. That emergent claim can then be represented and further changed during pitches. If accepted, it can then lead to the second two moments of translation: enrollment and mobilization. Drawing on written materials, observations, and interviews, we trace how these value propositions were iterated along three paths to better problematize and interesse, articulating a problem and market on which a business could plausibly be built. We conclude by discussing implications for understanding value propositions in entrepreneurship and, more broadly, using the sociology of translation to analyze emergent, material, consequential arguments. The study is based on data collected at the Austin Technology Incubator’s Student Entrepreneur Acceleration and Launch program (ATI SEAL) at The University of Texas at Austin.IC2 Institut

Axiomatic Deisgn of Manufacturing Systems

This paper introduces the use of axiomatic design in the design of manufacturing systems. The two primary functional requirements of any manufacturing system are developed. These functional requirements are then used to analyze the design of four manufacturing systems in terms of system performance.The purpose of this work is to provide a new foundation for describing, determining, and rationalizing the design of any new manufacturing system.Lean Aerospace Initiativ

Kepler-18b,c, and d: A System of Three Planets Confirmed by Transit Timing Variations, Light Curve Validation, Warm-Spitzer Photometry, and Radial Velocity Measurements

We report the detection of three transiting planets around a Sun-like star, which we designate Kepler-18. The transit signals were detected in photometric data from the Kepler satellite, and were confirmed to arise from planets using a combination of large transit-timing variations (TTVs), radial velocity variations, Warm-Spitzer observations, and statistical analysis of false-positive probabilities. The Kepler-18 star has a mass of 0.97 M_☉, a radius of 1.1 R_☉, an effective temperature of 5345 K, and an iron abundance of [Fe/H] = +0.19. The planets have orbital periods of approximately 3.5, 7.6, and 14.9 days. The innermost planet "b" is a "super-Earth" with a mass of 6.9 ± 3.4 M_⊕, a radius of 2.00 ± 0.10 R_⊕, and a mean density of 4.9 ± 2.4 g cm^3. The two outer planets "c" and "d" are both low-density Neptune-mass planets. Kepler-18c has a mass of 17.3 ± 1.9 M_⊕, a radius of 5.49 ± 0.26 R_⊕, and a mean density of 0.59 ± 0.07 g cm^3, while Kepler-18d has a mass of 16.4 ± 1.4 M_⊕, a radius of 6.98 ± 0.33 R_⊕ and a mean density of 0.27 ± 0.03 g cm^3. Kepler-18c and Kepler-18d have orbital periods near a 2:1 mean-motion resonance, leading to large and readily detected TTVs

Understanding Lean Manufacturing According to Axiomatic Design Principles

In this paper, a sequence of implementation steps will be developed through the application of axiomatic design. This sequence will provide a design methodology for lean production which connects manufacturing system design objectives to operation design parameters.Lean Aerospace Initiativ

Axiomatic Design of Manufacturing Systems

This paper introduces the use of axiomatic design in the design of manufacturing systems. The two primary functional requirements of any manufacturing system are developed. These functional requirements are used to analyze the design of four manufacturing systems in terms of system performance. The purpose of this work is to provide a new foundation for describing, determining and rationalizing the design of any new manufacturing system

The Fabrication and Integration of a 15 MHz Array Within a Biopsy Needle

It is proposed that integrating ultrasound transducer arrays at the tip of tools such as biopsy needles could enable valuable, real-time image feedback during interventional procedures. High-resolution ultrasound imaging has the potential to aid navigation of interventional tools, and to assist diagnosis or treatment via in-vivo tissue characterisation in the breast, amongst many other applications. In order to produce miniature transducer arrays incorporated within biopsy needle-sized packages (2-5 mm diameter), the challenges in micromachining and handling transducer materials at this scale must be overcome. This paper presents fabrication processes used in the micromachining of a 16 element 15 MHz PIN-PMN-PT piezocrystal-polymer composite array and its integration into an 11 G breast biopsy needle. Particular emphasis is given to the manufacturing of the 1-3 dice-and-fill piezocrystal composite, and establishing electrical interconnects. Characterisation measurements have demonstrated operation of each of the 16 elements within the needle case

Possible Observational Criteria for Distinguishing Brown Dwarfs from Planets

The difference in formation process between binary stars and planetary systems is reflected in their composition as well as their orbital architecture, particularly orbital eccentricity as a function of orbital period. It is suggested here that this difference can be used as an observational criterion to distinguish between brown dwarfs and planets. Application of the orbital criterion suggests that with three possible exceptions, all of the recently-discovered substellar companions discovered to date may be brown dwarfs and not planets. These criterion may be used as a guide for interpretation of the nature of sub-stellar mass companions to stars in the future.Comment: LaTeX, 11 pages including 2 figures, accepted for publication in the Astrophysical Journal Letter

Light sheet microscopy with acoustic sample confinement

Contactless sample confinement would enable a whole host of new studies in developmental biology and neuroscience, in particular, when combined with long-term, wide-field optical imaging. To achieve this goal, we demonstrate a contactless acoustic gradient force trap for sample confinement in light sheet microscopy. Our approach allows the integration of real-time environmentally controlled experiments with wide-field low photo-toxic imaging, which we demonstrate on a variety of marine animal embryos and larvae. To illustrate the key advantages of our approach, we provide quantitative data for the dynamic response of the heartbeat of zebrafish larvae to verapamil and norepinephrine, which are known to affect cardiovascular function. Optical flow analysis allows us to explore the cardiac cycle of the zebrafish and determine the changes in contractile volume within the heart. Overcoming the restrictions of sample immobilisation and mounting can open up a broad range of studies, with real-time drug-based assays and biomechanical analyses.</p

The Kepler Follow-up Observation Program

The Kepler Mission was launched on March 6, 2009 to perform a photometric survey of more than 100,000 dwarf stars to search for terrestrial-size planets with the transit technique. Follow-up observations of planetary candidates identified by detection of transit-like events are needed both for identification of astrophysical phenomena that mimic planetary transits and for characterization of the true planets and planetary systems found by Kepler. We have developed techniques and protocols for detection of false planetary transits and are currently conducting observations on 177 Kepler targets that have been selected for follow-up. A preliminary estimate indicates that between 24% and 62% of planetary candidates selected for follow-up will turn out to be true planets.Comment: 12 pages, submitted to the Astrophysical Journal Letter