Supporting Women Entrepreneurs in Ireland

Entrepreneurship development is an important requirement for achieving the goal of smart, sustainable and inclusive growth set out in the Europe 2020 strategy. It is also a means to respond to new economic challenges, to create jobs and to fight social and financial exclusion. The impact of the global financial and economic crisis calls for giving entrepreneurship and self-employment a stronger role in economic and social development policies. Inclusive entrepreneurship policies and programmes are particularly relevant for women who continue to face challenges in the labour market and are under-represented in entrepreneurship activities. However, the effectiveness of national, regional and local measures and actions to promote inclusive entrepreneurship development in Europe can be hindered by a fragmentation of responsibilities, resources and strategies, and a failure to understand the goals of inclusive entrepreneurship

Universities, Entrepreneurship and Local Development

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Excitatory Input Onto Hilar Somatostatin Interneurons Is Increased in a Chronic Model of Epilepsy

The density of somatostatin (SOM)-containing GABAergic interneurons in the hilus of the dentate gyrus is significantly decreased in both human and experimental temporal lobe epilepsy. We used the pilocarpine model of status epilepticus and temporal lobe epilepsy in mice to study anatomical and electrophysiological properties of surviving somatostatin interneurons and determine whether compensatory functional changes occur that might offset loss of other inhibitory neurons. Using standard patch-clamp techniques and pipettes containing biocytin, whole cell recordings were obtained in hippocampal slices maintained in vitro. Hilar SOM cells containing enhanced green fluorescent protein (EGFP) were identified with fluorescent and infrared differential interference contrast video microscopy in epileptic and control GIN (E GFP-expressing Inhibitory Neurons) mice. Results showed that SOM cells from epileptic mice had 1) significant increases in somatic area and dendritic length; 2) changes in membrane properties, including a small but significant decrease in resting membrane potential, and increases in time constant and whole cell capacitance; 3) increased frequency of slowly rising spontaneous excitatory postsynaptic currents (sEPSCs) due primarily to increased mEPSC frequency, without changes in the probability of release; 4) increased evoked EPSC amplitude; and 5) increased spontaneous action potential generation in cell-attached recordings. Results suggest an increase in excitatory innervation, perhaps on distal dendrites, considering the slower rising EPSCs and increased output of hilar SOM cells in this model of epilepsy. In sum, these changes would be expected to increase the inhibitory output of surviving SOM interneurons and in part compensate for interneuronal loss in the epileptogenic hippocampus. </jats:p

Entrepreneurial opportunities and working conditions of self-employed online freelancers in the platform economy: Lessons from the COVID-19 pandemic

This paper examines the experiences of self-employed online freelancers working on digital labour platforms during the COVID-19 pandemic. It is based on interviews with freelancers and platform managers and experts in Belgium, France, Italy, the Netherlands and Poland. Their experiences during COVID-19 reveal issues of asymmetric power vis-à-vis platforms. Notably, they reported lack of transparency and certainty in their contracts with platforms, lack of power in negotiating with clients, and limited ability to engage with clients on other platforms. In addition, they often experienced difficulties in accessing government temporary supports for businesses during the pandemic. The paper puts forward policy recommendations to address these issues

Revealing the hidden carbon in forested wetland soils

Abstract Inland wetlands are critical carbon reservoirs storing 30% of global soil organic carbon (SOC) within 6% of the land surface. However, forested regions contain SOC-rich wetlands that are not included in current maps, which we refer to as ‘cryptic carbon’. Here, to demonstrate the magnitude and distribution of cryptic carbon, we measure and map SOC stocks as a function of a continuous, upland-to-wetland gradient across the Hoh River Watershed (HRW) in the Pacific Northwest of the U.S., comprising 68,145 ha. Total catchment SOC at 30 cm depth (5.0 TgC) is between estimates from global SOC maps (GSOC: 3.9 TgC; SoilGrids: 7.8 TgC). For wetland SOC, our 1 m stock estimates are substantially higher (Mean: 259 MgC ha−1; Total: 1.7 TgC) compared to current wetland-specific SOC maps derived from a combination of U.S. national datasets (Mean: 184 MgC ha−1; Total: 0.3 TgC). We show that total unmapped or cryptic carbon is 1.5 TgC and when added to current estimates, increases the estimated wetland SOC stock to 1.8 TgC or by 482%, which highlights the vast stores of SOC that are not mapped and contained in unprotected and vulnerable wetlands