Microstructural Characterization of TiO2-II in the Chicxulub Peak Ring

The peak ring of the approximately 180 kilometer-diameter Chicxulub impact crater on the Yucatan Peninsula, Mexico, was recently drilled during IODP-ICDP (International Ocean Discovery Program-International Continental Scientific Drilling Program) Expedition 364, producing core M0077A. The new core provides insights into the anatomy, composition, tectonic deformation, shock metamorphism, and post-impact overprint of crater-filling impactites and crystalline basement rocks. The basement rocks were shocked to approximately 12.5-17.5 gigapascals, uplifted, and hydrothermally altered. This study presents a combined Raman spectroscopic and electron backscatter diffraction (EBSD) study of TiO2-II, a high-pressure polymorph of TiO2 with an alpha-PbO2 structure (orthorhombic; space group Pbcn; density 4.34 grams per cubic centimeter, in shocked granitoid rock of the Chicxulub peak ring

Patterns of psychotropic prescribing and polypharmacy in older hospitalized patients in Ireland: the influence of dementia on prescribing

Neuropsychiatric Symptoms (NPS) are ubiquitous in dementia and are often treated pharmacologically. The objectives of this study were to describe the use of psychotropic, anti-cholinergic, and deliriogenic medications and to identify the prevalence of polypharmacy and psychotropic polypharmacy, among older hospitalized patients in Ireland, with and without dementia. All older patients (≥ 70 years old) that had elective or emergency admissions to six Irish study hospitals were eligible for inclusion in a longitudinal observational study. Of 676 eligible patients, 598 patients were recruited and diagnosed as having dementia, or not, by medical experts. These 598 patients were assessed for delirium, medication use, co-morbidity, functional ability, and nutritional status. We conducted a retrospective cross-sectional analysis of medication data on admission for 583/598 patients with complete medication data, and controlled for age, sex, and co-morbidity. Of 149 patients diagnosed with dementia, only 53 had a previous diagnosis. At hospital admission, 458/583 patients experienced polypharmacy (≥ 5 medications). People with dementia (PwD) were significantly more likely to be prescribed at least one psychotropic medication than patients without dementia (99/147 vs. 182/436; p < 0.001). PwD were also more likely to experience psychotropic polypharmacy (≥ two psychotropics) than those without dementia (54/147 vs. 61/436; p < 0.001). There were no significant differences in the prescribing patterns of anti-cholinergics (23/147 vs. 42/436; p = 0.18) or deliriogenics (79/147 vs. 235/436; p = 0.62). Polypharmacy and psychotropic drug use is highly prevalent in older Irish hospitalized patients, especially in PwD. Hospital admission presents an ideal time for medication reviews in PwD

Palliative care and Parkinson's disease : meeting summary and recommendations for clinical research

Introduction: Palliative care is an approach to caring for patients and families affected by serious illnesses that focuses on the relief of suffering through the management of medical symptoms, psychosocial issues, advance care planning and spiritual wellbeing. Over the past decade there has been an emerging clinical and research interest in the application of palliative care approaches to Parkinson’s disease (PD) and outpatient palliative care services are now offered by several movement disorders centers. Methods: An International Working Group Meeting on PD and Palliative Care supported by the Parkinson’s Disease Foundation was held in October 2015 to review the current state of the evidence and to make recommendations for clinical research and practice. Results: Topics included: 1) Defining palliative care for PD; 2) Lessons from palliative care for heart failure and other chronic illnesses; 3) Patient and caregiver Needs; 4) Needs assessment tools; 5) Intervention strategies; 6) Predicting prognosis and hospice referrals; 7) Choice of appropriate outcome measures; 8) Implementation, dissemination and education research; and 9) Need for research collaborations. We provide an overview of these discussions, summarize current evidence and practices, highlight gaps in our knowledge and make recommendations for future research. Conclusions: Palliative Care for PD is a rapidly growing area which holds great promise for improving outcomes for PD patients and their caregivers. While clinical research in this area can build from lessons learned in other diseases, there is a need for observational, methodological and interventional research to address the unique needs of PD patients and caregivers

Local Foods: Estimating Capacity

While local food is enjoying new interest in much of the country, data revealing the extent of local food production and consumption are typically lacking. This lack of data has made it difficult to set local food goals and assess progress toward such goals. This article describes two methods for quantifying local food consumption and presents estimation results using national and state data. The local food indicators presented in this article can be easily estimated with publicly available data and represent low cost indicators of local food use that Extension professionals can use to assist clientele

Institute Brief: Achieving Quality Services: A Checklist for Evaluating Your Agency

This checklist can help staff and directors at One-Stop Career Centers and state and private agencies evaluate the quality and responsiveness of their services to job seekers with disabilities. Areas covered include access to resources, agency culture, coordination, and consumer-directedness

Tools for Inclusion: Evaluating Your Agency and Its Services: A Checklist for Job Seekers with Disabilities

It is important to evaluate employment services and decide if you are getting the results that you are looking for. You should have high expectations! If you are currently using an agency for help with employment, this checklist can help you make sure you are getting what you need

A cross‐sectional study of academic success measures, grit, and resilience among US dental students

Purpose: This study explored themes previously identified as central to holistic professional school success, as related to traditional academic achievement, resilience, and grit measures. Methods: This cross‐sectional study surveyed third‐ and fourth‐year US dental students. Items addressed themes previously identified as central to professional school success, including need for cognition, patient ownership, collective orientation, grit, and resilience. Traditional academic metrics were also included. Statistical analyses comprised one‐way analysis of variance (ANOVA), simple linear regression, and stepwise multiple regression procedures. Results: A total of 126 students participated (81% response rate). Collective orientation, need for cognition, patient ownership, and resilience did not significantly correlate with grade point average (GPA), whereas grit did, r = 0.29. Need for cognition and patient ownership combined significantly predicted grit with approximately 35% of variance explained. Approximately 25% of variance in resilience scores was accounted for by need for cognition, coupled with collective orientation. Grit and resilience significantly correlated, r = 0.59. Conclusions: Grit significantly predicted both traditional and alternative metrics of success among dental students, particularly need for cognition and patient ownership. A high need for cognition is consistent among students who display both grit and resilience. Neither resilience nor the alternative measures of success predicted traditional academic metrics