Development of a coded 16-ary CPFSK coherent demodulator

Theory and hardware are described for a proof-of-concept 16-ary continuous phase frequency shift keying (16-CPFSK) digital modem. The 16 frequencies are spaced every 1/16th baud rate for 2 bits/sec/Hz operation. Overall rate 3/4 convolutional coding is incorporated. The demodulator differs significantly from typical quadrature phase detector approaches in that phase is coherently measured by processing the baseband output of a frequency discriminator. Baud rate phase samples from the baseband processor are decoded to yield the original data stream. The method of encoding onto the 16-ary phase nodes, together with convolutional coding gain, results in near quad PSK (QPSK) performance. The modulated signal is of constant envelope; thus the power amplifier can be saturated for peak performance. The spectrum is inherently bandlimited and requires no RF filter

A production modeling approach to the assessment of the horseshoe crab (Limulus polyphemus) population in Delaware Bay

Horseshoe crab (Limulus polyphemus) is harvested commercially, used by the biomedical industry, and provides food for migrating shorebirds, particularly in Delaware Bay. Recently, decreasing crab population trends in this region have raised concerns that the stock may be insufficient to fulfill the needs of these diverse user groups. To assess the Delaware Bay horseshoe crab population, we used surplus production models (programmed in ASPIC), which incorporated data from fishery-independent surveys, fishery-dependent catch-per-unit-of-effort data, and regional harvest. Results showed a depleted population (B2003/=0.03−0.71) BMSY and high relative fishing mortality /FMSY=0.9−9.5). Future harvest (F2002strategies for a 15-year period were evaluated by using population projections with ASPICP software. Under 2003 harvest levels (1356 t), population recovery to BMSY would take at least four years, and four of the seven models predicted that the population would not reach BMSY within the 15year period. Production models for horseshoe crab assessment provided management benchmarks for a species with limited data and no prior stock assessmen

Results of A Local Combination Therapy Antibiogram For \u3cem\u3ePseudomonas Aeruginosa\u3c/em\u3e Isolates: Is Double Worth The Trouble?

Purpose: To determine the frequency at which fluoroquinolones and aminoglycosides demonstrate in vitro activity against non-urinary, non-skin/skin structure Pseudomonas aeruginosa isolates exhibiting decreased susceptibilities to one or more β-lactam agents. Methods: β-lactam-non-susceptible P. aeruginosa isolates recovered from blood, bone, lower respiratory tract, pleural fluid, cerebrospinal fluid, or peritoneal fluid cultures between October 2010 and October 2014 were reviewed from four community hospitals within a single health-system. Only the first isolate per patient was included for analysis. The likelihood that each isolate was susceptible to a non-β-lactam antimicrobial was then determined and summarized within a combination antibiogram. Results: In total, 179 P. aeruginosa isolates with decreased susceptibilities to one or more β-lactam agents were assessed. Because no appreciable differences in antimicrobial susceptibility profile were observed between hospitals, the isolates were evaluated in aggregate. Susceptibility rates for β-lactam monotherapy ranged from 34% to 75%. Aminoglycosides possessed increased antibacterial activity compared to fluoroquinolones. Tobramycin was the non-β-lactam most likely to expand antimicrobial coverage against β-lactam-non-susceptible P. aeruginosa with activity against 64%, 66%, and 65% of cefepime-, piperacillin-tazobactam-, and meropenem-non-susceptible isolates, respectively (p \u3c 0.001 for all). Conclusions: The results of this study support the use of aminoglycosides over fluoroquinolones for achieving optimal, empiric antimicrobial combination therapy for P. aeruginosa when dual antimicrobial therapy is clinically necessary. Future efforts aimed at optimizing combination therapy for P. aeruginosa should focus on systemic interventions that limit the selection of fluoroquinolones in combination with β-lactams to expand coverage based on local susceptibility rates

Evaluation of the effectiveness of care groups in expanding population coverage of Key child survival interventions and reducing under-5 mortality: a comparative analysis using the lives saved tool (LiST)

BACKGROUND: Globally, less than half of Countdown Countries will achieve the Millennium Development Goal of reducing the under-5 mortality rate (U5MR) by two-thirds by 2015. There is growing interest in community-based delivery mechanisms to help accelerate progress. One promising approach is the use of a form of participatory mothers’ groups, called Care Groups, for expanding coverage of key child survival interventions, an essential feature for achieving mortality impact. METHODS: In this study we evaluate the effectiveness of Care Group projects conducted in 5 countries in Africa and Asia in comparison to other United States Agency for International Development-funded child survival projects in terms of increasing coverage of key child survival interventions and reducing U5MR (estimated using the Lives Saved Tool, or LiST). Ten Care Group and nine non-Care Group projects were matched by country and year of program implementation. RESULTS: In Care Group project areas, coverage increases were more than double those in non-Care Group project areas for key child survival interventions (p = 0.0007). The mean annual percent change in U5MR modelled in LiST for the Care Group and non-Care Group projects was −4.80 % and −3.14 %, respectively (p = 0.09). CONCLUSIONS: Our findings suggest that Care Groups may provide a promising approach to significantly increase key child survival interventions and increase reductions in U5MR. Evaluations of child survival programs should be a top priority in global health to build a greater evidence base for effective approaches for program delivery

Major improvements in progress for Southern California Earthquake Monitoring

Major improvements in seismic and strong-motion monitoring networks are being implemented in southern California to better meet the needs of emergency response personnel, structural engineers, and the research community in promoting earthquake hazard reduction. Known as the TriNet project, the improvements are being coordinated by the California Institute of Technology (Caltech), the U.S. Geological Survey (USGS), and the California Division of Mines and Geology (CDMG) of the state's Department of Conservation. Already the ambitious instrument and system development project has started to record and disseminate ground motions from a spatially dense and robust network of high quality seismographs

Distortion of the acoustic peaks in the CMBR due to a primordial magnetic field

In this paper we study the effect of a magnetic field on the fluctuation spectrum of the cosmic microwave background. We find that upcoming measurements might give interesting bounds on large scale magnetic fields in the early Universe. If the effects are seen, it might be possible to establish the presence of different fields in different patches of the sky. Absence of any effect, will provide by one order of magnitude a better limit for a primordial field, now given by nucleosynthesis.Comment: 10 pages, 2 .ps figures included, extra reference added and typographical errors correcte