27,798 research outputs found

    Effects of low energy proton, electron, and simultaneously combined proton and electron environments in silicon and GaAs solar cells

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    Degradation of silicon and GaAs solar cells due to exposures to low energy proton and electron environments and annealing data for these cells are discussed. Degradation of silicon cells in simultaneously combined electron and low energy proton environments and previous experimental work is summarized and evaluated. The deficiencies in current solar array damage prediction techniques indicated by these data and the relevance of these deficiencies to specific missions such as intermediate altitude orbits and orbital transfer vehicles using solar electric propulsion systems are considered

    Permutative categories, multicategories, and algebraic K-theory

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    We show that the KK-theory construction of arXiv:math/0403403, which preserves multiplicative structure, extends to a symmetric monoidal closed bicomplete source category, with the multiplicative structure still preserved. The source category of arXiv:math/0403403, whose objects are permutative categories, maps fully and faithfully to the new source category, whose objects are (based) multicategories

    Measurement of the SOC State Specific Heat in ^4He

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    When a heat flux Q is applied downward through a sample of liquid 4He near the lambda transition, the helium self organizes such that the gradient in temperature matches the gravity induced gradient in Tlambda. All the helium in the sample is then at the same reduced temperature tSOC = ((T[sub SOC] - T[sub lambda])/T[sub lambda]) and the helium is said to be in the Self-Organized Critical (SOC) state. We have made preliminary measurements of the 4He SOC state specific heat, C[del]T(T(Q)). Despite having a cell height of 2.54 cm, our results show no difference between C[del]T and the zero-gravity 4He specific heat results of the Lambda Point Experiment (LPE) [J.A. Lipa et al., Phys. Rev. B, 68, 174518 (2003)] over the range 250 to 450 nK below the transition. There is no gravity rounding because the entire sample is at the same reduced temperature tSOC(Q). Closer to Tlambda the SOC specific heat falls slightly below LPE, reaching a maximum at approximately 50 nK below Tlambda, in agreement with theoretical predictions [R. Haussmann, Phys. Rev. B, 60, 12349 (1999)]

    Detoxification in rehabilitation in England: effective continuity of care or unhappy bedfellows?

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    There is evidence that residential detoxification alone does not provide satisfactory treatment outcomes and that outcomes are significantly enhanced when clients completing residential detoxification attend rehabilitation services (Gossop, Marsden, Stewart, & Rolfe, 1999; Ghodse, Reynolds, Baldacchino, et al., 2002). One way of increasing the likelihood of this continuity of treatment is by providing detoxification and rehabilitation within the same treatment facility to prevent drop-out, while the client awaits a rehabilitation bed or in the transition process. However, there is little research evidence available on the facilities that offer both medical detoxification and residential rehabilitation. The current study compares self-reported treatment provision in 87 residential rehabilitation services in England, 34 of whom (39.1%) reported that they offered detoxification services within their treatment programmes. Although there were no differences in self-reported treatment philosophies, residential rehabilitation services that offered detoxification were typically of shorter duration overall, had significantly more beds and reported offering more group work than residential rehabilitation services that did not offer detoxification. Outcomes were also different, with twice as many clients discharged on disciplinary grounds from residential rehabilitation services without detoxification facilities. The paper questions the UK classification of residential drug treatment services as either detoxification or rehabilitation and suggests the need for greater research focus on the aims, processes and outcomes of this group of treatment providers

    Benchmark ultra-cool dwarfs in widely separated binary systems

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    Ultra-cool dwarfs as wide companions to subgiants, giants, white dwarfs and main sequence stars can be very good benchmark objects, for which we can infer physical properties with minimal reference to theoretical models, through association with the primary stars. We have searched for benchmark ultra-cool dwarfs in widely separated binary systems using SDSS, UKIDSS, and 2MASS. We then estimate spectral types using SDSS spectroscopy and multi-band colors, place constraints on distance, and perform proper motions calculations for all candidates which have sufficient epoch baseline coverage. Analysis of the proper motion and distance constraints show that eight of our ultra-cool dwarfs are members of widely separated binary systems. Another L3.5 dwarf, SDSS 0832, is shown to be a companion to the bright K3 giant Eta Cancri. Such primaries can provide age and metallicity constraints for any companion objects, yielding excellent benchmark objects. This is the first wide ultra-cool dwarf + giant binary system identified.Comment: 4 pages, 3 figures, conference, "New Technologies for Probing the Diversity of Brown Dwarfs and Exoplanets", oral tal

    Galcanezumab in episodic migraine: subgroup analyses of efficacy by high versus low frequency of migraine headaches in phase 3 studies (EVOLVE-1 & EVOLVE-2).

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    BACKGROUND: Patients with high-frequency episodic migraine (HFEM) have a greater disease burden than those with low-frequency episodic migraine (LFEM). Acute treatment overuse increases the risk of migraine chronification in patients with HFEM. Galcanezumab, a humanized monoclonal antibody binding calcitonin gene-related peptide (CGRP), is effective for migraine prevention with a favorable safety profile. Here, we investigate whether there are differences in galcanezumab efficacy in patients with LFEM or with HFEM. METHODS: Data were pooled from two double-blind, placebo-controlled phase 3 trials; EVOLVE-1 and EVOLVE-2. Patients were 18-65 years old, experienced 4-14 monthly migraine headache days (MHDs) for ≥1 year prior, with onset at \u3c 50 years of age. Migraine headaches were tracked via electronic patient-reported outcome system and randomization was stratified by low (LFEM; 4-7 monthly MHDs) or high (HFEM; 8-14 monthly MHDs) frequency. Subgroup analysis compared the HFEM and LFEM subgroups with a linear or generalized linear mixed model repeated measures approach. RESULTS: The intent-to-treat patients (N = 1773) had a mean age of 41.3 years, were mostly white (75%), female (85%), and 66% of patients had HFEM. In both the LFEM and HFEM subgroups, the overall (Months 1-6) and monthly changes from baseline in monthly MHDs and monthly MHDs with acute medication use compared with placebo were statistically significantly reduced for galcanezumab 120-mg and 240-mg. Galcanezumab (120-mg and 240-mg) significantly decreased the overall and monthly MHDs with nausea and/or vomiting, and with photophobia and phonophobia versus placebo in patients with LFEM or HFEM. In both subgroups, the mean overall (Months 1-6) and monthly percentages of patients with ≥50%, ≥75%, and 100% reduction in monthly MHDs from baseline were statistically significantly greater in patients receiving either dose of galcanezumab versus placebo. Galcanezumab (120-mg and 240-mg) significantly improved the Migraine-Specific Quality of Life Questionnaire role function-restrictive domain score as well as the Migraine Disability Assessment total score versus placebo for patients with LFEM or HFEM. There were no significant subgroup-by-treatment interactions. CONCLUSIONS: Galcanezumab was as effective in patients with HFEM as in those with LFEM. Associated symptoms, quality of life, and disability were similarly improved in patients with HFEM or LFEM. TRIAL REGISTRATION: NCT02614183 , NCT02614196

    Control System for the LEDA 6.7-MeV Proton Beam Halo Experiment

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    Measurement of high-power proton beam-halo formation is the ongoing scientific experiment for the Low Energy Demonstration Accelerator (LEDA) facility. To attain this measurement goal, a 52-magnet beam line containing several types of beam diagnostic instrumentation is being installed. The Experimental Physics and Industrial Control System (EPICS) and commercial software applications are presently being integrated to provide a real-time, synchronous data acquisition and control system. This system is comprised of magnet control, vacuum control, motor control, data acquisition, and data analysis. Unique requirements led to the development and integration of customized software and hardware. EPICS real-time databases, Interactive Data Language (IDL) programs, LabVIEW Virtual Instruments (VI), and State Notation Language (SNL) sequences are hosted on VXI, PC, and UNIX-based platforms which interact using the EPICS Channel Access (CA) communication protocol. Acquisition and control hardware technology ranges from DSP-based diagnostic instrumentation to the PLC-controlled vacuum system. This paper describes the control system hardware and software design, and implementation.Comment: LINAC2000 Conference, 4 pg

    Radioisotope thermal photovoltaic application of the GaSb solar cell

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    An examination of a RTVP (radioisotopic thermophotovoltaic) conceptual design has shown a high potential for power densities well above those achievable with radioisotopic thermoelectric generator (RTG) systems. An efficiency of 14.4 percent and system specific power of 9.25 watts/kg were predicted for a system with sixteen GPHS (general purpose heat source) sources operating at 1100 C. The models also showed a 500 watt system power by the strontium-90 isotope at 1200 C at an efficiency of 17.0 percent and a system specific power of 11.8 watts/kg. The key to this level of performance is a high-quality photovoltaic cell with narrow bandgap and a reflective rear contact. Recent work at Boeing on GaSb cells and transparent back GaAs cells indicate that such a cell is well within reach
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