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Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19: The REMAP-CAP COVID-19 Corticosteroid Domain Randomized Clinical Trial.
- Author
- Abbass Hakam
- Adhikari Neill
- Affleck Julia
- Agno Sathianathan Ronan
- Ahmad Norfaizan
- Ahmed Iram
- Ainscough Kate
- Al Qasim Eman
- Al Swaidan Lolowa
- Al-Bassam Wisam
- Al-Beidh Farah
- Al-Beidh Farah
- Albert Martin
- Alegria Ana
- Alexander Brian
- Alexander Peter
- Allan Angela
- Allan Elizabeth
- Allen Louise
- Allibone Suzanne
- Amaro dos Santos Catorze Teodoro
- Anderson Tom
- Andric Zdravko
- Angus Derek
- Angus Derek C
- Anjum Aisha
- Ankert Juliane
- Annane Djillali
- Annane Djillali
- Anstey Matthew
- Antcliffe David
- Aparicio Christelle
- Appelt Peter
- Arabi Yaseen
- Arabi Yaseen
- Arbane Gill
- Archer Simon
- Aref Noah
- Arias Ana-Marie
- Arishi Hatim
- Arnold Donald
- Asghar Adeeba
- Ashelford Angela
- Attwood Ben
- Austin Karen
- Aysel Florescu Simin
- Azaiz Amine
- Babel Jakša
- Babio-Galan Maite
- Badie Julio
- Bagshaw Sean
- Baillie Kenneth
- Baker Evelyn
- Bakthavatsalam Dhanalakshmi
- Bamford Peter
- Banach Dorota
- Bannard-Smith Jonathan
- Barbazza Leanne
- Barber Russell
- Barge Deborah
- Barnes Nicky
- Baršić Bruno
- Bashyal Archana
- Basile Kim
- Bass Frances
- Bates Michelle
- Bauchmuller Kris
- Bean Sarah
- Beane Abigail
- Beane Abigail
- Beasley Richard
- Begin Phillipe
- Bellemare David
- Benettaib Fatna
- Benzekri Dalila
- Berdaguer Fernando Daniel
- Bergin Colin
- Berry Lindsay
- Berry Lindsay
- Berry Scott
- Berry Scott
- Bhimani Zahra
- Bhimani Zahra
- Bihari Shailesh
- Bihari Shilesh
- Binnie Alexandra
- Bion Julian
- Biradar Vishwanath
- Birch Janine
- Birch Jenny
- Birchall Katie
- Birkinshaw Isobel
- Black Ethel
- Bloos Frank
- Board Jasmin
- Bone Allsion
- Bonner Stephen
- Bonten Marc
- Bonten Marc
- Borgatta Barbara
- Borrill Zoe
- Bosch Ziekenhuis Jeroen
- Boschert Catherine
- Bossard Isabelle
- Boumahni Dounia
- Bourgoin Charlotte
- Bourne Michelle
- Bourne Richard
- Bouwman Wietske
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- Boyd Craig
- Bracke Stephanie
- Bradbury Charlotte
- Bradbury Charlotte
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- Brailsford Jane
- Brain Matthew
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- Brickell Kathy
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- Brimfield Lutece
- Brinkerhoff Gail
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- Brohi Farooq
- Browne Troy
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- Brunkhorst Frank
- Budd Joanna
- Buehner Ulrike
- Buhr Heidi
- Bullman Laetitia
- Burns Karen
- Burt Karen
- Buscher Hergen
- Butler Amelia
- Butler M
- Buxton Meredith
- Buxton Meredith
- Buzgau Adrian
- Byrne Deborah
- Byrne Kathleen
- Bélteczki János
- Cabreros Leilani
- Calfee Carolyn
- Callender Owen
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- Chablani Manish
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- Charron Cyril
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- Chassé Michaël
- Chen Yan
- Cheng Allen
- Cheng Allen C
- Cherian Shiney
- Cheung Winston
- Chhablani Manish
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- de Jager P
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- Fysh Ed
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- Ganguly Saibal
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- Goodwin Jayne
- Goossens Herman
- Goossens Herman
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- Gordon Anthony C
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- Gosbell Iain
- Gould Richard
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- Green Cameron
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- Guilder E
- Guitton Christophe
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- Hagel Stefan
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- Haniffa Rashan
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- Hickey Naomi
- Higgins Alisa M
- Higgins Lisa
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- Hullegie Sebastiaan J
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- Seymour Christopher
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- Thomson Nicola
- Thrush Jessica
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- Triulzi Darrell
- Trodd Dawn
- Tsang Jennifer
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- Turgeon Alexis
- Turki Salah
- Turner Anne
- Turner Anne
- Turner-Bone Ian
- Turns Margaret
- Uddin Ruzena
- Udy Andrew
- Uyeki Tim
- Vaara Suvi
- Vahtera Annukka
- Vamplew Luke
- van Bentum Puijk Wilma
- van Bentum-Puijk Wilma
- van Bentum-Puijk Wilma
- van Beurden Marloes
- van de Veerdonk Frank
- van de Veerdonk Frank
- Van Der Heyden Kym
- van der Poll Tom
- van’t Hoff Willian
- Vates Jennifer
- Vautier Sarah
- Vazquez-Grande Gloria
- Venkatesh Bala
- Venkatesh Balasubramanian
- Venz Ellen
- Verlander Mark
- Verrier Nathalie
- Victor Saji
- Vieillard-Baron Antoine
- Voicu Sebastian
- Vowell Emma
- Vujaklija Brajković Ana
- Vuylsteke Alain
- Wagh Atul
- Walden Andrew
- Walker Rachel
- Walsh Joanne
- Walsh Tim
- Walsham James
- Ward Kathryn
- Warnock Majella
- Waterson Sharon
- Watkins Claire
- Watpool Irene
- Watters Malcolm
- Waugh Victoria
- Webb Steve
- Webb Steven A
- Wedd Steve
- Weismann Dirk
- Weissman Alexandra
- Wells Colin
- Welters Ingeborg
- Wetherill Bill
- Whelan Ruth
- Whileman Amanda
- Whitbread Jennifer
- White Hayden
- White Ian
- White Katie
- Whitehead Christina
- Wibrow Bradley
- Wigbers J
- Wilby Elizabeth
- Wild Laura
- Wild Laura
- Wilding Laura
- Wiley Daisy
- Wilhelmsen Elva
- Wilkinson Dean
- Willams Felicity
- Williams Alexandra
- Williams Erin
- Williams Hannah
- Williams Karen
- Williams Patricia
- Williams Patricia
- Williams Penny
- Williams Tony
- Williams Virginie
- Williamson Dawn
- Williamson James
- Wilson Karen
- Wilson Maggie
- Wiseman Sophie
- Wong Helen
- Wood Erica
- Wood Hannah
- Wood Tracy
- Woods Jane
- Woods Lindsey
- Worner Ruth
- Wren Jess
- Wren Lynn
- Wrey Brown Caroline
- Writing Committee for the REMAP-CAP Investigators
- Xavier Kugan
- Xia Le Tai Charlotte
- Yarad Elizabeth
- Yates David
- Young Chelsea
- Young Ian
- Young Meredith
- Young Paul
- Yusuff Hakeem
- Zaharia Miahela Florentina
- Zaidi Abbas
- Zaki Ahmed
- Zaman Mohsin
- Zammit Claire
- Zapalac Marija
- Zarychanski Ryan
- Zarychanski Ryan
- Zhao Xiao Bei
- Zinzoni Vanessa
- Zitter Letizia
- Đimoti Renata
- Publication venue
- JAMA: Journal of the American Medical Association
- Publication date
- 06/10/2020
- Field of study
Importance: Evidence regarding corticosteroid use for severe coronavirus disease 2019 (COVID-19) is limited. Objective: To determine whether hydrocortisone improves outcome for patients with severe COVID-19. Design, Setting, and Participants: An ongoing adaptive platform trial testing multiple interventions within multiple therapeutic domains, for example, antiviral agents, corticosteroids, or immunoglobulin. Between March 9 and June 17, 2020, 614 adult patients with suspected or confirmed COVID-19 were enrolled and randomized within at least 1 domain following admission to an intensive care unit (ICU) for respiratory or cardiovascular organ support at 121 sites in 8 countries. Of these, 403 were randomized to open-label interventions within the corticosteroid domain. The domain was halted after results from another trial were released. Follow-up ended August 12, 2020. Interventions: The corticosteroid domain randomized participants to a fixed 7-day course of intravenous hydrocortisone (50 mg or 100 mg every 6 hours) (n = 143), a shock-dependent course (50 mg every 6 hours when shock was clinically evident) (n = 152), or no hydrocortisone (n = 108). Main Outcomes and Measures: The primary end point was organ support-free days (days alive and free of ICU-based respiratory or cardiovascular support) within 21 days, where patients who died were assigned -1 day. The primary analysis was a bayesian cumulative logistic model that included all patients enrolled with severe COVID-19, adjusting for age, sex, site, region, time, assignment to interventions within other domains, and domain and intervention eligibility. Superiority was defined as the posterior probability of an odds ratio greater than 1 (threshold for trial conclusion of superiority >99%). Results: After excluding 19 participants who withdrew consent, there were 384 patients (mean age, 60 years; 29% female) randomized to the fixed-dose (n = 137), shock-dependent (n = 146), and no (n = 101) hydrocortisone groups; 379 (99%) completed the study and were included in the analysis. The mean age for the 3 groups ranged between 59.5 and 60.4 years; most patients were male (range, 70.6%-71.5%); mean body mass index ranged between 29.7 and 30.9; and patients receiving mechanical ventilation ranged between 50.0% and 63.5%. For the fixed-dose, shock-dependent, and no hydrocortisone groups, respectively, the median organ support-free days were 0 (IQR, -1 to 15), 0 (IQR, -1 to 13), and 0 (-1 to 11) days (composed of 30%, 26%, and 33% mortality rates and 11.5, 9.5, and 6 median organ support-free days among survivors). The median adjusted odds ratio and bayesian probability of superiority were 1.43 (95% credible interval, 0.91-2.27) and 93% for fixed-dose hydrocortisone, respectively, and were 1.22 (95% credible interval, 0.76-1.94) and 80% for shock-dependent hydrocortisone compared with no hydrocortisone. Serious adverse events were reported in 4 (3%), 5 (3%), and 1 (1%) patients in the fixed-dose, shock-dependent, and no hydrocortisone groups, respectively. Conclusions and Relevance: Among patients with severe COVID-19, treatment with a 7-day fixed-dose course of hydrocortisone or shock-dependent dosing of hydrocortisone, compared with no hydrocortisone, resulted in 93% and 80% probabilities of superiority with regard to the odds of improvement in organ support-free days within 21 days. However, the trial was stopped early and no treatment strategy met prespecified criteria for statistical superiority, precluding definitive conclusions. Trial Registration: ClinicalTrials.gov Identifier: NCT02735707
Lopinavir-ritonavir and hydroxychloroquine for critically ill patients with COVID-19: REMAP-CAP randomized controlled trial
- Author
- Aarti Nandani
- Abbas Zaidi
- Abby Waters
- Abhinav Gupta
- Abi Beane
- Abi Beane
- Abi Beane
- Abi Beane
- Abi Beane
- Abi Beane
- Achim Grünewaldt
- Adam Unsworth
- Adeeba Asghar
- Adeline Kintono
- Admad Daebis
- Adrian Buzgau
- Adrian Donnelly
- Adrian Regli
- Adrian Regli
- Adrien Pépin Lehalleur
- Agilan Kaliappan
- Ahilanandan Dushianthan
- Ahmed Bacha
- Ahmed Makky
- Ahmed Zaki
- Aibhilin O’Connor
- Aiman Mian
- Aine McCarthy
- Aisha Anjum
- Aisling O’Neill
- Ajay Raithatha
- Alain Robert
- Alain Vuylsteke
- Alan Tinmouth
- Alana Driscoll
- Alastair Somerville
- Albertine Smit
- Alex Barnard
- Alex Kazemi
- Alex Smith
- Alexandra Binnie
- Alexandra Edwards
- Alexandra Keen
- Alexandra McMillan
- Alexandra Weissman
- Alexandra Weissman
- Alexandra Williams
- Alexandros Cavayas
- Alexis F. Turgeon
- Alexis Turgeon
- Alexis Turgeon
- Alexis Turgeon
- Alexis Turgeon
- Alexis Turgeon
- Ali Al Amri
- Ali Ghamraoui
- Alice Harvey
- Alicia Waite
- Alisa M. Higgins
- Alison Ghosh
- Alison Potter
- Alison Quinn
- Alistair D. Nichol
- Alistair Hall
- Alistair Nichol
- Alistair Nichol
- Alistair Nichol
- Alistair Nichol
- Alistair Nichol
- Alistair Nichol
- Alistair Nichol
- Alistair Nichol
- Alistair Nichol
- Alistair Nichol
- Alistair Nichol
- Alistair Nichol
- Alistair Nichol
- Alistair Nichol
- Alistair Roy
- Allen Cheng
- Allen Cheng
- Allen Cheng
- Allen Cheng
- Allen Cheng
- Allen Cheng
- Allen Cheng
- Allison Bone
- Alma Gabriela Kosa
- Alsion Clinton
- Alvin Richards-Belle
- Amanda Cowton
- Amanda Hulley
- Amanda Sanderson
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- Amelia Butler
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- Amit Patel
- Amitaa Maharajh
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- Amro Katary
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- Ana Alegria
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- Anne Turner
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- Anthony Gordon
- Anthony Gordon
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- Anthony Gordon
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- Anthony Gordon
- Anthony Gordon
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- Tina Romagnuolo
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- Umesh Kadam
- Umesh Subbanna
- Upulee Pabasara
- Uwe Hoff
- Valerie J. Page
- Valli Ratnam
- Vanessa Linnett
- Vanessa Quick
- Vanessa Singh
- Vanessa Singh
- Vanessa Zinzoni
- Varun U. Shetty
- Vasanth Mariappa
- Vashish Deelchand
- Venika Manoharan
- Vera Juhaz
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- Victoria Waugh
- Vidya Kasipandian
- Vijay Jagannathan
- Viktor Kotarski
- Viktória Szőke
- Ville Pettilä
- Ville Pettilä
- Vincent Castelain
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- Vineela Mandadapu
- Vinodh Krishnamurthy
- Virginie Maxime
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- Vishwanath Biradar
- Vivian Lai
- Wendy Goddard
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- Wendy Sligl Steven Tong, Tim Uyeki van de Veerdonk Steve Webb
- Wenli Geng
- Werner Meermeier
- Wietske Bouwman
- William Bain
- William Dechert
- William Garrard
- William Van’t Hoff
- Wilma van Bentum Puijk
- Wilma van Bentum-Puijk
- Wilma van Bentum-Puijk
- Wilma van Bentum-Puijk
- Wilma van Bentum-Puijk
- Winningtom Ruiz
- Winston Cheung
- Wisam Al-Bassam
- Xia Jin
- Xiao Bei Zhao
- Xinyi Qiu
- Yahya Shehabi
- Yan Chen
- Yang Yang
- Yaseen Arabi
- Yaseen Arabi
- Yaseen Arabi
- Yaseen Arabi
- Yaseen Arabi
- Yaseen Arabi
- Yaseen M. Arabi
- Yaseen M. Arabi
- Yogesh Apte
- Yousuf Abusamra
- Yvette Ellis
- Yvonne Bland
- Yvonnick Boué
- Yvynne Croucher
- Zahra Bhimani
- Zahra Bhimani
- Zahra Bhimani
- Zahra Bhimani
- Zdravko Andric
- Ziortza Fernández de Pinedo Artaraz
- Zoe Borrill
- Zoe Daly
- Zoe Duke
- Zoe McQuilten
- Zoe McQuilten
- Zoe McQuilten
- Zoe Scott
- Zudin Puthucheary
- Zuhra Surti
- Zulfiqar Ali Umrani
- Ágnes Fazekas
- Ève Cloutier
- Publication venue
- Springer Science and Business Media LLC
- Publication date
- 12/07/2021
- Field of study
Lopinavir-ritonavir and hydroxychloroquine for critically ill patients with COVID-19: REMAP-CAP randomized controlled trial
- Author
- Abbass Hakam
- Abdeladim Lilia
- Abdelhady Hesham
- Abdelkharim Hussam
- Abdelrazik Marwa
- Abdukahil Sheryl Ann
- Abrahamson Gail
- Abusamra Yousuf
- Adams Ann
- Adams Peter
- Adhikari Neill
- Adhikari Neill
- Affleck Julia
- Agha Gloria Nwajei
- Agno Ronan
- Ahmad Norfaizan
- Ahmed Iram
- Ainscough Kate
- Ainscough Kate
- Ainscough Kate
- Ainsworth James
- Aitken Lindianne
- Akamp Ceren
- Al-Bassam Wisam
- Al-Beidh Farah
- Al-Beidh Farah
- Al-Beidh Farah
- Albert Martin
- Albrett Jonathan
- Alderman Meera
- Alegria Ana
- Alexander Brian
- Alexander Craig
- Alexander Peter
- Allan Angela
- Allen Barbara
- Allen Kezia
- Allen Louise
- Allibone Suzanne
- Alqahtani Samah
- Alswaidan Lolowa
- Amatya Sameena
- Amri Ali Al
- Anders Jeanette
- Anderson Thomas
- Andric Zdravko
- Angus Derek
- Angus Derek
- Angus Derek
- Angus Derek
- Angus Derek
- Angus Derek
- Angus Derek
- Angus Derek
- Angus Derek
- Angus Derek
- Angus Derek
- Angus Derek
- Angus Derek
- Angus Derek
- Angus Derek
- Anjum Aisha
- Ankert Juliane
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Annane Djillali
- Anstey Matthew
- Anstey Matthew
- Antcliffe David
- Aparicio Christelle
- Apte Yogesh
- Arabi Yaseen
- Arabi Yaseen
- Arabi Yaseen
- Arabi Yaseen
- Arabi Yaseen
- Arabi Yaseen
- Arabi Yaseen
- Arabi Yaseen
- Arachchige Malka Jayasinghe
- Aravindan Latha
- Archer Simon
- Aref Noah
- Arias Ana-Marie
- Arias Sonia Sousa
- Arishi Hatim
- Arnold Donald
- Aryal Diptesh
- Aryal Diptesh
- Aryal Diptesh
- Asghar Adeeba
- Aspinwall Angelique
- Atkins Stacey
- Attanayaka Udara
- Attokaran Antony
- Attwood Ben
- Austin Karen
- Austin Karen
- Austin Pauline
- Avard Bronwyn
- Awan Sidra
- Azaiz Amine
- Azzaui Harun Said
- Babel Jakša
- Babu Suresh
- Bacha Ahmed
- Badie Julio
- Bagshaw Sean
- Baig Nadia
- Baikady Ravishankar Rao
- Baillie Kenneth
- Baillie Kenneth
- Bain William
- Baker Evelyn
- Bakthavatsalam Dhanalakshmi
- Bamford Amy
- Bamford Peter
- Banach Dorota
- Bannard-Smith Jonathan
- Barbash Ian
- Barbazza Leanne
- Barber Russell
- Barbier François
- Barge Deborah
- Bari Sara
- Barnard Alex
- Barnes Nicky
- Baron Rebecca
- Bartholdy Roland
- Bartholomew Jazz
- Baršić Bruno
- Bashyal Archana
- Basile Kim
- Basile Kim
- Basile Kim
- Bass Frances
- Bassford Christopher
- Bastos Joana Margarida Pereira Sousa
- Bates Michelle
- Bates Samantha
- Batista Teresa Margarida Oliveira
- Bauchmuller Kris
- Bayne Madeleine
- Bean Sarah
- Beane Abi
- Beane Abi
- Beane Abi
- Beane Abi
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- Nichol Alistair
- Nichol Alistair
- Nichol Alistair
- Nichol Alistair
- Nichol Alistair
- Nichol Alistair
- Nichol Alistair
- Nichol Alistair
- Nichol Alistair
- Nichol Alistair
- Nichol Alistair
- Nichol Alistair
- Nicholier Tiphaine Barbarin
- Nicholls Guy
- Nicholson Andrew
- Nicholson Anne
- Nicholson Sarah
- Nickoleit-Bitzenberger Daniela
- Nierhaus Axel
- Nikitas Nikitas
- Nisar Mohammed
- Noble Harriet
- North Julie
- Nortje Jurgens
- Nourse Mary
- Novellas Neus Grau
- Nown Angie
- Nygren Maria
- Oakley Susan
- Oborska Aneta
- Oczkowski Simon
- Ogg Bethan
- Ogungbenro Kayode
- Okeke Tolu
- Okell Eleanor
- Okundaye Clementina
- Olatunji Shaanti
- Oliver Anne
- Ooi H.
- Orford Neil
- Orlikowski David
- Orr Katrina
- Orr Katrina
- Orr Katrina
- Osagie Rawlings
- Osinga Margreet
- Ostermann Marlies
- Oza Deepali
- O’brien Julie
- O’connor Aibhilin
- O’connor Anne
- O’connor Caroline
- O’connor Stephanie
- O’dwyer Michael
- O’flaherty Cliodhna
- O’halloran Sinead
- O’kane Cecilia
- O’kane Sinéad
- O’leary Ryan
- O’malley Laura
- O’neill Aisling
- O’reilly Joanna
- Pabasara Upulee
- Padmakumar Anand
- Page Valerie
- Pai Anirudda
- Pakats Mari Lis
- Pakou Glykeria
- Palermo Annamaria
- Palermo Annamaria
- Paneru Hem Raj
- Paneru Hem Raj
- Panjwani Ashok
- Panwar Rakshit
- Paramasivam Elankumaran
- Parekh Dhruv
- Parikh Harshel
- Parke Rachael
- Parke Rachael
- Parke Rachael
- Parke Rachael
- Parke Rachael
- Parke Rachael
- Parker Jane
- Parker Jane
- Parker Jane
- Parker Jane
- Parker Jane
- Parker Jane
- Parker Lorraine
- Parker Lorraine
- Parmar Dinesh
- Parry-Billings Karen
- Parsons Penny
- Patanwala Asad
- Patanwala Asad
- Patawala Asad
- Patch Sarah
- Patel Amit
- Patel Bijal
- Patel Brijesh
- Patel Kamal
- Patel Sanil
- Paterson David
- Patterson Lisa
- Paudel Pratibha
- Peake Sandra
- Peake Sandra
- Pearson Harriet
- Pearson Karen
- Pegler Suzannah
- Pellicano Susan
- Pereira Rita
- Pereira Tiago Nuno Alfaro Lima
- Perry Katherine
- Peters Anna Linda
- Peters Marco
- Peters Sam
- Peters Svenja
- Petros Sirak
- Pettilä Leena
- Pettilä Ville
- Pettilä Ville
- Phalod Gunjan
- Phalod Gunjan
- Philbin Jennifer
- Philips Barbara
- Phillips Barbara
- Phillips Louise
- Phillips Margaret
- Phull Mandeep-Kaur
- Phulpoto Masroor
- Pickkers Peter
- Pillai Suresh
- Pinder Meredith
- Pinnell Jez
- Pitts Sally
- Plantefeve Gaetan
- Pletz Mathias
- Pletz Mathias
- Pletz Mathias
- Pogreban Tatiana
- Pogson David
- Polgarova Petra
- Pomeroy Fiona
- Pooni Jagtar-Singh
- Porteous Rebecca
- Porter David
- Post Sophie
- Postlethwaite Kelly
- Potter Alison
- Pouplet Caroline
- Pourcine Franck
- Powell Elizabeth
- Prabakaran Raji Orat
- Prebeg Katharina
- Presneill Jeffrey
- Presneill Jeffrey
- Pridee Nicole
- Prinssen Anton
- Pritchard Kelly
- Prosser Lorraine Lewis
- Prout Rachel
- Pugh Richard
- Pulletz Mark
- Purandare Laura
- Purohit Dharam
- Purvis Sarah
- Puthucheary Zudin
- Puxty Kathryn
- Póvoa Pedro
- Qasim Eman Al
- Qiu Xinyi
- Quayle Rachael
- Quick Vanessa
- Quinn Alison
- Quinn Kevin
- Qureshi Hafiz
- Rad Laura
- Rademaker Emma
- Rademaker Emma
- Rai Namrata
- Raithatha Ajay
- Raj Ashok Sundar
- Ramali Mohamed
- Ramos Lidia
- Randell Georgina
- Rangan Ritika
- Ranganathan Lakshmi
- Ratnam Valli
- Rauniyar Rashmi
- Rawlins John
- Reay Michael
- Reddy Amie
- Reddy Harsha
- Reeve Brenda
- Regli Adrian
- Regli Adrian
- Reid Liadain
- Reid Liadain
- Reidy Bryan
- Reill Lorenz
- Rengers Els
- Reschreiter Henrik
- Rewa Oleksa
- Reynolds Claire
- Reynolds John
- Rhodes Jonathan
- Richards Suzanne
- Richards-Belle Alvin
- Richardson Angus
- Richecoeu Jack
- Riches Joanne
- Ricketts Daniel
- Riepe Ansgar
- Rikkert Linda
- Rimmer Dominic
- Ristimäki Sanna
- Ritzema Jenny
- Robert Alain
- Roberts David
- Roberts Eilir
- Robinson Matt
- Robinson Philip
- Roche Lisa
- Roche Lisa
- Rochwerg Bram
- Rodden Natalie
- Rodriguez Jorge
- Rodriguez Marina
- Roedl Kevin
- Rohde Gernot
- Rohde Gernot
- Rohde Gernot Gerhard Ulrich
- Rojo Roceld
- Romagnuolo Tina
- Roman Jaime Fernandez
- Romberg Birgit
- Rook Clare
- Rooney Kevin
- Roovers Noortje
- Rosa Arnold Dela
- Rosaroso Lace Paulyn
- Rosborough Brian
- Rose Steve
- Rostron Anthony
- Rowan Kathryn
- Rowan Kathryn
- Rowan Kathryn
- Rowan Kathryn
- Rowan Kathryn
- Rowan Kathryn
- Rowan Kathryn
- Rowe-Leete Louise
- Rowland Matthew
- Roy Alistair
- Roynon-Reed Anna
- Rudran Banu
- Ruiz Winningtom
- Runge Isabelle
- Russell Robert
- Ryalls Kim
- Ryan Donal
- Ryan Emily
- Ryan Lucy
- Sabelhaus Timo
- Sadera Girendra
- Sagnier Anne
- Salahuddin Nawal
- Salerno Tania
- Salhi Sara Nesrine
- Salisbury Sarah
- Sall Jas
- Salmon Charlotte
- Salmon Karen
- Saluzzio Romina Pepermans
- Sam Sally
- Sanderson Amanda
- Sandhu Gyan
- Sanghavi Ritesh
- Sanil Ashish
- Santamaria John
- Santos Filipa
- Santos Marlene
- Santos Marlene
- Santos Marlene
- Santos Marlene
- Saran Anita
- Sathe Sonia Arun
- Sathianathan Kushaharan
- Sathianathan Prasannakumari
- Saull Michelle
- Saunders Christina
- Saunders Christina
- Saunders Samantha
- Saxena Manoj
- Sayehli Cyrus
- Scanlon Jeremy James
- Scano Riccardo
- Schaaf Bernhard
- Scheepstra-Beukers Irma
- Schellaars Roel
- Schneider Francis
- Schoenling Andrew
- Schotsman Joost
- Schouten Jeroen
- Schreuder Gerwin
- Schuster-Bruce Martin
- Schutgens Roger
- Schweikert Sacha
- Schütze Bianka
- Scott Paula
- Scott Zoe
- Scully Michael
- Seaman Rebecca
- Seidu Fatima
- Sekiwala Rose Nalumansi
- Sellers Katharine
- Selvamoni Selvin
- Senya Ho Jan
- Seppelt Ian
- Seppelt Ian
- Serri Karim
- Sever Helena
- Seymour Christopher
- Seymour Christopher
- Seymour Christopher
- Seymour Christopher
- Seymour Christopher
- Seymour Christopher
- Seymour Christopher
- Seymour Christopher
- Shah Asim
- Shah Faraaz
- Shahid Tasnin
- Shaikh Mohiuddin
- Shankar-Hari Manu
- Shankar-Hari Manu
- Shankar-Hari Manu
- Sharratt Paula
- Shaw David
- Shaw Deborah
- Shaw Joanne
- Shearer Audrey
- Sheath Ben
- Sheffield Johnathan
- Shehabi Yahya
- Shekar Kiran
- Shelton Sarah
- Shetty Varun
- Shirley Kim
- Shovelton Charmaine
- Shrestha Tapaswi
- Shuker Karen
- Shyamsundar Murali
- Siami Shidasp
- Siddiq Shoaib
- Siddiqui Atif
- Siddiqui Atif
- Sidéris Georgios
- Siewerski Chris
- Silversides Jon
- Sim Malcolm
- Simmonds Catherine
- Simons Koen
- Simpson Benjamin
- Simpson Joanna
- Simpson Scott
- Sinclair Julie-Ann
- Singh Jayaprakash
- Singh Rajeev
- Singh Vanessa
- Singh Vanessa
- Singleton Jo
- Sinha Pratik
- Skinner Denise
- Skinner Tabitha
- Slade Heather
- Sligl Wendy
- Small Charlotte
- Smallwood Andrew
- Smee Joanna
- Smit Albertine
- Smith Alex
- Smith Amy Collins Emma
- Smith Catherine
- Smith John
- Smith Judith
- Smith Julie
- Smith Kirstie
- Smith Matthew
- Smith Roger
- Smith Simon
- Smith Tim
- Smuts Sara
- Smyth Kirsty
- Smyth Michelle
- Smyth Michelle
- Smyth Naoise
- Soar Natalie
- Solesbury Amanda
- Somerville Alastair
- Song Rima
- Soukup Jens
- Southern David
- Southin Sara
- Spain Sandra
- Speight Holly
- Spencer Thomas
- Spittle Nick
- Spivey Michael
- Sprinckmoller Stefan
- Squires Rebecca
- Stammers Katie
- Stanciu Delia
- Stanworth Simon
- Stanworth Simon
- Starke Lisa
- Sterba Martin
- Stevenson Lesley
- Stewart Richard
- Subbanna Umesh
- Sukuraman Anila
- Summers Charlotte
- Sundaran Dhinesh
- Surti Zuhra
- Sutherland Helen
- Sutterlin Laetitia
- Sutton Joanne
- Sutu Mihaela
- Swabe Jacqueline
- Swaidan Lolowa Al
- Sweet Katie
- Sy Eric
- Szakmany Tamas
- Szakmany Tamas
- Szigligeti Gábor
- Szőke Viktória
- Tallott Mandy
- Tate Margaret Louise
- Tatham Kate Colette
- Taylor Holly
- Templeton Maie
- Thomas Amy
- Thomas Emma
- Thomas Helen
- Thomas Matt
- Thomas Matthew
- Thompson Patricia
- Thompson Taylor
- Thomson Nicola
- Thrush Jessica
- Thrush Jessica
- Tilney Emma
- Tinmouth Alan
- Tirot Patrice
- Tjan Dave
- Tlayjeh Haytham
- Tolppa Timo
- Tolppa Timo
- Tolppa Timo
- Tomlinson Helen
- Tong Steve
- Tong Steven
- Tooley Joe
- Totzke Juliane
- Touma Omar
- Towns Miriam
- Trapani Tony
- Trapani Tony
- Trask Kara
- Traverse Eleanor
- Tridente Ascanio
- Triulzi Darrell
- Trues Estefania
- Tsakiridou Kyriaki
- Tsang Jennifer
- Tsinaslanidis Georgios
- Tuckwell Caroline
- Tully Redmond
- Tully Riona
- Tung Raymond
- Turgeon Alexis
- Turgeon Alexis
- Turgeon Alexis
- Turgeon Alexis
- Turgeon Alexis
- Turgeon Alexis
- Turki Salah
- Turner Anne
- Turner Anne
- Turner Anne
- Turner Anne
- Turner Keri
- Turner Keri
- Turner-Bone Ian
- Udayanga Ishara
- Uddin Ruzena
- Udy Andrew
- Udy Andrew
- Umrani Zulfiqar Ali
- Unsworth Adam
- Uyeki Tim
- Uyeki Tim
- Vaara Suvi
- Vaduganathan Muthiah
- Vahtera Annukka
- Vale Cassandra
- Valentine Eliza
- Vamplew Luke
- van Bentum Puijk Wilma
- van Bentum-Puijk Wilma
- van Bentum-Puijk Wilma
- van Bentum-Puijk Wilma
- van Bentum-Puijk Wilma
- van Beurden Marloes
- van Bree Sjoerd
- van de Veerdonk Steve Webb Wendy Sligl, Steven Tong, Tim Uyeki
- van de Veerdonk Frank
- van de Veerdonk Frank
- van de Veerdonk Frank
- van de Veerdonk Frank Leo
- van den Oever Huub
- van der Eng Hetty
- van der Heyden Kymbalee
- van der Poll Tom
- van der Wekken Ruben
- van Dijk Diederik
- van Gelder Fiona
- van Gulik Laura
- van Hout Denise
- van Iperen Mark
- van Kimmenade Roland
- van Zanten Arthur
- van Zuylen Tamara
- Vautier Sarah
- Vazquez-Grande Gloria
- Vazquez-Grande Gloria
- Veenith Tonny
- Venkatesh Bala
- Venz Ellen
- Verlander Mark
- Vermassen Joris
- Vermeiren Daisy
- Verrier Nathalie
- Vertue Mark
- Victor Saji
- Vieillard-Baron Antoine
- Vignesh C.
- Vincent Rachel
- Virdee Satwinder
- Vita Tina
- Vodovar Dominique
- Voicu Sebastian
- Voiriot Guillaume
- Vowell Emma
- Vuylsteke Alain
- Wagh Atul
- Wahl Nadine
- Waite Alicia
- Walden Andrew
- Walker Rachel
- Walker Susan
- Walsh Tim
- Walsham James
- Wang Shu Fang
- Ward Geraldine
- Ward Kathryn
- Warnapura Loku Chamara
- Warnock Majella
- Waters Abby
- Waterson Sharon
- Watkins Claire
- Watpool Irene
- Watters Malcolm
- Watts Angela
- Waugh Victoria
- Webb Steve
- Webb Steve
- Webb Steve
- Webb Steve
- Webb Steve
- Webb Steve
- Webb Steve
- Webb Steve
- Webb Steve
- Webb Steve
- Webb Steve
- Webb Steve
- Webb Steve
- Webb Steve
- Webb Steve
- Webb Steve
- Webb Steve
- Webb Steven
- Weerasinghe Thanuja
- Weismann Dirk
- Weissman Alexandra
- Weissman Alexandra
- Wells Colin
- Welters Ingeborg
- Wetherill Bill
- Wetzold Richard
- Whileman Amanda
- Whitbread Jennifer
- White Hayden
- White Ian
- White Katie
- Whitehead Christina
- Whitehouse Tony
- Wibrow Bradley
- Wieder Talia
- Wigbers Jeanette
- Wilby Elizabeth
- Wilcox Elizabeth
- Wilcox Louise
- Wild Helen
- Wild Laura
- Wild Nicholas Cowley Laura
- Wilding Karen
- Wilding Laura
- Wiles Matt
- Wiley Daisy
- Wilhelmsen Elva
- Wilkinson Dean
- Willams Felicity
- Williams Alexandra
- Williams Angharad
- Williams Anna
- Williams Erin
- Williams Gemma
- Williams Hannah
- Williams Karen
- Williams Patricia
- Williams Patricia
- Williams Penny
- Williams Tony
- Williams Virginie
- Williamson Dawn
- Williamson James
- Willson Jayne
- Wilson Craig
- Wilson Maggie
- Wise Matt
- Wiseman Sophie
- Wong Helen
- Wood Erica
- Wood Hannah
- Wood Hannah
- Wood Tracy
- Woods Jane
- Woods Lindsey
- Woollett Melissa
- Worner Ruth
- Wren Jess
- Wren Lynn
- Wylie Katharine
- Xavier Kugan
- Yang Yang
- Yarad Elizabeth
- Yates David
- Young Chelsea
- Young Ian
- Young Meredith
- Young Paul
- Young Paul
- Youngstein Taryn
- Yu Haili
- Yusuff Hakeem
- Zaharia Mihaela Florentina
- Zaidi Abbas
- Zaki Ahmed
- Zaman Mohsin
- Zammit Claire
- Zapalac Marija
- Zarychanski Ryan
- Zarychanski Ryan
- Zarychanski Ryan
- Zarychanski Ryan
- Zarychanski Ryan
- Zarychanski Ryan
- Zarychanski Ryan
- Zarychanski Ryan
- Zhao Xiao Bei
- Zinzoni Vanessa
- Zitter Letizia
- Đimoti Renata
- Publication venue
- Springer Verlag
- Publication date
- 12/07/2021
- Field of study
International audienc
