POTENSI KANDUNGAN GIZI DEDAK PADI DI TIGA SENTRAL PRODUKSI PADI

Penelitian ini bertujuan untuk mengetahu i kandungan gizi dedak padi dari healer di beberapa kabupaten di Sumatra Barat ( Padang p ariaman, Solok dan Tanah datar ) . Penelitian dilakukan menggunakan metode survey dan analisis laboratorium. Data yang dikumpulkan adalah data primer dan sekunder. Data primer berupa pengamatan dan wawancara langsung di tiga daerah dengan menggunakan Rancangan Acak Lengkap ( RAL ) yang terdiri da ri 3 (t iga) perlakun berdasarkan daerah yaitu A 1 ( Tanah datar ), A2 ( Solok ) , A3 ( Padang pariaman ) dengan 6 (enam) ulangan berdasarkan kecamatan yaitu Batipuah , Lima kaum, Pariangan, Rambatan, Padang gantiang, Sungai ameh , Lembang jaya , 50 kota di atas, Payuang sakaki, Gunuang talang, 3 lurah, Lembang kumanti, P atamuan, Sungai geringging, Pad a ng sagu, 2x11 enam lingkungan, Sungai limau, V11 koto sungai sariak. Parameter yang diamati adalah kandungan dedak antara lain : Bahan kering (BK) , Abu , Serat kasar (SK), Protein kasar (PK) , dan Lemak kasar (LK) . Hasil pene litian menunjukan bahwa perlakuan tidak memberikan pengaruh yang nyata (P>0,05) terhadap k andungan bahan kering, abu, protein kasar, lemak kasar, dan serat kasar . Kualitas dedak padi di daerah padang pariaman memiliki kandungan BK dan abu tertinggi dari da erah lain nya. Sedangkan kandungan SK dan PK tertinggi terdapat di daerah tanah datar dan daerah solok memiliki kandungan BK, Abu, SK, PK, dan LK terendah. Penelitian ini dapat disimpulkan bahwa dedak padi di daerah Tanah datar memiliki kualitas yang bai k dari daerah Solok dan Padang P ariaman. Kata kunci : Kandungan Gizi, Dedak Padi, Sentral Produks

Preliminary in vivo investigation of the mesenchymal stromal cell secretome as a novel treatment for methicillin-resistant Staphylococcus aureus in equine skin wounds

ObjectiveWe aimed to study the antimicrobial and pro-healing potential of equine mesenchymal stromal cell secreted products (i.e. secretome), collected as conditioned media (mesenchymal stromal cell-conditioned media, MSC CM), in a novel in vivo model of methicillin-resistant Staphylococcus aureus (MRSA)-inoculated equine thorax wounds.Study designProspective in vivo study.AnimalsTwo Thoroughbred geldings.MethodsSix full-thickness cutaneous wounds were created bilaterally on the dorsal thorax of two horses (n = 12 wounds/horse). Wounds on the left thoraces were inoculated with MRSA on day 0. All wounds were then treated with either mupirocin ointment, MSC CM, or vehicle control (n = 4 wounds per group) once daily for 3 days. Photographs were taken to quantify wound scores and sizes, as well as samples to determine bacterial colony forming units (CFUs), at days 0, 1, 2, 3, 7, 14, 21, and 28. The wound edge was biopsied on days 0, 7, and 28, and scored histologically.ResultsInoculated wounds had more bacterial CFUs at day 1 (p < .0001) and were larger in size at day 28 (p = .0009) than noninoculated wounds. Mupirocin-treated wounds were smaller than MSC CM and vehicle control-treated wounds at day 28 (p = .003). Mesenchymal stromal cell-conditioned media did not affect CFU numbers in inoculated and noninoculated wounds. Moreover, MSC CM did not affect the parameters of wound size or gross or microscopic wound scores over time.ConclusionMesenchymal stromal cell-conditioned media did not exhibit antimicrobial or pro-healing properties in the current study; however, the in vivo model of inoculated equine thorax wounds requires further optimization.Clinical significanceThis pilot study contributes to a growing understanding of the equine MSC secretome as an antimicrobial and pro-healing therapeutic for equine wounds

Epstein-Barr virus as promoter of Lemierre syndrome: systematic literature review

Purpose: To investigate a possible link between acute Epstein-Barr virus infection and Lemierre syndrome, a rare yet life-threatening infection. Methods: A systematic review was conducted adhering to the 2020 Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Diagnosis criteria for Lemierre syndrome were established, and data extraction encompassed demographic data, clinical, and laboratory information. Results: Out of 985 initially identified papers, 132 articles were selected for the final analysis. They reported on 151 cases of Lemierre syndrome (76 female and 75 male patients with a median of 18 years) alongside interpretable results for Epstein-Barr virus serology. Among these, 38 cases (25%) tested positive for acute Epstein-Barr virus serology. There were no differences in terms of age, sex, or Fusobacterium presence between the serologically positive and negative groups. Conversely, instances of cervical thrombophlebitis and pulmonary complications were significantly higher (P = 0.0001) among those testing negative. The disease course was lethal in one case for each of the two groups. Conclusions: This analysis provides evidence of an association between acute Epstein-Barr virus infection and Lemierre syndrome. Raising awareness of this link within the medical community is desirable

Deployment of finite-stage Markov decision processes for inventory management solutions in enterprise restructuring, Chapter 13

The decision making process is becoming very complex, especially when it comes to the problem of enterprise restructuring. Intelligent solutions have to be utilized in order to cope efficiently with this issue. For this purpose the model for enterprise restructuring, named as COMPASS was developed. It aims to systematise the complex process of enterprise restructuring and to attach appropriate methods in the key decision making points, supporting the industry praxis with robust, scientifically founded, but practical and easy to use methods/tools. COMPASS is meant to be under continuous development. Now, the improvement of the process of generation of success factors (as a dominantly heuristic activity) and the optimization of the simulation process are the focal points. Here, the improvement of the generation of success factors through an application of finite-stage Markov decision processes (MDP) in the inventory problem is introduced. The objective is to find the optimal inventory policy and to determine the utility function. MDP are a flexible technique for stochastic and dynamic optimization problems and provide a powerful tool for optimizing performance in very different areas and their application in inventory management is only one of the examples

Application of finite-stage Markov decision processes in policy determination for employees’motivation

Enterprise restructuring is becoming very important in today’s dynamic environment. In that direction systematic and efficient approach concerning the enterprise restructuring is more than important for gaining competitiveness of the enterprises. In this article, one methodology for enterprise restructuring (COMPASS) is briefly presented. It is an open methodology, meaning that it is giving the frames of the restructuring process and it allows implementation of various additional methods, tools, etc. We are continually trying to upgrade this methodology with sophisticated but easy to use methods that will improve its usability. One very important aspect of the restructuring is coping with the resistance to changing. Here, the utilization of Markov decision processes considering the policy determination for employees’ motivation is presented. The focus will be on solution techniques for the finite stage problems