Changes in settlement pattern and culture - the process of down-hill migration in Tula, Bauchi State

The process of down-hill migration of the Tula people started during the 1920s and has not yet finished. The resulting present situation might give information how far terraces play any role in the economy, ecology and ideology of the Tula. Approaching this question from a socio-agricultural point of view some facts which indicate the pertaining or overcoming of traditional structures will be presented. In the following the land tenure system, the adoption of innovations and the role of women in agriculture will be discussed comparatively for Tula Wange and Tula Baule on the plateau, Fantami, which is generated by down-hill dwellers of Tula Wange, with its more or less bad farming conditions on shallow sandy soils and Kaltin, where the down migrants of Tula Baule settle in a more fertile area. Tula Wange numbers around 2000 households, Baule 1000, Fantami about 200 and Kaltin 350 of which the sample survey includes 15% in the plateau sites and 25% in the plain settlements

National Culture\u27s Impact on Effectiveness of Supply Chain Disruption Management

The purpose of this research is to understand the national cultural antecedents that may help explain differences in supply chain disruptions mitigation abilities of companies from different countries. An analysis of survey data on disruption planning and response collected from various organizations worldwide was performed using weighted least square regression and factor analysis. We find that culture influences disruption planning and response. Statistical findings suggest that differences in disruption planning and response abilities between companies from different countries could be partly attributed to national culture. All five Hofstede’s dimensions of national culture, i.e., Power Distance, Individualism, Masculinity, Uncertainty Avoidance, and Long-term Orientation were shown to have a significant positive effect on disruption planning and response. National cultural dimensions and economic status of a country could be effectively used to predict disruption planning and response abilities of companies in various countries. Managers could benefit from our research as it could help them assess disruptions mitigation abilities of their partners located in other countries. Increasing international trade and globalization of supply chains accentuate the importance of our research

La perception de l'environnement et les migrations chez les pasteurs Peuls du Nigeria, Burkina Faso et Bénin

Dans les sociétés peules, des migrations de toutes dimensions jouent traditionnellement un rôle très important. Elles sont le résultat d’un processus complexe de prise de décision. Notre contribution vise à fournir des informations sur les motifs qui influencent ces décisions, et à partir de quels concepts ces motifs sont générés. Un élément central dans ce processus est l’environnement. S’il y a quelque peu un environnement ou une culture peule homogène, il n’y a cependant pas de conception peule de l’environnement. Leur conception est modifiée lors de chaque intégration des Peuls dans un nouvel environnement. Migrer signifie se rendre dans un nouvel environnement, où les concepts existants doivent par conséquent être adaptés aux nouvelles conditions. Par la suite, nous allons montrer à l’exemple des Peuls agropastoraux de différents milieux naturels et sociaux du Burkina Faso, Bénin et Nigeria dans quelle mesure les connaissances de l’environnement peuvent influencer les décisions migratoires. A l’exemple de la végétation, on examinera à travers quels concepts cet environnement, plus précisément l’environnement physique, est classifié et évalué. Finalement il sera présenté comment les migrations influencent les concepts environnementaux et comment ceux-là se reflètent dans la langue

A framework for examining accountability and value for money in the UK's private finance initiative

This paper seeks to develop a system for evaluating the implications of accountability and value-for-money (VFM) decisions in private finance initiative (PFI) projects from initiation through set-up, implementation and internal and external monitoring. By reviewing the extant literature on accountability and VFM, a model is developed for evaluating the implications of various types of accountability and VFM decisions on PFI projects. Most previous studies have considered either the accountability or VFM at the projects' initial stages; little attention has been paid to the interrelationship between accountability and VFM issues in the evaluation of various PFI processes. This paper addresses these lacunae in the literature

Appendix tumors in the era of laparoscopic appendectomy

Background: The safety of laparoscopic appendectomy for the management of incidentally discovered appendiceal tumors has not yet been established. Methods: Appendiceal tumor cases managed by laparoscopy or laparotomy over a 10-year period were reviewed. Results: The pathological diagnoses were 23 carcinoid and 20 cancerous lesions. The median patient ages were 36 and 69years, respectively, for carcinoid and other tumors (p < 0.05). Acute appendicitis was present in 70% of carcinoid cases and 35% of other tumors (p < 0.05). Eight patients with carcinoid tumors were operated on by laparoscopy, whereas 15 underwent laparotomy. Laparoscopic and open procedures were performed in three and 17 patients with cancerous lesions, respectively. Invaded surgical margins were seen after laparoscopy in 20% of patients and open surgery in 6%. Synchronous colon carcinoma was detected in 14% of the patients with an appendix neoplasm. The 5-year survival rates were similar after both laparoscopic and open appendectomy for either carcinoid or other tumors. Conclusion: Laparoscopic appendectomy for appendiceal tumors seems to have a slightly higher rate of inadequate resection. However, it is not associated with a significantly worse patient prognosis than open appendectom

India's dilemma in the Arab spring

How can India’s reactions to the Arab Spring be explained? Why did India react differently to the Libyan and Syrian cases? How do India’s responses justify its aspiration to take an active role in an emerging multilateral international order? This paper attempts to answer these questions by analyzing India’s major interests in the MENA region. India’s voting behavior vis-à-vis the UN resolutions during its Security Council tenure offers a critical empirical baseline supporting this analysis. The paper highlights that India’s traditional foreign policy based on the non-alignment and non-interventionist principles have been driven by its economy, energy and diaspora-related interests towards the MENA region. The Arab Spring created a dilemma for India in its foreign policy making and a partial deviation from the traditional foreign policy approach, especially in multilateral platforms. Despite these challenges, this paper argues that India successfully resisted the wave of the Arab Spring

Autologous anti-SOX2 antibody responses reflect intensity but not frequency of antigen expression in small cell lung cancer

Background: Anti-SOX2 antibody responses are observed in about 10 to 20% of small cell lung cancer (SCLC) patients. The aim of this study was to determine whether such responses reflect a particular pattern of SOX2 protein expression in the tumor and whether this pattern associates with clinical outcome. Methods. Paraffin embedded tumor tissues, obtained from SCLC patients who had no evidence of paraneoplastic autoimmune degeneration, were evaluated for SOX2 expression by immunohistochemistry for both intensity and extent of staining. Sera from the same patients were tested for autologous antibodies against recombinant SOX2 by enzyme-linked immunosorbent assay (ELISA). Correlates between overall survival and various clinical parameters including SOX2 staining and serology were determined. Results: SOX2 protein expression was observed in tumor tissue in 89% of patients. Seventeen patients (29%) were seropositive for SOX2 antibodies and, in contrast to SOX2 staining, the presence of antibody correlated with limited disease stage (p = 0.05). SOX2 seropositivity showed a significant association with the intensity of SOX2 staining in the tumor (p = 0.02) but not with the frequency of SOX2 expressing cells. Conclusion: Anti-SOX2 antibodies associate with better prognosis (limited stage disease) while SOX2 protein expression does not; similar to reports from some earlier studies. Our data provides an explanation for this seemingly contrasting data for the first time as SOX2 antibodies can be observed in patients whose tumors contain relatively few but strongly staining cells, thus supporting the possible presence of active immune-surveillance and immune-editing targeting SOX2 protein in this tumor type. © 2014 Atakan et al.; licensee BioMed Central Ltd

Expression of Plakophilins (PKP1, PKP2, and PKP3) in Gastric Cancers

BACKGROUND: The importance of cell-cell junction proteins (including armadillo proteins) in tumor biology is known, but limited with regard to plakophilins. We explored the relationship between plakophilins (PKP1, PKP2, PKP3) to gastric cancer via immunohistochemical techniques. METHODS: We compared the immunohistochemistry of PKPs in 34 gastric adenocarcinomas and 20 normal gastric tissues. RESULTS: In gastric cancer, PKP1 expression was unchanged but PKP2 and PKP3 were significantly decreased as compared to normal controls. There was no observable clinical association with PKP1 or PKP2 expression; however, low PKP3 level and poor prognosis appeared to correlate with regards to node number and tumor stage. The mean disease-free survival (DFS) was 38 ± 3 months (range: 32 - 44) and mean overall survival (OS) 42 ± 4 months (range: 38 - 50). Decreased PKP2 appeared to negatively impact DFS. CONCLUSION: Decreased PKP2 and PKP3 may be early prognostic markers and loss of PKP3 expression during gastric carcinoma progression may indicate an invasive phenotype

Pulmonary tumor thrombotic microangiopathy: a systematic review.

Pulmonary tumor thrombotic microangiopathy (PTTM) is a fatal disease process in which pulmonary hypertension (PH) develops in the setting of malignancy. The purpose of this study is to present a detailed analysis of cases of PTTM reported in literature in the hopes of achieving more ante-mortem diagnoses. We conducted a systematic review of currently published and available cases of PTTM by searching the term "pulmonary tumor thrombotic microangiopathy" on the Pubmed.gov database. Seventy-nine publications were included consisting of 160 unique cases of PTTM. The most commonly reported malignancy was gastric adenocarcinoma (94 cases, 59%). Cough and dyspnea were reported in 61 (85%) and 102 (94%) cases, respectively. Hypoxemia was reported in 96 cases (95%). Elevation in D-dimer was noted in 36 cases (95%), presence of anemia in 32 cases (84%), and thrombocytopenia in 30 cases (77%). Common findings on chest computed tomography (CT) included ground-glass opacities (GGO) in 28 cases (82%) and nodules in 24 cases (86%). PH on echocardiography was noted in 59 cases (89%) with an average right ventricular systolic pressure of 71 mmHg. Common features of PTTM that are reported across the published literature include presence of dyspnea and cough, hypoxemia, with abnormal CT findings of GGO, nodules, and mediastinal/hilar lymphadenopathy, and PH. PTTM is a universally fatal disease process and this analysis provides a detailed examination of all the available published data that may help clinicians establish an earlier diagnosis of PTTM