357 research outputs found
Are EU spatial ex ante coexistence regulations proportional?
The EU is currently struggling to implement coherent coexistence regulations on genetically modified (GM) and non-GM crops in all member states. While it stresses that any approach needs to be “proportionate to the aim of achieving coexistence”, very few studies have actually attempted to assess whether the proposed spatial ex ante coexistence regulations (SEACERs) satisfy this proportionality condition. In this article, we define proportionality as a functional relationship which is weakly increasing in the incentives for coexistence. We propose a spatial framework based on an existing landscape and introduce the new concept of shadow factor as a measure for the opportunity costs induced by SEACERs. This enables comparing the proportionality of (i) rigid SEACERs which are based on large isolation distances imposed on GM farmers versus (ii) flexible SEACERs based on pollen barrier agreements between neighboring farmers. Our theoretical and empirical findings argue for flexibility as rigid SEACERs violate the proportionality condition and, hence, are not consistent with the objectives of the EU.policy analysis, GIS, shadow factor, Agricultural and Food Policy, Crop Production/Industries,
Economics of spatial coexistence of genetically modified and conventional crops: Oilseed rape in Central France
Europe is currently struggling to implement coherent coexistence regulations on genetically modified (GM) and non-GM crops in all EU Member States. We conduct simulations with the software ArcView® on a GIS dataset of a hypothetical case of GM herbicide tolerant oilseed rape cultivation in Central France. Our findings show that rigid coexistence rules, such as large distance requirements, may impose a severe burden on GM crop production in Europe. These rules are not proportional to the farmers’ basic incentives for coexistence and hence not consistent with the objectives of the European Commission. More alarming, we show that in densely planted areas a domino-effect may occur. This effect raises coexistence costs and even adds to the non-proportionality of rigid coexistence regulations. Instead, we show that flexible measures would be preferable since they are proportional to the incentives for coexistence and, hence, less counterproductive for European agriculture.regulation, GIS modelling, domino-effect, Crop Production/Industries,
Chronic symptoms in a representative sample of community-dwelling older people: a cross-sectional study in Switzerland.
The burden of multiple diagnoses is well documented in older people, but less is known about chronic symptoms, many of which are even not brought to medical attention. This study aimed to determine the prevalence of chronic symptoms, their relationships with disability in basic activities of daily living (BADL) and quality of life (QoL), and their public health impact.
A large cross-sectional population-based study.
Community in 2 regions of French-speaking Switzerland.
Community-dwelling older adults aged 68 years and older in 2011 (N=5300).
Disability in BADL defined as difficulty or help needed with any of dressing, bathing, eating, getting in/out of bed or an arm chair, and using the toilet. Overall QoL dichotomised as favourable (ie, excellent or very good) or unfavourable (ie, good, fair or poor). Disturbance by any of the following 14 chronic symptoms for at least 6 months: joint pain, back pain, chest pain, dyspnoea, persistent cough, swollen legs, memory gaps, difficulty concentrating, difficulty making decisions, dizziness/vertigo, skin problems, stomach/intestine problems, urinary incontinence and impaired sexual life.
Only 17.1% of participants did not report being disturbed by any of these chronic symptoms. Weighted prevalence ranged from 3.1% (chest pain) to 47.7% (joint pain). Most chronic symptoms were significantly associated with disability in BADL or unfavourable QoL, with substantial gender differences. The number of chronic symptoms was significantly associated with disability in BADL and unfavourable QoL, with gradients suggesting dose-response relationships. Joint pain and back pain had the highest population attributable fractions.
Chronic symptoms are highly prevalent in older people, and are associated with disability in BADL and unfavourable QoL, particularly when multiple chronic symptoms co-occur. Owing to their high public health impact, musculoskeletal chronic symptoms represent good targets for preventive interventions
Muscle co‐activation across activities of daily living in individuals with knee osteoarthritis
Thermo-mechanical analysis of dental silicone polymers
Soft lining materials are used to replace the inner surface of a conventional complete denture, especially for weak elderly patients, with delicate health who cannot tolerate the hard acrylic denture base. Most of these patients have fragile supporting mucosa, excessive residual ridge resorption, particularly on the mandibular arch. The application of a soft liner to the mandibular denture allows absorbing impact forces during mastication and relieving oral mucosa. Actually, the silicone rubbers constitute the main family of commercialised soft lining materials. This study was conducted to understand the relationships between the mechanical properties and the physical structure of polysiloxanes. For this purpose, a series of polysiloxanes of various chemical compositions have been investigated. The evolution of their physical structure as a function of temperature has been followed by differential scanning calorimetry (DSC). In order to facilitate comparisons, the mechanical modulus has been analysed upon the same heating rate using dynamic mechanical analysis (DMA). Polysiloxanes actually commercialised as soft denture liners are three-dimensional networks: the flexibility of chains allows a crystalline organisation in an amorphous phase leading to the low value of the shear modulus. The dynamic mechanical analysis shows that they are used in the rubbery state. So, polysiloxanes have steady mechanical properties during physiological utilisation
Does a SLAP lesion affect shoulder muscle recruitment as measured by EMG activity during a rugby tackle?
Background: The study objective was to assess the influence of a SLAP lesion on onset of EMG activity in shoulder muscles during a front on rugby football tackle within professional rugby players.
Methods: Mixed cross-sectional study evaluating between and within group differences in EMG onset times. Testing was carried out within the physiotherapy department of a university sports medicine clinic. The test group consisted of 7 players with clinically diagnosed SLAP lesions, later verified on arthroscopy. The reference group consisted of 15 uninjured and full time professional rugby players from within the same playing squad. Controlled tackles were performed against a tackle dummy. Onset of EMG activity was assessed from surface EMG of Pectorialis Major, Biceps Brachii, Latissimus Dorsi, Serratus Anterior and Infraspinatus muscles relative to time of impact. Analysis of differences in activation timing between muscles and limbs (injured versus non-injured side and non injured side versus matched reference group).
Results: Serratus Anterior was activated prior to all other muscles in all (P = 0.001-0.03) subjects. In the SLAP
injured shoulder Biceps was activated later than in the non-injured side. Onset times of all muscles of the noninjured shoulder in the injured player were consistently earlier compared with the reference group. Whereas, within
the injured shoulder, all muscle activation timings were later than in the reference group.
Conclusions: This study shows that in shoulders with a SLAP lesion there is a trend towards delay in activation time of Biceps and other muscles with the exception of an associated earlier onset of activation of Serratus anterior, possibly due to a coping strategy to protect glenohumeral stability and thoraco-scapular stability. This
trend was not statistically significant in all cases
Sexual selection protects against extinction
Reproduction through sex carries substantial costs, mainly because only half of sexual adults produce offspring. It has been theorised that these costs could be countered if sex allows sexual selection to clear the universal fitness constraint of mutation load. Under sexual selection, competition between (usually) males, and mate choice by (usually) females create important intraspecific filters for reproductive success, so that only a subset of males gains paternity. If reproductive success under sexual selection is dependent on individual condition, which depends on mutation load, then sexually selected filtering through ‘genic capture’ could offset the costs of sex because it provides genetic benefits to populations. Here, we test this theory experimentally by comparing whether populations with histories of strong versus weak sexual selection purge mutation load and resist extinction differently. After evolving replicate populations of the flour beetle Tribolium castaneum for ~7 years under conditions that differed solely in the strengths of sexual selection, we revealed mutation load using inbreeding. Lineages from populations that had previously experienced strong sexual selection were resilient to extinction and maintained fitness under inbreeding, with some families continuing to survive after 20 generations of sib × sib mating. By contrast, lineages derived from populations that experienced weak or non-existent sexual selection showed rapid fitness declines under inbreeding, and all were extinct after generation 10. Multiple mutations across the genome with individually small effects can be difficult to clear, yet sum to a significant fitness load; our findings reveal that sexual selection reduces this load, improving population viability in the face of genetic stress
Systems approaches to innovation in pest management: reflections and lessons learned from an integrated research program on parasitic weeds in rice
This paper provides a retrospective look at a systems-oriented research program, on the increasing occurrence of parasitic weeds in rainfed rice in sub-Saharan Africa, to qualitatively assess merits and identify challenges of such approach. We gained a broad contextual overview of the problem and different stakeholders' roles, which enabled identification of entry points for innovations in parasitic weed management. At the crop level parasitic weed infestation is associated with poor soil fertility and water management. Farmers' infrequent use of inputs to control them was caused by various factors, ranging from fears of undesired side effects (agronomic) to a lack of quality control of products (institutional). Furthermore, there may be enough extension agents, but they lack the required training on (parasitic) weed management to provide farmers with advice, while their organizations do not provide them with the necessary means for farm visits. At even higher organizational levels we observed a lack of coherent policies on parasitic weed control and implementation of them. Merits and challenges of an integrated multi-stakeholder and multi-level research project are discussed
On the Consistency of Dynamic Wetting Boundary Conditions for the Navier-Stokes-Cahn-Hilliard Equations
We investigate the limiting behavior of the Navier-Stokes-Cahn-Hilliard model for binary-fluid flows as the diffuse-interface thickness passes to zero, in the presence of fluid-fluid-solid contact lines. Allowing for motion of such contact lines relative to the solid substrate is required to adequately model multi-phase and multi-species fluid transport past and through solid media. Even though diffuse-interface models provide an inherent slip mechanism through the mobility-induced diffusion, this slip vanishes as the interface thickness and mobility parameter tend to zero in the so-called sharp-interface limit. The objective of this work is to present dynamic wetting and generalized Navier boundary conditions for diffuse-interface models that are consistent in the sharp-interface limit. We concentrate our analysis on the prototypical binary-fluid Couette-flow problems. To verify the consistency of the diffuse-interface model in the limit of vanishing interface thickness, we provide reference limit solutions of a corresponding sharp-interface model. For parameter values both at and away from the critical viscosity ratio, we present and compare the results of both the diffuse- and sharp-interface models. The close match between both model results indicates that the considered test case lends itself well as a benchmark for further research
New media and the circuit of cyber-culture: Conceptualizing Napster
Media studies scholars have employed the cultural circuit model to analyze media in the context of capitalist political economy. This model identifies interrelated moments\u27 in which the meanings of cultural products are determined, negotiated, and subverted in interaction between producers and audiences. The turbulent evolution of new media, however, requires continuous reflection on the adequacy of conceptual tools. Analysis of recent controversy surrounding the Internet music-exchange service Napster indicates that the cultural circuit model must be modified to accommodate the emerging media of cyber-culture
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