TaskGenX: A Hardware-Software Proposal for Accelerating Task Parallelism

As chip multi-processors (CMPs) are becoming more and more complex, software solutions such as parallel programming models are attracting a lot of attention. Task-based parallel programming models offer an appealing approach to utilize complex CMPs. However, the increasing number of cores on modern CMPs is pushing research towards the use of fine grained parallelism. Task-based programming models need to be able to handle such workloads and offer performance and scalability. Using specialized hardware for boosting performance of task-based programming models is a common practice in the research community. Our paper makes the observation that task creation becomes a bottleneck when we execute fine grained parallel applications with many task-based programming models. As the number of cores increases the time spent generating the tasks of the application is becoming more critical to the entire execution. To overcome this issue, we propose TaskGenX. TaskGenX offers a solution for minimizing task creation overheads and relies both on the runtime system and a dedicated hardware. On the runtime system side, TaskGenX decouples the task creation from the other runtime activities. It then transfers this part of the runtime to a specialized hardware. We draw the requirements for this hardware in order to boost execution of highly parallel applications. From our evaluation using 11 parallel workloads on both symmetric and asymmetric multicore systems, we obtain performance improvements up to 15×, averaging to 3.1× over the baseline.This work has been supported by the RoMoL ERC Advanced Grant (GA 321253), by the European HiPEAC Network of Excellence, by the Spanish Ministry of Science and Innovation (contracts TIN2015-65316-P), by the Generalitat de Catalunya (contracts 2014-SGR-1051 and 2014-SGR-1272), and by the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 671697 and No. 779877. M. Moretó has been partially supported by the Ministry of Economy and Competitiveness under Ramon y Cajal fellowship number RYC-2016-21104. Finally, the authors would like to thank Thomas Grass for his valuable help with the simulator.Peer ReviewedPostprint (author's final draft

In His Own Words: Houston Hartsfield Holloway\\u27s Slavery, Emancipation, And Ministry In Georgia

The Life and Times of Houston Holloway Recovered This work adds another important volume to the corpus of historical literature that offer first-hand accounts of African Americans both during and after slavery in the American South. With the meticulous research and editorial care of David E. Pate...

Proteomic variations between a Mycoplasma gallisepticum vaccine strain and a virulent field isolate

Mollicutes (mycoplasmas) are pathogenic in a wide range of mammals (including humans), reptiles, fish, arthropods, and plants. Of the medically important mollicutes, Mycoplasma gallisepticum is of particular relevance to avian agriculture and veterinary science, causing chronic respiratory disease in poultry and turkey. Using two-dimensional electrophoresis based quantitative expression proteomics, the current study investigated the molecular mechanisms behind the phenotypic variability between a M. gallisepticum vaccine strain (6/85) and a competitive, virulent field strain (K5234), two strains which were indistinguishable using commonly accepted genetic methods of identification. Twenty-nine proteins showed a significant variation in abundance (fold change \u3e 1.5, p-value \u3c 0.01). Among others, the levels of putative virulence determinants were increased in the virulent K5234, while the levels of several proteins involved with pyruvate metabolism were decreased. It is hoped that the data generated will further the understanding of M. gallisepticum virulence determinants and mechanisms of infection, and that this may contribute to the optimization of diagnostic methodologies and control strategies

Scaling analysis of electron transport through metal-semiconducting carbon nanotube interfaces: Evolution from the molecular limit to the bulk limit

We present a scaling analysis of electronic and transport properties of metal-semiconducting carbon nanotube interfaces as a function of the nanotube length within the coherent transport regime, which takes fully into account atomic-scale electronic structure and three-dimensional electrostatics of the metal-nanotube interface using a real-space Green's function based self-consistent tight-binding theory. As the first example, we examine devices formed by attaching finite-size single-wall carbon nanotubes (SWNT) to both high- and low- work function metallic electrodes through the dangling bonds at the end. We analyze the nature of Schottky barrier formation at the metal-nanotube interface by examining the electrostatics, the band lineup and the conductance of the metal-SWNT molecule-metal junction as a function of the SWNT molecule length and metal-SWNT coupling strength. We show that the confined cylindrical geometry and the atomistic nature of electronic processes across the metal-SWNT interface leads to a different physical picture of band alignment from that of the planar metal-semiconductor interface. We analyze the temperature and length dependence of the conductance of the SWNT junctions, which shows a transition from tunneling- to thermal activation-dominated transport with increasing nanotube length. The temperature dependence of the conductance is much weaker than that of the planar metal-semiconductor interface due to the finite number of conduction channels within the SWNT junctions. We find that the current-voltage characteristics of the metal-SWNT molecule-metal junctions are sensitive to models of the potential response to the applied source/drain bias voltages.Comment: Minor revision to appear in Phys. Rev. B. Color figures available in the online PRB version or upon request to: [email protected]

Is Apremilast 30mg Effective in Lowering DLGI Scores in Patients with Plaque Psoriasis in 16 Weeks of Therapy?

Objective: The objective of this selective EBM review is to determine whether or not “Is Apremilast 30 mg effective in lowering DLQI scores in patients with plaque psoriasis in 16 weeks of therapy?” Study Design: Review of three randomized, blind, placebo-controlled clinical trials published between the years 2013 and 2016. Data Sources: All studies were published in peer-reviewed journals that were located using PubMed database searches. Outcome Measured: The DLQI is a 10-item questionnaire that assesses the impact of skin disease on health-related quality of life (HRQOL) over the previous week. Scores for each item range from 0 (not at all affected) to 3 (very much affected); total scores range from 0 to 30 and those \u3e10 represent a very large impact on HRQOL. Patients answered questions regarding their physical discomfort and limitations in activities of daily living to psychosocial problems and emotional distress caused by the condition. Results: All studies showed a statistical significance when comparing Apremilast 30mg BID to a placebo therapy. DLQI scores were decreased by 6.7 points in the study performed by Paul et al., 8.3 points with Reich et al. data, and lastly 4.4 points with the Strand et al. study. (P- values for all studies \u3c0.05) Conclusion: According to this EBM review Apremilast 30mg is effective in lowering DLQI scores in patients with plaque psoriasis in 16 weeks of therapy. Some studies showed more significant decreases in DLQI scores but overall a patient would experience a lower impact of skin disease on health-related quality of life

Prospectus, October 3, 1972

ELECTIONS; Journalism Club; Veteran\u27s Van; Cheerleading Tryouts; Literary Magazine; Pre-Registration; Cruisin\u27 \u2772; Prospectus Information; An Interview With Robbie Walker, Dan Walker\u27s Daughter; No Babies - Maybe; Vet Info; Scholarship; Gripes Gripes Gripes; New Concept Scouting; Afro-American History for Whom?; Parking at Parkland; Parkland College Student Association Budget For The Fiscal Year July 1, 1972, to June 30, 1972; Roosevelt U. Counseling; Radio Dinnerhttps://spark.parkland.edu/prospectus_1972/1005/thumbnail.jp

Theoretical Principles of Single-Molecule Electronics: A Chemical and Mesoscopic View

Exploring the use of individual molecules as active components in electronic devices has been at the forefront of nanoelectronics research in recent years. Compared to semiconductor microelectronics, modeling transport in single-molecule devices is much more difficult due to the necessity of including the effects of the device electronic structure and the interface to the external contacts at the microscopic level. Theoretical formulation of the problem therefore requires integrating the knowledge base in surface science, electronic structure theory, quantum transport and device modeling into a single unified framework starting from the first-principles. In this paper, we introduce the theoretical framework for modeling single-molecule electronics and present a simple conceptual picture for interpreting the results of numerical computation. We model the device using a self-consistent matrix Green's function method that combines Non-Equilibrium Green's function theory of quantum transport with atomic-scale description of the device electronic structure. We view the single-molecule device as "heterostructures" composed of chemically well-defined atomic groups, and analyze the device characteristics in terms of the charge and potential response of these atomic groups to perturbation induced by the metal-molecule coupling and the applied bias voltage. We demonstrate the power of this approach using as examples devices formed by attaching benzene-based molecules of different size and internal structure to the gold electrodes through sulfur end atoms.Comment: To appear in International Journal of Quantum Chemistry, Special Issue in memory of J.A. Pople. 13 pages, 9 figure