Review on Android Application – An E-Notice Application

E-Notice App helps you access on-line notices on your phone. It is a web board maker, wherever, a gaggle of individuals will simply communicate with one another by protruding virtual notes. These notes will have text, images. The board has perpetually been the place wherever staff/students gathers to urge their latest unharness of company news. E-Notice brings the board to a virtual location wherever staff/students cannot solely browse notices, however, in real time react and answer them-from their own desks! With this electronic notice and announcement system, notification could also be sent out notifying workers that a brand new notice has been denote, wherever, workers might apprehend if it issues him directly. During this approach, E-Notice Application additionally is a listing for all workers within the directory. This eliminates the requirement to stay a separate listing that is tough to keep up thanks to the speedy movement of workers

Prevention of β-amyloid-induced toxicity in a differentiated neuronal (IMR32) cell line by Khaya grandifololia (Welw) C. DC.

Alzheimer’s disease (AD) belongs to the class of neurodegenerative disorder and is biochemically characterized by amyloid-β (Aβ) plaques deposition, accumulation of neurofibrillary tangles (NFTs) accumulation and ultimately neuronal loss. Even though, the progress made in developing efficient AD therapy, there is no effective drug capable to stop and/or slow down AD progression. In the current article, we investigated the neuroprotective effect of Khaya grandifololia crude extract and fraction 2 against Aβ42-induced cytotoxicity and hyperphosphorylation of tau protein in differentiated neuronal cells (IMR32). Reactive oxygen species production, apoptosis and mitochondrial dynamics and function, synaptic protein, and tau phosphorylation were evaluated using fluorescence microscopy and immunoblotting. Cell viability was assessed using the MTT assay. Findings revealed that exposure of differentiated IMR32 cells to Aβ42 alone induced the impairment of mitochondrial dynamics, decrease synaptic protein expression and increase hyperphosphorylation of tau protein (phospho tau181). In contrast, the presence of crude extract and KGf2 significantly inhibited the cleavage of Caspase-3 activation. In addition, the levels of synaptic proteins (Symptosomal associated protein 25 and Synaptosin) and superoxide dismutase were restored upon treatment with crude extract and fraction 2. Hyperphosphorylation of tau protein (Thr181) and ERK (Thr202/Tyr205) activities were also significantly reduced after treatment with crude extract and fraction 2. Our findings suggest that KG extract is a potential source for candidate drug against AD and may contribute to the development of efficient therapeutic strategy against AD

Unpacking overuse of androgen deprivation therapy for prostate cancer to inform de-implementation strategies

Peer reviewe

EFFECT OF MATRIX RHYTHM THERAPY ON A CHRONIC CASE OF MEDIAN NERVE ENTRAPMENT AT THE ELBOW JOINT

Pronator teres syndrome is a rare condition, in which compression on the median nerve occurs at the elbow joint. It is a very rare condition compare to carpel tunnel syndrome. Compression can cause pain and numbness in the hand. The most common cause of pronator teres syndrome is compression of the median nerve in between the two belley’s of pronator teres muscles. In the case of advanced disease, the pain and numbness can be managed by prednisolone injections. Some of the literature shows massage therapy also works on relieving the symptoms. Matrix rhythm therapy (MaRhyThe) has shown to be beneficial in the treatment of pain and movement disturbances. Matrix rhythm therapy is invented by Dr.Randoll from Germany for the treatment of pain and does not have side effects. The case report was aimed to evaluate the effect of matrix rhythm therapy on pronator teres syndrome which lasted for 60 minutes each day for 3 days and was divided into 3 zones along with other physiotherapy interventions. It showed a positive result in pronator teres syndrome as the pain was reduced on the 3rd day of the session.</jats:p

La(III), Pr(III), Gd(III), Tb(III) & Dy(III) Complexes of Aryl Furyl & Aryl Thienyl β-Diketones

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