STUDY OF THE EFFECT OF OBESITY ON IMMUNE CELLS ACTIVITY AND CARDIOVASCULAR DISEASE RISK IN EL-OUED (ALGERIA) WOMEN

Objective: This study was conducted to find out the effect of obesity on immune cells activity and some biochemical markers in women. Methods: The experimentation is carried out on 30 voluntary individuals were divided into two groups; 15 women with obesity (Body Mass Index [BMI]>30) were selected, On the other hand, we took 15 witnesses (BMI<30). All the volunteers were subjected to estimate the lipid profile, biochemical, and hematological parameters. Results: Results obtained show that there was a significant increase of blood glucose (p<0.05), triglyceride (p<0.05) and uric acid (p<0.001) and no significant change of other biochemical markers in obese people’s group when compared to the control subjects. In addition, the hematological results demonstrated that there was a significant decrease (p<0.05) of lymphocytes, hemoglobin, hematocrit, and mean corpuscular volume levels (p<0.01) in women with obesity compared to the controls. Conclusion: Our study reveals that the obesity may be induce the sever alteration in lipid profile which cause the cardiovascular risk for this population. In addition, the obesity causes a remarkable change in some biochemical markers and blood constituent’s anemia or other metabolic disorder in the body

Identification and assessment of Modifiable and Non-Modifiable risk factors and oxidative stress in pathophysiology of stroke diseases- a review

The aim of this review is the identifying the main factors risk factors and manifesting the role of oxidative stress as factors associated with stroke diseases. It is very difficult to determine the cause of stroke but studies scientists have shown that some characteristics and non-modifiable factors of peoples played a major role in developing strokelike, age, Gender, Race and Heredity. Other modifiable risk factors includehypertension, Heart disease, Diabetes mellitus, Dyslipidemia and Obesity have also been associated with higher stroke incidence. On the other hand, studies support that oxidative stress is directly involved in the genesis and aggressiveness appearance of stroke. However, cerebral dysfunction like Ischaemia would be followed by reperfusion leads to increased production of free radicals which induce also oxidative stress. In conclusion, changing human behavior in life is the first way to prevent stroke disease; on the other hand, we suggest that antioxidants treatment has great benefits in improving patient health and decreasing the vascular complications of stroke

Effect of the progressive substitution of metakaolinite by metallurgical residues on the properties of phosphate cementitious materials

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Characterization and acute toxicity evaluation of the MgO Nanoparticles Synthesized from Aqueous Leaf Extract of Ocimum basilicum L

The aim of this study was to prepare magnesium oxide nanoparticles (MgONPs) using aqueous leave extract of Ocimum basilicum L. and to evaluate their acute toxicity. The characteristics of biosynthesized MgO powder was analyzed by UV–Vis spectroscopy, scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR). The acute toxicity test of MgONPs was applied in Wistar albino rats with different concentration. Results showed that the broad bell-shaped spectrum band was obtained by UV–Vis spectroscopy indicates the formation of MgO. The SEM images provided further insight into the shape and size of MgO which to be ranging under 440 nm. Fourier transform infrared (FTIR) spectroscopy detected the vibration of the Mg─O bond that indicate the presence of magnesium oxide nanoparticles (MgO). In this study, the toxicity test showed no mortality or behavioral change in low dose of MgNPs (250 mg / kg b.w) but we observed that 50% of rats have died when treated with high dose of MgNPs (500 mg/kg b.w.). This study confirmed that aqueous extract of Ocimum basilicum L. has potential properties as biocatalyst for the biosynthesis of MgONPs without any toxicity under dose 250 mg/kg in rats.</jats:p

Zinc Supplementation Prevents the Complications of COVID-19 Infection in Cancer Patients

Novel coronavirus” SARS-CoV-2 is rapidly spreading worldwide with a significant mortality rate. In the crisis of COVID-19, cancer patients are seen as a very weak group and this is because of their weakened immune system and hence we aim in this research to show the importance of zinc as a buffer against cancer in COVID-19 for cancer patients. Zinc is an essential trace element that is crucial for growth, development, and the maintenance of immune function. zinc supplementation decreased and generation of inflammatory cytokines. zinc supplementation should have beneficial effects on cancer by decreasing oxidative stress, angiogenesis and induction of inflammatory cytokines while increasing apoptosis in cancer cells. zinc supplementation implemented to improve the antiviral response and systemic immunity in patients with cancer diseases. With the multiple doses approved from zinc, we suggest that there be an supplement in zinc by 50 mg / day for three month with each treatment for cancer patients, in order to strengthen the immune system to prevent the serious effects of COVID19 infection.</jats:p

Prevalence and Epidemiological Study of hepatitis B and C patients admitted to BEN AMOR DJILANI hospital in El Oued, Algeria

The Goal of the present study is to evaluate the epidemiological variations of hepatitis B and C in El Oued population. Our epidemiological study was carried out on 1798 hepatitis patients admitted to hospital BEN AMOR DJILANI the period (January 2013 to December 2020) in El Oued region. In Results, 5.45% of patients were aged less than 20 years 72.14% of the patients are aged between 20-40 years, 15.85% patients are ages between 40-60 years and 6.56 % patient are aged more than 60 years. In the other hand, 57.29% of hepatitis patients are men versus 42.71% are women. In this study, 95% of the patients had a hepatitis B whereas 5% of the people were affected by hepatitis C. Concerning regions of hepatitis patients, the eastern region include the highest number with 37%, followed by - with a small difference - the central region with 33%, then come the southern region with 18%, the northern region contain 11% and at least the western region which include the lowest number of hepatitis patients with 1%, of total cases of hepatitis patients in the state of El Oued. Hence epidemiological studies are needed to understand and improve facilities and implement effective treatment measures to control the disease and thus help to reduce mortality in the society associated with this disease.</jats:p