The Education of the Accelerated Child

Nature has bestowed upon some of its children a gift so mysterious in its operations, so wonderful in its products and so tremendous in its influence that it baffles the most cultured and powerful minds in the attempt to analyze its workings. Even the possessor is unable to trace either -its origin or its mode of action. It is the common parent of invention and science of music and poetry and its chief distinction lies in the ability to penetrate farther into the field of truth than ordinary minds can do. To live in worlds that are unknown except to those divinely gifted, in other words possessing that peculiar quality of mind known as Genius. So subtle and impalpable is this faculty that although we are aware of its presence and can easily recognize it when it manifests itself yet we cannot tell exactly in what it consists. First, because no one unpossessed of creative imagination can study its operations within himself, while second, those who do possess this quality are seldom given to self analysis

Integrated People and Freight Transportation:A Literature Review

Increasing environmental and economic pressures have led to numerous innovations in the logistics sector, including integrated people and freight transport (IPFT). Despite growing attention from practitioners and researchers, IPFT lacks extensive research coverage. This study aims to bridge this gap by presenting a general framework and making several key contributions. It identifies, researches, and explains relevant terminologies, such as cargo hitching, freight on transit (FoT), urban co-modality, crowd-shipping (CS), occasional drivers (OD), crowdsourced delivery among friends, and share-a-ride, illustrating the interaction of IPFT with different systems like the sharing economy and co-modality. Furthermore, it classifies IPFT-related studies at strategic, tactical, and operational decision levels, detailing those that address uncertainty. The study also analyzes the opportunities and challenges associated with IPFT, highlighting social, economic, and environmental benefits and examining challenges from a PESTEL (political, economic, social, technological, environmental, and legal) perspective. Additionally, it discusses practical applications of IPFT and offers recommendations for future research and development, aiming to guide practitioners and researchers in addressing existing challenges and leveraging opportunities. This comprehensive framework aims to significantly advance the understanding and implementation of IPFT in the logistics sector

How Physicians Draw Satisfaction and Overcome Barriers in their Practices: “It Sustains Me”

Objective Major reorganizations of medical practice today challenge physicians’ ability to deliver compassionate care. We sought to understand how physicians who completed an intensive faculty development program in medical humanism sustain their humanistic practices. Methods Program completers from 8 U.S. medical schools wrote reflections in answer to two open-ended questions addressing their personal motivations and the barriers that impeded their humanistic practice and teaching. Reflections were qualitatively analyzed using the constant comparative method. Results Sixty-eight physicians (74% response rate) submitted reflections. Motivating factors included: 1) identification with humanistic values; 2) providing care that they or their family would want; 3) connecting to patients; 4) passing on values through role modelling; 5) being in the moment. Inhibiting factors included: 1) time, 2) stress, 3) culture, and 4) episodic burnout. Conclusions Determination to live by one’s values, embedded within a strong professional identity, allowed study participants to alleviate, but not resolve, the barriers. Collaborative action to address organizational impediments was endorsed but found to be lacking. Practice implications Fostering fully mature professional development among physicians will require new skills and opportunities that reinforce time-honored values while simultaneously partnering with others to nurture, sustain and improve patient care by addressing system issues

The cover

''Örtü'' filmi, terk edilme olgusunu işleyen kısa bir filmdir. Film, terk edilmenin yarattığı sarsıntıyı, yalnızlığı ve ruhsal yıkımı yansıtır. Filmdeki ikinci anlam katmanı mekânın anlatısallığından yararlanarak oluşur. Hikâye, bodrumu ve çatı katı bulunan bir evde geçer. Filmin içeriği ve mekânın niteliği, psikanalizin id, ego ve süperego kavramlarına göndermeler yapacak şekildedir. Bilinç ve bilinçaltının oluşumu, insanın insanla ve nesneyle kurduğu etkileşim önemli bir sorundur. Psikanaliz ve diyalektik materyalizmin bu konulara yaklaşımı farklıdır. Film, evli bir çiftin arasındaki çatışmalı ilişkiyi, insan bilincinin ve ilişkilerinin, toplumsal yapı içinde ve tarihsel süreçte oluştuğu gerçeği temelinde ele almıştır. Filmin anlatısı rüya üzerine kurulduğu için, rüya estetiğinin bütün boyutları da diyalektik bakış açısıyla ortaya konmuştur.The film as known "Örtü" is a short film focusing on dereliction phenomenon. The film reflects shake, loneliness and mental destruction all of which are caused by dereliction. The second layer of meaning in the movie is formed by benefiting from the narrative of the place. The story takes place at a house that has a basement and penthouse. The content of the movie and the quality of the place have a form to make cross-references to the id, ego and superego concepts of psychoanalysis. The formation of conscious and subconscious, the interaction that humans establish with humans and objects are important problems. Psychoanalysis and dialectical materialism have different approaches to these matters. The movie was taken the conflicting relationship between the married couple at the bottom of the real that human consciousness and relations are formed in the social structure and historical process. Since the narration of the film was established on dream, all dimensions of the dream esthetics were also set forth from a dialectical perspective

Funding Collaboratives for Neighborhood Organizations: An Analysis of Local and National Experiences.

Conducted on behalf of The Minneapolis Center for Neighborhoods. Sponsored by Neighborhood Planning for Community Revitalization, Center for Urban and Regional Affairs, University of Minnesota

Change detection in Southern Turkey using normalized difference vegetation index (NDVI)

This study analyzed landscape changes in the Mediterranean using remotely sensed satellite images. Bitemporal Thematic Mapper (TM) scenes of Erdemli (Southern Turkey) acquired by Landsat satellites were analyzed to detect landscape changes in the study area, which supports a mosaic of landscapes from coastline to altitudes over tree line. Visible and near infrared bands (i.e. bands 3 and 4) of the near-anniversary (August) images from 1984 and 2006 were used to derive Normalized Difference Vegetation Index (NDVI) images. NDVI images for the earlier and later dates were analyzed. ASTER and Quickbird images, topographic maps, forest stand maps were used as ancillary data. Spatial distribution of change is mapped and interpreted. Results showed that forest regeneration took place especially in upper lands, while deforestation occurred at lower altitudes in relatively smaller patches in close proximity to the coast and to the roads. First published online: 14 Dec 201

Characterization of the DNA polymerases induced by a group of herpes simplex virus type I variants selected for growth in the presence of phosphonoformic acid

Five independently derived variants of a herpes simplex virus type I (HSV-1) strain were plaque purified from a virus population passaged in 1 mM phosphonoformic acid (PFA). The DNA polymerase induced by the parent and PFA-resistant viruses were purified and characterized. No differences were observed among the enzymes with respect to their chromatographic properties, specific activities, or polypeptides resolved by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. The variant enzymes exhibited levels of PFA resistance which ranged from 15- to 25-fold. Resistance to PFA was always associated with a similar degree of resistance to its congener phosphonoacetic acid, but cross-resistance to beta-phenylphosphonoacetic acid was only seen with two of the five variant enzymes. PFA and pyrophosphate were mutually competitive in PPi exchange reactions, but in DNA synthetic reactions the levels of resistance to PFA and PPi were not equal. The apparent affinities of the enzymes for Mg2+ did parallel their affinities for PFA. Km values of dNTPs were about 2-fold higher than the parent virus enzyme for all of the variant enzymes except one which was 4-fold higher. The processivity of polymerization was apparently unaffected by the enzyme changes related to PFA resistance although one variant enzyme had a lower value. Resistance among the variant enzymes to the triphosphates of 9-(2-hydroxyethoxymethyl)guanine and 2',3'-dideoxyguanosine was directly related to the level of resistance to PFA. The data presented here indicated that (i) PFA resistance may result from several types of active site alterations, since the PFA-resistant enzymes were of three kinetically distinct types. Also, additional enzyme alterations, probably unrelated to PFA resistance, were detected in one enzyme. (ii) PFA and PPi possess some different binding determinants within the active center of herpes simplex virus type I DNA polymerase. (iii) PFA and the triphosphates of 9-(2-hydroxyethoxymethyl)guanine and 2',3'-dideoxyguanosine may have a common ultimate inhibitory mechanism