672 research outputs found
Sounding the Alarm on Inflation Indexing and Strict Inflation Targeting
Unanticipated inflation or deflation causes one party of a nominal contract to gain at the expense of the other party, an effect absent in macroeconomic models with one representative consumer or with consumers having identical consumption. In this paper's general dynamic and stochastic equilibrium model, diverse consumers maximize risk-averse utility and rent labor and land to profit-maximizing firms. Both inflation indexing and strict inflation targeting are Pareto inefficient. When Pareto sharing of changes of aggregate supply is proportional, nominal contracts under perfect nominal income targeting are Pareto efficient, while quasi-real contracts are Pareto efficient regardless.inflation indexing, inflation targeting, quasi-real indexing, nominal income targeting
Quasi-Real Indexing-- The Pareto-Efficient Solution to Inflation Indexing
In a pure-exchange economy with one good, stochastic aggregate demand and supply, and consumers having the same relative-risk aversion, Pareto efficiency requires each individual’s consumption to be proportional to aggregate supply. While neither nominal contracts nor pure inflation- indexed contracts provide this proportionality, quasi-real contracts do. Quasi-real contracts adjust for aggregate-demand-caused inflation but not for aggregate-supply-caused inflation, causing their real obligations to be proportional to aggregate supply. When consumers differ in their relative risk aversion, or experience stochastic utility or endowment shocks, they will need insurance and other risk-transfer contracts in addition to quasi-real contracts.inflation indexing, quasi-real indexing
Functional Properties and Oxidative Stability of Flaxseed Oil Microencapsulated by Spray Drying Using Legume Proteins in Combination with Soluble Fiber or Trehalose
Exploration of Health Care Needs Among Sudanese Refugee Women
Many Sudanese refugees that have resettled in the United States have experienced severe trauma and loss during their migration, as well as physical, social, and psychological struggles in their continued adaptation to living in a new country. This study explored the healthcare needs of Sudanese women as they transition to living in the United States. Community-Based Collaborative Action Research (CBCAR) provided a framework for the study.
Qualitative descriptive design using focus groups was utilized to explore the healthcare needs of Sudanese Women. Eighteen women participated in the study, which consisted of five educational sessions that were immediately followed by five audio-taped focus groups. The educational seminars presented topics such as parenting skills, preventative health practices, childhood illnesses, and emotional well-being. Focus groups allowed for a confidential setting in which women were able to reflect on the information presented, as well as verbalize topics that they would like to receive more education on in the future.
Three themes were identified that reflected experience of Sudanese women. These included being pulled between two worldviews in ways of parenting and communicating with children, multiple difficulties maneuvering within the US health care system, and internal struggles in meeting emotional needs in their transition to living in the United States. This study may contribute to the empowerment of Sudanese women by providing them with a greater understanding and ability to maneuver within the US healthcare system. This partnering interchange may also increase nursing knowledge in offering culturally competent care to the Sudanese community and other refugee populations that have resettled in the United States.University of Kansas School of Nursing. Bachelor of Science in Nursing Honors Progra
Altered cannabinoid receptor expression in pancreatic islets in experimental model of uraemia
Background: Uraemia leads to a number of metabolic and hormonal disorders including defective carbohydrate metabolism. Endocannabinoids exert their effect on insulin and glucagon secretion via activation of specific receptors named CB1 and CB2. For this reason and the absence of reports on location and immunoreactivity of CB1, CB2 receptors compared to immunoreactivity of insulin- and glucagon-secreting cells in experimental uraemia, the author decided to investigate this issue. The aim of the present study was the immunohistochemical localisation and evaluation of cannabinoid receptors (CB1, CB2), insulin and glucagon in the pancreatic islets of uraemic rats.
Materials and methods: Fragments of the rat’s pancreas were collected 28 days after surgical resection of one kidney and removal of 70% of the other kidney cortex. Paraffin-embedded sections were stained with haematoxylin-eosin and immunohistochemical reactions were performed with the use of a specific antibody against CB1-, CB2-receptors, insulin and glucagon.
Results: It was revealed the decreased immunoreactivity of the CB1 receptor and higher intensity of the immunohistochemical reaction against CB2 receptor as compared to the value in the control animals. Significantly higher immunoreactivity of glucagon-positive cells and weaker immunoreactivity of insulin-positive cells were observed in pancreatic islets of uraemic rats.
Conclusions: The obtained results indicate the involvement of cannabinoid receptors in the pathomechanism of carbohydrate metabolism disorders, associated with abnormal secretion of hormones by the α and β cells in uraemia
The Development and Subsequent Elimination of Aberrant Peripheral Axon Projections in Semaphorin3A Null Mutant Mice
AbstractSemaphorin3A (previously known as Semaphorin III, Semaphorin D, or collapsin-1) is a member of the semaphorin gene family, many of which have been shown to guide axons during nervous system development. Semaphorin3A has been demonstrated to be a diffusible chemorepulsive molecule for axons of selected neuronal populations in vitro. Analysis of embryogenesis in two independent lines of Semaphorin3A knockout mice support the hypothesis that this molecule is an important guidance signal for neurons of the peripheral nervous system (M. Taniguchi et al., 1997, Neuron 19, 519–530; E. Ulupinar et al., 1999, Mol. Cell. Neurosci. 13, 281–292). Surprisingly, newborn Semaphorin3A null mutant mice exhibit no significant abnormalities (O. Behar et al., 1996, Nature 383, 525–528). In this study we have tested the hypothesis that guidance abnormalities that occurred during early stages of Semaphorin3A null mice development are corrected later in development. We have found that the extensive abnormalities formed during early developmental stages in the peripheral nervous system are largely eliminated by embryonic day 15.5. We demonstrate further that at least in one distinct anatomical location these abnormalities are mainly the result of aberrant projections. In conclusion, these findings suggest the existence of correction mechanisms that eliminate most sensory axon pathfinding errors early in development
Macrofungi of the Bieszczady Mountains
The Bieszczady Mts, a mountain range in SE Poland, is a hot spot of fungal richness and diversity in Poland. This paper summarizes 5 years of studies in the Bieszczady Mts, as well as previously published research. A total of 1,377 macromycetes taxa were found, including many (464) which were protected, red-listed, or very rare in Poland. Thirty-eight taxa (nine Ascomycota and 29 Basidiomycota) have been reported in Poland for the first time: Agrocybe gibberosa, Auriporia aurulenta, Bolbitius variicolor, Bulgariella pulla, Chaetosphaerella phaeostroma, Clitocybe subspadicea, Clitopilus passeckerianus, Cortinarius anomalus var. subcaligatus, C. fervidus, C. flexipes var. inolens, C. sylvae-norvegicae, Cudoniella tenuispora, Entoloma bisporigerum, E. olorinum, E. poliopus var. parvisporigerum, E. sericeoides, Galerina caulocystidiata, Gymnopilus josserandii, Hymenoscyphus subferrugineus, Hypholoma olivaceotinctum, Inocybe queletii, Laccaria altaica, Lactarius romagnesii, L. rostratus, Mycena epipterygia var. atroviscosa, M. epipterygia var. candida, M. polygramma f. candida, Octavianina lutea, O. mutabilis, Pachyella violaceonigra, Panaeolus papilionaceus var. capitatocystis, Phaeocollybia jennyae, Psathyrella almerensis, Pyrenopeziza inornata, Scutellinia torrentis, Tricholoma basirubens, Tricholomopsis flammula, and Vibrissea decolorans. For all new taxa, short descriptions based on the collected material have been provided
DipM, a new factor required for peptidoglycan remodelling during cell division in Caulobacter crescentus
In bacteria, cytokinesis is dependent on lytic enzymes that facilitate remodelling of the cell wall during constriction. In this work, we identify a thus far uncharacterized periplasmic protein, DipM, that is required for cell division and polarity in Caulobacter crescentus. DipM is composed of four peptidoglycan binding (LysM) domains and a C-terminal lysostaphin-like (LytM) peptidase domain. It binds to isolated murein sacculi in vitro, and is recruited to the site of constriction through interaction with the cell division protein FtsN. Mutational analyses showed that the LysM domains are necessary and sufficient for localization of DipM, while its peptidase domain is essential for function. Consistent with a role in cell wall hydrolysis, DipM was found to interact with purified murein sacculi in vitro and to induce cell lysis upon overproduction. Its inactivation causes severe defects in outer membrane invagination, resulting in a significant delay between cytoplasmic compartmentalization and final separation of the daughter cells. Overall, these findings indicate that DipM is a periplasmic component of the C. crescentus divisome that facilitates remodelling of the peptidoglycan layer and, thus, coordinated constriction of the cell envelope during the division process
Peranan Guru Bungan Dalam Melaksanakan Ritual Ngayo
According to local residents, the Long Amo village, also known as Uma Kayan Long Amo is a Kayan village located in Belaga, Sarawak. Some of the residents of this village still practice the traditional customs of the Kayan community, the Bungan customs, which have now been adopted as a religion by its devotees. In the religious customs of Bungan, there is a ritual that has its own significance for the Kayan community, which is the Ngayo ritual. The specific implementation of this ritual shows its significancee and position within the Kayan community. This ritual is led by an individual called Guru Bungan. The Guru Bungan also plays an important role in every other Bungan religious ritual. This article aims to explain the role of Guru Bungan in performing Ngayo ritual. A fundamental study was designed using qualitative methods to obtain data of this study. Given the significant knowledge gap on this topic, interviews were selected as the main method for data collection. The informants interviewed are Guru Bungan and selected villagers who are experts in this ritual.The findings of this study indicates that Guru Bungan bears a high responsibility in the traditional customs of the Kayan community. Guru Bungan is one of the individuals who must be present in almost all the cycles of Ngayo ritual ceremonies. The function of Guru Bungan in the Ngayo ritual is as the leader of the ritual ceremony who gives numerous instructions and reminders to ensure that every equipment and requirement in performing the ritual is done correctly. In addition, Guru Bungan also acts as an intermediary for Bungan religious customs and its followers
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Fabrication development for high-level nuclear waste containers for the tuff repository; Phase 1 final report
This final report completes Phase 1 of an engineering study of potential manufacturing processes for the fabrication of containers for the long-term storage of nuclear waste. An extensive literature and industry review was conducted to identify and characterize various processes. A technical specification was prepared using the American Society of Mechanical Engineers Boiler & Pressure Vessel Code (ASME BPVC) to develop the requirements. A complex weighting and evaluation system was devised as a preliminary method to assess the processes. The system takes into account the likelihood and severity of each possible failure mechanism in service and the effects of various processes on the microstructural features. It is concluded that an integral, seamless lower unit of the container made by back extrusion has potential performance advantages but is also very high in cost. A welded construction offers lower cost and may be adequate for the application. Recommendations are made for the processes to be further evaluated in the next phase when mock-up trials will be conducted to address key concerns with various processes and materials before selecting a primary manufacturing process. 43 refs., 26 figs., 34 tabs
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