Fiber optic temperature sensor

An inexpensive, lightweight fiber optic micro-sensor that is suitable for applications which may require remote temperature sensing. The disclosed temperature sensor includes a phosphor material that, after receiving incident light stimulation, is adapted to emit phosphorescent radiation output signals, the amplitude decay rate and wavelength of which are functions of the sensed temperature

Neurophysiology

Contains research objectives and summary of research on sixteen research projects.National Institutes of Health (Grant 5 TO1 EY00090-03)National Institutes of Health (Grant 3 RO1 EY01149-03S1)Bell Laboratories (Grant)National Institutes of Health (Grant 5 RO1 NS12307-02)National Institutes of Health (Grant K04 NS00010

Neurophysiology

Contains research objectives and summary of research on seventeen research projects and reports on four research projects.National Institutes of Health (Grant 5 TOl EY00090-02)Bell Telephone Laboratories, Inc. (Grant)National Institutes of Health (Grant 5 ROI EY01149-03)National Institutes of Health (Grant NS 12307-01)National Institutes of Health (Grant 1 K04 NS00010

Continuous Measurements of Water Status in Deeply Rooted Southern California Chaparral Shrub Species

Much of Southern California experiences a Mediterranean climate, with long, hot summers and cool, wet winters. Characteristic plants include the deeply-rooted shrubs collectively known as chaparral. Such species, including Malosma laurina (Laurel Sumac, Family Anacardiaciae) and Heteromeles arbutifolia (Toyon, Family Rosaceae), have the ability to tap cool, deep waters. Chaparral species face severe drought stress during the summer, which can be quantified in measurements of water status. Measuring water status continuously in situ can prove challenging, partially because some instruments are extremely sensitive to the extreme temperature gradients experienced by chaparral shrubs during the summer, and often require complex protocols for installation and maintenance. This study was conducted to develop two methods, stem psychrometry and measuring air flow into xylem, for using plant water status sensors on deeply-rooted chaparral shrubs. It was found that temperature gradients in large basal stems caused by ascent of cool xylem sap from deep soil layers can lead stem psychrometers to report overly-negative water potential readings midday. Attempts to correct for these temperature effects turned out to be unsuccessful, leading to a recommendation to install psychrometers on smaller branches up high. Air flow into xylem occurs during embolism spread or repair, possibly as stable nanobubbles are pulled through pit membranes, driven by the pressure gradient between air and xylem sap, and subsequently dissolved into the iii xylem sap. Using a liquid flow gauge to measure air flow into xylem, one set of measurements out of many attempts was completed, demonstrating the validity of the approach.978133975307

Neurophysiology

Contains reports on twenty research projects.Bell Laboratories (Grant)National Institutes of Health (Grant 5 R01 EY01149-03S2)National Institutes of Health (Grant 5 TO1 EY00090-04)National Institutes of Health (Grant 5 RO1 NS12307-03)National Institutes of Health (Grant K04 NS00010)National Multiple Sclerosis Society (Grant RG-1133-A-1)Health Sciences Fund (Grant 78-10

Current Perspectives on Western Boreal Forest Life: Ethnographic and Ethnohistoric Research in Late Prehistoric and Historic Archaeology - A Preface

At the 1987 Society for American Archaeology Meetings in Toronto, several scholars gathered to present their most recent research using ethnographic and ethnohistoric information to study late prehistoric and historic Athabaskan archaeology in the western subarctic interior. ... The papers from this symposium make up the rest of this volume; this preface provides the reader with some background for better appreciating the papers that follow. The preface begins with a short historical summary of recent Athabaskan archaeology, including the use of ethnohistoric and ethnographic approaches. It continues with very brief summaries of the six papers as context for the subsequent comments, presented at the session by the symposium's two discussants, Polly McW. Quick and Donald W. Clark. Their comments touch on several important issues, including adaptation to environmental variability, the importance of explicit linkages between ethnographic information and archaeology, the value of oral history, the difficulties of projecting findings from recent historic sites back even to more distant historic sites, the promise and problems of interpreting social groupings from structural remains, the value of having northern researchers who live and work throughout the year in the North, and the need for better frameworks for linking ethnographic and ethnohistoric information with archaeology to permit some generalization. The preface closes with a discussion of future research directions and priorities. ...Key words: Alaska, archaeology, Athabaskans, boreal forest, Canada, ethnoarchaeology, ethnography, ethnology, ethnohistory, historic period, research priorities, Subarctic, symposiumMots clés: Alaska, archéologie, Athabaskans, forêt boréale, Canada, ethnoarchéologie, ethnographie, ethnologie, ethnohistoire, période historique, priorité dans la recherche, subarctique, symposiu

Pixantrone-rituximab versus gemcitabine-rituximab in relapsed/refractory aggressive non-Hodgkin lymphoma.

UNLABELLED: We describe the rationale and design of the ongoing randomized, active-controlled, multicenter, Phase III study evaluating the efficacy of pixantrone and rituximab versus gemcitabine and rituximab in patients with diffuse large B-cell lymphoma or follicular grade 3 lymphoma, who are ineligible for high-dose chemotherapy and stem cell transplantation, and who failed front-line regimens containing rituximab. The administration schedule is pixantrone 50 mg/m(2) intravenously (iv.) or gemcitabine 1000 mg/m(2) iv. on days 1, 8 and 15, combined with rituximab 375 mg/m(2) iv. on day 1, up to six cycles. Pixantrone has a conditional European marketing approval for monotherapy in adults with multiple relapsed or refractory aggressive B-cell non-Hodgkin lymphoma. Our trial explores the efficacy of combining pixantrone with rituximab and completes postauthorization measures. TRIAL REGISTRATION NUMBER: NCT01321541

Screening for Popliteal Aneurysms Should not be a Routine Part of a Community-Based Aneurysm Screening Program

Martin Claridge1, Simon Hobbs1, Clive Quick2, Donald Adam1, Andrew Bradbury1, Teun Wilmink11University Department of Vascular Surgery, Birmingham Heartlands Hospital, Birmingham, UK; 2Department of Surgery, Hinchingbrooke Hospital, Huntingdon, UKIntroduction: Several studies have found an increased incidence of peripheral aneurysms in patients with an abdominal aortic aneurysm (AAA). The aim of this study was to determine whether screening for popliteal aneurysms should be part of an AAA screening programme.Setting: A community-based AAA screening programmeMethods: The diameters of the internal abdominal aorta and both popliteal arteries were assessed by B-Mode ultrasound in a subgroup of the screened population. An AAA was defined as an infrarenal aortic diameter >29 mm. A popliteal aneurysm was defined as a popliteal diameter >19 mm.Results: Information was available for 283 subjects, 112 subjects with a small AAA, and 171 subjects with a normal aorta. No popliteal aneurysms were found in the subjects with a normal aorta. Three popliteal aneurysms were found in patients with a small AAA. Scanning both popliteal arteries took an experienced sonographer on average three times as long as scanning for an AAA (5 vs 15 minutes).Conclusion: Popliteal artery aneurysms are seen in less than 3% of men with a small AAA and not at all in men with a normal aortic diameter. It is therefore not cost effective to include screening for popliteal aneurysms in population screening for AAA.Keywords: popliteal aneurysm, screening progra

Sequential Complications of Hypercalcemia, Necrotizing Granulomatous Vasculitis, and Aplastic Anemia Occurring in One Patient with Angioimmunoblastic T-cell Lymphoma.

In this case report of a patient with angioimmunoblastic T-cell lymphoma (AITL), we describe the occurrence of three sequential complications that have been reported uncommonly in this disease subtype. Firstly, the patient developed hypercalcemia due to elevated 1,25-didydroxyvitamin D. Although hypercalcemia in AITL is not rare (1-2% incidence), this case was unusual in that the complication developed when disease appeared stable and symptomatically, he was doing well otherwise. Hypercalcemia surprisingly resolved a few months later at a time when his disease appeared to be progressing. A year later, the patient presented with digital ischemia necessitating partial amputation of a finger. Pathological exam revealed granulomatous vasculitis of small and medium arterioles with infiltrating malignant T lymphocytes. Although skin manifestations are common in AITL, necrotizing granulomatous vasculitis with accompanying tumor cells leading to severe digital ischemia appears rare. Subsequently the patient developed profound pancytopenia with bone marrow confirming severe aplastic anemia. To our knowledge only one other case of aplastic anemia has been reported in a patient with AITL. We discuss the diagnostic and management considerations involved in this patient care and review similar reported cases