77 research outputs found
Coronary artery aneurysm in Kawasaki disease.
A 3-year-old male presents to the emergency department with chief complaints of fever and vomiting. He had a positive rapid streptococcus throat test with cervical lymphadenopathy. The patient was started on antibiotics. On examination, there was diffuse erythematous macular rash on the chest. Laboratory tests revealed elevated white cell count and C-reactive protein. Electrocardiogram was notable for prolonged PR interval indicating 1st degree atrioventricular block. Echocardiogram revealed ectasia of the right coronary artery (RCA). A presumptive diagnosis of Kawasaki disease was made and the patient was started on high-dose aspirin and intravenous immunoglobulins. Cardiac computed tomography angiography (CTA) showed an aneurysm of the proximal RCA measuring up to 7.4 mm. The RCA immediately proximal to the aneurysm measured 3 mm in diameter. The Z score was 13.4. Oblique coronal image from cardiac CTA and volume rendered images demonstrated an aneurysm of the proximal RCA. The patient improved with treatment
Linear oligofluorene-BODIPY structures for fluorescence applications
A family of linear oligofluorene-BODIPY structures, containing either a ter- or quaterfluorene unit, have been prepared, in which the attachment of the oligofluorene chain to the BODIPY unit is switched between the meso-and beta-positions. Each member of this family was investigated by UV-vis absorption and photoluminescence spectroscopy, cyclic voltammetry and thermal studies (TGA and DSC) to determine their suitability as emissive layers in hybrid luminescent devices. One candidate was then successfully deployed as a down converter to convert UV to visible light
Treatment of Persistent Air Leaks using Endobronchial Valves
Introduction: Persistent air leaks (PAL) are from bronchopleural fistula resulting from communication between the bronchial tree and pleural space. Endobronchial valves (EBVs) are unidirectional valves placed bronchoscopically preventing airflow to the diseased lung lobe. For non-operable patients with PALs, EBVs offer a potential non-invasive treatment approach to stop air leak and allow lung healing. The purpose of this study is to retrospectively analyze EBV placement to treat non-operable adult patients with PALs.
Methods: We retrospectively analyzed all adult patients that underwent EBV placement for PAL treatment at our institution from January 2016 to June 2019. All patients failed conservative therapy with chest tubes before EBV placement. Descriptive statistics were used to analyze leak etiology, number of valves placed, duration of placement, and PAL resolution.
Results: A total of 20 EBV procedures occurred in patients with a median age of 63 (range = 38–79). Air leaks were spontaneous in 13 patients and either due to post-surgical or iatrogenic causes in 7 patients. By last follow-up, 60% of patients still retained all valves. Among patients that had valves removed, EBVs were in place for a median of 6 months (range = 2–21). 19 patients PALs resolved after EBV placement.
Discussion: Our data supports previous reports of the feasibility of successfully treating PALs using EBVs. Although this report requires validation in a larger cohort, our data suggests that compassionate exemption EBV placement can be a possible treatment alternative to current standard of care for patients with PALs that are non-operable
Smart helmet for safe driving
A smart helmet is a type of protective headgear used by the rider which makes bike driving safer than before. The main purpose of this helmet is to provide safety for the rider. This can be implemented by using advanced features like alcohol detection, accident identification, location tracking, use as a hands free device, fall detection. This makes it not only a smart helmet but also a feature of a smart bike. It is compulsory to wear the helmet, without which the ignition switch cannot turn ON. An RF Module can be used as wireless link for communication between transmitter and receiver. If the rider is drunk the ignition gets automatically locked, and sends a message to the registered number with his current location. In case of an accident it will send a message through GSM along with location with the help of GPS module. The distinctive utility of project is fall detection; if the rider falls down from the bike it sends a message
Gunshot-Related Pediatric Left Ventricular Apical Aneurysm
Penetrating injuries of the thorax and abdomen, such as gunshot and stabbing, are rare in children. We present the case of a pediatric patient with a history of remote gunshot injury presenting with a late aneurysm in the left ventricle
Boron difluoride formazanate copolymers with 9,9-di-n-hexylfluorene prepared by copper-catalyzed alkyne–azide cycloaddition chemistry
Synthesis of an E-BODIPY based fluorescent Co-polymer containing organoboron quinolate units
Uncommon Causes of Interlobular Septal Thickening on CT Images and Their Distinguishing Features
Interlobular septa thickening (ILST) is a common and easily recognized feature on computed tomography (CT) images in many lung disorders. ILST thickening can be smooth (most common), nodular, or irregular. Smooth ILST can be seen in pulmonary edema, pulmonary alveolar proteinosis, and lymphangitic spread of tumors. Nodular ILST can be seen in the lymphangitic spread of tumors, sarcoidosis, and silicosis. Irregular ILST is a finding suggestive of interstitial fibrosis, which is a common finding in fibrotic lung diseases, including sarcoidosis and usual interstitial pneumonia. Pulmonary edema and lymphangitic spread of tumors are the commonly encountered causes of ILST. It is important to narrow down the differential diagnosis as much as possible by assessing the appearance and distribution of ILST, as well as other pulmonary and extrapulmonary findings. This review will focus on the CT characterization of the secondary pulmonary lobule and ILST. Various uncommon causes of ILST will be discussed, including infections, interstitial pneumonia, depositional/infiltrative conditions, inhalational disorders, malignancies, congenital/inherited conditions, and iatrogenic causes. Awareness of the imaging appearance and various causes of ILST allows for a systematic approach, which is important for a timely diagnosis. This study highlights the importance of a structured approach to CT scan analysis that considers ILST characteristics, associated findings, and differential diagnostic considerations to facilitate accurate diagnoses
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