Summerlin Masonry

Summerlin Masonry is a residential masonry company located in the Bryan-College Station, Texas Metropolitan Statistical Area (MSA). The company specializes in rock, both real and fake, brick, glass block, and tile work. Summerlin Masonry mainly works on houses in upper-middle class neighborhoods, but occasionally works on commercial jobs as favors to builders. The company has performed very well in its first two years of operation. While the company has been performing very well, it has not been without problems. Due to deceptive practices of his former partner when he was with B&S Masonry, the owner has become indebted to the IRS. They are holding him responsible for the entire debt of payroll tax checks that were not deposited, plus penalties and interest. After many months of communication with the IRS, the owner has begun to lower his debt and fully intends to repay the entire debt for his partner’s mishap. In the past two years, Summerlin Masonry has doubled its business. Due to the high demand for the business’s services, expansion into new locations and markets are being considered. (Contact author for a copy of the complete report.)Small Business Mgmt, Ethics

Teorías y Sistemas Psicológicos - PS04 201601

El curso de Teorías y Sistemas Psicológicos es un curso de especialidad de la carrera de Psicología, de carácter teórico, dirigido a estudiantes de primer ciclo, que busca desarrollar la competencia general de pensamiento crítico y la competencia específica de fundamento teórico conceptual

The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

Renal cell carcinoma(RCC) is not a single disease, but several histologically defined cancers with different genetic drivers, clinical courses, and therapeutic responses. The current study evaluated 843 RCC from the three major histologic subtypes, including 488 clear cell RCC, 274 papillary RCC, and 81 chromophobe RCC. Comprehensive genomic and phenotypic analysis of the RCC subtypes reveals distinctive features of each subtype that provide the foundation for the development of subtype-specific therapeutic and management strategies for patients affected with these cancers. Somatic alteration of BAP1, PBRM1, and PTEN and altered metabolic pathways correlated with subtype-specific decreased survival, while CDKN2A alteration, increased DNA hypermethylation, and increases in the immune-related Th2 gene expression signature correlated with decreased survival within all major histologic subtypes. CIMP-RCC demonstrated an increased immune signature, and a uniform and distinct metabolic expression pattern identified a subset of metabolically divergent (MD) ChRCC that associated with extremely poor survival

Erratum: The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma (Cell Reports (2018) 23(1) (313–326.e5) (S2211124718304364) (10.1016/j.celrep.2018.03.075))

(Cell Reports 23, 313–326; April 3, 2018) In the originally published version of this article, the author list contained two errors. Specifically, David J. Kwiatkowski was misspelled as David J. Kwaitkowski, and William Y. Kim was inadvertently written as William T. Kim. Both names have been corrected online. The authors regret this error