Radio astronomy in Africa: the case of Ghana

South Africa has played a leading role in radio astronomy in Africa with the Hartebeesthoek Radio Astronomy Observatory (HartRAO). It continues to make strides with the current seven-dish MeerKAT precursor array (KAT-7), leading to the 64-dish MeerKAT and the giant Square Kilometer Array (SKA), which will be used for transformational radio astronomy research. Ghana, an African partner to the SKA, has been mentored by South Africa over the past six years and will soon emerge in the field of radio astronomy. The country will soon have a science-quality 32m dish converted from a redundant satellite communication antenna. Initially, it will be fitted with 5 GHz and 6.7 GHz receivers to be followed later by a 1.4 - 1.7 GHz receiver. The telescope is being designed for use as a single dish observatory and for participation in the developing African Very Long Baseline Interferometry (VLBI) Network (AVN) and the European VLBI Network. Ghana is earmarked to host a remote station during a possible SKA Phase 2. The location of the country on 5 degree north of the Equator gives it the distinct advantage of viewing the entire plane of the Milky Way galaxy and nearly the whole sky. In this article, we present the case of Ghana in the radio astronomy scene and the science/technology that will soon be carried out by engineers and astronomers.Comment: 6 pages, 3 figures, Full Referred Journal Article accepted for publication in the South African Institute of Physics (SAIP 2014) Conference Proceeding

Exploring Barrier-Free as a Catalyst to Smart Cities Initiatives in Sub Saharan Africa

The Sustainable Development Goals and the UN Conventions on the Rights of Persons with Disabilities both strive to make all cities and human settlements inclusive, safe and resilient without discrimination. Actions through policies, legislation and advocacy have been employed by Sub-Saharan Africa (SSA) governments to achieve barrier free environments with little progress. Smart community initiatives can become a potential conduit for speeding the development of barrier free environments in these countries. The study thus explores the concept of barrier free as a catalyst in smarting communities’ initiatives in Africa. An exploratory mixed methods approach is used through the review of epistemological assumptions of smart communities and surveys of perceptions of people from the university community. Case studies of selected smart city initiatives and smart university campuses were reviewed, and KNUST (as a microcosm of a city) with a population of 50,000 was used as a case study. The study revealed the silent nature of current smart city characteristics on barrier free features whilst technology and people remain the backbone of inclusive smart community initiatives. Again most respondents are optimistic of its success in SSA, though cautioning its cost. A low smart index score of 36.9 was recorded on the KNUST Campus. This study provides vital data to policy makers on implementation of integrated barrier free and smart community initiatives in Sub-Sahara Africa

Can a systems approach reduce adverse outcomes in patients with dementia in acute settings? (innovative practice)

People with dementia experience adverse outcomes such as pressure sores during their stay in acute hospitals. The application of a systems approach in an acute setting places an emphasis on the patient’s journey in addition to the organisational factors that are present within a hospital context. This article draws upon principles obtained from a theoretical model, which was extracted from the work of Edwards (1972), Hawkins (1987) and Zecevic et al. (2007), in order to illustrate how the application of a novel systems approach (human interaction, environment, equipment and policy) could be used in acute hospital settings to reduce adverse health outcomes by using an imaginary patient with dementia

Bayesian statistical inference of loglogistic model with interval-censored lifetime data

The properties of Palm Oil (PO) and Coconut Oil (CO) offer the potential for transformers Interval-censored data arise when a failure time say, T cannot be observed directly but can only be determined to lie in an interval obtained from a series of inspection times. The frequentist approach for analysing interval-censored data has been developed for some time now. It is very common due to unavailability of software in the field of biological, medical and reliability studies to simplify the interval censoring structure of the data into that of a more standard right censoring situation by imputing the midpoints of the censoring intervals. In this research paper, we apply the Bayesian approach by employing Lindley's 1980, and Tierney and Kadane 1986 numerical approximation procedures when the survival data under consideration are interval-censored. The Bayesian approach to interval-censored data has barely been discussed in literature. The essence of this study is to explore and promote the Bayesian methods when the survival data been analysed are is interval-censored. We have considered only a parametric approach by assuming that the survival data follow a loglogistic distribution model. We illustrate the proposed methods with two real data sets. A simulation study is also carried out to compare the performances of the methods

Differential Regulation of Cysteinyl Leukotriene Receptor Signaling by Protein Kinase C in Human Mast Cells

Cysteinyl leukotrienes (cys-LTs) are a group of lipid mediators that are potent bronchoconstrictors, powerful inducers of vascular leakage and potentiators of airway hyperresponsiveness. Cys-LTs play an essential role in asthma and are synthesized as well as activated in mast cells (MCs). Cys-LTs relay their effects mainly through two known GPCRs, CysLT1R and CysLT2R. Although protein kinase C (PKC) isoforms are implicated in the regulation of CysLT1R function, neither the role of PKCs in cys-LT-dependent MC inflammatory signaling nor the involvement of specific isoforms in MC function are known. Here, we show that PKC inhibition augmented LTD4 and LTE4-induced calcium influx through CysLT1R in MCs. In contrast, inhibition of PKCs suppressed c-fos expression as well MIP1β generation by cys-LTs. Interestingly, cys-LTs activated both PKCα and PKCε isoforms in MC. However, knockdown of PKCα augmented cys-LT mediated calcium flux, while knockdown of PKCε attenuated cys-LT induced c-fos expression and MIP1β generation. Taken together, these results demonstrate for the first time that cys-LT signaling downstream of CysLT1R in MCs is differentially regulated by two distinct PKCs which modulate inflammatory signals that have significant pathobiologic implications in allergic reactions and asthma pathology

Infection with Mansonella perstans Nematodes in Buruli Ulcer Patients, Ghana.

During August 2010-December 2012, we conducted a study of patients in Ghana who had Buruli ulcer, caused by Mycobacterium ulcerans, and found that 23% were co-infected with Mansonella perstans nematodes; 13% of controls also had M. perstans infection. M. perstans co-infection should be considered in the diagnosis and treatment of Buruli ulcer