Continuum simulations of shocks and patterns in vertically oscillated granular layers

We study interactions between shocks and standing-wave patterns in vertically oscillated layers of granular media using three-dimensional, time-dependent numerical solutions of continuum equations to Navier-Stokes order. We simulate a layer of grains atop a plate that oscillates sinusoidally in the direction of gravity. Standing waves form stripe patterns when the accelerational amplitude of the plate's oscillation exceeds a critical value. Shocks also form with each collision between the layer and the plate; we show that pressure gradients formed by these shocks cause the flow to reverse direction within the layer. This reversal leads to an oscillatory state of the pattern that is subharmonic with respect to the plate's oscillation. Finally, we study the relationship between shocks and patterns in layers oscillated at various frequencies and show that the pattern wavelength increases monotonically as the shock strength increases.Comment: 12 pages, 9 figure

Anticardiolipin antibodies and coronary heart disease

Arterial or venous thrombotic events have been described as complications in patients with positive anticardiolipin antibodies (aCL), affecting various organs including the heart. In order to see whether aCL could be, among others, a predisposing factor for coronary artery occlusions and whether it could serve as a prognostic marker for coronary heart disease, 232patients enrolled in the European Concerted Action on Thrombosis Angina Pectoris Study were studied. aCL and various other haemostatic parameters were determined at time of admittance in order to see whether a relationship existed between haemostasis at baseline and extent or prognosis of the cardiovascular disease. A follow-up at 12 and 24 months after angiography included information about relapsing coronary or other thrombotic events, treatment and outcome of the disease. aCL were not found to be a marker of either progressive cardiovascular disease or recurrent thrombotic events. No correlation was found, either in aCL positive or in aCL negative patients, between high levels of haemostasis activation markers, such as fi-thromboglobulin, platelet factor 4 or fibrinopeptide A and recurrent cardiovascular diseas

Thermomechanical and bithermal fatigue behavior of cast B1900 + Hf and wrought Haynes 188

High temperature thermomechanical and bithermal fatigue behavior was investigated for two superalloys: cast nickel-base B1900+Hf and wrought cobalt-base Haynes 188. Experimental results were generated to support development of an advanced thermal fatigue life prediction method. Strain controlled thermomechanical and load-controlled, strain-limited, bithermal fatigue tests were used to determine the fatigue crack initiation and cyclic stress-strain response characteristics of superalloys. Bithermal temperatures of 483 and 871 C were used for B1900+Hf, and 316 and 760 C for Haynes 188. Thermomechanical fatigue tests were conducted by using maximum and minimum temperatures corresponding to those for the bithermal experiments. Lives cover the range from about 10 to 3000 cycles to failure. Isothermal fatigue results obtained previously are also discussed

Stress test methodologies under scrutiny: examining the interplay of regulatory and market risk metrics in Europe – a comparative analysis of 2011 and 2021

This thesis replicates and extends the analysis from “Testing Macroprudential Stress Tests: The Risk of Regulatory Risk Weights” by Acharya, Engle, and Pierret (2014). It investigates the relationship between capital shortfall metrics and the effectiveness of risk factors in predicting stress-induced risks, using EBA stress tests from 2011 and 2021 alongside market-based metrics like SRISK. The findings validate critiques of risk-weighted measures, highlight the alignment of leverage-based and market-based metrics, and advocate for combining market-based and regulatory approaches. Additionally, the analysis suggests the successful implementation of regulatory standards, such as Basel III, and their impact on regulatory stress tests

The Environment of Education: Identifying Effects of the Hidden Curriculum on Students\u27 Environmental Perceptions, Values, and Attitudes

Our relationship with our environment is a function of culture and personal experience. Environmental perceptions, values, and attitudes are therefore linked to cultural standards. As Saul (2000) has stated, Environmental problems result from environmental practices, and environmental practices are cultural activities (p. 5). The link between environmental issues and cultural practices is clear, but the question of how to change cultural norms is a difficult one. Some environmental theorists claim the environmental movement has not paid enough attention to culture and has therefore failed to address problems at their true cause (Saul, 2000; Bowers, 1997)

Computer-Supported Hybrid Cooperative Work

This PhD examines the future of work after the COVID-19 pandemic, which introduced abrupt changes in work practices. The impact of long-term remote work extends beyond the lockdown periods and has reshaped work preferences, work-life balance, organizational management, and the integration of technologies that facilitate collaboration across distances. Situated within the field of computer-supported cooperative work (CSCW), this PhD researches contemporary work practices with a focus on what is important in designing cooperative technologies for hybrid work. Hybrid work is defined as cooperation involving both collocated and distributed individuals, supported by multiple physical and digital technologies. To uncover different perspectives of cooperative technologies for hybrid cooperative work, the research employs a mixed-method approach, integrating qualitative insights from literature and ethnographic studies, as well as quantitative data from a survey. This PhD thesis includes five research papers that, through different research lenses, provide distinct conceptualizations of hybrid work. The PhD examines: • The conceptualization and characterization of hybrid cooperative work • The spatial, infrastructural, and organizational challenges that hybrid work practices introduce• Design propositions for computing technologies supporting hybrid cooperative workThis PhD thesis brings together these findings and insights across the included research papers and proposes a framework of dimensional interdependencies in hybrid work. By conceptualizing the spectrum of cooperative work, the PhD thesis identifies unique characteristics of hybrid work, presents design propositions for technologies supporting hybrid practices, and addresses organizational complexities in managing contemporary work environments. The proposed framework unifies these perspectives, emphasizing the interdependent nature of cooperative work, the ecologies of technology artifacts supporting this work, the inherently multiple spatial contexts, and the organizational structuring – dimensions that should all be considered when designing computing technologies for hybrid cooperative work. Keywords: hybrid work, cooperative technology, mixed-method research, conceptual frameworks<br/

Prophylactic therapy with Fibrogammin ® P is associated with a decreased incidence of bleeding episodes: a retrospective study

Congenital factor XIII (FXIII) deficiency is an extremely rare, yet potentially life-threatening, bleeding disorder, with a 30% rate of spontaneous intracranial haemorrhage. Routine prophylactic management is recommended for all individuals with clinically relevant (FXIII) deficiency and for all symptomatic individuals with congenital factor deficiency. Fibrogammin ® P is a purified, pasteurized concentrate of FXIII that appears to carry negligible risk of viral transmission, unlike other unprocessed products containing FXIII. An ongoing Phase II/III study of Fibrogammin ® P in patients with congenital FXIII deficiency is being conducted to evaluate the prophylactic efficacy and long-term safety of this product. Using retrospective chart review data from subjects enrolled in the Phase II/III study, the current analysis was designed to compare spontaneous bleed-event rates prior to and after the initiation of Fibrogammin ® P prophylaxis. Seven subjects were evaluable for comparison, having received no other prophylactic FXIII-containing product during the 24 months prior to study entry. The mean annual number of spontaneous bleeds was 2.5 events per year prior to Fibrogammin ® P prophylaxis and 0.2 events per year during Fibrogammin ® P prophylaxis ( P  = 0.01). Patients reported no severe bleeds during Fibrogammin ® P therapy. This small sample supports a consistent and clinically meaningful reduction in spontaneous bleeding with prophylactic use of Fibrogammin ® P.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/79140/1/j.1365-2516.2009.02123.x.pd