Large-Angle Correlations in the Cosmic Microwave Background

It has been argued recently by Copi etal (2009) that the lack of large angular correlations of the CMB temperature field provides strong evidence against the standard, statistically isotropic, inflationary LambdaCDM cosmology. We compare various estimators of the temperature correlation function showing how they depend on assumptions of statistical isotropy and how they perform on the WMAP 5 year ILC maps with and without a sky cut. We show that the low multipole harmonics that determine the large-scale features of the temperature correlation function can be reconstructed accurately, independent of any assumptions concerning statistical isotropy, from the data that lie outside the sky cuts. The temperature correlation functions computed from our reconstructions are in good agreement with those computed from the whole sky. A Bayesian analysis of the large-scale correlations is presented which shows that the data cannot exclude the standard LambdaCDM model. We discuss the differences between our conclusions and those of Copi et al.Comment: 14page

Discovery of Quasi-Periodic Oscillations in the Recurrent Burst Emission from SGR 1806-20

We present evidence for Quasi-Periodic Oscillations (QPOs) in the recurrent outburst emission from the soft gamma repeater SGR 1806-20 using NASA's Rossi X-ray Timing Explorer (RXTE) observations. By searching a sample of 30 bursts for timing signals at the frequencies of the QPOs discovered in the 2004 December 27 giant flare from the source, we find three QPOs at 84, 103, and 648 Hz in three different bursts. The first two QPOs lie within $\sim$ 1$\: \sigma$ from the 92 Hz QPO detected in the giant flare. The third QPO lie within $\sim$ 9$\: \sigma$ from the 625 Hz QPO also detected in the same flare. The detected QPOs are found in bursts with different durations, morphologies, and brightness, and are vindicated by Monte Carlo simulations, which set a lower limit confidence interval $\geq 4.3 \sigma$. We also find evidence for candidate QPOs at higher frequencies in other bursts with lower statistical significance. The fact that we can find evidence for QPOs in the recurrent bursts at frequencies relatively close to those found in the giant flare is intriguing and can offer insight about the origin of the oscillations. We confront our finding against the available theoretical models and discuss the connection between the QPOs we report and those detected in the giant flares. The implications to the neutron star properties are also discussed.Comment: 5 pages, 2 figures, Accepted for publication in the Astrophysical Journal Letters (ApJL

Stability, Structure and Scale: Improvements in Multi-modal Vessel Extraction for SEEG Trajectory Planning

Purpose Brain vessels are among the most critical landmarks that need to be assessed for mitigating surgical risks in stereo-electroencephalography (SEEG) implantation. Intracranial haemorrhage is the most common complication associated with implantation, carrying signi cant associated morbidity. SEEG planning is done pre-operatively to identify avascular trajectories for the electrodes. In current practice, neurosurgeons have no assistance in the planning of electrode trajectories. There is great interest in developing computer assisted planning systems that can optimise the safety pro le of electrode trajectories, maximising the distance to critical structures. This paper presents a method that integrates the concepts of scale, neighbourhood structure and feature stability with the aim of improving robustness and accuracy of vessel extraction within a SEEG planning system. Methods The developed method accounts for scale and vicinity of a voxel by formulating the problem within a multi-scale tensor voting framework. Feature stability is achieved through a similarity measure that evaluates the multi-modal consistency in vesselness responses. The proposed measurement allows the combination of multiple images modalities into a single image that is used within the planning system to visualise critical vessels. Results Twelve paired datasets from two image modalities available within the planning system were used for evaluation. The mean Dice similarity coe cient was 0.89 ± 0.04, representing a statistically signi cantly improvement when compared to a semi-automated single human rater, single-modality segmentation protocol used in clinical practice (0.80 ±0.03). Conclusions Multi-modal vessel extraction is superior to semi-automated single-modality segmentation, indicating the possibility of safer SEEG planning, with reduced patient morbidity

Applicability of Perturbative QCD to Pion Virtual Compton Scattering

We study explicitly the applicability of perturbative QCD (pQCD) to the pion virtual Compton scattering. It is found that there are central-region singularities introduced by the QCD running coupling constant, in addition to the end-point singularities generally existed in other exclusive processes such as the pion form factor. We introduce a simple technique to evaluate the contributions from these singularities, so that we can arrive at a judgement that these contributions will be unharmful to the applicability of pQCD at certain energy scale, i.e., the ``work point'' which is defined to determine when pQCD is applicable to exclusive processes. The applicability of pQCD for different pion distribution amplitudes are explored in detail. We show that pQCD begins to work at 10 ${GeV}^2$. If we relax our constraint to a weak sense, the work point may be as low as 4 ${GeV}^2$.Comment: 13 Latex pages, 10 figures, to appear in PL

Flavour Changing Neutral Currents, Weak-Scale Scalars and Rare Top Decays

We examine the decays $t\rightarrow c\gamma$ and $c Z^0$ in the Standard Model with an extra scalar doublet and no discrete symmetry preventing tree-level flavour changing neutral currents. The Yukawa couplings of the new scalars are assumed to be proportional to fermion masses, evading bounds on FCNC's from the light quark sector. These rare top decays may be visible at the SSC.Comment: (some wording changed, and several references added) 13 pages, 2 figures included, uses harvmac.tex and epsf.tex, UCSD/PTH 93-0

The Data Acquisition System for the KOTO Experiment

We developed and built a new system of readout and trigger electronics, based on the waveform digitization and pipeline readout, for the KOTO experiment at J-PARC, Japan. KOTO aims at observing the rare kaon decay $K_{L}\rightarrow\pi^{0}\nu\bar{\nu}$. A total of 4000 readout channels from various detector subsystems are digitized by 14-bit 125-MHz ADC modules equipped with a 10-pole Bessel filter in order to reduce the pile-up effects. The trigger decision is made every 8-ns using the digitized waveform information. To avoid dead time, the ADC and trigger modules have pipelines in their FPGA chips to store data while waiting for the trigger decision. The KOTO experiment performed the first physics run in May 2013. The data acquisition system worked stably during the run.Comment: 5 pages,12 figures, Transactions on Nuclear Science, Proceedings of the 19th Real Time Conference, Preprin

Overtone spectra and intensities of tetrahedral molecules in boson-realization models

The stretching and bending vibrational spectrum and the intensities of infrared transitions in a tetrahedral molecule are studied in two boson-realization models, where the interactions between stretching and bending vibrations are described by a quadratic cross term and by Fermi resonance terms, called harmonically coupled and Fermi resonance boson-realization model, respectively. The later is a development of our recent model. As an example, the two models are applied to the overtone spectrum and the intensities of silicon tetrafluorde. Those models provide fits to the published experimental vibrational eigenvalues with standard deviations 1.956 cm$^{-1}$ and 0.908 cm$^{-1}$, respectively. The intensities of infrared transitions of its complete vibrations are calculated in the two models, and results show a good agreement with the observed data.Comment: 14 pages Revtex, no figure, to appear in Annals of Physic

Primary enucleation for group D retinoblastoma in the era of systemic and targeted chemotherapy: the price of retaining an eye

BACKGROUND: Chemotherapy is increasingly used as primary treatment for group D retinoblastoma, whereas primary enucleation is considered to have a diminishing role. This study aimed to compare the management course, including number of examinations under anaesthesia (EUAs), of group D patients treated by enucleation versus chemotherapy. METHODS: A retrospective analysis of 92 group D patients, of which 40 (37 unilateral) underwent primary enucleation and 52 (17 unilateral) were treated with intravenous chemotherapy. Number of EUAs was compared between the treatment groups with respect to the whole cohort, using univariate and multivariate analysis, and to unilateral cases only. RESULTS: Patients were followed up for a median of 61 months (mean: 66, range: 14-156), in which time primary enucleated patients had on average seven EUAs and chemotherapy-treated patients 21 EUAs (p<0.001). Chemotherapy, young age, bilateral disease, multifocal tumours, familial and germline retinoblastoma were found on univariate analysis to correlate with increased number of EUAs (p≤0.019). On multivariate analysis, however, only treatment type and presentation age were found significant (p≤0.001). On subanalysis of the unilateral cases, patients undergoing primary enucleation had in average seven EUAs, as compared with 16 in the chemotherapy group (p<0.001). Of the 55 unilateral-presenting patients, a new tumour developed in the fellow eye only in a single familial case. CONCLUSION: Group D patients' families should be counselled regarding the significant difference in number of EUAs following primary enucleation versus chemotherapy when deciding on a treatment strategy. In this regard, primary enucleation would be most beneficial for older patients with unilateral disease

On Smooth Orthogonal and Octilinear Drawings: Relations, Complexity and Kandinsky Drawings

We study two variants of the well-known orthogonal drawing model: (i) the smooth orthogonal, and (ii) the octilinear. Both models form an extension of the orthogonal, by supporting one additional type of edge segments (circular arcs and diagonal segments, respectively). For planar graphs of max-degree 4, we analyze relationships between the graph classes that can be drawn bendless in the two models and we also prove NP-hardness for a restricted version of the bendless drawing problem for both models. For planar graphs of higher degree, we present an algorithm that produces bi-monotone smooth orthogonal drawings with at most two segments per edge, which also guarantees a linear number of edges with exactly one segment.Comment: Appears in the Proceedings of the 25th International Symposium on Graph Drawing and Network Visualization (GD 2017