A Medical Waste Sterilizer

Sterilization of medical waste is very important for the environment, as the exposition may result in various diseases because of viral or bacterial content of the waste. There are devices developed for this purpose aiming to sterilize the waste in a form called batch process, meaning that a certain amount of waste is placed into the system and subjected to a sterilization procedure for a while and removed from the system afterwards. The procedure is repeated by the next set of waste till the whole set is sterilized. Our aim, however, is to design a device, a rotating cylindrical container having tubular lights attached to the walls inside, through which the waste is exposed to ultraviolet light as it gets rotated and moved towards the exit. The process will continue till the whole set is fed into the system. Such a device would be more effective as compared to batch processing types. The study group is asked to develop a mathematical model to analyse the effect of the number and location of tubes which will lead to maximal exposure during certain amount of time, which also needs an estimate, the sample will reside in the device before it gets discharged

Initialization Strategy for Nonlinear Systems

The Study Group was asked to provide some hints concerning a choice of initial values to be used for nonlinear algebraic systems. The group has considered the available options and outlined the pros and cons of various methods and provided some recommendations

The effect of vascular graft and human umbilical cord blood-derived CD34+ stem cell on peripheral nerve healing

AIM: There are many trials concerning peripheral nerve damage causes and treatment options. Unfortunately, nerve damage is still a major problem regarding health, social and economic issues. On this study, we used vascular graft and human cord blood derived stem cells to find an alternative treatment solution to this problem. MATERIAL AND METHODS: We used 21 female Wistar rats on our study. They were anesthetized with ketamine and we studied right hind limbs. On Group 1, we did a full layer cut on the right sciatic nerve. On Group 2, we did a full layer cut on the right sciatic nerve, and we covered synthetic vascular graft on cut area. On Group 3, we did a full layer cut on right sciatic nerve, and we covered the area with stem cell applied vascular graft. RESULTS: At the end of postoperative 8. weeks, we performed EMG on the rats. When we compared healthy and degenerated areas as a result of EMG, we found significant amplitude differences between the groups on healthy areas whereas there was no significant difference on degenerated areas between the groups. Then we re-opened the operated area again to reveal the sciatic nerve cut area, and we performed electron microscope evaluation. On the stem cell group, we observed that both the axon and the myelin sheet prevented degeneration. CONCLUSION: This study is a first on using synthetic vascular graft and cord blood derived CD34+ cells in peripheral nerve degeneration. On the tissues that were examined with electron microscope, we observed that CD34+ cells prevented both axonal and myelin sheath degeneration. Nerve tissue showed similar results to the control group, and the damage was minimal. © 2018 Ali Yilmaz, Abdullah Topcu, Cagdas Erdogan, Levent Sinan Bir, Barbaros Sahin, Gulcin Abban, Erdal Coskun, Ayca Ozkul

Job Analysis System for Civil Engineers in Construction Companies

Job research and analysis studies are the reports that detail the system andenvironmental conditions and performance of each job for obtaining higher efficiency andreducing the unit cost. In order to do the job analysis properly, information and data regardingthe job have to be evaluated accurately and realistically. The originating point of the article isbased on this definition and requirement. In the study, the established job analysis model hasbeen built on system approach. Steps of the model consist of input-preliminary preparation,process-analysis and conclusion phases.In accordance with the model suggested, a job analysis form has been developed to beused in improvement of functions of various human resources and in selection of civil engineersat manager position of construction companies during the study. The form specifies the jobprofile and personal requirements of civil engineers and gives information about time researchstudies aimed at efficiency. Form data has been collected by interviewing 50 (fifty) civilengineers at manager position working at large and medium sized construction firms, in order tobe used in job analysis discipline. In the study, information and data obtained by job analysisform have been analyzed by statistical methods and the results have been compared to similarliterature findings

Infrared renormalons and single meson production in proton-proton collisions

In this article, we investigate the contribution of the higher twist Feynman diagrams to the large-$p_T$ inclusive pion production cross section in proton-proton collisions and present the general formulae for the higher twist differential cross sections in the case of the running coupling and frozen coupling approaches. The structure of infrared renormalon singularities of the higher twist subprocess cross section and the resummed expression (the Borel sum) for it are found. We compared the resummed higher twist cross sections with the ones obtained in the framework of the frozen coupling approximation and leading twist cross section. We obtain, that ratio $R$ for all values of the transverse momentum $p_{T}$ of the pion identical equivalent to ratio $r$. It is shown that the resummed result depends on the choice of the meson wave functions used in calculation. Phenomenological effects of the obtained results are discussed.Comment: 28 pages, 13 figure

Statistical Theory for Incoherent Light Propagation in Nonlinear Media

A novel statistical approach based on the Wigner transform is proposed for the description of partially incoherent optical wave dynamics in nonlinear media. An evolution equation for the Wigner transform is derived from a nonlinear Schrodinger equation with arbitrary nonlinearity. It is shown that random phase fluctuations of an incoherent plane wave lead to a Landau-like damping effect, which can stabilize the modulational instability. In the limit of the geometrical optics approximation, incoherent, localized, and stationary wave-fields are shown to exist for a wide class of nonlinear media.Comment: 4 pages, REVTeX4. Submitted to Physical Review E. Revised manuscrip

Transcriptional down-regulation of ccr5 in a subset of HIV+ controllers and their family members.

HIV +Elite and Viremic controllers (EC/VCs) are able to control virus infection, perhaps because of host genetic determinants. We identified 16% (21 of 131) EC/VCs with CD4 +T cells with resistance specific to R5-tropic HIV, reversed after introduction of ccr5. R5 resistance was not observed in macrophages and depended upon the method of T cell activation. CD4 +T cells of these EC/VCs had lower ccr2 and ccr5 RNA levels, reduced CCR2 and CCR5 cell-surface expression, and decreased levels of secreted chemokines. T cells had no changes in chemokine receptor mRNA half-life but instead had lower levels of active transcription of ccr2 and ccr5, despite having more accessible chromatin by ATAC-seq. Other nearby genes were also down-regulated, over a region of ~500 kb on chromosome 3p21. This same R5 resistance phenotype was observed in family members of an index VC, also associated with ccr2/ccr5 down-regulation, suggesting that the phenotype is heritable

Field-portable optofluidic plasmonic biosensor for wide-field and label-free monitoring of molecular interactions

We demonstrate a field-portable optofluidic plasmonic sensing device, weighing 40 g and 7.5 cm in height, which merges plasmonic microarrays with dual-wavelength lensfree on-chip imaging for real-time monitoring of protein binding kinetics

Schubert calculus of Richardson varieties stable under spherical Levi subgroups

We observe that the expansion in the basis of Schubert cycles for $H^*(G/B)$ of the class of a Richardson variety stable under a spherical Levi subgroup is described by a theorem of Brion. Using this observation, along with a combinatorial model of the poset of certain symmetric subgroup orbit closures, we give positive combinatorial descriptions of certain Schubert structure constants on the full flag variety in type $A$. Namely, we describe $c_{u,v}^w$ when $u$ and $v$ are inverse to Grassmannian permutations with unique descents at $p$ and $q$, respectively. We offer some conjectures for similar rules in types $B$ and $D$, associated to Richardson varieties stable under spherical Levi subgroups of SO(2n+1,\C) and SO(2n,\C), respectively.Comment: Section 4 significantly shortened, and other minor changes made as suggested by referees. Final version, to appear in Journal of Algebraic Combinatoric

Lensfree optofluidic plasmonic sensor for real-time and label-free monitoring of molecular binding events over a wide field-of-view

We demonstrate a high-throughput biosensing device that utilizes microfluidics based plasmonic microarrays incorporated with dual-color on-chip imaging toward real-time and label-free monitoring of biomolecular interactions over a wide field-of-view of >20 mm^2. Weighing 40 grams with 8.8 cm in height, this biosensor utilizes an opto-electronic imager chip to record the diffraction patterns of plasmonic nanoapertures embedded within microfluidic channels, enabling real-time analyte exchange. This plasmonic chip is simultaneously illuminated by two different light-emitting-diodes that are spectrally located at the right and left sides of the plasmonic resonance mode, yielding two different diffraction patterns for each nanoaperture array. Refractive index changes of the medium surrounding the near-field of the nanostructures, e.g., due to molecular binding events, induce a frequency shift in the plasmonic modes of the nanoaperture array, causing a signal enhancement in one of the diffraction patterns while suppressing the other. Based on ratiometric analysis of these diffraction images acquired at the detector-array, we demonstrate the proof-of-concept of this biosensor by monitoring in real-time biomolecular interactions of protein A/G with immunoglobulin G (IgG) antibody. For high-throughput on-chip fabrication of these biosensors, we also introduce a deep ultra-violet lithography technique to simultaneously pattern thousands of plasmonic arrays in a cost-effective manner