308 research outputs found

    Investigating the effect of child maltreatment on early adolescent peer-on-peer sexual aggression: testing a multiple mediator model in a non-incarcerated sample of Danish adolescents

    Get PDF
    Objective: The aim of the present study was to investigate the relationship between child maltreatment and severe early adolescent peer-on-peer sexual aggression, using a multiple mediator model. Methods: The study comprised 330 male Grade 9 students with a mean age of 14.9 years (SD=0.5). Results: Estimates from the mediation model indicated significant indirect effects of child physical abuse on sexual aggression via peer influence and insecure-hostile masculinity. No significant total effect of child sexual abuse and child neglect on sexual aggression was found. Conclusions: Findings of the present study identify risk factors that are potentially changeable and therefore of value in informing the design of prevention programs aiming at early adolescent peer-on-peer sexual aggression in at-risk youth

    To retain or remove the syndesmotic screw: a review of literature

    Get PDF
    Introduction: Syndesmotic positioning screws are frequently placed in unstable ankle fractures. Many facets of adequate placement techniques have been the subject of various studies. Whether or not the syndesmosis screw should be removed prior to weight-bearing is still debated. In this study, the recent literature is reviewed concerning the need for removal of the syndesmotic screw. Materials and methods: A comprehensive literature search was conducted in the electronic databases of the Cochrane Library, Pubmed Medline and EMbase from January 2000 to October 2010. Results: A total of seven studies were identified in the literature. Most studies found no difference in outcome between retained or removed screws. Patients with screws that were broken, or showed loosening, had similar or improved outcome compared to patients with removed screws. Removal of the syndesmotic screws, when deemed necessary, is usually not performed before 8-12 weeks. Conclusion: There is paucity in randomized controlled trials on the absolute need for removal of the syndesmotic screw. However, current literature suggests that it might be reserved for intact screws that cause hardware irritation or reduced range of motion after 4-6 months

    Epizootiological. Study of sheep and goat abortion by Salmonella abortus ovis in Greece

    Get PDF
    Στην παρούσα μελέτη συγκεντρώθηκαν και ταξινομήθηκαν στοιχεία από περιστατικά αποβολών προβάτων και αιγών που διερευνήθηκαν στο Ινστιτούτο Λοιμωδών και Παρασιτικών Νοσημάτων Θεσσαλονίκης, τη δεκαετία του 1980. Από τα στοιχεία αυτά προέκυψε, ότι τα ποσοστά των θετικών στη Salmonella abortus ovis (SAO) ποιμνίων προβάτων και αιγών, που διαπιστώθηκαν με απομόνωση του βακτηρίου, κυμάνθηκαν από 1,69% μέχρι 19,35%. Τα αντίστοιχα ποσοστά των ορολογικά θετικών στη SAO ποιμνίων κυμάνθηκαν από 2,7% μέχρι 47% περίπου. Το ποσοστό των προσβεβλημένων ποιμνίων προβάτων, που διαπιστώθηκαν μετά την απομόνωση της SAO, ήταν πολύ μεγαλύτερο του αντιστοίχου ποσοστού των ποιμνίων αιγών (11,25% έναντι 6% των αιγών).The epizootiological data concerning sheep and goat abortion cases were studied between 1980-1989. The abortion cases were investigated by cultural or serological exaninations. From the affected flocks, where abortions took place, 1.69% to 19.35% were considered as infected by Salmonella abortus ovis SAO after isolation of the organism. The serological examinations of flocks with abortions, revealed a positivity to SAO of 2.7% to 47%. The infected sheep flocks, that were ascertained by isolation of SAO prevailed against the corrensponding goat herds with an average of 11.25% to 6% respectively

    Device Thrombogenicity Emulation: A Novel Method for Optimizing Mechanical Circulatory Support Device Thromboresistance

    Get PDF
    Mechanical circulatory support (MCS) devices provide both short and long term hemodynamic support for advanced heart failure patients. Unfortunately these devices remain plagued by thromboembolic complications associated with chronic platelet activation – mandating complex, lifelong anticoagulation therapy. To address the unmet need for enhancing the thromboresistance of these devices to extend their long term use, we developed a universal predictive methodology entitled Device Thrombogenicity Emulation (DTE) that facilitates optimizing the thrombogenic performance of any MCS device – ideally to a level that may obviate the need for mandatory anticoagulation

    Changes in Inflammatory Response after Endovascular Treatment for Type B Aortic Dissection

    Get PDF
    This present study aims to investigate the changes in the inflammatory markers after elective endovascular treatment of Type B aortic dissection with aneurysm, as related to different anatomical features of the dissection flap in the paravisceral perfusion. Consecutive patients with type B aortic dissections with elective endovascular stent graft repair were recruited and categorized into different groups. Serial plasma levels of cytokines (Interleukin-1β, -6, -8, -10, TNF-α), chemokines (MCP-1), and serum creatinine were monitored at pre-, peri- and post-operative stages. The length of stent graft employed in each surgery was retrieved and correlated with the change of all studied biochemical parameters. A control group of aortic dissected patients with conventional medication management was recruited for comparing the baseline biochemical parameters. In total, 22 endovascular treated and 16 aortic dissected patients with surveillance were recruited. The endovascular treated patients had comparable baseline levels as the non-surgical patients. There was no immediate or thirty day-mortality, and none of the surgical patients developed post-operative mesenteric ischaemia or clinically significant renal impairment. All surgical patients had detectable pro-inflammatory mediators, but none of the them showed any statistical significant surge in the peri-operative period except IL-1β and IL-6. Similar results were obtained when categorized into different groups. IL-1β and IL-6 showed maximal levels within hours of the endovascular procedure (range, 3.93 to 27.3 higher than baseline; p = 0.001), but returned to baseline 1 day post-operatively. The change of IL-1β and IL-6 at the stent graft deployment was statistically greater in longer stent graft (p>0.05). No significant changes were observed in the serum creatinine levels. In conclusion, elective endovascular repair of type B aortic dissection associated with insignificant changes in inflammatory mediators and creatinine. All levels fell toward basal levels post-operatively suggesting that thoracic endovascular aortic repair is rather less aggressive with insignificant inflammatory modulation
    corecore