840 research outputs found

    Concentration Gradient, Diffusion, and Flow Through Open Porous Medium Near Percolation Threshold via Computer Simulations

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    The interacting lattice gas model is used to simulate fluid flow through an open percolating porous medium with the fluid entering at the source-end and leaving from the opposite end. The shape of the steady-state concentration profile and therefore the gradient field depends on the is found to scale with the porosity according to porosity p. The root mean square (rms) displacements of fluid and its constituents (tracers) show a drift power-law behavior, in the asymptotic regime. The flux current density is found to scale with the porosity according to an exponent near 1.7.Comment: 8 figure

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    Untitled (Photograph)

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    Cluster Analysis of the Ising Model and Universal Finite-Size Scaling

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    The recent progress in the study of finite-size scaling (FSS) properties of the Ising model is briefly reviewed. We calculate the universal FSS functions for the Binder parameter gg and the magnetization distribution function p(m)p(m) for the Ising model on L1×L2L_1 \times L_2 two-dimensional lattices with tilted boundary conditions. We show that the FSS functions are universal for fixed sets of the aspect ratio L1/L2L_1/L_2 and the tilt parameter. We also study the percolating properties of the Ising model, giving attention to the effects of the aspect ratio of finite systems. We elucidate the origin of the complex structure of p(m)p(m) for the system with large aspect ratio by the multiple-percolating-cluster argument.Comment: 11 pages including 6 eps figures, elsart.sty, to appear in Physica

    Carriage Rides and Excursions: 1868-1877

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    Letters describing carriage rides and train excursions ca1870 in western NY.https://digitalcommons.brockport.edu/local_books/1016/thumbnail.jp

    Domains growth and packing properties in driven granular media subject to gravity

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    We study the dynamical properties of recently introduced frustrated lattice gas models (IFLG and Tetris) for granular media under gentle shaking. We consider both the case where grains have inter-grain surface interactions and the case where they have not, corresponding, for instance, to the presence or absence of moisture in the packs. To characterise the grains packing structure, we discuss the properties of density distribution. In particular, we consider the phenomenon of grains domains formation under compaction. New results amenable of experimental check are discussed along with some important differences between the dynamics of the present models.Comment: 7 pages, 6 postscript files for figure

    Partition function zeros for the Ising model on complete graphs and on annealed scale-free networks

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    We analyze the partition function of the Ising model on graphs of two different types: complete graphs, wherein all nodes are mutually linked and annealed scale-free networks for which the degree distribution decays as P(k)kλP(k)\sim k^{-\lambda}. We are interested in zeros of the partition function in the cases of complex temperature or complex external field (Fisher and Lee-Yang zeros respectively). For the model on an annealed scale-free network, we find an integral representation for the partition function which, in the case λ>5\lambda > 5, reproduces the zeros for the Ising model on a complete graph. For 3<λ<53<\lambda < 5 we derive the λ\lambda-dependent angle at which the Fisher zeros impact onto the real temperature axis. This, in turn, gives access to the λ\lambda-dependent universal values of the critical exponents and critical amplitudes ratios. Our analysis of the Lee-Yang zeros reveals a difference in their behaviour for the Ising model on a complete graph and on an annealed scale-free network when 3<λ<53<\lambda <5. Whereas in the former case the zeros are purely imaginary, they have a non zero real part in latter case, so that the celebrated Lee-Yang circle theorem is violated.Comment: 36 pages, 31 figure

    Gorenstein rings through face rings of manifolds

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    The face ring of a homology manifold (without boundary) modulo a generic system of parameters is studied. Its socle is computed and it is verified that a particular quotient of this ring is Gorenstein. This fact is used to prove that the sphere gg-conjecture implies all enumerative consequences of its far reaching generalization (due to Kalai) to manifolds. A special case of Kalai's manifold gg-conjecture is established for homology manifolds that have a codimension-two face whose link contains many vertices

    Validation of the SCID-hu Thy/Liv mouse model with four classes of licensed antiretrovirals.

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    BackgroundThe SCID-hu Thy/Liv mouse model of HIV-1 infection is a useful platform for the preclinical evaluation of antiviral efficacy in vivo. We performed this study to validate the model with representatives of all four classes of licensed antiretrovirals.Methodology/principal findingsEndpoint analyses for quantification of Thy/Liv implant viral load included ELISA for cell-associated p24, branched DNA assay for HIV-1 RNA, and detection of infected thymocytes by intracellular staining for Gag-p24. Antiviral protection from HIV-1-mediated thymocyte depletion was assessed by multicolor flow cytometric analysis of thymocyte subpopulations based on surface expression of CD3, CD4, and CD8. These mice can be productively infected with molecular clones of HIV-1 (e.g., the X4 clone NL4-3) as well as with primary R5 and R5X4 isolates. To determine whether results in this model are concordant with those found in humans, we performed direct comparisons of two drugs in the same class, each of which has known potency and dosing levels in humans. Here we show that second-generation antiretrovirals were, as expected, more potent than their first-generation predecessors: emtricitabine was more potent than lamivudine, efavirenz was more potent than nevirapine, and atazanavir was more potent than indinavir. After interspecies pharmacodynamic scaling, the dose ranges found to inhibit viral replication in the SCID-hu Thy/Liv mouse were similar to those used in humans. Moreover, HIV-1 replication in these mice was genetically stable; treatment of the mice with lamivudine did not result in the M184V substitution in reverse transcriptase, and the multidrug-resistant NY index case HIV-1 retained its drug-resistance substitutions.ConclusionGiven the fidelity of such comparisons, we conclude that this highly reproducible mouse model is likely to predict clinical antiviral efficacy in humans
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