718 research outputs found

    Teachers’ Competencies in Digital Game-Based Learning in Finnish Higher Education: A Case Study of The European Bio-Industry Network Game

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    The current study investigates teachers' competencies and practices in the integration process of digital game-based learning (D.G.B.L.) in the context of higher education in Finland. Based on the predefined pedagogical framework of teachers' competencies in game-based learning, which includes: 1) pedagogical area of competence, 2) technological area of competence, 3) collaborative area of competence, and 4) creative area of competence, this study aims at 'testing' and possibly 'tailoring' the framework for the higher education context and D.G.B.L. A case study approach was employed to examine teachers' competencies in the real-life context where teachers used the European Bio-Industry Network (EBIN) game in the higher education bio-economy studies. The data included documents, physical artifacts, and interviews (n=3) with the teachers who used the game in teaching during the academic year of 2019-2020. Thematic analysis was used to analyze the data. The results showed that all the four areas of competence apply to the context of higher education and D.G.B.L.; nevertheless, the areas of competence had different levels of significance with the pedagogical and technological areas of competence as the most critical. In addition, another significant finding of this study is the online teaching area of competence, which refers to the ability of teachers to integrate digital games in online courses meaningfully. Teachers should carefully plan and consider different practices for the meaningful integration of digital games in teaching. Teachers should also consider new ways of using digital games in online courses

    Multiple functional self-association interfaces in plant TIR domains

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    The self-association of Toll/interleukin-1 receptor/resistance protein (TIR) domains has been implicated in signaling in plant and animal immunity receptors. Structure-based studies identified different TIR-domain dimerization interfaces required for signaling of the plant nucleotide-binding oligomerization domain-like receptors (NLRs) L6 from flax and disease resistance protein RPS4 from Arabidopsis. Here we show that the crystal structure of the TIR domain from the Arabidopsis NLR suppressor of npr1-1, constitutive 1 (SNC1) contains both an L6-like interface involving helices alpha D and alpha E (DE interface) and an RPS4-like interface involving helices alpha A and alpha E (AE interface). Mutations in either the AE- or DE-interface region disrupt cell-death signaling activity of SNC1, L6, and RPS4 TIR domains and full-length L6 and RPS4. Self-association of L6 and RPS4 TIR domains is affected by mutations in either region, whereas only AE-interface mutations affect SNC1 TIR-domain self-association. We further show two similar interfaces in the crystal structure of the TIR domain from the Arabidopsis NLR recognition of Peronospora parasitica 1 (RPP1). These data demonstrate that both the AE and DE self-association interfaces are simultaneously required for self-association and cell-death signaling in diverse plant NLRs.11139Ysciescopu

    Search for the rare decays B0J/ψγB^{0}\to J/\psi \gamma and Bs0J/ψγB^{0}_{s} \to J/\psi \gamma

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    A search for the rare decay of a B0B^{0} or Bs0B^{0}_{s} meson into the final state J/ψγJ/\psi\gamma is performed, using data collected by the LHCb experiment in pppp collisions at s=7\sqrt{s}=7 and 88 TeV, corresponding to an integrated luminosity of 3 fb1^{-1}. The observed number of signal candidates is consistent with a background-only hypothesis. Branching fraction values larger than 1.7×1061.7\times 10^{-6} for the B0J/ψγB^{0}\to J/\psi\gamma decay mode are excluded at 90% confidence level. For the Bs0J/ψγB^{0}_{s}\to J/\psi\gamma decay mode, branching fraction values larger than 7.4×1067.4\times 10^{-6} are excluded at 90% confidence level, this is the first branching fraction limit for this decay.Comment: All figures and tables, along with any supplementary material and additional information, are available at https://lhcbproject.web.cern.ch/lhcbproject/Publications/LHCbProjectPublic/LHCb-PAPER-2015-044.htm

    First narrow-band search for continuous gravitational waves from known pulsars in advanced detector data

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    Spinning neutron stars asymmetric with respect to their rotation axis are potential sources of continuous gravitational waves for ground-based interferometric detectors. In the case of known pulsars a fully coherent search, based on matched filtering, which uses the position and rotational parameters obtained from electromagnetic observations, can be carried out. Matched filtering maximizes the signalto- noise (SNR) ratio, but a large sensitivity loss is expected in case of even a very small mismatch between the assumed and the true signal parameters. For this reason, narrow-band analysis methods have been developed, allowing a fully coherent search for gravitational waves from known pulsars over a fraction of a hertz and several spin-down values. In this paper we describe a narrow-band search of 11 pulsars using data from Advanced LIGO’s first observing run. Although we have found several initial outliers, further studies show no significant evidence for the presence of a gravitational wave signal. Finally, we have placed upper limits on the signal strain amplitude lower than the spin-down limit for 5 of the 11 targets over the bands searched; in the case of J1813-1749 the spin-down limit has been beaten for the first time. For an additional 3 targets, the median upper limit across the search bands is below the spin-down limit. This is the most sensitive narrow-band search for continuous gravitational waves carried out so far

    Evidence for the strangeness-changing weak decay ΞbΛb0π\Xi_b^-\to\Lambda_b^0\pi^-

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    Using a pppp collision data sample corresponding to an integrated luminosity of 3.0~fb1^{-1}, collected by the LHCb detector, we present the first search for the strangeness-changing weak decay ΞbΛb0π\Xi_b^-\to\Lambda_b^0\pi^-. No bb hadron decay of this type has been seen before. A signal for this decay, corresponding to a significance of 3.2 standard deviations, is reported. The relative rate is measured to be fΞbfΛb0B(ΞbΛb0π)=(5.7±1.80.9+0.8)×104{{f_{\Xi_b^-}}\over{f_{\Lambda_b^0}}}{\cal{B}}(\Xi_b^-\to\Lambda_b^0\pi^-) = (5.7\pm1.8^{+0.8}_{-0.9})\times10^{-4}, where fΞbf_{\Xi_b^-} and fΛb0f_{\Lambda_b^0} are the bΞbb\to\Xi_b^- and bΛb0b\to\Lambda_b^0 fragmentation fractions, and B(ΞbΛb0π){\cal{B}}(\Xi_b^-\to\Lambda_b^0\pi^-) is the branching fraction. Assuming fΞb/fΛb0f_{\Xi_b^-}/f_{\Lambda_b^0} is bounded between 0.1 and 0.3, the branching fraction B(ΞbΛb0π){\cal{B}}(\Xi_b^-\to\Lambda_b^0\pi^-) would lie in the range from (0.57±0.21)%(0.57\pm0.21)\% to (0.19±0.07)%(0.19\pm0.07)\%.Comment: 7 pages, 2 figures, All figures and tables, along with any supplementary material and additional information, are available at https://lhcbproject.web.cern.ch/lhcbproject/Publications/LHCbProjectPublic/LHCb-PAPER-2015-047.htm

    Predictivity of fatty liver index for non-alcoholic fatty liver disease in lean females with polycystic ovary syndrome

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    Background: Fatty liver index (FLI) is a simple tool used to predict non-alcoholic fatty liver disease (NAFLD). The role of FLI in polycystic ovary syndrome (PCOS) for the prediction of NAFLD has not been elucidated. Methods: This case-control study was from January 2014 to January 2016. Anthropometric measurements, biochemical testing, and abdominal ultrasonography were performed in 83 premenopausal otherwise healthy women with PCOS and 58 controls. NAFLD was diagnosed by ultrasound. The predictivity of FLI for NAFLD in lean and overweight/obese females with PCOS was analyzed. Results: The γ-glutamyl transferase levels were significantly higher in the females with PCOS than in the controls (p = 0.001). In women with PCOS, FLI was significantly higher in females with NAFLD comparing to those without NAFLD (47.1 ± 33.6 vs. 16.9 ± 21.6; p = 0.001). For the PCOS group, Body Mass Index had the strongest relationship with FLI (p < 0.05, r = 0.908). FLI < 30 was calculated for all the lean females. The lean females with PCOS had a significantly higher rate of NAFLD (27.5%vs. 8.8%; p = 0.041) than lean controls. Conclusion: An FLI < 30 was not sufficient to rule out NAFLD in the lean PCOS patients. Keywords: Polycystic ovary syndrome; non-alcoholic fatty liver disease; fatty liver index

    PERAN GURU PAI DALAM MENUMBUHKAN KESADARAN UKHUWAH ISLAMIYAH PADA PESERTA DIDIK KELAS VIII DI SMP NEGERI 3 MENGGALA TULANG BAWANG

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    ABSTRAK PERAN GURU PAI DALAM MENUMBUHKAN KESADARAN UKHUWAH ISLAMIYAH PADA PESERTA DIDIK DI SMP NEGERI 3 MENGGALA Oleh : Marlina Pendidikan formal pada era dewasa ini, nampaknya senantiasa lebih ditingkatkan pada segi kualitas guru, dimana guru senantiasa dituntut lebih meningkatkan keprefosionalisme, demikian juga dalam upaya meningkatkan kualitas pembentukan prilaku siswa yang sebenarnya tidak terlepas dari pendekatan dalam proses belajar mengajar.Dalam lingkungan sekolah guru memiliki peranan sangat penting bagi siswa, guru tidak hanya mengajar tetapi memberikan bimbingan/ pengarahan dan mendidik peserta didik agar peserta didik mempunyai sikap dan tingkah laku yang baik entah itu berada disekolah atau lingkungan sekitar. Penelitian ini bertujuan untuk mengetahui peran dan hambatan guru dalam menumbuhkan ukhuwah islamiyah pada peserta didik kelas VIII SMP Negeri 3 Menggala. Metode yang digunakan dalam penelitian ini adalah observasi, wawancara/ interview, dan dokumentasi. Penelitian ini merupakan penelitian kualitatif dengan pendekatan deskriptif dan dilakukan untuk menggambarkan dan menjelaskan secara sistematis, factual, dan akurat mengenai fakta yang ada di SMP Negeri 3 Menggala. Berdasarkan hasil penelitian dilapangan menunjukan bahwa Sekolah dan guru telah melaksanakan perannya namun karena adanya hambatan-hambatan yang dialami guru baik dari faktor internal maupun faktor eksternal, maka sebagian peserta didik belum memiliki kesadaran untuk menjalankan sikap ukhuwah islamiyah yakni menjalankan kegiatan yang sifatnya taat beribadah, menaati aturan sekolah, saling menghormati dan menghargai satu sama lain, tolong menolong dalam kebaikan, serta saling menjalankan dan menjaga silaturahmi. Akan tetapi, di samping itu juga guru tidak akan pernah putus asa dalam mendidik, selalu memberikan contoh yang baik dan memberikan peringatan kepada peserta didik yang bertujuan untuk menumbuhkan ukhuwah islamiyah peserta didik dalam kehidupan sehari-hari. Kata Kunci : Peran Guru, Ukhuwah Islamiyah

    Prosecuting a Judge that Enjoys Diplomatic Immunity: the Case of Judge Aydın Sefa Akay

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    ##nofultext##After the coup attempt on 15 July 2016, more than 80,000 people have been detained in Turkey. One of the most interesting incidents was undoubtedly the arrest of International Residual Mechanism for Criminal Tribunals’ (MICT) (former) Judge Aydın Sefa Akay. The main problem in this situation was whether Judge Akay enjoyed diplomatic immunity even from his own State’s jurisdiction
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