9,875 research outputs found

    Rituximab or cyclosporine in the treatment of membranous nephropathy

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    Characterisation of microstructure, defect and high-cycle-fatigue behaviour in a stainless steel joint processed by brazing

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    We report the characterisation of microstructures and high-cycle-fatigue (HCF) properties of Type 304 stainless steel joints processed by brazing. Pure copper was applied as the filler metal for brazing at 1120 °C. A two-phase microstructure was obtained within the joint region: the star-shaped precipitates and copper matrix. The precipitates with an average size of 0.43 μm were rich in iron and chromium. A fixed orientation relationship was found between the precipitates and copper matrix. The joint exhibited much higher tensile strength and HCF life when compared to pure copper. The strength enhancement can be attributed to the presence of precipitates. Furthermore, the effect of joint interface roughness as well as defects was critically investigated. The joint interface roughness showed little influence on the HCF lives. Post-examinations revealed that fatigue crack initiation and propagation occurred entirely within the joint region, hence being consistent with the similar HCF lives regardless of the pre-defined interface roughness conditions. In addition, it was found that the HCF lives decreased exponentially with the increase of initial defect area. Fractography analysis revealed that fatigue striation spacings near the crack initiation zone increased with the increase of defect area, suggesting that the larger defects result in higher crack growth rate, hence shorten the overall fatigue life.</div

    Cognitive Radio Networks: Realistic or Not?

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    A large volume of research has been conducted in the cognitive radio (CR) area the last decade. However, the deployment of a commercial CR network is yet to emerge. A large portion of the existing literature does not build on real world scenarios, hence, neglecting various important interactions of the research with commercial telecommunication networks. For instance, a lot of attention has been paid to spectrum sensing as the front line functionality that needs to be completed in an efficient and accurate manner to enable an opportunistic CR network architecture. This is necessary to detect the existence of spectrum holes without which no other procedure can be fulfilled. However, simply sensing (cooperatively or not) the energy received from a primary transmitter cannot enable correct dynamic spectrum access. For example, the low strength of a primary transmitter's signal does not assure that there will be no interference to a nearby primary receiver. In addition, the presence of a primary transmitter's signal does not mean that CR network users cannot access the spectrum since there might not be any primary receiver in the vicinity. Despite the existing elegant and clever solutions to the DSA problem no robust, implementable scheme has emerged. In this paper, we challenge the basic premises of the proposed schemes. We further argue that addressing the technical challenges we face in deploying robust CR networks can only be achieved if we radically change the way we design their basic functionalities. In support of our argument, we present a set of real-world scenarios, inspired by realistic settings in commercial telecommunications networks, focusing on spectrum sensing as a basic and critical functionality in the deployment of CRs. We use these scenarios to show why existing DSA paradigms are not amenable to realistic deployment in complex wireless environments.Comment: Work in progres
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