2,322 research outputs found
B=1 Soliton of the Nambu - Jona-Lasinio model in medium}
The solitonic sector of the Nambu - Jona-Lasinio model with baryon number one
is solved in the presence of an external medium. The calculations fully include
the polarization of both the Dirac sea and the medium as well as the Pauli
blocking effect. We found that with an increasing density the medium
destabilizes the soliton. At finite medium density the soliton mass gets
reduced whereas the mean square baryon radius shows an increase - a swelling of
the soliton. At some critical density of about two times nuclear matter density
there is no localized solution - the soliton disappears.Comment: PHYSTEX, 14 pages, 5 figures (available upon request), Preprint
RUB-TPII-26/9
Some observations on the reproductive biology of the sixgill shark Hexanchus griseus (Bonnaterre, 1788) from South African waters
Observations are made of the maturation status of 81 male and 88 female sixgill sharks Hexanchus griseus from southern African waters. Males mature at about 310 cm total length (TL) with the calcification of the terminal cartilage elements of the claspers. Determination of maturity for females was problematic, but most were fully mature by at least 420 cm TL. Newborns were captured at the same location over three consecutive summer seasons, indicating the location of a possible pupping ground.Keywords: maturity size, pupping grounds, reproduction, sixgill sharksAfrican Journal of Marine Science 2002, 24: 359–36
Cell cycle progression or translation control is not essential for vesicular stomatitis virus oncolysis of hepatocellular carcinoma.
The intrinsic oncolytic specificity of vesicular stomatitis virus (VSV) is currently being exploited to develop alternative therapeutic strategies for hepatocellular carcinoma (HCC). Identifying key regulators in diverse transduction pathways that define VSV oncolysis in cancer cells represents a fundamental prerequisite to engineering more effective oncolytic viral vectors and adjusting combination therapies. After having identified defects in the signalling cascade of type I interferon induction, responsible for attenuated antiviral responses in human HCC cell lines, we have now investigated the role of cell proliferation and translation initiation. Cell cycle progression and translation initiation factors eIF4E and eIF2Bepsilon have been recently identified as key regulators of VSV permissiveness in T-lymphocytes and immortalized mouse embryonic fibroblasts, respectively. Here, we show that in HCC, decrease of cell proliferation by cell cycle inhibitors or siRNA-mediated reduction of G(1) cyclin-dependent kinase activities (CDK4) or cyclin D1 protein expression, do not significantly alter viral growth. Additionally, we demonstrate that translation initiation factors eIF4E and eIF2Bepsilon are negligible in sustaining VSV replication in HCC. Taken together, these results indicate that cellular proliferation and the initiation phase of cellular protein synthesis are not essential for successful VSV oncolysis of HCC. Moreover, our observations indicate the importance of cell-type specificity for VSV oncolysis, an important aspect to be considered in virotherapy applications in the future
Dynamical chiral symmetry breaking by a magnetic field and multi-quark interactions
Catalysis of dynamical symmetry breaking by a constant magnetic field in
(3+1) dimensions is considered. We use the three flavour Nambu -- Jona-Lasinio
type model with 't Hooft and eight-quark interaction terms. It is shown that
the multi-quark interactions introduce new additional features to this
phenomenon: (a) the local minimum of the effective potential catalyzed by the
constant magnetic field is smoothed out with increasing strength of the field
at the characteristic scale H~10^{19} G, (b) the multi-quark forces generate
independently another local minimum associated with a larger dynamical fermion
mass. This state may exist even for multi-quark interactions with a subcritical
set of couplings, and is globally stable with respect to a further increase of
the magnetic field.Comment: 6 pages, 3 figures, added discussion and references, version to
appear in Phys.Lett.
Effects of eight-quark interactions on the hadronic vacuum and mass spectra of light mesons
The combined effective low energy QCD Lagrangians of Nambu -- Jona-Lasinio
(NJL) and 't Hooft are supplemented with eight-quark interactions. This work is
a follow-up of recent findings, namely (i) the six quark flavour determinant 't
Hooft term destabilizes the NJL vacuum, (ii) the addition of a chiral invariant
eight-fermion contact term renders the ground state of the theory globally
stable; (iii) stability constrains the values of coupling constants of the
model, meaning that even in the presence of eight-quark forces the system can
be unstable in a certain parameter region. In the present work we study a
phenomenological output of eight-quark interactions considering the mass
spectra of pseudoscalar and scalar mesons. Mixing angles are obtained and their
equivalence to the two angle approach is derived. We show that the masses of
pseudoscalars are almost neutral to the eight-quark forces. The only marked
effect of the second order in the SU(3) breaking is found in the
system. The scalars are more sensitive to the eight-quark interactions. A
strong repulsion between the singlet-octet members is the reason for the
obtained low mass of the state within the model considered.Comment: LaTeX, 46 pages, two figure
Anaerobic Carbon Monoxide Dehydrogenase Diversity in the Homoacetogenic Hindgut Microbial Communities of Lower Termites and the Wood Roach
Anaerobic carbon monoxide dehydrogenase (CODH) is a key enzyme in the Wood-Ljungdahl (acetyl-CoA) pathway for acetogenesis performed by homoacetogenic bacteria. Acetate generated by gut bacteria via the acetyl-CoA pathway provides considerable nutrition to wood-feeding dictyopteran insects making CODH important to the obligate mutualism occurring between termites and their hindgut microbiota. To investigate CODH diversity in insect gut communities, we developed the first degenerate primers designed to amplify cooS genes, which encode the catalytic (β) subunit of anaerobic CODH enzyme complexes. These primers target over 68 million combinations of potential forward and reverse cooS primer-binding sequences. We used the primers to identify cooS genes in bacterial isolates from the hindgut of a phylogenetically lower termite and to sample cooS diversity present in a variety of insect hindgut microbial communities including those of three phylogenetically-lower termites, Zootermopsis nevadensis, Reticulitermes hesperus, and Incisitermes minor, a wood-feeding cockroach, Cryptocercus punctulatus, and an omnivorous cockroach, Periplaneta americana. In total, we sequenced and analyzed 151 different cooS genes. These genes encode proteins that group within one of three highly divergent CODH phylogenetic clades. Each insect gut community contained CODH variants from all three of these clades. The patterns of CODH diversity in these communities likely reflect differences in enzyme or physiological function, and suggest that a diversity of microbial species participate in homoacetogenesis in these communities
Baryons as non-topological chiral solitons
The present review gives a survey of recent developments and applications of
the Nambu--Jona-Lasinio model with and quark flavors for the
structure of baryons. The model is an effective chiral quark theory which
incorporates the SU(N)SU(N)U(1) approximate
symmetry of Quantum chromodynamics. The approach describes the spontaneous
chiral symmetry breaking and dynamical quark mass generation. Mesons appear as
quark-antiquark excitations and baryons arise as non-topological solitons with
three valence quarks and a polarized Dirac sea. For the evaluation of the
baryon properties the present review concentrates on the non-linear
Nambu--Jona-Lasinio model with quark and Goldstone degrees of freedom which is
identical to the Chiral quark soliton model obtained from the instanton liquid
model of the QCD vacuum. In this non-linear model, a wide variety of
observables of baryons of the octet and decuplet is considered. These include,
in particular, electromagnetic, axial, pseudoscalar and pion nucleon form
factors and the related static properties like magnetic moments, radii and
coupling constants of the nucleon as well as the mass splittings and
electromagnetic form factors of hyperons. Predictions are given for the strange
form factors, the scalar form factor and the tensor charge of the nucleon.Comment: 104 pages, 27 figures as uuencoded and compressed postscript files ,
hardcopy available upon request; Prog.Part.Nucl.Phys. 37 (1996) (in print
First records of the longnose spiny dogfish Squalus blainvillei (Squalidae) and the deep-water stingray Plesiobatis daviesi (Urolophidae) from South African waters
Deep-set longline investigations of the slope waters off northern KwaZulu-Natal on the east coast of South Africa confirmed the first records of the longnose spiny dogfish Squalus blainvillei (Squalidae) and the deepwater stingray Plesiobatis daviesi (Urolophidae) from South African waters.Keywords: first records, Plesiobatis daviesi, Squalus blainvillei, South AfricaAfrican Journal of Marine Science 2002, 24: 355–35
A search for the decay modes B+/- to h+/- tau l
We present a search for the lepton flavor violating decay modes B+/- to h+/-
tau l (h= K,pi; l= e,mu) using the BaBar data sample, which corresponds to 472
million BBbar pairs. The search uses events where one B meson is fully
reconstructed in one of several hadronic final states. Using the momenta of the
reconstructed B, h, and l candidates, we are able to fully determine the tau
four-momentum. The resulting tau candidate mass is our main discriminant
against combinatorial background. We see no evidence for B+/- to h+/- tau l
decays and set a 90% confidence level upper limit on each branching fraction at
the level of a few times 10^-5.Comment: 15 pages, 7 figures, submitted to Phys. Rev.
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