DAUN SIRIH MERAH Manfaat Untuk Kesehatan

Indonesia memiliki beragam potensi alam yang memiliki kemampuan untuk pengobatan alternative bagi penyakit yang ada. Terapi pengobatan menggunakan tanaman yang ada di alam sudah banyak diterapkan saat ini karena tidak memiliki efek samping dan dapat digunakan dalam jangka panjang. Salah satu bahan alam yang mempunyai berbagai keunggulan bagi kesehatan adalah sirih merah. Sirih merah sudah dikonsumsi sejak dahulu, menjadi budaya, dan terbukti mempunyai nilai positif bagi kesehatan karena berbagai kandungan di dalamnya. Buku ini mengupas segala sisi tentang sirih merah dan pengaruhnya dalam menunjang kesehatan manusia. Kandungan senyawa bioaktif yang beragam di dalam sirih merah mampu berperan menjaga kesehatan dan dapat memperbaiki fungsi tubuh. Buku ini menjelaskan peran sirih   merah   dengan   sangat   detail.   Setiap   bab   juga dilengkapi dengan glosarium dan daftar singkatan untuk memudahkan dalam memahami isi bab tersebut. Pembahasan tentang sirih merah melalui buku ini dapat membantu pembaca untuk lebih memahami sirih merah dan memaksimalkan potensi sirih merah sehingga kesejahteraan manusia dapat ditingkatkan. Ucapan terima kasih penulis haturkan kepada semua pihak yang mendukung   penerbitan   buku   ini.   Kepada   para   team peneliti    Aretha    Medika    Utama,    Biomolecular    and Biomedical Research Center, Bandung yang telah banyak membantu dalam menyusun naskah buku sampai penerbitan

PERBANDINGAN UJI EFEKTIVITAS EKSTRAK BENGKUANG (PACHYRIZUS AROSUS) DAN DAUN SIRIH HIJAU (PIPER BETLE L.) TERHADAP BAKTERI PROPIONIBACTERIUM ACNES

Propionibacterium acnes is a gram-positive bacteria and consists of the Propionibacteriaceae family. Propionibacterium acnes is a bacteria that causes acne or acne vulgaris, a disease that is quite disturbing and gets the attention that occurs in adolescents and young adults. This research aimed to compare and determine the effectiveness of the extract of yam (Pachyrizus arosus) and green betel leaf (Piper betle L.) in inhibiting the growth of Propionibacterium acnes bacteria. The research variables were concentrations of yam extract (Pachyrizus arosus) 5%, 10%, 15%, 20% and green betel leaf (Piper betle L.) 1,5%, 3%, 5%, 7,5%. The results showed that there was an inhibiting zone against the growth of Propionibacterium acnes bacteria

PENGARUH PROMOSI KESEHATAN DENGAN MEDIA POSTER TERHADAP PENGETAHUAN IBU TENTANG KANKER PAYUDARA

According to the World Health Organization (WHO) in 2013 in Depkes RI (2015), the incidence of cancer in the year 2008 to 2012 has increased from 12.7 million cases increased to 14.2 million cases. The purpose of this study is to determine the Influence of Health Promotion By method of posters against the knowledge of mothers about breast cancer. The method in this research is queasy experimental with pre-test and post-test group design. This study was conducted in Environment II the Village of Tanjung Gusta Medan which was held in June 2019. The population of the study was 322 people, the sampling technique using random sampling with the solving formula. Methods collection data in this research use the primary data i.e. the pre-test and post-test. Data analysis was used in univariate and bivariate with the Chi-Square test. The results of this study indicate the pre-test some mothers are knowledgeable both as much as 4 people (17.4%), and post-test as many as 15 people (65.2%), knowledgeable enough at the time of the pre-test as many as 18 people (78.3%), and post-test as many as 6 people (26.1%), and less knowledgeable at the time of the pre-test as many as 1 person (4.3%), post-test as much as 2 people(8.7%). Based on this research concluded that a good knowledgeable in knowing the definition of breast cancer, the factors that cause breast cancer, how to prevent breast cancer, and how to perform a breast cancer screenin

Sporting embodiment: sports studies and the (continuing) promise of phenomenology

Whilst in recent years sports studies have addressed the calls ‘to bring the body back in’ to theorisations of sport and physical activity, the ‘promise of phenomenology’ remains largely under-realised with regard to sporting embodiment. Relatively few accounts are grounded in the ‘flesh’ of the lived sporting body, and phenomenology offers a powerful framework for such analysis. A wide-ranging, multi-stranded, and interpretatively contested perspective, phenomenology in general has been taken up and utilised in very different ways within different disciplinary fields. The purpose of this article is to consider some selected phenomenological threads, key qualities of the phenomenological method, and the potential for existentialist phenomenology in particular to contribute fresh perspectives to the sociological study of embodiment in sport and exercise. It offers one way to convey the ‘essences’, corporeal immediacy and textured sensuosity of the lived sporting body. The use of Interpretative Phenomenological Analysis (IPA) is also critically addressed. Key words: phenomenology; existentialist phenomenology; interpretative phenomenological analysis (IPA); sporting embodiment; the lived-body; Merleau-Pont

On the origin of the Norwegian lemming.

The Pleistocene glacial cycles resulted in significant changes in species distributions, and it has been discussed whether this caused increased rates of population divergence and speciation. One species that is likely to have evolved during the Pleistocene is the Norwegian lemming (Lemmus lemmus). However, the origin of this species, both in terms of when and from what ancestral taxon it evolved, has been difficult to ascertain. Here, we use ancient DNA recovered from lemming remains from a series of Late Pleistocene and Holocene sites to explore the species' evolutionary history. The results revealed considerable genetic differentiation between glacial and contemporary samples. Moreover, the analyses provided strong support for a divergence time prior to the Last Glacial Maximum (LGM), therefore likely ruling out a postglacial colonization of Scandinavia. Consequently, it appears that the Norwegian lemming evolved from a small population that survived the LGM in an ice-free Scandinavian refugium

UJI AKTIVITAS ANTIFUNGAL EKSTRAK KULIT PISANG BARANGAN (MUSA ACUMINATA COLLA.) TERHADAP PERTUMBUHAN JAMUR PITYROSPORUM OVALE

Clean and Healthy Lifestyle is essential to be endeavored by society for preventing variety of infectious diseases which one of the most common is dandruff or seborrhea sicca that caused by the growth of Pityrosporum ovale fungi. This research is indicated to provide a better alternative option using ingredient given by nature that can treat dandruff. This research using banana peel extract since it is an original fruit from North Sumatra. The result from phytochemical screening of the banana peel extract shows secondary metabolites which are saponin, tannin, steroid/tritepenoida, flavonoid and glycosides. To produce barangan banana peel extract is by maseration method. Antifungal activity test using barangan banana peel extract towards Pityrosporum ovale is done by disc diffusion method. The antifungal activity test shows the biggest result for Minimum Inhibitory Concentration (MIC) extraction concentration at 1000 mg/ml with the average diameter of 11,9 mm. According to the inhibitory scale of antifungal activity test of barangan banana peel extract towards the growth of Pityrosporum ovale is ineffective

GAMBARAN DIAGNOSTIK DAN PENATALAKSANAAN PASIEN OSTEOARTRITIS DI RUMAH SAKIT ROYAL PRIMA MEDAN TAHUN 2015

Latar belakang: Osteoarthritis adalah penyakit sendi yang paling umum. Berdasarkan studi WHO tahun 2004, OA diketahui mempengaruhi 151 juta orang di seluruh dunia, mencapai 24 juta di Asia Tenggara. Jumlah ini meningkat dari tahun ke tahun. Umur, jenis kelamin, obesitas, pekerjaan dan aktivitas fisik kerap dikaitkan sebagai faktor risiko terjadinya osteoartritis.Tujuan: Tujuan dari penelitian ini adalah untuk mengetahui gambaran diagnostik dan penatalaksanaan pasien osteoartritis di RS Royal Prima Medan tahun 2015. Metode: Penelitian ini bersifat retrospektif dan deskriptif dengan desain studi kasus. Populasi data rekam medis pasien osteoartritis tahun 2015 dengan sampel sebanyak 100 data yang diambil dengan purposive, yaitu menggunakan data lengkap. Hasil: Pada penelitian ini, kelompok umur tertinggi yang mengalami osteoartritis adalah kelompok umur 66-71 tahun sebanyak 26 orang (26%) dan paling sedikit pada kelompok umur 84-89 tahun sebanyak 1 orang (1%). Jenis kelamin terbanyak yaitu perempuan sebanyak 72 orang (72%). Lokasi sendi yang paling banyak terkena yaitu OA lutut sebanyak 71 orang (71%). Keluhan utama yaitu nyeri sendi 100%. Keluhan tambahan terbanyak adalah kaku sendi 78%. Pemeriksaan penunjang yang dilakukan adalah pemeriksaan radiologi 100%. Untuk penatalaksanaan, dokter memberikan kombinasi beberapa golongan obat. Kombinasi golongan obat yang paling banyak diberikan yaitu golongan obat OAINS + Chondrotive agent sebanyak 57 orang (57%)

UJI ANTIBAKTERI EKSTRAK BUAH TAKOKAK (SOLANUM TORVUM SWARTZ) TERHADAP PERTUMBUHAN BAKTERI PROPIONIBACTERIUM ACNES

Acne vulgaris is a disorder of the skin characterized by changes in blackheads, papules, pustules, and nodules that often occur on the face, shoulders, and back. Propionibacterium acnes is the main habitat that contributes to acne. One of the plants that have an anti-bacterial effect is takokak fruit. This study aims to study the presence or absence of anti-bacterial effects of takokak fruit extract on the growth of Propionibacterium acne bacteria. The test method used is the Diplo disk diffusion method. The fruit was extracted by maceration method using ethanol as a solvent and then diluted using 96% ethanol at a concentration of 25%, 50%, 75%, 100% while the positive control used a clindamycin suspension and negative control of distilled water. The results showed that takokak fruit extract had an antibacterial effect on Propionibacterium acnes with an average diameter inhibition zone of 16.75 mm; 18.3 mm; 18.85 mm; 21.92 mm. Positive control (clindamycin) 37,45; negative control (distilled water) has no value to prevent bacteria

Kappa Opioid receptor-induced aversion requires p38 MAPK activation in VTA dopamine neurons

The endogenous dynorphin-κ opioid receptor (KOR) system encodes the dysphoric component of the stress response and controls the risk of depression-like and addiction behaviors; however, the molecular and neural circuit mechanisms are not understood. In this study, we report that KOR activation of p38α MAPK in ventral tegmental (VTA) dopaminergic neurons was required for conditioned place aversion (CPA) in mice. Conditional genetic deletion of floxed KOR or floxed p38α MAPK by Cre recombinase expression in dopaminergic neurons blocked place aversion to the KOR agonist U50,488. Selective viral rescue by wild-type KOR expression in dopaminergic neurons of KOR(−/−) mice restored U50,488-CPA, whereas expression of a mutated form of KOR that could not initiate p38α MAPK activation did not. Surprisingly, while p38α MAPK inactivation blocked U50,488-CPA, p38α MAPK was not required for KOR inhibition of evoked dopamine release measured by fast scan cyclic voltammetry in the nucleus accumbens. In contrast, KOR activation acutely inhibited VTA dopaminergic neuron firing, and repeated exposure attenuated the opioid response. This adaptation to repeated exposure was blocked by conditional deletion of p38α MAPK, which also blocked KOR-induced tyrosine phosphorylation of the inwardly rectifying potassium channel (GIRK) subunit Kir3.1 in VTA dopaminergic neurons. Consistent with the reduced response, GIRK phosphorylation at this amino terminal tyrosine residue (Y12) enhances channel deactivation. Thus, contrary to prevailing expectations, these results suggest that κ opioid-induced aversion requires regulation of VTA dopaminergic neuron somatic excitability through a p38α MAPK effect on GIRK deactivation kinetics rather than by presynaptically inhibiting dopamine release. SIGNIFICANCE STATEMENT Kappa opioid receptor (KOR) agonists have the potential to be effective, nonaddictive analgesics, but their therapeutic utility is greatly limited by adverse effects on mood. Understanding how KOR activation produces dysphoria is key to the development of better analgesics and to defining how the endogenous dynorphin opioids produce their depression-like effects. Results in this study show that the aversive effects of κ receptor activation required arrestin-dependent p38α MAPK activation in dopamine neurons but did not require inhibition of dopamine release in the nucleus accumbens. Thus, contrary to the prevailing view, inhibition of mesolimbic dopamine release does not mediate the aversive effects of KOR activation and functionally selective κ opioids that do not activate arrestin signaling may be effective analgesics lacking dysphoric effects

Circumpolar Arctic vegetation: a hierarchic review and roadmap toward an internationally consistent approach to survey, archive and classify tundra plot data

Satellite-derived remote-sensing products are providing a modern circumpolar perspective of Arctic vegetation and its changes, but this new view is dependent on a long heritage of ground-based observations in the Arctic. Several products of the Conservation of Arctic Flora and Fauna are key to our current understanding. We review aspects of the PanArctic Flora, the Circumpolar Arctic Vegetation Map, the Arctic Biodiversity Assessment, and the Arctic Vegetation Archive (AVA) as they relate to efforts to describe and map the vegetation, plant biomass, and biodiversity of the Arctic at circumpolar, regional, landscape and plot scales. Cornerstones for all these tools are ground-based plant-species and plant-community surveys. The AVA is in progress and will store plot-based vegetation observations in a public-accessible database for vegetation classification, modeling, diversity studies, and other applications. We present the current status of the Alaska Arctic Vegetation Archive (AVA-AK), as a regional example for the panarctic archive, and with a roadmap for a coordinated international approach to survey, archive and classify Arctic vegetation. We note the need for more consistent standards of plot-based observations, and make several recommendations to improve the linkage between plot-based observations biodiversity studies and satellite-based observations of Arctic vegetation