The Group Theatre: A Reflection of the Theatre in the Thirties

Sing us a song of social significance Or you can sing until you\u27re blue Let meaning shine in every line Or we won\u27t love you. This snatch of lyrics, sung in the International Ladies Garment Workers. Union revue Pins and Needles of 1937 captures an important aspect of the literary spirit of the 1930\u27s. This decade was marked by a tendency of artists towards political and social commitment, a time when the reconstruction of American society and the menace of Fascism was a cause celebre to which artists could rally. American artists had always been interested in changing society, or at least exposing the evils they perceived. But the 1930\u27s saw a new kind of commitment and dedication. The economic breakdown caused by the depression had involved a search for social alternatives much more intense than the complacency of the prosperous 1920\u27s had witnessed. To many writers of the twenties, the social enemies were straw men, the Puritans and the Philistines, and not, significantly, the system which had nurtured them. To those writers who were disgusted by the emptiness they perceived in American during this decade, escape lay simply in flight to the bohemianism of Greenwich Village or the cultural richness of Paris. The only time the twenties had witnessed a consolidation of the artistic-intellectual community was the rally to defend Sacco and Venzettl. But the disparate elements brought together were dispersed after the execution of the anarchists, not, to converge again until the middle of the next decade. By this time, the writers had realized that their pens could be formidable weapons, and remained at home to fight

The Group Theatre: A Reflection of the Theatre in the Thirties

Sing us a song of social significance Or you can sing until you\u27re blue Let meaning shine in every line Or we won\u27t love you. This snatch of lyrics, sung in the International Ladies Garment Workers. Union revue Pins and Needles of 1937 captures an important aspect of the literary spirit of the 1930\u27s. This decade was marked by a tendency of artists towards political and social commitment, a time when the reconstruction of American society and the menace of Fascism was a cause celebre to which artists could rally. American artists had always been interested in changing society, or at least exposing the evils they perceived. But the 1930\u27s saw a new kind of commitment and dedication. The economic breakdown caused by the depression had involved a search for social alternatives much more intense than the complacency of the prosperous 1920\u27s had witnessed. To many writers of the twenties, the social enemies were straw men, the Puritans and the Philistines, and not, significantly, the system which had nurtured them. To those writers who were disgusted by the emptiness they perceived in American during this decade, escape lay simply in flight to the bohemianism of Greenwich Village or the cultural richness of Paris. The only time the twenties had witnessed a consolidation of the artistic-intellectual community was the rally to defend Sacco and Venzettl. But the disparate elements brought together were dispersed after the execution of the anarchists, not, to converge again until the middle of the next decade. By this time, the writers had realized that their pens could be formidable weapons, and remained at home to fight

Extracorporeal Membrane Oxygenation for Complex Multiorgan System Trauma

With growing experience, the indications for salvage extracorporeal membrane oxygenation continue to expand. We describe a successful application of extracorporeal support in a polytrauma patient presenting with profound hypothermia, respiratory failure, and whom was later found to have an intracranial hemorrhage. We advocate the role of salvage therapy even in patients with complex pathophysiology despite perceived relative or absolute contraindications to extracorporeal support

Modeling Human Cancer-induced Cachexia

Talbert et al. developed an inducible mouse model of cachexia caused by pancreatic cancer. This model exhibits features of the human condition, including the progressive depletion of muscle and adipose tissue associated with tumor progression

Eye-movements and ERPs reveal the time course of processing negation and remitting counterfactual worlds

The ability to update our current knowledge using contextual information is a vital process during every-day language comprehension. To understand a negated statement, readers are required to cancel real-world expectations, but are not explicitly provided with an alternative model. Thus, the question of how and when a negative context influences interpretation of later events arises. We report one eye-movement study (Exp. 1) and one ERP study (Exp. 2) investigating the effects of negation on discourse processing. Prior context depicted a real-world (RW), or negated-world (NW), while the second sentence was manipulated to create RW anomalous continuations, where events included a violation of RW knowledge, and RW-congruent continuations, where the events described were congruent with RW knowledge. Results from Experiment 1 showed that the negated discourse context did not influence initial processing of the target sentence, as reflected in participants' eye-movement behaviour. Similarly, Experiment 2 revealed that the typical N400 effect to semantic violations has not been reversed by introducing a negated-world context. However, in later processing, Experiment 1 demonstrated that the negated-world context is eventually incorporated into the representation of the sentence meaning. Thus, we suggest that discourse does not always have an immediate effect on language comprehension and discuss the results in terms of a variety of accounts of representing negation

L'épidémie de VIH à Mayotte : un reflet des défis régionaux dans l'Océan Indien

Introduction : Mayotte, département français d'outre-mer dans l'océan Indien, est confrontée à une épidémie de VIH, exacerbée par une croissance démographique rapide et une migration importante des îles voisines (Comores, Madagascar) et d’Afrique des Grands Lacs. Les conditions d'accueil des migrants y sont particulièrement précaires, avec un accès limité aux droits sociaux et aux soins de santé comparativement à la France hexagonale. L’objectif principal de l’étude était d’étudier l'épidémiologie des nouveaux diagnostics de VIH à Mayotte de 2019 à 2022. Les objectifs secondaires consistaient à analyser les facteurs de précarité socio-économique et les facteurs de risque associés à l'échec thérapeutique à 6 et 12 mois. Méthodes : Une étude rétrospective a été menée à partir des dossiers médicaux au Centre Hospitalier de Mamoudzou, analysant les nouveaux diagnostics de VIH entre 2019 et 2022. Des analyses statistiques univariées et multivariées ont identifié les facteurs de risque d'échec thérapeutique. Résultats : l'incidence du VIH a significativement augmenté, de 0,46 à 0,65 pour 1000 adultes. La proportion de nouveaux diagnostics chez les personnes originaires de Madagascar a fortement augmenté, de 25,6 % en 2019 à 45,3 % en 2022, avec une hausse également observée chez les individus originaires des Comores et de République Démocratique du Congo. 30,9% des PVVIH étaient au stade SIDA et 15,2% avaient une infection opportuniste au diagnostic. Les diagnostics lors de la grossesse, parmi les travailleurs du sexe, et les autres infections sexuellement transmissibles ont augmenté durant la période d'étude. Les personnes, vivants avec le VIH migrantes cumulaient des facteurs de grande pauvreté : logement instable dans 74% des cas, 88,4% en situation irrégulière, 39,9% dépendants de bons alimentaires et 62% vivant avec moins de 160 euros par mois. À 6 mois, 76,8% de la population totale présentaient un succès virologique sous traitement et 75,1% à 12 mois. Les facteurs de risque d'échec à M6 comprenaient le sexe, l'âge, la précarité du logement, être originaire de Madagascar, l'utilisation initiale d'inhibiteurs de protéase. Seul le diagnostic au stade SIDA était associé à l'échec en analyse multivariée. À M12, la précarité du logement et le faible niveau d'étude étaient significativement associés à l'échec.Conclusion : Mayotte est devenue le département français présentant la plus haute incidence d'infections par le VIH. L’épidémie en post COVID est marqué par un nombre de nouveaux diagnostique accru chez des patients originaires de Madagascar et de RDC. Des "épidémies dans l'épidémie" existent, avec des disparités significatives selon le lieu de naissance en termes de caractéristiques démographiques, de facteurs de risques, de vulnérabilités sociales, de sévérité de l'infection, ainsi que dans les parcours de soins et le contrôle de la charge virale. Le manque d’aides sociales et l’entrave à l’accès au système de santé de la population migrante se traduisent par un taux d’échecs de traitement bien plus élevé qu’en métropole